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The map label for this gene is aroC

Identifier: 15922605

GI number: 15922605

Start: 2282713

End: 2283885

Strand: Direct

Name: aroC

Synonym: ST2274

Alternate gene names: 15922605

Gene position: 2282713-2283885 (Clockwise)

Preceding gene: 15922604

Following gene: 15922607

Centisome position: 84.71

GC content: 38.02

Gene sequence:

>1173_bases
ATGCCAGGAAACTCATTTGGTGAATTATTTAGAATAACAACTTTCGGAGAGAGTCATGGTCCTATGGTTGGTGTCGTGAT
AGATGGAGTACCAGCAGGATTACCAATAAAAAAAGAAGACATAGAATTTGAATTGTCCTTTAGGAGACCTGGTAGACAAT
TCGTTACTGGTAGAAGAGAAAAAGATGAACCAGAAATTGTTAGTGGGGTTTATAACGGAAGAACAACAGGTGCTCCTATT
ACTATTTTGGTTAAAAATACTGATGTTATCTCATCCTTATATGAAGAAATACATTACAAGCCTAGACCTGGTCACGCTGA
TCTCCCTTATATTATGAAATACGGGTTTGAAAATTGGGATTATAGAGGTGGTGGAAGGGCAAGTGCAAGAGAAACAGTTG
GTAGGGTAGCTGCGTCTGCAATAGCAAAGAAGTTATTAATGTTAACTGATACATGGATTGCCGGGCATTTAAAAAGCCTA
GGATATGTTGAACTGAATGAACCGGTAACTTTTGAAGAGGTTTTATGTTCAAAGTACAGTCCAGTTAGAGCTAGTAAGAA
GTGGTTAGAGAAAAAATATGAAGAATTAGTAAAGCAAGCTACAGTAGAGGGTGATAGTTGGGGAGGAATAGCTGAAATAA
TAGTTAGAAATCCACCAATAGGCCTCGGAGAACCAGTATTTGATAAACTTAAAGCTGATTTGGCTAAAGCTCTATTATCT
ATTCCAGCCGTAATGGGATTTGAATATGGGCTAGGATTCAATGCAGCGAAGATGAAAGGAAGTGAGGCAAATGATGAAAT
AGTAAAGAAAGGAGATAAATACAGATGGAAATTTAATAATTCTGGAGGTATTTTGGGAGGTTTATCTACTGGAGAGGATA
TACTGGTTCGTTGCGCATTTAAACCTACTAGTTCCATAAGAAAACCCCAGAAAACAATAGATTTAAGGACTGGAGAGGAG
ACTACGATTTCTGTGATTGGAAGACATGACCCGGCTGTAGCCATTAGGGGTGTTTCCGTAGCTGAGGCAATGGTCTCTTT
AGTTATTGTCGATCATGCAATGAGAGCGGGATATATTCCTACAGTTAGGATTTCAGATGATCAAATAAAAATAATAGAGG
AAAGATGGAATAAGTATATTAGCTTATGCAAACCTACGCAGGTATCTCAGTAG

Upstream 100 bases:

>100_bases
ACAATAAACGGTATCGAAATCCTTGTAAGGCAAGCAATGGAAGCTGAAAAAATTTGGTTTGGAAAATCATTAGAAGATGA
AGAAGTGGTGAATTATCTTT

Downstream 100 bases:

>100_bases
TTAACGCTTTACCTAGCTGGTATGGTTCGTCAATGGCAGTAAATTTAACAGTTAGTGTAAGCATAAAAGAGGCAGAAAAA
TGCAAAAAGAATGATATACT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPGNSFGELFRITTFGESHGPMVGVVIDGVPAGLPIKKEDIEFELSFRRPGRQFVTGRREKDEPEIVSGVYNGRTTGAPI
TILVKNTDVISSLYEEIHYKPRPGHADLPYIMKYGFENWDYRGGGRASARETVGRVAASAIAKKLLMLTDTWIAGHLKSL
GYVELNEPVTFEEVLCSKYSPVRASKKWLEKKYEELVKQATVEGDSWGGIAEIIVRNPPIGLGEPVFDKLKADLAKALLS
IPAVMGFEYGLGFNAAKMKGSEANDEIVKKGDKYRWKFNNSGGILGGLSTGEDILVRCAFKPTSSIRKPQKTIDLRTGEE
TTISVIGRHDPAVAIRGVSVAEAMVSLVIVDHAMRAGYIPTVRISDDQIKIIEERWNKYISLCKPTQVSQ

Sequences:

>Translated_390_residues
MPGNSFGELFRITTFGESHGPMVGVVIDGVPAGLPIKKEDIEFELSFRRPGRQFVTGRREKDEPEIVSGVYNGRTTGAPI
TILVKNTDVISSLYEEIHYKPRPGHADLPYIMKYGFENWDYRGGGRASARETVGRVAASAIAKKLLMLTDTWIAGHLKSL
GYVELNEPVTFEEVLCSKYSPVRASKKWLEKKYEELVKQATVEGDSWGGIAEIIVRNPPIGLGEPVFDKLKADLAKALLS
IPAVMGFEYGLGFNAAKMKGSEANDEIVKKGDKYRWKFNNSGGILGGLSTGEDILVRCAFKPTSSIRKPQKTIDLRTGEE
TTISVIGRHDPAVAIRGVSVAEAMVSLVIVDHAMRAGYIPTVRISDDQIKIIEERWNKYISLCKPTQVSQ
>Mature_389_residues
PGNSFGELFRITTFGESHGPMVGVVIDGVPAGLPIKKEDIEFELSFRRPGRQFVTGRREKDEPEIVSGVYNGRTTGAPIT
ILVKNTDVISSLYEEIHYKPRPGHADLPYIMKYGFENWDYRGGGRASARETVGRVAASAIAKKLLMLTDTWIAGHLKSLG
YVELNEPVTFEEVLCSKYSPVRASKKWLEKKYEELVKQATVEGDSWGGIAEIIVRNPPIGLGEPVFDKLKADLAKALLSI
PAVMGFEYGLGFNAAKMKGSEANDEIVKKGDKYRWKFNNSGGILGGLSTGEDILVRCAFKPTSSIRKPQKTIDLRTGEET
TISVIGRHDPAVAIRGVSVAEAMVSLVIVDHAMRAGYIPTVRISDDQIKIIEERWNKYISLCKPTQVSQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=382, Percent_Identity=45.0261780104712, Blast_Score=277, Evalue=9e-76,
Organism=Saccharomyces cerevisiae, GI6321290, Length=362, Percent_Identity=41.9889502762431, Blast_Score=267, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_SULTO (Q96Y94)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_378274.1
- ProteinModelPortal:   Q96Y94
- SMR:   Q96Y94
- GeneID:   1460356
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST2274
- NMPDR:   fig|273063.1.peg.2442
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- BioCyc:   STOK273063:ST2274-MONOMER
- BRENDA:   4.2.3.5
- HAMAP:   MF_00300_A
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 43020; Mature: 42889

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGNSFGELFRITTFGESHGPMVGVVIDGVPAGLPIKKEDIEFELSFRRPGRQFVTGRRE
CCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCC
KDEPEIVSGVYNGRTTGAPITILVKNTDVISSLYEEIHYKPRPGHADLPYIMKYGFENWD
CCCCHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCC
YRGGGRASARETVGRVAASAIAKKLLMLTDTWIAGHLKSLGYVELNEPVTFEEVLCSKYS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHCCCC
PVRASKKWLEKKYEELVKQATVEGDSWGGIAEIIVRNPPIGLGEPVFDKLKADLAKALLS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
IPAVMGFEYGLGFNAAKMKGSEANDEIVKKGDKYRWKFNNSGGILGGLSTGEDILVRCAF
HHHHHHHHHCCCCCHHHCCCCCCCHHHHHCCCCEEEEECCCCCEEECCCCCCEEEEEEEC
KPTSSIRKPQKTIDLRTGEETTISVIGRHDPAVAIRGVSVAEAMVSLVIVDHAMRAGYIP
CCCHHHCCCHHHEEEECCCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCC
TVRISDDQIKIIEERWNKYISLCKPTQVSQ
EEEECCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PGNSFGELFRITTFGESHGPMVGVVIDGVPAGLPIKKEDIEFELSFRRPGRQFVTGRRE
CCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCC
KDEPEIVSGVYNGRTTGAPITILVKNTDVISSLYEEIHYKPRPGHADLPYIMKYGFENWD
CCCCHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCC
YRGGGRASARETVGRVAASAIAKKLLMLTDTWIAGHLKSLGYVELNEPVTFEEVLCSKYS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHCCCC
PVRASKKWLEKKYEELVKQATVEGDSWGGIAEIIVRNPPIGLGEPVFDKLKADLAKALLS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
IPAVMGFEYGLGFNAAKMKGSEANDEIVKKGDKYRWKFNNSGGILGGLSTGEDILVRCAF
HHHHHHHHHCCCCCHHHCCCCCCCHHHHHCCCCEEEEECCCCCEEECCCCCCEEEEEEEC
KPTSSIRKPQKTIDLRTGEETTISVIGRHDPAVAIRGVSVAEAMVSLVIVDHAMRAGYIP
CCCHHHCCCHHHEEEECCCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCC
TVRISDDQIKIIEERWNKYISLCKPTQVSQ
EEEECCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479