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The map label for this gene is mvk [H]

Identifier: 15922513

GI number: 15922513

Start: 2184546

End: 2185484

Strand: Direct

Name: mvk [H]

Synonym: ST2185

Alternate gene names: 15922513

Gene position: 2184546-2185484 (Clockwise)

Preceding gene: 15922511

Following gene: 15922514

Centisome position: 81.07

GC content: 33.87

Gene sequence:

>939_bases
GTGATAGAGGTAAAAGTTCCGTTAAAGCTAACTCTTTTTGGAGAACATGCAGTAGTTTATGAAAGACCAGCTATAGCATA
CACAATTTCAGAATTTCTTACTTTACGCTTTAAAGAAAGTGATAAATTTTATATTAAATCCGATAATTTGCAGATAAAAG
GAGTGAGAGTCAATATAGATGAATTTAAAATTGAAAACGAGAATATAAAACGAGTATTATCGTACATAATAGAGGGAATA
AACTATTTTGAAGCAAAGAAACCAGTAGAAATTGAAATTGAGTCTCCAGTAGAACCATCAGTAGGCTTAGGCACAAGTGC
GGGTGTAGTAGTAGGAACAGTTGCCGGTTATTCTTCATATCTAGGAATAGAACTTAGCAAAGAAGAAATTGCCAAGATCT
CTCACTCAATTGAGTTAAAAGTCCAAGGATTAGGTAGTAGAATGGATACATACACAGAAACTTTTGGTGGATTTATATAT
ATAGAGAAAGACAAGTTTGAAAAACTCTCAAGCAACTTGTCATTTTCTGCTGGCTACTTTAGGAGAGTGACGACAACAGC
TGAGATGCTTAAGAGAGTAAAGCAAATAAAAGAAAAGAAAAGAGAATTATTTGATTCAATTCTAGATACAATAGCCGAGA
TTACAATAGAAGCTAAAAAAGCATTACAAGATAACGATGAGGATAGTATAGGAGAATTAATGTATATTAATCATGGCTTA
CTCTTTTCCCTTGGGATAACAGTACCGCAAATAGATGAATTTATATCTACAACAAGAATGGCTAATGTAAAAGGCTGTAA
AATCAGTGGTGGAGGAGCTGGTGGTGCTGTAGTATGTACGAAAGATGAAAGAGCTGAACTATTATTAACTGCTATGGGAG
GAAAAGTAATTAATGCTACACCATCTTTTTTAGGAGTTCAAGTAATAAGGAGGACGTGA

Upstream 100 bases:

>100_bases
TCCTTTTGATATTTTTCAGTGTAAGGAAGTAAACCTTCTCCTTTTCCTCCCGCTAAAATGATAGCTTGCACATATAATTT
GCAACTTTACTCCTATTAAT

Downstream 100 bases:

>100_bases
TATGTTTTTGAGGAGTTTGTTGTCAAAGAAATACTTAGGAAAAAGTTAATTTTTATGCAAATATAATATGTCTCTTGTGT
GCGGAATAATTGGTATAGTA

Product: hypothetical protein

Products: NA

Alternate protein names: MK [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MIEVKVPLKLTLFGEHAVVYERPAIAYTISEFLTLRFKESDKFYIKSDNLQIKGVRVNIDEFKIENENIKRVLSYIIEGI
NYFEAKKPVEIEIESPVEPSVGLGTSAGVVVGTVAGYSSYLGIELSKEEIAKISHSIELKVQGLGSRMDTYTETFGGFIY
IEKDKFEKLSSNLSFSAGYFRRVTTTAEMLKRVKQIKEKKRELFDSILDTIAEITIEAKKALQDNDEDSIGELMYINHGL
LFSLGITVPQIDEFISTTRMANVKGCKISGGGAGGAVVCTKDERAELLLTAMGGKVINATPSFLGVQVIRRT

Sequences:

>Translated_312_residues
MIEVKVPLKLTLFGEHAVVYERPAIAYTISEFLTLRFKESDKFYIKSDNLQIKGVRVNIDEFKIENENIKRVLSYIIEGI
NYFEAKKPVEIEIESPVEPSVGLGTSAGVVVGTVAGYSSYLGIELSKEEIAKISHSIELKVQGLGSRMDTYTETFGGFIY
IEKDKFEKLSSNLSFSAGYFRRVTTTAEMLKRVKQIKEKKRELFDSILDTIAEITIEAKKALQDNDEDSIGELMYINHGL
LFSLGITVPQIDEFISTTRMANVKGCKISGGGAGGAVVCTKDERAELLLTAMGGKVINATPSFLGVQVIRRT
>Mature_312_residues
MIEVKVPLKLTLFGEHAVVYERPAIAYTISEFLTLRFKESDKFYIKSDNLQIKGVRVNIDEFKIENENIKRVLSYIIEGI
NYFEAKKPVEIEIESPVEPSVGLGTSAGVVVGTVAGYSSYLGIELSKEEIAKISHSIELKVQGLGSRMDTYTETFGGFIY
IEKDKFEKLSSNLSFSAGYFRRVTTTAEMLKRVKQIKEKKRELFDSILDTIAEITIEAKKALQDNDEDSIGELMYINHGL
LFSLGITVPQIDEFISTTRMANVKGCKISGGGAGGAVVCTKDERAELLLTAMGGKVINATPSFLGVQVIRRT

Specific function: Unknown

COG id: COG1577

COG function: function code I; Mevalonate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. Mevalonate kinase subfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323864, Length=351, Percent_Identity=23.0769230769231, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR006203
- InterPro:   IPR006205
- InterPro:   IPR006206
- InterPro:   IPR022937
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.36 [H]

Molecular weight: Translated: 34620; Mature: 34620

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVKVPLKLTLFGEHAVVYERPAIAYTISEFLTLRFKESDKFYIKSDNLQIKGVRVNID
CEEEEEEEEEEEECCEEEEEECCCHHEEHHHHHEEEEECCCEEEEEECCEEEEEEEEEHH
EFKIENENIKRVLSYIIEGINYFEAKKPVEIEIESPVEPSVGLGTSAGVVVGTVAGYSSY
HEEECCHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEHHCCCCE
LGIELSKEEIAKISHSIELKVQGLGSRMDTYTETFGGFIYIEKDKFEKLSSNLSFSAGYF
EEEEECHHHHHHHHCEEEEEEEECCCHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCHHH
RRVTTTAEMLKRVKQIKEKKRELFDSILDTIAEITIEAKKALQDNDEDSIGELMYINHGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCE
LFSLGITVPQIDEFISTTRMANVKGCKISGGGAGGAVVCTKDERAELLLTAMGGKVINAT
EEEECCCCHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCCEEEEEECCCEEEECC
PSFLGVQVIRRT
CHHHHHEEEECC
>Mature Secondary Structure
MIEVKVPLKLTLFGEHAVVYERPAIAYTISEFLTLRFKESDKFYIKSDNLQIKGVRVNID
CEEEEEEEEEEEECCEEEEEECCCHHEEHHHHHEEEEECCCEEEEEECCEEEEEEEEEHH
EFKIENENIKRVLSYIIEGINYFEAKKPVEIEIESPVEPSVGLGTSAGVVVGTVAGYSSY
HEEECCHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEHHCCCCE
LGIELSKEEIAKISHSIELKVQGLGSRMDTYTETFGGFIYIEKDKFEKLSSNLSFSAGYF
EEEEECHHHHHHHHCEEEEEEEECCCHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCHHH
RRVTTTAEMLKRVKQIKEKKRELFDSILDTIAEITIEAKKALQDNDEDSIGELMYINHGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCE
LFSLGITVPQIDEFISTTRMANVKGCKISGGGAGGAVVCTKDERAELLLTAMGGKVINAT
EEEECCCCHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCCEEEEEECCCEEEECC
PSFLGVQVIRRT
CHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA