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The map label for this gene is glmS [H]

Identifier: 15922514

GI number: 15922514

Start: 2185552

End: 2187330

Strand: Direct

Name: glmS [H]

Synonym: ST2186

Alternate gene names: 15922514

Gene position: 2185552-2187330 (Clockwise)

Preceding gene: 15922513

Following gene: 15922517

Centisome position: 81.1

GC content: 34.51

Gene sequence:

>1779_bases
ATGTCTCTTGTGTGCGGAATAATTGGTATAGTATCACTAAGGGAAAGTAAAAAACTTGCTGAAATGACAGTTTCAGCTTT
GAAAAGACTTGAATATAGAGGTTATGATAGTGTTGGTGTTGCCTCAATAAGCTCTAATGGTTTAGAAATTAGAAAGGCAA
AAGGAAAAGTAGAAGAGGTTGTTCTTCAGAAGAAGATTGAGGAAATGGAAGGATATGTGTTCTTAGGCCATACTAGATGG
GCTACTCATGGTCCTCCTACTGATTATAACGCTCATCCTCACACTGACTGTAATGGTAATATAGCTGTAGTACATAATGG
GACTATAAAGAATTATAAAGAATTAAGAGAGGAACTTGAGAGTTTAGGTCATAAATTCAAGAGTGAAACTGATACTGAAG
TCATCCCCCATTTAATTGAGGAATTTATGAAACGAGGAATGGATCCTTTTCAAGCTTTTAAGTCAGCGATAAAAAGCCTT
GAAGGTAGCTATGCAGTCTTGGCTGTTATAAACGGTGAAAGAAGAATATTCTTTGCTAAAAAAGATAATCCATTAATAAT
AGGATTAGGTGAAGGGCAAAATTTTATTGCAAGCGATATTCCAGCTTTCTTACCTTATACTAAAAGAATACTAGTTATCA
GAGATGACGAGTTAGGTTTTATAACACCAGAAACTGTTTATTTAGAAGATAAAGACGGTAATGTCATCAATATAAAAGAA
AGGATAAGAAGTGTAGATTGGGATATAGAAACTGCTAGTAAAGAAGGATATCCTCATTTTATGATTAAGGAAATTCATGA
ATCACCAAGGGCAGTAAAAGAGACAATAGACAGCCTAATGAGTGACATAGACTTAGTAGAGAAAGTTATAGAAGAAATAA
AAAATGCTGAGAGAGTTATAGTTATAGGAGCTGGAACAAGTTATCATGCTGGTCTTTACTTTTCAATAGAACTTAACAGA
CTTGGTATAAACTCTCTACCCGTAATAGCTTCTGAGTACTATAATGTGAGGAGTAAAAAAGGGGACTTAGTTTTTGCGAT
AAGTCAAAGCGGTGAAACAATAGATGTACTTCAAGGGATAAGAATGATGCGAAATAGTGGTGCTAAAATTATCTCTCTAA
CTAACGTTATAGAAAGTGCTATAGCTAGAGAAAGCGATTATAAAATCTACATGAGGGCAGGACCAGAAATTGGTGTAGCC
GCAACAAAAACTTTTACAACACAATTAGCTTCAATTCTCTTCATCCTATCCGTTTTAAAGAAGGAGAATCTAAAGAAAAT
GGAAAAAGCTCCAGATATAGTGAGAGATACAATATCACAAGTAGAAGGATTAACAAAGAAAATTGGAGAAGAATTAGCTA
AGAAAAGTAATATATACTACTTGGGTAGAGGACTCTCACTACCACTAGCAATGGAAGGTGCATTAAAAATAAAAGAAATA
GCTTATGTACATGCCGAAGCATATCCTGCTGGTGAAAGTAAGCATGGGCCAATATCTCTAGTAGAAAAAGGATTCCCAGT
AGTTATAATAAATGATGGTGAATTAACAGAACTCTTACAAAATAATTTAATGGAAATGAAGGCTAGAGGGGCTAGAATTT
ATGCAGTAAGCGTGAATAAAAAGATGAAAGATGCTGATGTTGAAATAGAGCTTCAGTCCGAGATCCCAGTATTATCTATA
GCCCCAGTAATCCAATTAATAGCATATTATGCTGCAGTAACTAAAGGATATGACCCAGATAAACCAAGAAACTTAGCTAA
AACAGTTACTGTAGAATAA

Upstream 100 bases:

>100_bases
TTTTTAGGAGTTCAAGTAATAAGGAGGACGTGATATGTTTTTGAGGAGTTTGTTGTCAAAGAAATACTTAGGAAAAAGTT
AATTTTTATGCAAATATAAT

Downstream 100 bases:

>100_bases
CTGAAAATCTCACTATTTACTTACAATATACTTTTTGCTCCTCTGAGATAGCAGTAAGGGGAAATTACTCTTCATTTTTA
GAGGGTCTTCTCTGTTAAGT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MSLVCGIIGIVSLRESKKLAEMTVSALKRLEYRGYDSVGVASISSNGLEIRKAKGKVEEVVLQKKIEEMEGYVFLGHTRW
ATHGPPTDYNAHPHTDCNGNIAVVHNGTIKNYKELREELESLGHKFKSETDTEVIPHLIEEFMKRGMDPFQAFKSAIKSL
EGSYAVLAVINGERRIFFAKKDNPLIIGLGEGQNFIASDIPAFLPYTKRILVIRDDELGFITPETVYLEDKDGNVINIKE
RIRSVDWDIETASKEGYPHFMIKEIHESPRAVKETIDSLMSDIDLVEKVIEEIKNAERVIVIGAGTSYHAGLYFSIELNR
LGINSLPVIASEYYNVRSKKGDLVFAISQSGETIDVLQGIRMMRNSGAKIISLTNVIESAIARESDYKIYMRAGPEIGVA
ATKTFTTQLASILFILSVLKKENLKKMEKAPDIVRDTISQVEGLTKKIGEELAKKSNIYYLGRGLSLPLAMEGALKIKEI
AYVHAEAYPAGESKHGPISLVEKGFPVVIINDGELTELLQNNLMEMKARGARIYAVSVNKKMKDADVEIELQSEIPVLSI
APVIQLIAYYAAVTKGYDPDKPRNLAKTVTVE

Sequences:

>Translated_592_residues
MSLVCGIIGIVSLRESKKLAEMTVSALKRLEYRGYDSVGVASISSNGLEIRKAKGKVEEVVLQKKIEEMEGYVFLGHTRW
ATHGPPTDYNAHPHTDCNGNIAVVHNGTIKNYKELREELESLGHKFKSETDTEVIPHLIEEFMKRGMDPFQAFKSAIKSL
EGSYAVLAVINGERRIFFAKKDNPLIIGLGEGQNFIASDIPAFLPYTKRILVIRDDELGFITPETVYLEDKDGNVINIKE
RIRSVDWDIETASKEGYPHFMIKEIHESPRAVKETIDSLMSDIDLVEKVIEEIKNAERVIVIGAGTSYHAGLYFSIELNR
LGINSLPVIASEYYNVRSKKGDLVFAISQSGETIDVLQGIRMMRNSGAKIISLTNVIESAIARESDYKIYMRAGPEIGVA
ATKTFTTQLASILFILSVLKKENLKKMEKAPDIVRDTISQVEGLTKKIGEELAKKSNIYYLGRGLSLPLAMEGALKIKEI
AYVHAEAYPAGESKHGPISLVEKGFPVVIINDGELTELLQNNLMEMKARGARIYAVSVNKKMKDADVEIELQSEIPVLSI
APVIQLIAYYAAVTKGYDPDKPRNLAKTVTVE
>Mature_591_residues
SLVCGIIGIVSLRESKKLAEMTVSALKRLEYRGYDSVGVASISSNGLEIRKAKGKVEEVVLQKKIEEMEGYVFLGHTRWA
THGPPTDYNAHPHTDCNGNIAVVHNGTIKNYKELREELESLGHKFKSETDTEVIPHLIEEFMKRGMDPFQAFKSAIKSLE
GSYAVLAVINGERRIFFAKKDNPLIIGLGEGQNFIASDIPAFLPYTKRILVIRDDELGFITPETVYLEDKDGNVINIKER
IRSVDWDIETASKEGYPHFMIKEIHESPRAVKETIDSLMSDIDLVEKVIEEIKNAERVIVIGAGTSYHAGLYFSIELNRL
GINSLPVIASEYYNVRSKKGDLVFAISQSGETIDVLQGIRMMRNSGAKIISLTNVIESAIARESDYKIYMRAGPEIGVAA
TKTFTTQLASILFILSVLKKENLKKMEKAPDIVRDTISQVEGLTKKIGEELAKKSNIYYLGRGLSLPLAMEGALKIKEIA
YVHAEAYPAGESKHGPISLVEKGFPVVIINDGELTELLQNNLMEMKARGARIYAVSVNKKMKDADVEIELQSEIPVLSIA
PVIQLIAYYAAVTKGYDPDKPRNLAKTVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=685, Percent_Identity=32.1167883211679, Blast_Score=319, Evalue=6e-87,
Organism=Homo sapiens, GI4826742, Length=687, Percent_Identity=33.0422125181951, Blast_Score=315, Evalue=7e-86,
Organism=Escherichia coli, GI1790167, Length=623, Percent_Identity=38.3627608346709, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1788651, Length=197, Percent_Identity=26.9035532994924, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082251, Length=332, Percent_Identity=22.289156626506, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17539970, Length=436, Percent_Identity=32.5688073394495, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17532897, Length=434, Percent_Identity=31.3364055299539, Blast_Score=198, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI17532899, Length=434, Percent_Identity=31.3364055299539, Blast_Score=198, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI17554892, Length=239, Percent_Identity=27.1966527196653, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322745, Length=460, Percent_Identity=30.6521739130435, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6323731, Length=428, Percent_Identity=23.1308411214953, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6323730, Length=206, Percent_Identity=34.9514563106796, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6323958, Length=202, Percent_Identity=23.2673267326733, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21357745, Length=693, Percent_Identity=30.8802308802309, Blast_Score=309, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65797; Mature: 65666

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVCGIIGIVSLRESKKLAEMTVSALKRLEYRGYDSVGVASISSNGLEIRKAKGKVEEV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEHHCCHHHHH
VLQKKIEEMEGYVFLGHTRWATHGPPTDYNAHPHTDCNGNIAVVHNGTIKNYKELREELE
HHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
SLGHKFKSETDTEVIPHLIEEFMKRGMDPFQAFKSAIKSLEGSYAVLAVINGERRIFFAK
HHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCEEEEEEE
KDNPLIIGLGEGQNFIASDIPAFLPYTKRILVIRDDELGFITPETVYLEDKDGNVINIKE
CCCCEEEEECCCCCHHHHCCCHHCCCCCEEEEEEECCCCEECCCEEEEECCCCCEEEHHH
RIRSVDWDIETASKEGYPHFMIKEIHESPRAVKETIDSLMSDIDLVEKVIEEIKNAERVI
HHHHCCCCEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VIGAGTSYHAGLYFSIELNRLGINSLPVIASEYYNVRSKKGDLVFAISQSGETIDVLQGI
EEECCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHH
RMMRNSGAKIISLTNVIESAIARESDYKIYMRAGPEIGVAATKTFTTQLASILFILSVLK
HHHHCCCCEEEHHHHHHHHHHCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHH
KENLKKMEKAPDIVRDTISQVEGLTKKIGEELAKKSNIYYLGRGLSLPLAMEGALKIKEI
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCEEEEHE
AYVHAEAYPAGESKHGPISLVEKGFPVVIINDGELTELLQNNLMEMKARGARIYAVSVNK
EEEEEECCCCCCCCCCCHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECC
KMKDADVEIELQSEIPVLSIAPVIQLIAYYAAVTKGYDPDKPRNLAKTVTVE
CCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECC
>Mature Secondary Structure 
SLVCGIIGIVSLRESKKLAEMTVSALKRLEYRGYDSVGVASISSNGLEIRKAKGKVEEV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEHHCCHHHHH
VLQKKIEEMEGYVFLGHTRWATHGPPTDYNAHPHTDCNGNIAVVHNGTIKNYKELREELE
HHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
SLGHKFKSETDTEVIPHLIEEFMKRGMDPFQAFKSAIKSLEGSYAVLAVINGERRIFFAK
HHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCEEEEEEE
KDNPLIIGLGEGQNFIASDIPAFLPYTKRILVIRDDELGFITPETVYLEDKDGNVINIKE
CCCCEEEEECCCCCHHHHCCCHHCCCCCEEEEEEECCCCEECCCEEEEECCCCCEEEHHH
RIRSVDWDIETASKEGYPHFMIKEIHESPRAVKETIDSLMSDIDLVEKVIEEIKNAERVI
HHHHCCCCEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VIGAGTSYHAGLYFSIELNRLGINSLPVIASEYYNVRSKKGDLVFAISQSGETIDVLQGI
EEECCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHH
RMMRNSGAKIISLTNVIESAIARESDYKIYMRAGPEIGVAATKTFTTQLASILFILSVLK
HHHHCCCCEEEHHHHHHHHHHCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHH
KENLKKMEKAPDIVRDTISQVEGLTKKIGEELAKKSNIYYLGRGLSLPLAMEGALKIKEI
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCEEEEHE
AYVHAEAYPAGESKHGPISLVEKGFPVVIINDGELTELLQNNLMEMKARGARIYAVSVNK
EEEEEECCCCCCCCCCCHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECC
KMKDADVEIELQSEIPVLSIAPVIQLIAYYAAVTKGYDPDKPRNLAKTVTVE
CCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA