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The map label for this gene is pelA

Identifier: 15922399

GI number: 15922399

Start: 2082405

End: 2083430

Strand: Direct

Name: pelA

Synonym: ST2078

Alternate gene names: 15922399

Gene position: 2082405-2083430 (Clockwise)

Preceding gene: 15922396

Following gene: 15922403

Centisome position: 77.28

GC content: 31.77

Gene sequence:

>1026_bases
ATGAAGATTTTAGAGTTTGATGATAAAAAGGGGATAATGAAATTACATATAGAGAATGAGGATGATTTATGGATATTACA
CATTATACTAAAAAAAGGTGATAGAGTAGTTGCAAAAACTACGAGAGACGTTAGTATGGGAAGAGAAAGCAGAAGAATAC
CAATGATTATCAAGTTACAAGTGGAATATACTGAATTTCAATCATTTACAAGCAGGCTCAGAATTCATGGGATAATATTA
GATGCACCAGAGAGATTCGGAATAAAAGGTTCTCATCATACAATAAACCTTGATATTGGAGATGAAATTGTAATAGAGAA
AGATCATTGGAATAAATTTGAGATCGAGAAGATAAAAAGGCAAGAGGAAAAACATCTAAAGATGCTAATAGTTCTCGTTG
ATTTTGATGAATATCTTATTGCACTTCCAATGAAGCAAGGTATAAGGATACTAGCGGAAAAATCATTAAGAACCCCAAAT
AAGGAAGAAGAAAATATCATAGAAGATAATGCGAAAGAAGTTGCTAATGAAGTACTTTCCTATGCAGAATCCTTAGGTAT
AGAAGTTGTATTACTTGCAGGACCAGGGCCTTTTAAGGAAATAGTATCCAATTTTTTAAAGAATATAAAACTTTACGTAG
ATAGTGTATCCTCAGCTACAAGAAGTGGACTAAATGAAATTTTGAAAAGAGATATAATAGATCAGATCAGCAGAGATTAC
GAAATTTCAGAAGAAACCAAGATAATGGAAAAAATAATGGAAAATTTGGCTAAAAACACTGGATTAGTGGCATATGGAAA
GGAGGAAGTTAAGAAAAGTGCAGAATACGGTGCTGTAGATAAATTGCTAGTAATTGAGGATCTTTTATCTTCAGATGAAG
AAGAGAGAATGGAAATTGAGAAGATAATGGAAGAAGTAGAAAATAAAAACGGGAGAGTTTTGATAGTTCCTAAAGATTCT
CCTATCTATTATGAAGTAAGAAATCTCACTGGACTGATAGCTTTACTTAGATTTAGAATAAACTAA

Upstream 100 bases:

>100_bases
GGTCTTCAAAACTCTCAACTTCTACTTCATACACTTTTGGTAGGTCATTTTCATCTACATTAGTTATAATTATCACTATC
TCTCGTATAAATTATGTATT

Downstream 100 bases:

>100_bases
CTTTTCAGAAATCCTTAGTCTTCTCGAGTCTGGATGCTCTTCAACGAGCCAAATTTCATCAGCATTAATTACGTTGACAA
ATTCTGGAGAGACACTCCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKILEFDDKKGIMKLHIENEDDLWILHIILKKGDRVVAKTTRDVSMGRESRRIPMIIKLQVEYTEFQSFTSRLRIHGIIL
DAPERFGIKGSHHTINLDIGDEIVIEKDHWNKFEIEKIKRQEEKHLKMLIVLVDFDEYLIALPMKQGIRILAEKSLRTPN
KEEENIIEDNAKEVANEVLSYAESLGIEVVLLAGPGPFKEIVSNFLKNIKLYVDSVSSATRSGLNEILKRDIIDQISRDY
EISEETKIMEKIMENLAKNTGLVAYGKEEVKKSAEYGAVDKLLVIEDLLSSDEEERMEIEKIMEEVENKNGRVLIVPKDS
PIYYEVRNLTGLIALLRFRIN

Sequences:

>Translated_341_residues
MKILEFDDKKGIMKLHIENEDDLWILHIILKKGDRVVAKTTRDVSMGRESRRIPMIIKLQVEYTEFQSFTSRLRIHGIIL
DAPERFGIKGSHHTINLDIGDEIVIEKDHWNKFEIEKIKRQEEKHLKMLIVLVDFDEYLIALPMKQGIRILAEKSLRTPN
KEEENIIEDNAKEVANEVLSYAESLGIEVVLLAGPGPFKEIVSNFLKNIKLYVDSVSSATRSGLNEILKRDIIDQISRDY
EISEETKIMEKIMENLAKNTGLVAYGKEEVKKSAEYGAVDKLLVIEDLLSSDEEERMEIEKIMEEVENKNGRVLIVPKDS
PIYYEVRNLTGLIALLRFRIN
>Mature_341_residues
MKILEFDDKKGIMKLHIENEDDLWILHIILKKGDRVVAKTTRDVSMGRESRRIPMIIKLQVEYTEFQSFTSRLRIHGIIL
DAPERFGIKGSHHTINLDIGDEIVIEKDHWNKFEIEKIKRQEEKHLKMLIVLVDFDEYLIALPMKQGIRILAEKSLRTPN
KEEENIIEDNAKEVANEVLSYAESLGIEVVLLAGPGPFKEIVSNFLKNIKLYVDSVSSATRSGLNEILKRDIIDQISRDY
EISEETKIMEKIMENLAKNTGLVAYGKEEVKKSAEYGAVDKLLVIEDLLSSDEEERMEIEKIMEEVENKNGRVLIVPKDS
PIYYEVRNLTGLIALLRFRIN

Specific function: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has end

COG id: COG1537

COG function: function code R; Predicted RNA-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic release factor 1 family. Pelota subfamily

Homologues:

Organism=Homo sapiens, GI31880783, Length=363, Percent_Identity=23.1404958677686, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17554648, Length=359, Percent_Identity=21.1699164345404, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324327, Length=368, Percent_Identity=23.3695652173913, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17136914, Length=369, Percent_Identity=23.3062330623306, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PELO_SULTO (Q96YU9)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_378068.1
- ProteinModelPortal:   Q96YU9
- SMR:   Q96YU9
- GeneID:   1460143
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST2078
- NMPDR:   fig|273063.1.peg.2236
- HOGENOM:   HBG646058
- OMA:   MKLVRKD
- ProtClustDB:   CLSK802548
- BioCyc:   STOK273063:ST2078-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01853
- InterPro:   IPR005140
- InterPro:   IPR005141
- InterPro:   IPR005142
- InterPro:   IPR004405
- PANTHER:   PTHR10853
- TIGRFAMs:   TIGR00111

Pfam domain/function: PF03463 eRF1_1; PF03464 eRF1_2; PF03465 eRF1_3

EC number: NA

Molecular weight: Translated: 39390; Mature: 39390

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILEFDDKKGIMKLHIENEDDLWILHIILKKGDRVVAKTTRDVSMGRESRRIPMIIKLQ
CCCEEECCCCCEEEEEECCCCCEEEEEEEECCCCEEEEECCHHHHCCCCCCCCCEEEEEE
VEYTEFQSFTSRLRIHGIILDAPERFGIKGSHHTINLDIGDEIVIEKDHWNKFEIEKIKR
EEHHHHHHHHHHHEEEEEEEECCHHCCCCCCCEEEEEECCCEEEEECCCCCCHHHHHHHH
QEEKHLKMLIVLVDFDEYLIALPMKQGIRILAEKSLRTPNKEEENIIEDNAKEVANEVLS
HHHHHEEEEEEEEECCHHHEECCHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHH
YAESLGIEVVLLAGPGPFKEIVSNFLKNIKLYVDSVSSATRSGLNEILKRDIIDQISRDY
HHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EISEETKIMEKIMENLAKNTGLVAYGKEEVKKSAEYGAVDKLLVIEDLLSSDEEERMEIE
CCCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHH
KIMEEVENKNGRVLIVPKDSPIYYEVRNLTGLIALLRFRIN
HHHHHHHCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKILEFDDKKGIMKLHIENEDDLWILHIILKKGDRVVAKTTRDVSMGRESRRIPMIIKLQ
CCCEEECCCCCEEEEEECCCCCEEEEEEEECCCCEEEEECCHHHHCCCCCCCCCEEEEEE
VEYTEFQSFTSRLRIHGIILDAPERFGIKGSHHTINLDIGDEIVIEKDHWNKFEIEKIKR
EEHHHHHHHHHHHEEEEEEEECCHHCCCCCCCEEEEEECCCEEEEECCCCCCHHHHHHHH
QEEKHLKMLIVLVDFDEYLIALPMKQGIRILAEKSLRTPNKEEENIIEDNAKEVANEVLS
HHHHHEEEEEEEEECCHHHEECCHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHH
YAESLGIEVVLLAGPGPFKEIVSNFLKNIKLYVDSVSSATRSGLNEILKRDIIDQISRDY
HHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EISEETKIMEKIMENLAKNTGLVAYGKEEVKKSAEYGAVDKLLVIEDLLSSDEEERMEIE
CCCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHH
KIMEEVENKNGRVLIVPKDSPIYYEVRNLTGLIALLRFRIN
HHHHHHHCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479