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The map label for this gene is tpiA

Identifier: 15922349

GI number: 15922349

Start: 2045425

End: 2046114

Strand: Direct

Name: tpiA

Synonym: ST2030

Alternate gene names: 15922349

Gene position: 2045425-2046114 (Clockwise)

Preceding gene: 15922347

Following gene: 15922354

Centisome position: 75.9

GC content: 34.64

Gene sequence:

>690_bases
GTGAAACCCCCTATAATATTAATCAACTACAAGGCATATGAAAATTCCTACGGAGAAAAGGGAGTAGAAATATCTAAAAA
AATAGAGAAAGTTAGCAAGGACTACGGGGTACCAATTATTATATCAGTTCCAGCAACAATGATATACAAACTCTCTCAAA
TTTTGGAAATACCAGTATACGCACAACATGTTGATGCATTAAGACATGGAGCGCATACTGGTGCAATATTACCAGAGATG
ATAAAAGATGCTGGAGCTAAGGGATCATTACTTAATCATAGCGAAAGAAAAATTAGATTAGATGAAATACATGAGGCTGT
TACAAGGATAAGAGATTTAGGATTAGAGAGTGTTGTTTGTGCTGACTCTTATGAATTAGTTCATCCTCTAGCATTACTTA
AACCTAACGCTATACTTATAGAACCTCCAGAATTAATCGGAAGTGGAAGAGCAGTATCTAAAGAAAAACCAGAAGTTATA
ACAAGAGCAGTTAACGAGATAAAAAAGGTAGAAGGAGTTTACCTAATCGCTGGAGCTGGGATTACAACAGGTGAAGATGT
ATATAAAGCAATTGAATTAGGAGCTGATGGTATTGGTGTTGCTAGTGCAGTAATGAAATCATCAACGCCAGAAAAAATAG
TAGAAGATTTCATTATAAACGCTTTAAAAGCTATTGATAGAAAGAAATAA

Upstream 100 bases:

>100_bases
ACACAAACAATGTTATTTTCTAATATTCCAACAGCTGAAGGTCTTTTAACAGCCAAATCGATACCACAAAATTTCAATAT
TTCACACCAGAGAAAATATT

Downstream 100 bases:

>100_bases
AATCAATAACTATATCAAAATAATTCCTATATTTCTCAAAAATTTTAATCAATATTTCTTTTCTATTTACAGATTCAGTA
TATTGAATAAGGTATAAAGA

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKPPIILINYKAYENSYGEKGVEISKKIEKVSKDYGVPIIISVPATMIYKLSQILEIPVYAQHVDALRHGAHTGAILPEM
IKDAGAKGSLLNHSERKIRLDEIHEAVTRIRDLGLESVVCADSYELVHPLALLKPNAILIEPPELIGSGRAVSKEKPEVI
TRAVNEIKKVEGVYLIAGAGITTGEDVYKAIELGADGIGVASAVMKSSTPEKIVEDFIINALKAIDRKK

Sequences:

>Translated_229_residues
MKPPIILINYKAYENSYGEKGVEISKKIEKVSKDYGVPIIISVPATMIYKLSQILEIPVYAQHVDALRHGAHTGAILPEM
IKDAGAKGSLLNHSERKIRLDEIHEAVTRIRDLGLESVVCADSYELVHPLALLKPNAILIEPPELIGSGRAVSKEKPEVI
TRAVNEIKKVEGVYLIAGAGITTGEDVYKAIELGADGIGVASAVMKSSTPEKIVEDFIINALKAIDRKK
>Mature_229_residues
MKPPIILINYKAYENSYGEKGVEISKKIEKVSKDYGVPIIISVPATMIYKLSQILEIPVYAQHVDALRHGAHTGAILPEM
IKDAGAKGSLLNHSERKIRLDEIHEAVTRIRDLGLESVVCADSYELVHPLALLKPNAILIEPPELIGSGRAVSKEKPEVI
TRAVNEIKKVEGVYLIAGAGITTGEDVYKAIELGADGIGVASAVMKSSTPEKIVEDFIINALKAIDRKK

Specific function: Unknown

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TPIS_SULTO (Q96YZ9)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_378018.1
- ProteinModelPortal:   Q96YZ9
- SMR:   Q96YZ9
- GeneID:   1460092
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST2030
- NMPDR:   fig|273063.1.peg.2186
- HOGENOM:   HBG297256
- OMA:   VEPPELI
- ProtClustDB:   PRK04302
- BioCyc:   STOK273063:ST2030-MONOMER
- BRENDA:   5.3.1.1
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00147_A
- InterPro:   IPR013785
- InterPro:   IPR008867
- InterPro:   IPR000652
- InterPro:   IPR022891
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR21139
- TIGRFAMs:   TIGR00419

Pfam domain/function: PF05690 ThiG; PF00121 TIM; SSF51351 Triophos_ismrse

EC number: =5.3.1.1

Molecular weight: Translated: 24898; Mature: 24898

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00171 TIM_1; PS51440 TIM_2

Important sites: ACT_SITE 93-93 ACT_SITE 141-141 BINDING 9-9 BINDING 11-11

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPPIILINYKAYENSYGEKGVEISKKIEKVSKDYGVPIIISVPATMIYKLSQILEIPVY
CCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCHH
AQHVDALRHGAHTGAILPEMIKDAGAKGSLLNHSERKIRLDEIHEAVTRIRDLGLESVVC
HHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHEEHHHHHHHHHHHHHCCCHHEEE
ADSYELVHPLALLKPNAILIEPPELIGSGRAVSKEKPEVITRAVNEIKKVEGVYLIAGAG
CCCHHHHHHHHHHCCCEEEEECHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCC
ITTGEDVYKAIELGADGIGVASAVMKSSTPEKIVEDFIINALKAIDRKK
CCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPPIILINYKAYENSYGEKGVEISKKIEKVSKDYGVPIIISVPATMIYKLSQILEIPVY
CCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCHH
AQHVDALRHGAHTGAILPEMIKDAGAKGSLLNHSERKIRLDEIHEAVTRIRDLGLESVVC
HHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHEEHHHHHHHHHHHHHCCCHHEEE
ADSYELVHPLALLKPNAILIEPPELIGSGRAVSKEKPEVITRAVNEIKKVEGVYLIAGAG
CCCHHHHHHHHHHCCCEEEEECHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCC
ITTGEDVYKAIELGADGIGVASAVMKSSTPEKIVEDFIINALKAIDRKK
CCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479