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The map label for this gene is lplA [H]

Identifier: 15922212

GI number: 15922212

Start: 1901716

End: 1902840

Strand: Direct

Name: lplA [H]

Synonym: ST1896

Alternate gene names: 15922212

Gene position: 1901716-1902840 (Clockwise)

Preceding gene: 15922211

Following gene: 15922214

Centisome position: 70.57

GC content: 32.89

Gene sequence:

>1125_bases
GTGAGAAACTACAGTGCAAGAGGCTATGAAATGTCCTGGAGGTTTATTTCCCTCCCTCCTCAAGACGGCTATCATATGGT
AACATCTTTTGTAGCTGTAGCTGATTATGTCTCAAGAGGAGGGAAAAACACACTTTTAGTTTTTTACTCTGATAAACCTT
TTGTTAATGTTGGAGTTCATCAAGAAGTATGGCTAGAAGTAAACCTTGAATTTACTAAGAAAATGGGTATTCCTGTAGTT
AGAAGAGATCTTGGCGGTGGAACAGTAGTTATTACACCCGGAGAACATGATTACTTTATTGTAGTAAAAGCCGATGAAGC
ACCTTCTAGTCCTAAAGCACTTTATGAAAAATACCTTACCCCAGTTGTAAATGTGTTAAAATCTTACGGTATTAACGCAC
AGCTTAGAGATCAGGATATAGTAGTAAACGGTAAGAAAATTAGTGGAAATGGCGCAATGACCTATAATAAGGCAGTTGTT
ATTACTGGTAATATTTTACTTAGCCTTGATGTAGATTTAATAAGTAAATGTATTAGAGTACCTACAGAAAAATTCAGAGA
TAAAATGGCTAAAGAAATGAGTGACTGGCTAACAAGCCTGGAAAAAGAATTAGGATATATTCCACCTAGGGAAGAGATTA
ATAAAAAGTTAAAAGAAGAATTTGAAAAATCTTTAGGAGTTAAGTTTGAAGAGGCTAATTTAACACCAGAGGAAATAGAA
CTTTGGGACAGATTAGCTAAAGAGAAGATGAATGAAGAGTGGATTTATTACAAAGATAATAGACATCCAGAATTACATAC
AGAAAGATGTGTTAAAATTAATAGTGCTGTTGCTTTATGTCACCTAGATTATAAAGCAAGAAAACTAGTTAGGATTACAG
TAAAAATAGTAAATAAGAAATTTGATGAAGTTTCTATTTCAGGTGACTTCTTTATAATGTCTCCGAAAGACTTTTTAGAG
TATTTAGAAGATTCGTTAAAAGGAGCTAGCGTCTCTGATTTTGAAAAAATTATAAGAAAAGTGTTTGAAGAAAAGAAACC
AGTAATATTTGGTTTTACCGCAGACGATCTAGTTAATGCGTTTAAAGAAATCTTAAATAAACCAGAAGTTCAAGAAGTTA
TATAG

Upstream 100 bases:

>100_bases
AAGGGATGGTTAGTAAAGATGAAAGTTAACAATCCAGAAGAGCTTAAGCAATTGGTTACTGGAAGCGCAGCAGTATCTAA
ATTAACTGAACTGATTAATA

Downstream 100 bases:

>100_bases
ATAAGACAGCTAATATTTCTCTTTCACCTACACTTCCTAATAACGACAAAGCATCCACAACAGGAAGGAACCCGATATTT
TTCTCAGCCATGAGTAATCT

Product: lipoate-protein ligase

Products: NA

Alternate protein names: Lipoate--protein ligase subunit 1 [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MRNYSARGYEMSWRFISLPPQDGYHMVTSFVAVADYVSRGGKNTLLVFYSDKPFVNVGVHQEVWLEVNLEFTKKMGIPVV
RRDLGGGTVVITPGEHDYFIVVKADEAPSSPKALYEKYLTPVVNVLKSYGINAQLRDQDIVVNGKKISGNGAMTYNKAVV
ITGNILLSLDVDLISKCIRVPTEKFRDKMAKEMSDWLTSLEKELGYIPPREEINKKLKEEFEKSLGVKFEEANLTPEEIE
LWDRLAKEKMNEEWIYYKDNRHPELHTERCVKINSAVALCHLDYKARKLVRITVKIVNKKFDEVSISGDFFIMSPKDFLE
YLEDSLKGASVSDFEKIIRKVFEEKKPVIFGFTADDLVNAFKEILNKPEVQEVI

Sequences:

>Translated_374_residues
MRNYSARGYEMSWRFISLPPQDGYHMVTSFVAVADYVSRGGKNTLLVFYSDKPFVNVGVHQEVWLEVNLEFTKKMGIPVV
RRDLGGGTVVITPGEHDYFIVVKADEAPSSPKALYEKYLTPVVNVLKSYGINAQLRDQDIVVNGKKISGNGAMTYNKAVV
ITGNILLSLDVDLISKCIRVPTEKFRDKMAKEMSDWLTSLEKELGYIPPREEINKKLKEEFEKSLGVKFEEANLTPEEIE
LWDRLAKEKMNEEWIYYKDNRHPELHTERCVKINSAVALCHLDYKARKLVRITVKIVNKKFDEVSISGDFFIMSPKDFLE
YLEDSLKGASVSDFEKIIRKVFEEKKPVIFGFTADDLVNAFKEILNKPEVQEVI
>Mature_374_residues
MRNYSARGYEMSWRFISLPPQDGYHMVTSFVAVADYVSRGGKNTLLVFYSDKPFVNVGVHQEVWLEVNLEFTKKMGIPVV
RRDLGGGTVVITPGEHDYFIVVKADEAPSSPKALYEKYLTPVVNVLKSYGINAQLRDQDIVVNGKKISGNGAMTYNKAVV
ITGNILLSLDVDLISKCIRVPTEKFRDKMAKEMSDWLTSLEKELGYIPPREEINKKLKEEFEKSLGVKFEEANLTPEEIE
LWDRLAKEKMNEEWIYYKDNRHPELHTERCVKINSAVALCHLDYKARKLVRITVKIVNKKFDEVSISGDFFIMSPKDFLE
YLEDSLKGASVSDFEKIIRKVFEEKKPVIFGFTADDLVNAFKEILNKPEVQEVI

Specific function: Lipoate-protein ligase catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. This subunit can alone only catalyze the lipoat

COG id: COG0095

COG function: function code H; Lipoate-protein ligase A

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lplA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.7.7.63 [H]

Molecular weight: Translated: 42884; Mature: 42884

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNYSARGYEMSWRFISLPPQDGYHMVTSFVAVADYVSRGGKNTLLVFYSDKPFVNVGVH
CCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCC
QEVWLEVNLEFTKKMGIPVVRRDLGGGTVVITPGEHDYFIVVKADEAPSSPKALYEKYLT
EEEEEEEEEEEHHHCCCCEEEEECCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHH
PVVNVLKSYGINAQLRDQDIVVNGKKISGNGAMTYNKAVVITGNILLSLDVDLISKCIRV
HHHHHHHHCCCCCEECCCEEEEECEEECCCCCEEECCEEEEECCEEEEECHHHHHHHHHC
PTEKFRDKMAKEMSDWLTSLEKELGYIPPREEINKKLKEEFEKSLGVKFEEANLTPEEIE
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHH
LWDRLAKEKMNEEWIYYKDNRHPELHTERCVKINSAVALCHLDYKARKLVRITVKIVNKK
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHEECCEEEEEECCHHHHHHHHHHHHHHHCC
FDEVSISGDFFIMSPKDFLEYLEDSLKGASVSDFEKIIRKVFEEKKPVIFGFTADDLVNA
CCEEEECCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHH
FKEILNKPEVQEVI
HHHHHCCCCHHHCC
>Mature Secondary Structure
MRNYSARGYEMSWRFISLPPQDGYHMVTSFVAVADYVSRGGKNTLLVFYSDKPFVNVGVH
CCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCC
QEVWLEVNLEFTKKMGIPVVRRDLGGGTVVITPGEHDYFIVVKADEAPSSPKALYEKYLT
EEEEEEEEEEEHHHCCCCEEEEECCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHH
PVVNVLKSYGINAQLRDQDIVVNGKKISGNGAMTYNKAVVITGNILLSLDVDLISKCIRV
HHHHHHHHCCCCCEECCCEEEEECEEECCCCCEEECCEEEEECCEEEEECHHHHHHHHHC
PTEKFRDKMAKEMSDWLTSLEKELGYIPPREEINKKLKEEFEKSLGVKFEEANLTPEEIE
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHH
LWDRLAKEKMNEEWIYYKDNRHPELHTERCVKINSAVALCHLDYKARKLVRITVKIVNKK
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHEECCEEEEEECCHHHHHHHHHHHHHHHCC
FDEVSISGDFFIMSPKDFLEYLEDSLKGASVSDFEKIIRKVFEEKKPVIFGFTADDLVNA
CCEEEECCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHH
FKEILNKPEVQEVI
HHHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11029001 [H]