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The map label for this gene is ybiK [C]

Identifier: 15922139

GI number: 15922139

Start: 1838896

End: 1839711

Strand: Reverse

Name: ybiK [C]

Synonym: ST1827

Alternate gene names: 15922139

Gene position: 1839711-1838896 (Counterclockwise)

Preceding gene: 15922140

Following gene: 161751091

Centisome position: 68.27

GC content: 39.09

Gene sequence:

>816_bases
ATGAAATACACAAAACCCGTTTTAGTTGTCCATGGAGGAGCTGGAGATTGGAGTAAAAGAGACTATGAAAAGGGACTTAC
AGAGATCAAAAAAACGTTAGAAAGGGGTTATGAAGAATTTAAAAAAGGTAGTGCTATTGAAGCTGTTGTTGAGGCTATCG
CATATATGGAGGACTCTGGAGTATTTGATGCTGGTATAGGGAGCGTTAAGAACTCTGAAGGAGAAGTGGAAATGGATGCT
GGAATTATGCATGGTAATAGTTGGAAAGTAGGTGCTGTGGCTTCGGTTAAGGCTAAAAATCCCATAAAAGAAGCACTAAA
AGTTATGCTTGACGGTAGACATGTCCTTTTAGTTGGCGAAAGGGGTGAAAGGTCGATAACCAATTTTATTGGAAATAACG
GTGGAGATACTGTCGGTGCTGTTGCCTTAGACGAACAAGGTAATTTAGTAGCTGGGACAAGTACTGGAGGAATTTCTGGC
AAATTACCAGGTAGAGTTGGTGACTCCCCAATACCTGGTGCTGGATACTATGCAACTCCTAGAGTTGCAGTTTCTTCTAC
TGGTATTGGTGAAATTATTCTTAGGATTTTACCGGCTAAAGAAGTAGATATGTTAGTTTCCATGGGTTTCTCAATAGAGG
ATTCTGTTAGGGCTGTTATCAATAAGATTACTGAACTATTTGGCAAGAGTAATGTAGGCTTAATTGGGATAGATTATAAA
GGATATGCTACTGCTTATTATAACACTGTTGGAATGGCAAGGGGAGTAAAGGATAAGAATATAGTTAGAGTCTTTGTTTT
TGAGGGAGAAATCTAA

Upstream 100 bases:

>100_bases
ATTGGCTTGGCTATAGGACCAGAAACTCTAAAGGTAAATGAATTAAAAATAAGTTAATTTTTTTCAAAACCTTTTCTTAT
TTCGACTCTTCTTTTCTATT

Downstream 100 bases:

>100_bases
TTGTGGAGAGGCATCGCTATCATTTACGCTTCAAAGAGAGATATTGCAGACAAACTTAAGGAGATACTGAAAGAATATCC
AGTATATATCTTTAAATATT

Product: L-asparaginase

Products: NA

Alternate protein names: L-asparagine amidohydrolase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MKYTKPVLVVHGGAGDWSKRDYEKGLTEIKKTLERGYEEFKKGSAIEAVVEAIAYMEDSGVFDAGIGSVKNSEGEVEMDA
GIMHGNSWKVGAVASVKAKNPIKEALKVMLDGRHVLLVGERGERSITNFIGNNGGDTVGAVALDEQGNLVAGTSTGGISG
KLPGRVGDSPIPGAGYYATPRVAVSSTGIGEIILRILPAKEVDMLVSMGFSIEDSVRAVINKITELFGKSNVGLIGIDYK
GYATAYYNTVGMARGVKDKNIVRVFVFEGEI

Sequences:

>Translated_271_residues
MKYTKPVLVVHGGAGDWSKRDYEKGLTEIKKTLERGYEEFKKGSAIEAVVEAIAYMEDSGVFDAGIGSVKNSEGEVEMDA
GIMHGNSWKVGAVASVKAKNPIKEALKVMLDGRHVLLVGERGERSITNFIGNNGGDTVGAVALDEQGNLVAGTSTGGISG
KLPGRVGDSPIPGAGYYATPRVAVSSTGIGEIILRILPAKEVDMLVSMGFSIEDSVRAVINKITELFGKSNVGLIGIDYK
GYATAYYNTVGMARGVKDKNIVRVFVFEGEI
>Mature_271_residues
MKYTKPVLVVHGGAGDWSKRDYEKGLTEIKKTLERGYEEFKKGSAIEAVVEAIAYMEDSGVFDAGIGSVKNSEGEVEMDA
GIMHGNSWKVGAVASVKAKNPIKEALKVMLDGRHVLLVGERGERSITNFIGNNGGDTVGAVALDEQGNLVAGTSTGGISG
KLPGRVGDSPIPGAGYYATPRVAVSSTGIGEIILRILPAKEVDMLVSMGFSIEDSVRAVINKITELFGKSNVGLIGIDYK
GYATAYYNTVGMARGVKDKNIVRVFVFEGEI

Specific function: Unknown

COG id: COG1446

COG function: function code E; Asparaginase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ntn-hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI145275202, Length=247, Percent_Identity=39.6761133603239, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI145275200, Length=247, Percent_Identity=39.6761133603239, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI285002251, Length=97, Percent_Identity=39.1752577319588, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787050, Length=297, Percent_Identity=36.7003367003367, Blast_Score=149, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17569239, Length=142, Percent_Identity=31.6901408450704, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI18921183, Length=323, Percent_Identity=30.3405572755418, Blast_Score=117, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24652135, Length=120, Percent_Identity=39.1666666666667, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221330102, Length=120, Percent_Identity=39.1666666666667, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24655553, Length=126, Percent_Identity=36.5079365079365, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000246 [H]

Pfam domain/function: PF01112 Asparaginase_2 [H]

EC number: =3.5.1.1 [H]

Molecular weight: Translated: 28724; Mature: 28724

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTKPVLVVHGGAGDWSKRDYEKGLTEIKKTLERGYEEFKKGSAIEAVVEAIAYMEDSG
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
VFDAGIGSVKNSEGEVEMDAGIMHGNSWKVGAVASVKAKNPIKEALKVMLDGRHVLLVGE
CEECCCCCCCCCCCCEEECCEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEC
RGERSITNFIGNNGGDTVGAVALDEQGNLVAGTSTGGISGKLPGRVGDSPIPGAGYYATP
CCCHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
RVAVSSTGIGEIILRILPAKEVDMLVSMGFSIEDSVRAVINKITELFGKSNVGLIGIDYK
CEEEECCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCC
GYATAYYNTVGMARGVKDKNIVRVFVFEGEI
CEEEEHHHHHHHHCCCCCCCEEEEEEEECCC
>Mature Secondary Structure
MKYTKPVLVVHGGAGDWSKRDYEKGLTEIKKTLERGYEEFKKGSAIEAVVEAIAYMEDSG
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
VFDAGIGSVKNSEGEVEMDAGIMHGNSWKVGAVASVKAKNPIKEALKVMLDGRHVLLVGE
CEECCCCCCCCCCCCEEECCEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEC
RGERSITNFIGNNGGDTVGAVALDEQGNLVAGTSTGGISGKLPGRVGDSPIPGAGYYATP
CCCHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
RVAVSSTGIGEIILRILPAKEVDMLVSMGFSIEDSVRAVINKITELFGKSNVGLIGIDYK
CEEEECCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCC
GYATAYYNTVGMARGVKDKNIVRVFVFEGEI
CEEEEHHHHHHHHCCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]