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The map label for this gene is cbiT

Identifier: 15922132

GI number: 15922132

Start: 1833872

End: 1834450

Strand: Reverse

Name: cbiT

Synonym: ST1819

Alternate gene names: 15922132

Gene position: 1834450-1833872 (Counterclockwise)

Preceding gene: 15922134

Following gene: 15922130

Centisome position: 68.07

GC content: 37.65

Gene sequence:

>579_bases
ATGAGACTACCCGGAATACCGGATGAGGAATTTATAAGGGTTGAAAAGATACCGATGACAAAGGAGGAAATAAGAGTTTT
AGCTCTTTCAAAGGCAAGGCTATTTGATGGTGCTAAATTTATTGACATAGGTAGTGGGACTGGAAGCGTTACTGTTGAGG
CTGGCTTAGTAGTCGGGGAAAAAGGTAAGGTTTGGGCTATTGAAAAAGATAAAGATGCTGTAGAACTTACCAAAAAGAAT
GTGGAAAAATTCAAACTTAATAATGTAGTAATCATTGAGGGAGAAGCTCCTGAAGCTTTGGATCACGTAGATAGTGAAGT
TGACGCAATATTTATTGGGGGTACTGAGAGACTTGAGGAAATCCTTCTCTCTAGCGATAAAAAGTTGAAGAACGGTGGAA
GAATTGTTATTGATGCTATCCTTTTAGAAACCGTTAATAAGGCTCTATCAACTCTTAATCAAATGGGATATAAGACTGAT
GTTATAGAAGTCATTATAGCTAAAGGTATGAAGACAAGTAAGGGCTATGCTATGATTTCTCGTAATCCGATCTTTATCGT
TTACGGTGAGAAACCATGA

Upstream 100 bases:

>100_bases
GAGTTCTTCAGAGGTTAAGGAAGATTGTGAAAAATGATGTGAAATTAGGTGTAGTTATTATTTCTGAAGAAGGAGAAGTT
TTAGCTGAGGAGGGTGAGTT

Downstream 100 bases:

>100_bases
GTGAACTTTATGTTATTGGTTTAGGTCCCGGAGATCCTGAGCTAATAACAGTTAAGGGAATGAAGATTTTATCAATTGCT
GATGTTATTTTTGTTCCCTA

Product: cobalt-precorrin-6Y C(15)-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MRLPGIPDEEFIRVEKIPMTKEEIRVLALSKARLFDGAKFIDIGSGTGSVTVEAGLVVGEKGKVWAIEKDKDAVELTKKN
VEKFKLNNVVIIEGEAPEALDHVDSEVDAIFIGGTERLEEILLSSDKKLKNGGRIVIDAILLETVNKALSTLNQMGYKTD
VIEVIIAKGMKTSKGYAMISRNPIFIVYGEKP

Sequences:

>Translated_192_residues
MRLPGIPDEEFIRVEKIPMTKEEIRVLALSKARLFDGAKFIDIGSGTGSVTVEAGLVVGEKGKVWAIEKDKDAVELTKKN
VEKFKLNNVVIIEGEAPEALDHVDSEVDAIFIGGTERLEEILLSSDKKLKNGGRIVIDAILLETVNKALSTLNQMGYKTD
VIEVIIAKGMKTSKGYAMISRNPIFIVYGEKP
>Mature_192_residues
MRLPGIPDEEFIRVEKIPMTKEEIRVLALSKARLFDGAKFIDIGSGTGSVTVEAGLVVGEKGKVWAIEKDKDAVELTKKN
VEKFKLNNVVIIEGEAPEALDHVDSEVDAIFIGGTERLEEILLSSDKKLKNGGRIVIDAILLETVNKALSTLNQMGYKTD
VIEVIIAKGMKTSKGYAMISRNPIFIVYGEKP

Specific function: Probably catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W. Methylation of C-15 would probably be followed by a spontaneous decarboxylation of C-12

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Archaeal-type CbiT family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBIT_SULTO (Q96ZL5)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_377801.1
- ProteinModelPortal:   Q96ZL5
- SMR:   Q96ZL5
- GeneID:   1459875
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST1819
- NMPDR:   fig|273063.1.peg.1969
- HOGENOM:   HBG553505
- OMA:   RNIEVVQ
- ProtClustDB:   PRK00377
- BioCyc:   STOK273063:ST1819-MONOMER
- HAMAP:   MF_00786
- InterPro:   IPR014008
- InterPro:   IPR000682
- PANTHER:   PTHR11579
- TIGRFAMs:   TIGR02469

Pfam domain/function: PF01135 PCMT

EC number: 1.-.-.-

Molecular weight: Translated: 21072; Mature: 21072

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: BINDING 20-20 BINDING 68-68 BINDING 96-96

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPGIPDEEFIRVEKIPMTKEEIRVLALSKARLFDGAKFIDIGSGTGSVTVEAGLVVGE
CCCCCCCCHHHEEEECCCCCHHHHEEEEEHHHHHCCCCEEEEECCCCCEEEEEEEEEECC
KGKVWAIEKDKDAVELTKKNVEKFKLNNVVIIEGEAPEALDHVDSEVDAIFIGGTERLEE
CCCEEEEECCCCHHHHHHHHHHHEEECCEEEEECCCCHHHHHCCCCCCEEEECCHHHHHH
ILLSSDKKLKNGGRIVIDAILLETVNKALSTLNQMGYKTDVIEVIIAKGMKTSKGYAMIS
HHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEE
RNPIFIVYGEKP
CCCEEEEECCCC
>Mature Secondary Structure
MRLPGIPDEEFIRVEKIPMTKEEIRVLALSKARLFDGAKFIDIGSGTGSVTVEAGLVVGE
CCCCCCCCHHHEEEECCCCCHHHHEEEEEHHHHHCCCCEEEEECCCCCEEEEEEEEEECC
KGKVWAIEKDKDAVELTKKNVEKFKLNNVVIIEGEAPEALDHVDSEVDAIFIGGTERLEE
CCCEEEEECCCCHHHHHHHHHHHEEECCEEEEECCCCHHHHHCCCCCCEEEECCHHHHHH
ILLSSDKKLKNGGRIVIDAILLETVNKALSTLNQMGYKTDVIEVIIAKGMKTSKGYAMIS
HHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEE
RNPIFIVYGEKP
CCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479