Click here to switch to the map view.

The map label for this gene is cbiL [H]

Identifier: 15922130

GI number: 15922130

Start: 1833207

End: 1833875

Strand: Reverse

Name: cbiL [H]

Synonym: ST1817

Alternate gene names: 15922130

Gene position: 1833875-1833207 (Counterclockwise)

Preceding gene: 15922132

Following gene: 15922129

Centisome position: 68.05

GC content: 34.08

Gene sequence:

>669_bases
ATGAGTGAACTTTATGTTATTGGTTTAGGTCCCGGAGATCCTGAGCTAATAACAGTTAAGGGAATGAAGATTTTATCAAT
TGCTGATGTTATTTTTGTTCCCTATTCTACTGGAACCAATAGGAGTTTATCTTACAATATTATTCAAGCTTATGGGAAAA
AAGACGCTAAAATAGTAACGCTAGGATTTCCAATGGCTAAAGAGGTAGACGAAAAAGAGCTTGAAAGAATTGGGAGAACA
ATTTGTGAAGAGAAAGGTAAAGTTTCAGCCTTTATTACTTTAGGTGATCCTACACTATATTCCACGTTTTTCAGAGTGAA
AAAATTCCTTTCTTGTTTTGATAAAATAGAATTAATTCCCGGTGTTAGTTCCGTTACTTCGTGTGCTTCTAAACTTAAAC
TCTCTTTAGCTTTAGGTGATGATGCTATCTTAATAGTACCTTCAAGTAGAATTTCTCTCATACAAGAAGTAAAAAATAAG
GTGGAAAGTATCGTAGTGATTAAAGGAAATGAGAACCTTGATAAAATAGCAGAGATTTTGAAGGAAGGGTATGAGCTTTT
TTATGCGAGAAGGTGTTATTTAGAAGGGGAGAAAATTGTTCCCTGGGATGGTACTTTTGATAGAGACTATTTCTCAATGT
TAATAGGGGTGAAAAAGGTTGAAAGGTAA

Upstream 100 bases:

>100_bases
CTGATGTTATAGAAGTCATTATAGCTAAAGGTATGAAGACAAGTAAGGGCTATGCTATGATTTCTCGTAATCCGATCTTT
ATCGTTTACGGTGAGAAACC

Downstream 100 bases:

>100_bases
AGTAGTCTTTATTGGTGCTGGTCCTGGAGATCCAGAATTAATAACTGTCAAGGCAAAAAATTACATTGAAGACGCAGATG
TAATTTTGTATGCAGGATCA

Product: cobalt-precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MSELYVIGLGPGDPELITVKGMKILSIADVIFVPYSTGTNRSLSYNIIQAYGKKDAKIVTLGFPMAKEVDEKELERIGRT
ICEEKGKVSAFITLGDPTLYSTFFRVKKFLSCFDKIELIPGVSSVTSCASKLKLSLALGDDAILIVPSSRISLIQEVKNK
VESIVVIKGNENLDKIAEILKEGYELFYARRCYLEGEKIVPWDGTFDRDYFSMLIGVKKVER

Sequences:

>Translated_222_residues
MSELYVIGLGPGDPELITVKGMKILSIADVIFVPYSTGTNRSLSYNIIQAYGKKDAKIVTLGFPMAKEVDEKELERIGRT
ICEEKGKVSAFITLGDPTLYSTFFRVKKFLSCFDKIELIPGVSSVTSCASKLKLSLALGDDAILIVPSSRISLIQEVKNK
VESIVVIKGNENLDKIAEILKEGYELFYARRCYLEGEKIVPWDGTFDRDYFSMLIGVKKVER
>Mature_221_residues
SELYVIGLGPGDPELITVKGMKILSIADVIFVPYSTGTNRSLSYNIIQAYGKKDAKIVTLGFPMAKEVDEKELERIGRTI
CEEKGKVSAFITLGDPTLYSTFFRVKKFLSCFDKIELIPGVSSVTSCASKLKLSLALGDDAILIVPSSRISLIQEVKNKV
ESIVVIKGNENLDKIAEILKEGYELFYARRCYLEGEKIVPWDGTFDRDYFSMLIGVKKVER

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 24752; Mature: 24621

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00839 SUMT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELYVIGLGPGDPELITVKGMKILSIADVIFVPYSTGTNRSLSYNIIQAYGKKDAKIVT
CCCEEEEEECCCCCCEEEECCEEEEEEEEEEEEECCCCCCCCEEHHHHHHCCCCCCEEEE
LGFPMAKEVDEKELERIGRTICEEKGKVSAFITLGDPTLYSTFFRVKKFLSCFDKIELIP
ECCCCHHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
GVSSVTSCASKLKLSLALGDDAILIVPSSRISLIQEVKNKVESIVVIKGNENLDKIAEIL
CHHHHHHHHHHHEEEEEECCCEEEEECCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHH
KEGYELFYARRCYLEGEKIVPWDGTFDRDYFSMLIGVKKVER
HHHHHHHHHHHEEECCCEEECCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SELYVIGLGPGDPELITVKGMKILSIADVIFVPYSTGTNRSLSYNIIQAYGKKDAKIVT
CCEEEEEECCCCCCEEEECCEEEEEEEEEEEEECCCCCCCCEEHHHHHHCCCCCCEEEE
LGFPMAKEVDEKELERIGRTICEEKGKVSAFITLGDPTLYSTFFRVKKFLSCFDKIELIP
ECCCCHHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
GVSSVTSCASKLKLSLALGDDAILIVPSSRISLIQEVKNKVESIVVIKGNENLDKIAEIL
CHHHHHHHHHHHEEEEEECCCEEEEECCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHH
KEGYELFYARRCYLEGEKIVPWDGTFDRDYFSMLIGVKKVER
HHHHHHHHHHHEEECCCEEECCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]