Click here to switch to the map view.

The map label for this gene is 15922114

Identifier: 15922114

GI number: 15922114

Start: 1817396

End: 1818505

Strand: Reverse

Name: 15922114

Synonym: ST1800

Alternate gene names: NA

Gene position: 1818505-1817396 (Counterclockwise)

Preceding gene: 15922116

Following gene: 15922113

Centisome position: 67.48

GC content: 36.76

Gene sequence:

>1110_bases
ATGAAAGTAGCTATAGTAGGTATAGGTTGGTATGGTTTCAGACCTAACACTAAGGATGTATCATTTAGAGAAATGATGTT
TGAGGCCGCCGTTAGAGCTTATGAAGACTCTGGAAATATAAATCCTAGAACTGATGTAGATACTTTTATTTCATGCCAAG
AAGACTTTTGGGAAGGAATTGCAATAACTGACGAATTTGCCCCAGACCCTATTGGTGGTGCTATGAGACCTACAATGACT
GTGACAGGTGATGGATTACAAGGAATCCTTCATGGAGTTATGCATATTAAATCTGGATTAGCTAATATAACTGTAGTAGA
ATCTCACGCAAAACCTAGTGACATTCTAACAATTAGAGATATAATAGAATTCGCCTTCGACCCAATGTATAGGATTGGAG
CAAAGAACATTCATTTTCTTGCCGGCTTAGAGGCGTTAAAGTTTATGAAATTAAGAAACGCAACAAGAGAAGACTTTGCT
AAAGTTATTGTAAAGAATAAGCGTAATGGTTTGAAGAACCCGAGAGCATCTTATGCATCTAATATCAGCTTAGAAGATAT
ATTGGAGAGAGAATATACAATATACCCCTTAACGGATTTAGATATTTCACGCTTTGTGGATGCAGCAATTGTTGTTGTGC
TAGCAAGTGAAGAGATTGCACGTAAGTATACTGATACTCCAATATGGATTGATGGTATATACTCTGCTACTGATTCTACA
ATAGAACTTTCAGAATTGGGAGAGGCAAGATATATGAAAATTGCCTCAAAGGAAGCTTATAACATGGCGAAAGTGAATAA
AAGGGAAATAAAAGCTGCTTTTGTTGACGATACTTATAGTTATAAAGAGCTTCAGCATATTGAAGGGCTAAGTTTAAGTG
ATAACGCTGTAAAAGATTTACGAGAAGGTGAATTTGAAAGAGGAGGCAAGATTGAAGTTAATCCTTTAGGTGGTCATCTG
GCTAAGGGTAGACCATTAGAAGTTAGTGGATTATCATTATTACTAGATGCTGTTGAATATTTGAGGCAAGGAGTTGTTGA
TAAAGCTGTAGTAGCAAGTTGGAGAGGAATTCCTACTTTTACAGGTGTTGTTGGGGTGGTGAGTAGATAA

Upstream 100 bases:

>100_bases
AGCAATATATTAATAATTAAATCAATTTAAGTAAAATGAAATATTCACTATATAAGAAAAACTTAATAGTTTTTGAGAGA
TATAATGATTGTGATTTTTT

Downstream 100 bases:

>100_bases
TGAAGACGAATTTATATTTTAGAAGGGTAGCTGTAATAGGTGCCGGATTAACGTTATTTAGAAGGAGAATGTTAGAGACT
CCACAAGAATTGGCGTGGGA

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MKVAIVGIGWYGFRPNTKDVSFREMMFEAAVRAYEDSGNINPRTDVDTFISCQEDFWEGIAITDEFAPDPIGGAMRPTMT
VTGDGLQGILHGVMHIKSGLANITVVESHAKPSDILTIRDIIEFAFDPMYRIGAKNIHFLAGLEALKFMKLRNATREDFA
KVIVKNKRNGLKNPRASYASNISLEDILEREYTIYPLTDLDISRFVDAAIVVVLASEEIARKYTDTPIWIDGIYSATDST
IELSELGEARYMKIASKEAYNMAKVNKREIKAAFVDDTYSYKELQHIEGLSLSDNAVKDLREGEFERGGKIEVNPLGGHL
AKGRPLEVSGLSLLLDAVEYLRQGVVDKAVVASWRGIPTFTGVVGVVSR

Sequences:

>Translated_369_residues
MKVAIVGIGWYGFRPNTKDVSFREMMFEAAVRAYEDSGNINPRTDVDTFISCQEDFWEGIAITDEFAPDPIGGAMRPTMT
VTGDGLQGILHGVMHIKSGLANITVVESHAKPSDILTIRDIIEFAFDPMYRIGAKNIHFLAGLEALKFMKLRNATREDFA
KVIVKNKRNGLKNPRASYASNISLEDILEREYTIYPLTDLDISRFVDAAIVVVLASEEIARKYTDTPIWIDGIYSATDST
IELSELGEARYMKIASKEAYNMAKVNKREIKAAFVDDTYSYKELQHIEGLSLSDNAVKDLREGEFERGGKIEVNPLGGHL
AKGRPLEVSGLSLLLDAVEYLRQGVVDKAVVASWRGIPTFTGVVGVVSR
>Mature_369_residues
MKVAIVGIGWYGFRPNTKDVSFREMMFEAAVRAYEDSGNINPRTDVDTFISCQEDFWEGIAITDEFAPDPIGGAMRPTMT
VTGDGLQGILHGVMHIKSGLANITVVESHAKPSDILTIRDIIEFAFDPMYRIGAKNIHFLAGLEALKFMKLRNATREDFA
KVIVKNKRNGLKNPRASYASNISLEDILEREYTIYPLTDLDISRFVDAAIVVVLASEEIARKYTDTPIWIDGIYSATDST
IELSELGEARYMKIASKEAYNMAKVNKREIKAAFVDDTYSYKELQHIEGLSLSDNAVKDLREGEFERGGKIEVNPLGGHL
AKGRPLEVSGLSLLLDAVEYLRQGVVDKAVVASWRGIPTFTGVVGVVSR

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Drosophila melanogaster, GI24585051, Length=247, Percent_Identity=27.1255060728745, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19921506, Length=250, Percent_Identity=27.2, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 40952; Mature: 40952

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAIVGIGWYGFRPNTKDVSFREMMFEAAVRAYEDSGNINPRTDVDTFISCQEDFWEGI
CEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHCCCE
AITDEFAPDPIGGAMRPTMTVTGDGLQGILHGVMHIKSGLANITVVESHAKPSDILTIRD
EEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
IIEFAFDPMYRIGAKNIHFLAGLEALKFMKLRNATREDFAKVIVKNKRNGLKNPRASYAS
HHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHC
NISLEDILEREYTIYPLTDLDISRFVDAAIVVVLASEEIARKYTDTPIWIDGIYSATDST
CCCHHHHHHCCEEEEEECCCCHHHHHHHHHEEEECCHHHHHHHCCCCEEEEEEECCCCCE
IELSELGEARYMKIASKEAYNMAKVNKREIKAAFVDDTYSYKELQHIEGLSLSDNAVKDL
EEHHHCCCHHHHHHHHHHHHHHHHCCHHHHEEEEECCCCCHHHHHHHCCCCCCHHHHHHH
REGEFERGGKIEVNPLGGHLAKGRPLEVSGLSLLLDAVEYLRQGVVDKAVVASWRGIPTF
HCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHH
TGVVGVVSR
HHHHHHCCC
>Mature Secondary Structure
MKVAIVGIGWYGFRPNTKDVSFREMMFEAAVRAYEDSGNINPRTDVDTFISCQEDFWEGI
CEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHCCCE
AITDEFAPDPIGGAMRPTMTVTGDGLQGILHGVMHIKSGLANITVVESHAKPSDILTIRD
EEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
IIEFAFDPMYRIGAKNIHFLAGLEALKFMKLRNATREDFAKVIVKNKRNGLKNPRASYAS
HHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHC
NISLEDILEREYTIYPLTDLDISRFVDAAIVVVLASEEIARKYTDTPIWIDGIYSATDST
CCCHHHHHHCCEEEEEECCCCHHHHHHHHHEEEECCHHHHHHHCCCCEEEEEEECCCCCE
IELSELGEARYMKIASKEAYNMAKVNKREIKAAFVDDTYSYKELQHIEGLSLSDNAVKDL
EEHHHCCCHHHHHHHHHHHHHHHHCCHHHHEEEEECCCCCHHHHHHHCCCCCCHHHHHHH
REGEFERGGKIEVNPLGGHLAKGRPLEVSGLSLLLDAVEYLRQGVVDKAVVASWRGIPTF
HCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHH
TGVVGVVSR
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]