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The map label for this gene is dppD [H]

Identifier: 15921950

GI number: 15921950

Start: 1638541

End: 1639380

Strand: Reverse

Name: dppD [H]

Synonym: ST1647

Alternate gene names: 15921950

Gene position: 1639380-1638541 (Counterclockwise)

Preceding gene: 15921951

Following gene: 15921949

Centisome position: 60.84

GC content: 29.76

Gene sequence:

>840_bases
ATGTTAAAGTACGAATGTTTAAGCGTAAAAGGAAAGTTAAACTGTTTCTCACTTGAGATTAAAGAAGATTCTGGAATATT
AGGACAAAGGGATAGTGGTAAGGAAGAAATAATAAATGCTACTTTTAAGTTGACAAAAGATTTTAGTGGACGAATTCTCT
TAGATGACATAGATATTACAAGATACAATGAAGAGATATATTGGACTAAAATTTCTGTTATATTTTATGATCCAATGAAA
TTATTTAATCCGATCTACGATATAGCATCACACTTTATTGAAATTGGGATAAGCCATGGAATTGAAAATGAAGAGGCTAT
TTTAGAGACTGCTGAAGAGATTTTAAAAATATTGGGCATGAAGAAAGAGGTACTTTTCTCTTATCCGAATCAGTTAAAAC
CATTAGAATTAAAGAAGACAGCATTAGCATTAGCTTCATTTCTTGAACCAGAATATATCTTCATAGATGATATTGAATAT
AATTTAAGCACTTTAGAAATAGAACTTCTAATTAACTCTATTTTGGATTTAAAAGAGACATTCAATATGAAACTTATTGT
TTTTGATAACGATCCAGCAGTTATATCTAGATTAACTGACTATGTTGTAGTTCTTTATAGGGGTGAAATAGTAGAAGAGG
GATACAATGTGATTGAATATCCTTATCATCCGTATACAATAGATTTAATTAGAGGTGAATTGAAAGGAAAAAACCTAATT
GGGAAAGGATGTATATATAGTGAAAATTGTAGGTTTTCAACTCTCAATTGTAAAAACATTACTCCAAAGCTAGTTGATCT
AGGAGGTAGAAGGTTAAAATGTTTGGGATTCCCATGGTAA

Upstream 100 bases:

>100_bases
TAATTCCAGACTGGTGGCTGTTTCTTATACCAGCAATATTTAGGGGTATTATACTTATCCTACTTCAATTATTAGCCGAT
GAAATAAGGAGGATTTAAAA

Downstream 100 bases:

>100_bases
TACAAAATATATCTGGGAAGTTCATTTCAAACATAGATTTAGAAATACATAAAATAAGTTGCATAATTGGGAATTCTGGA
AAGGATAAAGAGGAAATAGA

Product: peptide transporter ATP-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MLKYECLSVKGKLNCFSLEIKEDSGILGQRDSGKEEIINATFKLTKDFSGRILLDDIDITRYNEEIYWTKISVIFYDPMK
LFNPIYDIASHFIEIGISHGIENEEAILETAEEILKILGMKKEVLFSYPNQLKPLELKKTALALASFLEPEYIFIDDIEY
NLSTLEIELLINSILDLKETFNMKLIVFDNDPAVISRLTDYVVVLYRGEIVEEGYNVIEYPYHPYTIDLIRGELKGKNLI
GKGCIYSENCRFSTLNCKNITPKLVDLGGRRLKCLGFPW

Sequences:

>Translated_279_residues
MLKYECLSVKGKLNCFSLEIKEDSGILGQRDSGKEEIINATFKLTKDFSGRILLDDIDITRYNEEIYWTKISVIFYDPMK
LFNPIYDIASHFIEIGISHGIENEEAILETAEEILKILGMKKEVLFSYPNQLKPLELKKTALALASFLEPEYIFIDDIEY
NLSTLEIELLINSILDLKETFNMKLIVFDNDPAVISRLTDYVVVLYRGEIVEEGYNVIEYPYHPYTIDLIRGELKGKNLI
GKGCIYSENCRFSTLNCKNITPKLVDLGGRRLKCLGFPW
>Mature_279_residues
MLKYECLSVKGKLNCFSLEIKEDSGILGQRDSGKEEIINATFKLTKDFSGRILLDDIDITRYNEEIYWTKISVIFYDPMK
LFNPIYDIASHFIEIGISHGIENEEAILETAEEILKILGMKKEVLFSYPNQLKPLELKKTALALASFLEPEYIFIDDIEY
NLSTLEIELLINSILDLKETFNMKLIVFDNDPAVISRLTDYVVVLYRGEIVEEGYNVIEYPYHPYTIDLIRGELKGKNLI
GKGCIYSENCRFSTLNCKNITPKLVDLGGRRLKCLGFPW

Specific function: Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system [H]

COG id: COG0444

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1789963, Length=289, Percent_Identity=26.2975778546713, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787759, Length=295, Percent_Identity=26.1016949152542, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789962, Length=283, Percent_Identity=21.9081272084806, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787758, Length=286, Percent_Identity=24.1258741258741, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI48994883, Length=290, Percent_Identity=24.1379310344828, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI145693107, Length=245, Percent_Identity=24.8979591836735, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787500, Length=282, Percent_Identity=23.4042553191489, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787547, Length=225, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788506, Length=250, Percent_Identity=25.6, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787548, Length=239, Percent_Identity=24.2677824267782, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789890, Length=222, Percent_Identity=26.1261261261261, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 32126; Mature: 32126

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKYECLSVKGKLNCFSLEIKEDSGILGQRDSGKEEIINATFKLTKDFSGRILLDDIDIT
CCEEEEEEECCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHEEEECCCCCEEEEEECEEE
RYNEEIYWTKISVIFYDPMKLFNPIYDIASHFIEIGISHGIENEEAILETAEEILKILGM
EECCEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
KKEVLFSYPNQLKPLELKKTALALASFLEPEYIFIDDIEYNLSTLEIELLINSILDLKET
CHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHH
FNMKLIVFDNDPAVISRLTDYVVVLYRGEIVEEGYNVIEYPYHPYTIDLIRGELKGKNLI
CCEEEEEECCCHHHHHHHHHHEEEEEECHHHHCCCCEEECCCCCEEEEEEECCCCCCCEE
GKGCIYSENCRFSTLNCKNITPKLVDLGGRRLKCLGFPW
ECCCEEECCCCEEEEECCCCCHHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MLKYECLSVKGKLNCFSLEIKEDSGILGQRDSGKEEIINATFKLTKDFSGRILLDDIDIT
CCEEEEEEECCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHEEEECCCCCEEEEEECEEE
RYNEEIYWTKISVIFYDPMKLFNPIYDIASHFIEIGISHGIENEEAILETAEEILKILGM
EECCEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
KKEVLFSYPNQLKPLELKKTALALASFLEPEYIFIDDIEYNLSTLEIELLINSILDLKET
CHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHH
FNMKLIVFDNDPAVISRLTDYVVVLYRGEIVEEGYNVIEYPYHPYTIDLIRGELKGKNLI
CCEEEEEECCCHHHHHHHHHHEEEEEECHHHHCCCCEEECCCCCEEEEEEECCCCCCCEE
GKGCIYSENCRFSTLNCKNITPKLVDLGGRRLKCLGFPW
ECCCEEECCCCEEEEECCCCCHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]