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The map label for this gene is pyrF

Identifier: 15921775

GI number: 15921775

Start: 1480267

End: 1480908

Strand: Direct

Name: pyrF

Synonym: ST1482

Alternate gene names: 15921775

Gene position: 1480267-1480908 (Clockwise)

Preceding gene: 15921774

Following gene: 15921776

Centisome position: 54.93

GC content: 29.91

Gene sequence:

>642_bases
GTGATTCTTTCGTTAGATAGACAAATACCTCTTTCTACTCTATCAGAAATAAATAAATATATACATAAGGTTAAAATAGG
CTATCCATTAATTCTTGAAAACATAGAATATCTAGATGATATAGTAAAACTCCACTGGGATGAAATAATATTTGATTTAA
AACTTGCTGATATAGATAATACTATGGTTCTTATAGTATCTAAATTTATTAATTACGCAGATTCTTTCATTGCACATTCT
TTCATAGGCATTGAAGGCGCCTTAGATAAATTATCAGAATTTTTGAAAAATCAGAATAAGTCCTTATATCTTGTCTTATC
AATGTCTCATAAAGGCTGGAATGACGAATTTTACCCTTATTTAAAAAATATAGCTAAGACAATAGATCCTAAAGGATTTG
TGGTTGGTGCAACTAGACCTAACATGATTAGAATTGTAAGGAATGATTTTAGGGATAAAATAATCATTTCTCCTGGAGTT
GGCGCTCAAGGGGCTATGATTGGTGATGCTATCTGTAATGGAGCTGATTATGAAATAATAGGAAGAAGTATATATGAGTC
TAAAGACCCTGTAACTGAAACAAAGAAAATAATTGAGACTCAAGAAGTGAAAATTAATGAGTGCAAAAGAACAGAAAATT
AA

Upstream 100 bases:

>100_bases
AAAATTAGGGAGATTTTGGAGTATTTGCTAAATTCTAGTTTAATTTCGGATAACGATAAAAATAATATAAAAGAATATTT
GGTGAAAAATATTGAATAGA

Downstream 100 bases:

>100_bases
CCTAGATGAATTAAGCGAAAAACTTTCGAAAATAGCAGAATTGATAAATAAAGCTGAAGAGATTCACGAAGAATTTAATG
AAGTTCCCACTACAGATTTC

Product: orotidine-5'-monophosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MILSLDRQIPLSTLSEINKYIHKVKIGYPLILENIEYLDDIVKLHWDEIIFDLKLADIDNTMVLIVSKFINYADSFIAHS
FIGIEGALDKLSEFLKNQNKSLYLVLSMSHKGWNDEFYPYLKNIAKTIDPKGFVVGATRPNMIRIVRNDFRDKIIISPGV
GAQGAMIGDAICNGADYEIIGRSIYESKDPVTETKKIIETQEVKINECKRTEN

Sequences:

>Translated_213_residues
MILSLDRQIPLSTLSEINKYIHKVKIGYPLILENIEYLDDIVKLHWDEIIFDLKLADIDNTMVLIVSKFINYADSFIAHS
FIGIEGALDKLSEFLKNQNKSLYLVLSMSHKGWNDEFYPYLKNIAKTIDPKGFVVGATRPNMIRIVRNDFRDKIIISPGV
GAQGAMIGDAICNGADYEIIGRSIYESKDPVTETKKIIETQEVKINECKRTEN
>Mature_213_residues
MILSLDRQIPLSTLSEINKYIHKVKIGYPLILENIEYLDDIVKLHWDEIIFDLKLADIDNTMVLIVSKFINYADSFIAHS
FIGIEGALDKLSEFLKNQNKSLYLVLSMSHKGWNDEFYPYLKNIAKTIDPKGFVVGATRPNMIRIVRNDFRDKIIISPGV
GAQGAMIGDAICNGADYEIIGRSIYESKDPVTETKKIIETQEVKINECKRTEN

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRF_SULTO (Q970X0)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_377444.1
- ProteinModelPortal:   Q970X0
- SMR:   Q970X0
- GeneID:   1459517
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST1482
- NMPDR:   fig|273063.1.peg.1612
- HOGENOM:   HBG625253
- OMA:   ICNGADY
- ProtClustDB:   CLSK802793
- BioCyc:   STOK273063:ST1482-MONOMER
- BRENDA:   4.1.1.23
- HAMAP:   MF_01200_A
- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00934
- TIGRFAMs:   TIGR01740

Pfam domain/function: PF00215 OMPdecase; SSF51366 RibP_bind_barrel

EC number: =4.1.1.23

Molecular weight: Translated: 24272; Mature: 24272

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00156 OMPDECASE

Important sites: ACT_SITE 54-54 BINDING 6-6 BINDING 25-25 BINDING 109-109 BINDING 181-181 BINDING 182-182

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSLDRQIPLSTLSEINKYIHKVKIGYPLILENIEYLDDIVKLHWDEIIFDLKLADIDN
CEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
TMVLIVSKFINYADSFIAHSFIGIEGALDKLSEFLKNQNKSLYLVLSMSHKGWNDEFYPY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHH
LKNIAKTIDPKGFVVGATRPNMIRIVRNDFRDKIIISPGVGAQGAMIGDAICNGADYEII
HHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCEEEECCCCCCCCCCHHHHHCCCCCHHHH
GRSIYESKDPVTETKKIIETQEVKINECKRTEN
HHHHHCCCCCHHHHHHHHHHHCCHHHHHCCCCC
>Mature Secondary Structure
MILSLDRQIPLSTLSEINKYIHKVKIGYPLILENIEYLDDIVKLHWDEIIFDLKLADIDN
CEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
TMVLIVSKFINYADSFIAHSFIGIEGALDKLSEFLKNQNKSLYLVLSMSHKGWNDEFYPY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHH
LKNIAKTIDPKGFVVGATRPNMIRIVRNDFRDKIIISPGVGAQGAMIGDAICNGADYEII
HHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCEEEECCCCCCCCCCHHHHHCCCCCHHHH
GRSIYESKDPVTETKKIIETQEVKINECKRTEN
HHHHHCCCCCHHHHHHHHHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479