Click here to switch to the map view.

The map label for this gene is pdxS

Identifier: 15921732

GI number: 15921732

Start: 1446232

End: 1447242

Strand: Direct

Name: pdxS

Synonym: ST1441

Alternate gene names: 15921732

Gene position: 1446232-1447242 (Clockwise)

Preceding gene: 161751093

Following gene: 15921733

Centisome position: 53.67

GC content: 37.78

Gene sequence:

>1011_bases
ATGAGATTATATGAACTAAGTTTTTATGAGGTCGAGCAATTCTTTTATAAGCTAGCAGAAGTGAGAGATATAATCAAAGA
TCAAGGTTTACTTTCCTTTTTACCACAAAAGTTAGACGCAGAATTAGTCCAGGGTTCTACTATGGTAAAACATGCCTTTC
CAATATTTCAGAAGGGAGGAGTTGTTATGGACGTAACTAATGTTACCCAGGCGGAAATCGCTGAAGATGCTGGAGCTACT
GCTGTAATGGTTTTAGATAAACTACCTTATGACGTAAGAAAAAGTGGTGGTGTAGCAAGGATGGCTGACCCTAAGATAAT
TGAAGAAGTCATGAATTCTATTACAATCCCTGTTATGGCTAAGGTGAGAATAGGACACTATTATGAAGCTAAAATACTGG
AAGCCTTAGGTGTTGATATGATAGATGAGAGTGAAGTACTAACTCCAGCTGATGAGGAACACCATATTAATAAATGGGAA
TTTAAAGTACCTTTTGTAAATGGTGCAAGGAACTTAGGAGAAGCTTTAAGAAGGATAACAGAAGGTGCATCAATGATTAG
AACTAAAGGTGAGGCTGGTACTGGTAATGTAAGTGAAGCTGTTAAACACATGAAGATAATAAATGGTGAAATAAGGTCGT
TGATTTCCATGTCAGAAGAAGATAGAATGAAAAAAGCAAGAGAATATCAAGTTCCATATCAAATAGTTGAGTTAACAGTA
AAGTTAGGAAGATTACCAGTAGTTAATTTCGCTGCTGGAGGTATTGCAACACCAGCAGATGCCGCATTAATGATGTGGTT
AGGTGCCGATGGCATATTTGTAGGTTCTGGTATCTTTAAGAGCCAAGACCCTGATGTTAGAGCGAAGGCTATAGTATTAG
CTACCGCTAACTGGGAAGACCCAGAAATAGTTCTTGAAGCTCAAAAGATGATAAGCGAGAGTAAAAGCATGATGGGAATT
GATATTAAAGCATTGAAGCCAGAGGAATTACTTCAGGTGAGAGGTCAATGA

Upstream 100 bases:

>100_bases
GAATAATTAAGATTAGACCAGAAGAAGAAAGAAAACAAAAAGCAAAACTCTACTAATAAACTTTTTTATGCATTTCATGT
ATATTTTAATTTGACGTCAA

Downstream 100 bases:

>100_bases
AAATTGGAATTGTTGCATATCAAGGTAGCTTTGAAGAACATGCGTTACAGACTAAAAGAGCTTTGGACAATTTGAAAATT
CAAGGAGATATAGTTGCTGT

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MRLYELSFYEVEQFFYKLAEVRDIIKDQGLLSFLPQKLDAELVQGSTMVKHAFPIFQKGGVVMDVTNVTQAEIAEDAGAT
AVMVLDKLPYDVRKSGGVARMADPKIIEEVMNSITIPVMAKVRIGHYYEAKILEALGVDMIDESEVLTPADEEHHINKWE
FKVPFVNGARNLGEALRRITEGASMIRTKGEAGTGNVSEAVKHMKIINGEIRSLISMSEEDRMKKAREYQVPYQIVELTV
KLGRLPVVNFAAGGIATPADAALMMWLGADGIFVGSGIFKSQDPDVRAKAIVLATANWEDPEIVLEAQKMISESKSMMGI
DIKALKPEELLQVRGQ

Sequences:

>Translated_336_residues
MRLYELSFYEVEQFFYKLAEVRDIIKDQGLLSFLPQKLDAELVQGSTMVKHAFPIFQKGGVVMDVTNVTQAEIAEDAGAT
AVMVLDKLPYDVRKSGGVARMADPKIIEEVMNSITIPVMAKVRIGHYYEAKILEALGVDMIDESEVLTPADEEHHINKWE
FKVPFVNGARNLGEALRRITEGASMIRTKGEAGTGNVSEAVKHMKIINGEIRSLISMSEEDRMKKAREYQVPYQIVELTV
KLGRLPVVNFAAGGIATPADAALMMWLGADGIFVGSGIFKSQDPDVRAKAIVLATANWEDPEIVLEAQKMISESKSMMGI
DIKALKPEELLQVRGQ
>Mature_336_residues
MRLYELSFYEVEQFFYKLAEVRDIIKDQGLLSFLPQKLDAELVQGSTMVKHAFPIFQKGGVVMDVTNVTQAEIAEDAGAT
AVMVLDKLPYDVRKSGGVARMADPKIIEEVMNSITIPVMAKVRIGHYYEAKILEALGVDMIDESEVLTPADEEHHINKWE
FKVPFVNGARNLGEALRRITEGASMIRTKGEAGTGNVSEAVKHMKIINGEIRSLISMSEEDRMKKAREYQVPYQIVELTV
KLGRLPVVNFAAGGIATPADAALMMWLGADGIFVGSGIFKSQDPDVRAKAIVLATANWEDPEIVLEAQKMISESKSMMGI
DIKALKPEELLQVRGQ

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323743, Length=278, Percent_Identity=58.6330935251799, Blast_Score=320, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6321049, Length=279, Percent_Identity=58.4229390681004, Blast_Score=315, Evalue=7e-87,
Organism=Saccharomyces cerevisiae, GI6323996, Length=279, Percent_Identity=58.4229390681004, Blast_Score=314, Evalue=1e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXS_SULTO (Q971B3)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_377401.1
- ProteinModelPortal:   Q971B3
- SMR:   Q971B3
- GeneID:   1459474
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST1441
- NMPDR:   fig|273063.1.peg.1569
- HOGENOM:   HBG292342
- OMA:   ARMSDPD
- ProtClustDB:   PRK04180
- BioCyc:   STOK273063:ST1441-MONOMER
- HAMAP:   MF_01824
- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF029271
- TIGRFAMs:   TIGR00343

Pfam domain/function: PF01680 SOR_SNZ; SSF51366 RibP_bind_barrel

EC number: NA

Molecular weight: Translated: 37187; Mature: 37187

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS01235 PDXS_SNZ_1; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLYELSFYEVEQFFYKLAEVRDIIKDQGLLSFLPQKLDAELVQGSTMVKHAFPIFQKGG
CEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
VVMDVTNVTQAEIAEDAGATAVMVLDKLPYDVRKSGGVARMADPKIIEEVMNSITIPVMA
EEEEECCCHHHHHHHHCCCEEEEEEHHCCHHHHHCCCEEECCCHHHHHHHHHHCCCCEEE
KVRIGHYYEAKILEALGVDMIDESEVLTPADEEHHINKWEFKVPFVNGARNLGEALRRIT
EEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
EGASMIRTKGEAGTGNVSEAVKHMKIINGEIRSLISMSEEDRMKKAREYQVPYQIVELTV
HCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHH
KLGRLPVVNFAAGGIATPADAALMMWLGADGIFVGSGIFKSQDPDVRAKAIVLATANWED
HHCCCCEEEECCCCCCCCHHHHHHHEECCCCEEEECCCCCCCCCCCEEEEEEEEECCCCC
PEIVLEAQKMISESKSMMGIDIKALKPEELLQVRGQ
CHHHHHHHHHHHHCCHHCCCEEEECCHHHHHHCCCC
>Mature Secondary Structure
MRLYELSFYEVEQFFYKLAEVRDIIKDQGLLSFLPQKLDAELVQGSTMVKHAFPIFQKGG
CEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
VVMDVTNVTQAEIAEDAGATAVMVLDKLPYDVRKSGGVARMADPKIIEEVMNSITIPVMA
EEEEECCCHHHHHHHHCCCEEEEEEHHCCHHHHHCCCEEECCCHHHHHHHHHHCCCCEEE
KVRIGHYYEAKILEALGVDMIDESEVLTPADEEHHINKWEFKVPFVNGARNLGEALRRIT
EEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
EGASMIRTKGEAGTGNVSEAVKHMKIINGEIRSLISMSEEDRMKKAREYQVPYQIVELTV
HCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHH
KLGRLPVVNFAAGGIATPADAALMMWLGADGIFVGSGIFKSQDPDVRAKAIVLATANWED
HHCCCCEEEECCCCCCCCHHHHHHHEECCCCEEEECCCCCCCCCCCEEEEEEEEECCCCC
PEIVLEAQKMISESKSMMGIDIKALKPEELLQVRGQ
CHHHHHHHHHHHHCCHHCCCEEEECCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479