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The map label for this gene is aspC

Identifier: 15921489

GI number: 15921489

Start: 1227651

End: 1228850

Strand: Reverse

Name: aspC

Synonym: ST1225

Alternate gene names: 15921489

Gene position: 1228850-1227651 (Counterclockwise)

Preceding gene: 15921490

Following gene: 15921487

Centisome position: 45.6

GC content: 32.5

Gene sequence:

>1200_bases
ATGCCAGTAGATGATTTTTCCCTTTCGGCAAATAGTATATCAGGAGAATCTACCCTAGTATATCAAGATGTTGCAAGACA
AGTACAGAAGACTAAGGGAATAAGAATCATAAATTTTGGTATAGGACAACCGGATTTGCCTACATTTGCCAGAATAAGAG
AAGCTGCAAAGAAATCATTGGATGAAGGATTTACTGGCTATACATCAGCTTATGGAATTGATGAATTAAGACAAAAGATA
GCAGAGCATTTAAGCAGTAAATATGAGAGTGTGAGAAAGGAAGAAGTTATTGTAACTCCTGGGGCAAAAACGGCACTTTA
CTTAGCCTTTTTATTATACATAAATCCTGGAGACGAAGTTATAATATTTGACCCTTCATTTTACTCTTATGCAGAAGTAG
TAAAGATGTTAGGAGGAGTCCCAGTTTATGTTAAAATGAAGTTTAATGAGAGTACTGGATTTTCTCTTAACTTATCGGAA
TTAGAATCTAAAATAAATAAAAAAACAAAAATGATAGTATTAAATAATCCTCATAATCCAACAGGTATGGTGTTTGATCC
AATAGAAATTGAAAAGCTAATGGAGATTACTAAGGAAAAGAAAGTTCTTCTTCTATCAGATGAAATATATGATTATTTTA
TTTATGAAGGAAAGATGAAGAGTGTACTAGAAGATCCAGATTGGAGAGACTATGTTATTTATGTAAATGGATTCAGTAAA
ACGTTCTCTATGACTGGTTGGAGGTTAGGGTATGTAGTAGCTAAAGAAAAAGTGATTAAGAAAATGGCAGAGATTGCTGC
AAATATTTATACTTGTCCTACTAGTTTTGCTCAGAAAGGTGCATTAGCAGCTTTTGAATCTTTTGATGAAGTTAAGGAAA
TGATATCATTATTTAAAAAGAGAAGGGATATAATGTACGAAGAACTTAAGAAAATAAAAGGAATACAAGTGCATAAAAGT
CAAGGAGCGTTCTACATGTTTCCATTTATTGGCGAGATTCTAAAAAAGGCTAATCTTAGTGTTAAAGACTTTTCGTTAAA
GTTAATTGAGGAAAAAGGAGTAACCACCATACCGGGTGAAGTATTCCCATTAGAAGTTGGTAAAGATTTTGTTAGGCTTA
GTTTTGCTGTAAAAGAAGATGATATAAGAGAAGGTATAAAAAGGATGAAAGAGTTTATTGATATGTTGATGACACCCTGA

Upstream 100 bases:

>100_bases
TATCATAGAATTAAAGAAGTATGGGGCCGATGCTTTTCTCATAGGAACGACTTTAATGAAGGACCCAAACAAAATTAAGG
AACTAATATAATTTTTTCCT

Downstream 100 bases:

>100_bases
TAGTGTGAAAAGATGAACGAAACTCCCATGGGCTGATCTAACTAAGTAGCTCTGCCTTAATTTCTTCTCCTTCCTCGTAT
ACAATTTTTTCTATTTTTAA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MPVDDFSLSANSISGESTLVYQDVARQVQKTKGIRIINFGIGQPDLPTFARIREAAKKSLDEGFTGYTSAYGIDELRQKI
AEHLSSKYESVRKEEVIVTPGAKTALYLAFLLYINPGDEVIIFDPSFYSYAEVVKMLGGVPVYVKMKFNESTGFSLNLSE
LESKINKKTKMIVLNNPHNPTGMVFDPIEIEKLMEITKEKKVLLLSDEIYDYFIYEGKMKSVLEDPDWRDYVIYVNGFSK
TFSMTGWRLGYVVAKEKVIKKMAEIAANIYTCPTSFAQKGALAAFESFDEVKEMISLFKKRRDIMYEELKKIKGIQVHKS
QGAFYMFPFIGEILKKANLSVKDFSLKLIEEKGVTTIPGEVFPLEVGKDFVRLSFAVKEDDIREGIKRMKEFIDMLMTP

Sequences:

>Translated_399_residues
MPVDDFSLSANSISGESTLVYQDVARQVQKTKGIRIINFGIGQPDLPTFARIREAAKKSLDEGFTGYTSAYGIDELRQKI
AEHLSSKYESVRKEEVIVTPGAKTALYLAFLLYINPGDEVIIFDPSFYSYAEVVKMLGGVPVYVKMKFNESTGFSLNLSE
LESKINKKTKMIVLNNPHNPTGMVFDPIEIEKLMEITKEKKVLLLSDEIYDYFIYEGKMKSVLEDPDWRDYVIYVNGFSK
TFSMTGWRLGYVVAKEKVIKKMAEIAANIYTCPTSFAQKGALAAFESFDEVKEMISLFKKRRDIMYEELKKIKGIQVHKS
QGAFYMFPFIGEILKKANLSVKDFSLKLIEEKGVTTIPGEVFPLEVGKDFVRLSFAVKEDDIREGIKRMKEFIDMLMTP
>Mature_398_residues
PVDDFSLSANSISGESTLVYQDVARQVQKTKGIRIINFGIGQPDLPTFARIREAAKKSLDEGFTGYTSAYGIDELRQKIA
EHLSSKYESVRKEEVIVTPGAKTALYLAFLLYINPGDEVIIFDPSFYSYAEVVKMLGGVPVYVKMKFNESTGFSLNLSEL
ESKINKKTKMIVLNNPHNPTGMVFDPIEIEKLMEITKEKKVLLLSDEIYDYFIYEGKMKSVLEDPDWRDYVIYVNGFSKT
FSMTGWRLGYVVAKEKVIKKMAEIAANIYTCPTSFAQKGALAAFESFDEVKEMISLFKKRRDIMYEELKKIKGIQVHKSQ
GAFYMFPFIGEILKKANLSVKDFSLKLIEEKGVTTIPGEVFPLEVGKDFVRLSFAVKEDDIREGIKRMKEFIDMLMTP

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family

Homologues:

Organism=Homo sapiens, GI95147551, Length=393, Percent_Identity=27.4809160305344, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI169881279, Length=393, Percent_Identity=27.4809160305344, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI56713254, Length=265, Percent_Identity=32.0754716981132, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI56713256, Length=265, Percent_Identity=32.0754716981132, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4507369, Length=393, Percent_Identity=24.4274809160305, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI169881281, Length=303, Percent_Identity=26.4026402640264, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI215599424, Length=394, Percent_Identity=23.3502538071066, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI19263340, Length=394, Percent_Identity=23.3502538071066, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1786816, Length=368, Percent_Identity=27.1739130434783, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788722, Length=378, Percent_Identity=28.8359788359788, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788627, Length=346, Percent_Identity=27.1676300578035, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787710, Length=306, Percent_Identity=22.5490196078431, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788332, Length=246, Percent_Identity=24.390243902439, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790797, Length=187, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=257, Percent_Identity=36.1867704280156, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI71994472, Length=257, Percent_Identity=36.5758754863813, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17567369, Length=400, Percent_Identity=29.5, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17567663, Length=377, Percent_Identity=25.4641909814324, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71981209, Length=373, Percent_Identity=24.6648793565684, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322401, Length=409, Percent_Identity=27.6283618581907, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6323118, Length=389, Percent_Identity=28.0205655526992, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320317, Length=355, Percent_Identity=24.5070422535211, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573069, Length=392, Percent_Identity=30.1020408163265, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24646114, Length=392, Percent_Identity=30.1020408163265, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI28573067, Length=392, Percent_Identity=30.1020408163265, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI28573065, Length=392, Percent_Identity=30.1020408163265, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI18859735, Length=380, Percent_Identity=25, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24641770, Length=396, Percent_Identity=24.2424242424242, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641760, Length=396, Percent_Identity=24.2424242424242, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641768, Length=396, Percent_Identity=24.2424242424242, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641766, Length=396, Percent_Identity=24.2424242424242, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641764, Length=396, Percent_Identity=24.2424242424242, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI45551451, Length=396, Percent_Identity=24.2424242424242, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AAT_SULTO (Q972A2)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_377158.1
- ProteinModelPortal:   Q972A2
- SMR:   Q972A2
- GeneID:   1459224
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST1225
- NMPDR:   fig|273063.1.peg.1326
- HOGENOM:   HBG645860
- OMA:   IIPDPSY
- ProtClustDB:   PRK05764
- BioCyc:   STOK273063:ST1225-MONOMER
- BRENDA:   2.6.1.1
- GO:   GO:0005737
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.1

Molecular weight: Translated: 45406; Mature: 45275

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: BINDING 42-42 BINDING 179-179 BINDING 372-372

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVDDFSLSANSISGESTLVYQDVARQVQKTKGIRIINFGIGQPDLPTFARIREAAKKSL
CCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHH
DEGFTGYTSAYGIDELRQKIAEHLSSKYESVRKEEVIVTPGAKTALYLAFLLYINPGDEV
HCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHEEECCCCEE
IIFDPSFYSYAEVVKMLGGVPVYVKMKFNESTGFSLNLSELESKINKKTKMIVLNNPHNP
EEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEHHHHHHHHCCCEEEEEEECCCCC
TGMVFDPIEIEKLMEITKEKKVLLLSDEIYDYFIYEGKMKSVLEDPDWRDYVIYVNGFSK
CCEEECHHHHHHHHHHHHCCEEEEEEHHHEEEEEECCHHHHHHCCCCCCEEEEEEECCCC
TFSMTGWRLGYVVAKEKVIKKMAEIAANIYTCPTSFAQKGALAAFESFDEVKEMISLFKK
HHCCCCEEHHHHHHHHHHHHHHHHHHHHHEECCHHHHHCCHHHHHHHHHHHHHHHHHHHH
RRDIMYEELKKIKGIQVHKSQGAFYMFPFIGEILKKANLSVKDFSLKLIEEKGVTTIPGE
HHHHHHHHHHHHCCEEEECCCCCEEEHHHHHHHHHHCCCCEEHHEEEEECCCCCEECCCC
VFPLEVGKDFVRLSFAVKEDDIREGIKRMKEFIDMLMTP
EEEHHHCCCEEEEEEEECHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PVDDFSLSANSISGESTLVYQDVARQVQKTKGIRIINFGIGQPDLPTFARIREAAKKSL
CCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHH
DEGFTGYTSAYGIDELRQKIAEHLSSKYESVRKEEVIVTPGAKTALYLAFLLYINPGDEV
HCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHEEECCCCEE
IIFDPSFYSYAEVVKMLGGVPVYVKMKFNESTGFSLNLSELESKINKKTKMIVLNNPHNP
EEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEHHHHHHHHCCCEEEEEEECCCCC
TGMVFDPIEIEKLMEITKEKKVLLLSDEIYDYFIYEGKMKSVLEDPDWRDYVIYVNGFSK
CCEEECHHHHHHHHHHHHCCEEEEEEHHHEEEEEECCHHHHHHCCCCCCEEEEEEECCCC
TFSMTGWRLGYVVAKEKVIKKMAEIAANIYTCPTSFAQKGALAAFESFDEVKEMISLFKK
HHCCCCEEHHHHHHHHHHHHHHHHHHHHHEECCHHHHHCCHHHHHHHHHHHHHHHHHHHH
RRDIMYEELKKIKGIQVHKSQGAFYMFPFIGEILKKANLSVKDFSLKLIEEKGVTTIPGE
HHHHHHHHHHHHCCEEEECCCCCEEEHHHHHHHHHHCCCCEEHHEEEEECCCCCEECCCC
VFPLEVGKDFVRLSFAVKEDDIREGIKRMKEFIDMLMTP
EEEHHHCCCEEEEEEEECHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479