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The map label for this gene is yyaJ [H]

Identifier: 15921427

GI number: 15921427

Start: 1170024

End: 1171370

Strand: Reverse

Name: yyaJ [H]

Synonym: ST1170

Alternate gene names: 15921427

Gene position: 1171370-1170024 (Counterclockwise)

Preceding gene: 15921428

Following gene: 15921422

Centisome position: 43.47

GC content: 35.93

Gene sequence:

>1347_bases
ATGACCATTGCTGGAAGGATTGAAAGATTGCCTTGGACTTCTTTTCATACTAAGTTATTAGCACTCCTAAGCTTAGGAGA
ATTTTTTGAACTTTACGATCTATTTGTTGGAGGATTTGTAGTACAACCAATATCTTCTTTTTATAAAATTCCCTCAGCTG
AAGCAATTTATTATACCATAGCAATCTTCTTTTTAGGTGCATTCGTCGGTGCTATAATATTTACTTATATAGGAGATGTT
ATGGGAAGACGAACAGCACTAATACTTAACATGTTCATAGCCTCGGTAGGACTCTTATTGACTCCATTTTCTCCAAATAT
ATACTTATTAGGTTTGCTAAGGTTTATAACTGGATTAGGTGTTGGGCCAGAAGCATTGATAGTTTTAGATGTTATGATAA
CGGAGTTTTTCCCTTCTAGGATTAGAGGTAGGGCACTGGCTATTGGTTACACCGCTTCTTGGACGGCGCCAATAGTTGTG
GCTATTTTAGCTTATCTATTGATTCCTCATTCTTATATCCTTCAAGGTTGGCAGTGGTTGTATATAATAGGAGGACTGGG
AATACTTACGATTATACCTTTTAGGTTCTTAATTCCAGAATCTCCAAGATGGCTGGAGACTAAAGGGAGAATAGATGAGG
CTGAGAAAATAGTAAATATGATGGAAGAAGTAGCAATAAGAGAAAAGGGGCACTTAAGTGAGCCTCTACAAGTAGAGGTA
GTTACTTCGCAAAAAGTAAAAATATCAGAGTTATTTTCACCACTATATAGGAAGAGGACAATAATGTTATGGATATTTGA
GTTCTTGCAAACTGGAGTATATTACGGATTTGCCTCTTTGGCACCTTCAGTTCTCTATGCTAAAGGTTTTAGCTTAGTTC
ATACCTTAGAGTACTCAATGCTAATTTACACTTCTTACTTTATCAGCTCTCTTGCATCTATTTTCATAATTGATAGTCAG
AAATTTGATAGGAAATGGCAAGTAAGTATTGTAATGTTACTCATGGGTATTGTTGGTTTAGCATTTGGGTTTTCAACTAC
CGCATTAGAAGTTATAACTACAGGATTCTTATTTGGATTTCTGTCTAACATATTTTCAAATGCTTTCCATCAATACGGGG
CGGAATTATACCCAACTAGAATAAGGTCCTTTGCTGACGGTGTTCAGTATTCTCTTAGCAGACTTGGAAACTATGTTTGG
CTTTCTATATTACCTATATTACTCTACTCTAAAGGCCCGGCATTTATGTACGCTGTAGTATTTGTAATGGCATTGATAGT
AACATTAGATGTTGGAATATTAGGACCAAAGGCGTCTCAAATAGAGCTTGAACAACTCTCTAAATAA

Upstream 100 bases:

>100_bases
TATGTTAAAATTTGAATATTCTTATTAATAAAAGAAAGTTCGATTTTAAAACTTATCTGGTCAATAATTTTTAAATAGTC
AAAACAAATTACCTTTCTTC

Downstream 100 bases:

>100_bases
GCCACGTATTTTTTCAAGAAATAGAAGAGCACAATCTCAGCGTTTTAAAAATAAGAATCGGTACTAATTTGAAAGTAAGT
TCTTCGTTACTTTTGATGAA

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MTIAGRIERLPWTSFHTKLLALLSLGEFFELYDLFVGGFVVQPISSFYKIPSAEAIYYTIAIFFLGAFVGAIIFTYIGDV
MGRRTALILNMFIASVGLLLTPFSPNIYLLGLLRFITGLGVGPEALIVLDVMITEFFPSRIRGRALAIGYTASWTAPIVV
AILAYLLIPHSYILQGWQWLYIIGGLGILTIIPFRFLIPESPRWLETKGRIDEAEKIVNMMEEVAIREKGHLSEPLQVEV
VTSQKVKISELFSPLYRKRTIMLWIFEFLQTGVYYGFASLAPSVLYAKGFSLVHTLEYSMLIYTSYFISSLASIFIIDSQ
KFDRKWQVSIVMLLMGIVGLAFGFSTTALEVITTGFLFGFLSNIFSNAFHQYGAELYPTRIRSFADGVQYSLSRLGNYVW
LSILPILLYSKGPAFMYAVVFVMALIVTLDVGILGPKASQIELEQLSK

Sequences:

>Translated_448_residues
MTIAGRIERLPWTSFHTKLLALLSLGEFFELYDLFVGGFVVQPISSFYKIPSAEAIYYTIAIFFLGAFVGAIIFTYIGDV
MGRRTALILNMFIASVGLLLTPFSPNIYLLGLLRFITGLGVGPEALIVLDVMITEFFPSRIRGRALAIGYTASWTAPIVV
AILAYLLIPHSYILQGWQWLYIIGGLGILTIIPFRFLIPESPRWLETKGRIDEAEKIVNMMEEVAIREKGHLSEPLQVEV
VTSQKVKISELFSPLYRKRTIMLWIFEFLQTGVYYGFASLAPSVLYAKGFSLVHTLEYSMLIYTSYFISSLASIFIIDSQ
KFDRKWQVSIVMLLMGIVGLAFGFSTTALEVITTGFLFGFLSNIFSNAFHQYGAELYPTRIRSFADGVQYSLSRLGNYVW
LSILPILLYSKGPAFMYAVVFVMALIVTLDVGILGPKASQIELEQLSK
>Mature_447_residues
TIAGRIERLPWTSFHTKLLALLSLGEFFELYDLFVGGFVVQPISSFYKIPSAEAIYYTIAIFFLGAFVGAIIFTYIGDVM
GRRTALILNMFIASVGLLLTPFSPNIYLLGLLRFITGLGVGPEALIVLDVMITEFFPSRIRGRALAIGYTASWTAPIVVA
ILAYLLIPHSYILQGWQWLYIIGGLGILTIIPFRFLIPESPRWLETKGRIDEAEKIVNMMEEVAIREKGHLSEPLQVEVV
TSQKVKISELFSPLYRKRTIMLWIFEFLQTGVYYGFASLAPSVLYAKGFSLVHTLEYSMLIYTSYFISSLASIFIIDSQK
FDRKWQVSIVMLLMGIVGLAFGFSTTALEVITTGFLFGFLSNIFSNAFHQYGAELYPTRIRSFADGVQYSLSRLGNYVWL
SILPILLYSKGPAFMYAVVFVMALIVTLDVGILGPKASQIELEQLSK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI213021148, Length=475, Percent_Identity=24.4210526315789, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI24308167, Length=432, Percent_Identity=22.6851851851852, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI20070188, Length=390, Percent_Identity=26.1538461538462, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI24497476, Length=390, Percent_Identity=26.1538461538462, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI166064021, Length=374, Percent_Identity=26.2032085561497, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI166197673, Length=362, Percent_Identity=27.3480662983425, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4506999, Length=402, Percent_Identity=28.1094527363184, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI302148518, Length=358, Percent_Identity=27.3743016759777, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI23510410, Length=216, Percent_Identity=31.0185185185185, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4507005, Length=352, Percent_Identity=25, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI24497480, Length=343, Percent_Identity=25.3644314868805, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI24497478, Length=343, Percent_Identity=25.3644314868805, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI157426885, Length=438, Percent_Identity=22.8310502283105, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI216548223, Length=194, Percent_Identity=26.2886597938144, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI24497490, Length=353, Percent_Identity=25.2124645892351, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1788074, Length=420, Percent_Identity=27.8571428571429, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788068, Length=458, Percent_Identity=25.764192139738, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786229, Length=452, Percent_Identity=25.6637168141593, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87082159, Length=414, Percent_Identity=27.0531400966184, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789312, Length=431, Percent_Identity=21.8097447795824, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25145172, Length=380, Percent_Identity=24.7368421052632, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32564663, Length=420, Percent_Identity=23.3333333333333, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193209824, Length=162, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193209133, Length=384, Percent_Identity=24.7395833333333, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320552, Length=302, Percent_Identity=28.476821192053, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322242, Length=284, Percent_Identity=26.7605633802817, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324417, Length=284, Percent_Identity=26.7605633802817, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321886, Length=303, Percent_Identity=28.7128712871287, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320745, Length=306, Percent_Identity=24.5098039215686, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320549, Length=287, Percent_Identity=27.8745644599303, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320550, Length=287, Percent_Identity=27.8745644599303, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI221330907, Length=345, Percent_Identity=26.9565217391304, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648211, Length=346, Percent_Identity=26.3005780346821, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21355657, Length=373, Percent_Identity=25.4691689008043, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922134, Length=238, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24585484, Length=372, Percent_Identity=25, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24649618, Length=355, Percent_Identity=23.6619718309859, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24640198, Length=216, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24640196, Length=216, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24640200, Length=216, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20129657, Length=372, Percent_Identity=25, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI221457681, Length=346, Percent_Identity=23.121387283237, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658792, Length=343, Percent_Identity=21.865889212828, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221457686, Length=338, Percent_Identity=23.3727810650888, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356505, Length=343, Percent_Identity=23.6151603498542, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 50302; Mature: 50171

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAGRIERLPWTSFHTKLLALLSLGEFFELYDLFVGGFVVQPISSFYKIPSAEAIYYTI
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AIFFLGAFVGAIIFTYIGDVMGRRTALILNMFIASVGLLLTPFSPNIYLLGLLRFITGLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
VGPEALIVLDVMITEFFPSRIRGRALAIGYTASWTAPIVVAILAYLLIPHSYILQGWQWL
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHCCHHHH
YIIGGLGILTIIPFRFLIPESPRWLETKGRIDEAEKIVNMMEEVAIREKGHLSEPLQVEV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VTSQKVKISELFSPLYRKRTIMLWIFEFLQTGVYYGFASLAPSVLYAKGFSLVHTLEYSM
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LIYTSYFISSLASIFIIDSQKFDRKWQVSIVMLLMGIVGLAFGFSTTALEVITTGFLFGF
HHHHHHHHHHHHHEEEECCHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LSNIFSNAFHQYGAELYPTRIRSFADGVQYSLSRLGNYVWLSILPILLYSKGPAFMYAVV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHH
FVMALIVTLDVGILGPKASQIELEQLSK
HHHHHHHHHHHHCCCCCCCCCHHHHHCC
>Mature Secondary Structure 
TIAGRIERLPWTSFHTKLLALLSLGEFFELYDLFVGGFVVQPISSFYKIPSAEAIYYTI
CCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AIFFLGAFVGAIIFTYIGDVMGRRTALILNMFIASVGLLLTPFSPNIYLLGLLRFITGLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
VGPEALIVLDVMITEFFPSRIRGRALAIGYTASWTAPIVVAILAYLLIPHSYILQGWQWL
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHCCHHHH
YIIGGLGILTIIPFRFLIPESPRWLETKGRIDEAEKIVNMMEEVAIREKGHLSEPLQVEV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VTSQKVKISELFSPLYRKRTIMLWIFEFLQTGVYYGFASLAPSVLYAKGFSLVHTLEYSM
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LIYTSYFISSLASIFIIDSQKFDRKWQVSIVMLLMGIVGLAFGFSTTALEVITTGFLFGF
HHHHHHHHHHHHHEEEECCHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LSNIFSNAFHQYGAELYPTRIRSFADGVQYSLSRLGNYVWLSILPILLYSKGPAFMYAVV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHH
FVMALIVTLDVGILGPKASQIELEQLSK
HHHHHHHHHHHHCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]