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The map label for this gene is lrp [C]

Identifier: 15921269

GI number: 15921269

Start: 1007929

End: 1008381

Strand: Direct

Name: lrp [C]

Synonym: ST1022

Alternate gene names: 15921269

Gene position: 1007929-1008381 (Clockwise)

Preceding gene: 15921264

Following gene: 15921270

Centisome position: 37.4

GC content: 29.14

Gene sequence:

>453_bases
ATGGATGAAATAGATTTAAGAATTTTGAAAATTCTTCAATATAATGCAAAATATTCTTTAGATGAGATAGCTAGGGAAAT
TAGAATTCCCAAGTCTACCTTATCATATAGAATTAAGAAGTTAGAAAAAGATGGTGTAATTAAGGGTTATTATGCATATA
TTAATCCAGCCTCATTAAACCTTGATTACATAGTAATAACTTCTGTAAAAGCTAAGTATGGTAAAAATTATCATGTGGAG
TTAGGCAATAAGTTAGCACAAATACCAGGGGTTTGGGGAGTATATTTTGTTCTAGGTGATAATGATTTTATTGTAATGGC
TAGATATAAAACCAGAGAGGAGTTCATGGAAAAATTCTTAGAAAGAGTTATGAGTATTCCAGAGGTTGAGAGAACTTCTA
CACAAGTTGTTGTTAAGATAATTAAAGAATCACCAAATATAGTTATCTTTTAA

Upstream 100 bases:

>100_bases
AAGATTATAAGCGATTTTTTGTAAGTCTTTTTTTATTATAAGTGTTGATTAGATATAATTCAAAGTAAAGGCTTATATTT
TTGTTTATAATATACAGTCT

Downstream 100 bases:

>100_bases
CGAAAAATTCATATAATACTTTTCATAATATTTATATATGATTGATAAAAAAGAGCTAAGGGAAATTAGCCTAAAGAAGA
AAAGGGAAAAAAGGTTGACA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MDEIDLRILKILQYNAKYSLDEIAREIRIPKSTLSYRIKKLEKDGVIKGYYAYINPASLNLDYIVITSVKAKYGKNYHVE
LGNKLAQIPGVWGVYFVLGDNDFIVMARYKTREEFMEKFLERVMSIPEVERTSTQVVVKIIKESPNIVIF

Sequences:

>Translated_150_residues
MDEIDLRILKILQYNAKYSLDEIAREIRIPKSTLSYRIKKLEKDGVIKGYYAYINPASLNLDYIVITSVKAKYGKNYHVE
LGNKLAQIPGVWGVYFVLGDNDFIVMARYKTREEFMEKFLERVMSIPEVERTSTQVVVKIIKESPNIVIF
>Mature_150_residues
MDEIDLRILKILQYNAKYSLDEIAREIRIPKSTLSYRIKKLEKDGVIKGYYAYINPASLNLDYIVITSVKAKYGKNYHVE
LGNKLAQIPGVWGVYFVLGDNDFIVMARYKTREEFMEKFLERVMSIPEVERTSTQVVVKIIKESPNIVIF

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=150, Percent_Identity=27.3333333333333, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=21.3333333333333, Blast_Score=60, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR001845
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 17475; Mature: 17475

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEIDLRILKILQYNAKYSLDEIAREIRIPKSTLSYRIKKLEKDGVIKGYYAYINPASLN
CCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCC
LDYIVITSVKAKYGKNYHVELGNKLAQIPGVWGVYFVLGDNDFIVMARYKTREEFMEKFL
CCEEEEEEEEHHHCCEEEEECCCHHHHCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHH
ERVMSIPEVERTSTQVVVKIIKESPNIVIF
HHHHCCCCCCCHHHHHHHHHHHCCCCEEEC
>Mature Secondary Structure
MDEIDLRILKILQYNAKYSLDEIAREIRIPKSTLSYRIKKLEKDGVIKGYYAYINPASLN
CCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCC
LDYIVITSVKAKYGKNYHVELGNKLAQIPGVWGVYFVLGDNDFIVMARYKTREEFMEKFL
CCEEEEEEEEHHHCCEEEEECCCHHHHCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHH
ERVMSIPEVERTSTQVVVKIIKESPNIVIF
HHHHCCCCCCCHHHHHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]