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The map label for this gene is sucC [H]

Identifier: 15921204

GI number: 15921204

Start: 938186

End: 939004

Strand: Reverse

Name: sucC [H]

Synonym: ST0963

Alternate gene names: 15921204

Gene position: 939004-938186 (Counterclockwise)

Preceding gene: 15921205

Following gene: 15921203

Centisome position: 34.85

GC content: 32.48

Gene sequence:

>819_bases
ATGAAGTTAGGAGTTAATAAATTCCTCGTAGAAGAATTTATTCCGCATGAAAAAGAAATCTACTTATCGGCATTAATAGA
TAGAGATGTTGCAGAACCTATTATTGTAGCATCACCAGAAGGTGGAATCGATATAGAGAGTAGCAAAAATGTAAAAATTT
TTCATATACCAATTGAAAGAGGAGTAAGATCTTATGATGTTATTAAAATTGAAAAATATCTTAATGTTAAGGGTCTTGAA
CCCATAATTAAAGGATTATACAAATTGGTTACTGAATATGATGCTGAATTAGCTGAAATAAACCCATTAGCTGTCACAGT
GGATGGAAGACTTTATGCTTTAGATTCAAAAGTAATTTTAGAAGATAACGCATTATTTAGACACCAAGATCTATTAGAAA
AAATTGGAAGATCACCTAGTAAAGATGCCTATGTAGAGTTAGATGGAGATATTGGGATTATAGGTAATGGGGCTGGATTA
ACTATGGCTACCATGGATATGGTTAAATTAATGGGGGGAAGTCCAGCTGATTTCTATGATGTTGGTGGTGGAGCAGACAG
AGAGAAAGTTAAAGAAGCAGTATTGAAGATTGGTTCAAATCCTAAGGTTAAGAAAATTATTATAAATATTTATGGAGGAA
TAACAAAATGTGATGAAGTCGCACTTGGAATAGTTGATGCGTACAGTTTAATAAAGAAACCCATATATGTAAGACTTGTG
GGAACAAACGAAGAACAAGGAAGGAAAATACTTCAAGATAATGGTATTAAATATTATACTGATGCATTAAGTTGCATAGG
TGATGCATTACGCTCATAA

Upstream 100 bases:

>100_bases
AGGAAAAGCTGTAGTTAAATCTCAACTACTTGAAGGAGCAAGAGGAAAAAGAGGATTAGTAAGAGTAACTGAAAATGTTG
AAGAGACTATAAATGAGCTT

Downstream 100 bases:

>100_bases
ATAGGAACACAAGAGTACTAGTTCAGGGAATTACCGGTAAAGAAGGCTCGTTCCACACCAAACAAATGCTCACTTACGGA
ACTAAAATTGTTGCTGGAGT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MKLGVNKFLVEEFIPHEKEIYLSALIDRDVAEPIIVASPEGGIDIESSKNVKIFHIPIERGVRSYDVIKIEKYLNVKGLE
PIIKGLYKLVTEYDAELAEINPLAVTVDGRLYALDSKVILEDNALFRHQDLLEKIGRSPSKDAYVELDGDIGIIGNGAGL
TMATMDMVKLMGGSPADFYDVGGGADREKVKEAVLKIGSNPKVKKIIINIYGGITKCDEVALGIVDAYSLIKKPIYVRLV
GTNEEQGRKILQDNGIKYYTDALSCIGDALRS

Sequences:

>Translated_272_residues
MKLGVNKFLVEEFIPHEKEIYLSALIDRDVAEPIIVASPEGGIDIESSKNVKIFHIPIERGVRSYDVIKIEKYLNVKGLE
PIIKGLYKLVTEYDAELAEINPLAVTVDGRLYALDSKVILEDNALFRHQDLLEKIGRSPSKDAYVELDGDIGIIGNGAGL
TMATMDMVKLMGGSPADFYDVGGGADREKVKEAVLKIGSNPKVKKIIINIYGGITKCDEVALGIVDAYSLIKKPIYVRLV
GTNEEQGRKILQDNGIKYYTDALSCIGDALRS
>Mature_272_residues
MKLGVNKFLVEEFIPHEKEIYLSALIDRDVAEPIIVASPEGGIDIESSKNVKIFHIPIERGVRSYDVIKIEKYLNVKGLE
PIIKGLYKLVTEYDAELAEINPLAVTVDGRLYALDSKVILEDNALFRHQDLLEKIGRSPSKDAYVELDGDIGIIGNGAGL
TMATMDMVKLMGGSPADFYDVGGGADREKVKEAVLKIGSNPKVKKIIINIYGGITKCDEVALGIVDAYSLIKKPIYVRLV
GTNEEQGRKILQDNGIKYYTDALSCIGDALRS

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI157779135, Length=276, Percent_Identity=36.5942028985507, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI11321583, Length=278, Percent_Identity=36.6906474820144, Blast_Score=160, Evalue=8e-40,
Organism=Homo sapiens, GI294862256, Length=262, Percent_Identity=36.6412213740458, Blast_Score=153, Evalue=1e-37,
Organism=Escherichia coli, GI1786948, Length=286, Percent_Identity=41.2587412587413, Blast_Score=165, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17539378, Length=278, Percent_Identity=38.4892086330935, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17567829, Length=263, Percent_Identity=37.6425855513308, Blast_Score=160, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6321683, Length=272, Percent_Identity=38.2352941176471, Blast_Score=162, Evalue=7e-41,
Organism=Drosophila melanogaster, GI21356231, Length=279, Percent_Identity=38.3512544802867, Blast_Score=180, Evalue=9e-46,
Organism=Drosophila melanogaster, GI281361397, Length=274, Percent_Identity=39.4160583941606, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI281361395, Length=274, Percent_Identity=39.4160583941606, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI161078106, Length=273, Percent_Identity=39.1941391941392, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24645208, Length=273, Percent_Identity=39.1941391941392, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29887; Mature: 29887

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGVNKFLVEEFIPHEKEIYLSALIDRDVAEPIIVASPEGGIDIESSKNVKIFHIPIER
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCEEEEEEEHHH
GVRSYDVIKIEKYLNVKGLEPIIKGLYKLVTEYDAELAEINPLAVTVDGRLYALDSKVIL
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCEEEEECCEEEE
EDNALFRHQDLLEKIGRSPSKDAYVELDGDIGIIGNGAGLTMATMDMVKLMGGSPADFYD
ECCCHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEE
VGGGADREKVKEAVLKIGSNPKVKKIIINIYGGITKCDEVALGIVDAYSLIKKPIYVRLV
CCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
GTNEEQGRKILQDNGIKYYTDALSCIGDALRS
ECCHHHHHHHHHHCCCEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLGVNKFLVEEFIPHEKEIYLSALIDRDVAEPIIVASPEGGIDIESSKNVKIFHIPIER
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCEEEEEEEHHH
GVRSYDVIKIEKYLNVKGLEPIIKGLYKLVTEYDAELAEINPLAVTVDGRLYALDSKVIL
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCEEEEECCEEEE
EDNALFRHQDLLEKIGRSPSKDAYVELDGDIGIIGNGAGLTMATMDMVKLMGGSPADFYD
ECCCHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEE
VGGGADREKVKEAVLKIGSNPKVKKIIINIYGGITKCDEVALGIVDAYSLIKKPIYVRLV
CCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
GTNEEQGRKILQDNGIKYYTDALSCIGDALRS
ECCHHHHHHHHHHCCCEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA