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The map label for this gene is nth [C]

Identifier: 15921205

GI number: 15921205

Start: 939196

End: 939918

Strand: Reverse

Name: nth [C]

Synonym: ST0964

Alternate gene names: 15921205

Gene position: 939918-939196 (Counterclockwise)

Preceding gene: 15921206

Following gene: 15921204

Centisome position: 34.88

GC content: 30.57

Gene sequence:

>723_bases
GTGATGAGACGAGCGCACACTGATGAGATGAAGACGTCACTGCGTGCTGATAAGATAATTCAAAAACTTATCCAAGAATT
TGAGAAGAATAAAGAGCTCTTAAGACAAGCTGGGTGGATTGTAAGTGATGTAAATTCGTTTGAATGGTGGGACGGATTAA
AGACAGCTGATGAAATTTTAATTTCATCCATATTAGTACAAATGACTAAGTGGGAAATAGTTAAAAAAGTAATTGAAAGA
CTGAGACAAATAGGTTTAAATAAACTAGATAAATTGGCTAATTTATCAGAAGAAGAAATTGAAGAACTTATTAAAGGAGT
TAATTTTTATAAGACTAAGGCTAAAAGGTTAAAGAAATTAGCAACTATAGTTAAAGAGAAAGGACTAGAAAATATAGTTA
AGAATGAGAAAACTTTGAAAGAAATTGAAGGAATAGGAGACGAGACTGCAGAATCTTTACAACTTTTTGTAGCTAATCTT
CCTGTATTTCCAAGATCCGAATATGCTTCTAGGATTTTAAGCAGAATTTTAGGTGAAAAAATAAGCAAAAAAGAAGCTAA
AATTTTGGCTGAGAGTTATTTAAAAGATGATGTATACAAACTTAAACTTTTTCATGCTGGAATAGTTACCATTGGTAAAA
TTTTTTGTTTAAGTAAACCGAAGTGCAATAGTTGCATATTTAAAGATTTGTGTGCATATTATAAACATGTGGTGAAAAGT
TGA

Upstream 100 bases:

>100_bases
TTGAAGCAGTAGAGAAAGCTCATAAACCTAAGGATTATGAAATAGGTACGCAAAAACTAGTAGATTTAATTTTAAGTGAT
CTAACTAGGAAATAATACTA

Downstream 100 bases:

>100_bases
AACTTTACGAGTTTGAAGGAAAGGAACTTTTTAGGGAAGTAGGAATCCCAGTACCAAAAGGTATAGTTACAGATAAACCA
ATAAAATGGGAAGGAAAAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MMRRAHTDEMKTSLRADKIIQKLIQEFEKNKELLRQAGWIVSDVNSFEWWDGLKTADEILISSILVQMTKWEIVKKVIER
LRQIGLNKLDKLANLSEEEIEELIKGVNFYKTKAKRLKKLATIVKEKGLENIVKNEKTLKEIEGIGDETAESLQLFVANL
PVFPRSEYASRILSRILGEKISKKEAKILAESYLKDDVYKLKLFHAGIVTIGKIFCLSKPKCNSCIFKDLCAYYKHVVKS

Sequences:

>Translated_240_residues
MMRRAHTDEMKTSLRADKIIQKLIQEFEKNKELLRQAGWIVSDVNSFEWWDGLKTADEILISSILVQMTKWEIVKKVIER
LRQIGLNKLDKLANLSEEEIEELIKGVNFYKTKAKRLKKLATIVKEKGLENIVKNEKTLKEIEGIGDETAESLQLFVANL
PVFPRSEYASRILSRILGEKISKKEAKILAESYLKDDVYKLKLFHAGIVTIGKIFCLSKPKCNSCIFKDLCAYYKHVVKS
>Mature_240_residues
MMRRAHTDEMKTSLRADKIIQKLIQEFEKNKELLRQAGWIVSDVNSFEWWDGLKTADEILISSILVQMTKWEIVKKVIER
LRQIGLNKLDKLANLSEEEIEELIKGVNFYKTKAKRLKKLATIVKEKGLENIVKNEKTLKEIEGIGDETAESLQLFVANL
PVFPRSEYASRILSRILGEKISKKEAKILAESYLKDDVYKLKLFHAGIVTIGKIFCLSKPKCNSCIFKDLCAYYKHVVKS

Specific function: Has Both An Apurinic And/Or Apyrimidinic Endonuclease Activity And A DNA N-Glycosylase Activity. Incises Damaged DNA At Cytosines, Thymines And Guanines. Acts On A Damaged Strand, 5' From The Damaged Site. Required For The Repair Of Both Oxidative DNA Da

COG id: COG2231

COG function: function code L; Uncharacterized protein related to Endonuclease III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Nth/MutY family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003651
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: 4.2.99.18

Molecular weight: Translated: 27707; Mature: 27707

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRRAHTDEMKTSLRADKIIQKLIQEFEKNKELLRQAGWIVSDVNSFEWWDGLKTADEIL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHH
ISSILVQMTKWEIVKKVIERLRQIGLNKLDKLANLSEEEIEELIKGVNFYKTKAKRLKKL
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ATIVKEKGLENIVKNEKTLKEIEGIGDETAESLQLFVANLPVFPRSEYASRILSRILGEK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ISKKEAKILAESYLKDDVYKLKLFHAGIVTIGKIFCLSKPKCNSCIFKDLCAYYKHVVKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: 4Fe-4S Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyase [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]