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The map label for this gene is pfpI [H]

Identifier: 15921126

GI number: 15921126

Start: 868317

End: 868838

Strand: Reverse

Name: pfpI [H]

Synonym: ST0890

Alternate gene names: 15921126

Gene position: 868838-868317 (Counterclockwise)

Preceding gene: 15921127

Following gene: 15921125

Centisome position: 32.24

GC content: 38.51

Gene sequence:

>522_bases
ATGAAAGTTCTTTTCATAGTTGGAGATGAATATGAAGATATTGAGCTTCTGTACCCATTCTACAGAGTAATTGAAGAAGG
ATATCAGCCAGTTATTGCAGGTAAAGAGGCTGGGGCAAAGATTGTTGGTAAACACGGTTATTCAGTTGTTGCAGATATAG
CATTTAAAGACGTGAAGGTGGAAGATTATTTAGCTTTAGTTATTCCAGGAGGAAGGGGGCCGGAGAGAATAAGAACTTTG
CCAGAGGTTAAAGAACTAACTAGGAGATTTTTCATAGATAAAAAGCCAGTAGCAGCAATCTGTCACGGTCCTCAAGTGTT
GATTTCTGCTGGCGTAATAAAAGGTAGAAAAGTTACTTCTGTTGCTTCAATTAAAGATGATATAGTAGCTGCAGGAGGAG
AATATGTAGATGCCCCTCTAGTTGAGGATGAAAACTTAATTTCTTCAAGGCATCCAGGGGATCTGCCATACTTTGCTAAA
GGACTGTTAAAGGCTTTAAAAAGTGTGAGAGAAAAAAGCTAA

Upstream 100 bases:

>100_bases
TGTTTCTATGAATGATTAATTTTATCTAATCACGTTGCTTGCAAAGATCATAAATCCAATGAATGATTAATTTTATCTAC
TTAAAAACACAACTACTATT

Downstream 100 bases:

>100_bases
CACGATTTTTTTATTTTTTATTCTTTAATTGCATGTGGATTGTATATTCATATTTCGCAGGGATTTAAGGCTTGAAGATA
ATACGGGGCTTAATTATGCT

Product: protease I

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKVLFIVGDEYEDIELLYPFYRVIEEGYQPVIAGKEAGAKIVGKHGYSVVADIAFKDVKVEDYLALVIPGGRGPERIRTL
PEVKELTRRFFIDKKPVAAICHGPQVLISAGVIKGRKVTSVASIKDDIVAAGGEYVDAPLVEDENLISSRHPGDLPYFAK
GLLKALKSVREKS

Sequences:

>Translated_173_residues
MKVLFIVGDEYEDIELLYPFYRVIEEGYQPVIAGKEAGAKIVGKHGYSVVADIAFKDVKVEDYLALVIPGGRGPERIRTL
PEVKELTRRFFIDKKPVAAICHGPQVLISAGVIKGRKVTSVASIKDDIVAAGGEYVDAPLVEDENLISSRHPGDLPYFAK
GLLKALKSVREKS
>Mature_173_residues
MKVLFIVGDEYEDIELLYPFYRVIEEGYQPVIAGKEAGAKIVGKHGYSVVADIAFKDVKVEDYLALVIPGGRGPERIRTL
PEVKELTRRFFIDKKPVAAICHGPQVLISAGVIKGRKVTSVASIKDDIVAAGGEYVDAPLVEDENLISSRHPGDLPYFAK
GLLKALKSVREKS

Specific function: Highly stable protease. Although the physiological function is unclear it is the dominant protease in P.furiosus [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=167, Percent_Identity=40.1197604790419, Blast_Score=117, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17558714, Length=159, Percent_Identity=30.188679245283, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 18967; Mature: 18967

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLFIVGDEYEDIELLYPFYRVIEEGYQPVIAGKEAGAKIVGKHGYSVVADIAFKDVKV
CEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCCEEEEEHHHHCCEE
EDYLALVIPGGRGPERIRTLPEVKELTRRFFIDKKPVAAICHGPQVLISAGVIKGRKVTS
CCEEEEEEECCCCHHHHHCCHHHHHHHHHHCCCCCCCEEECCCCHHHHHHCCCCCCCHHH
VASIKDDIVAAGGEYVDAPLVEDENLISSRHPGDLPYFAKGLLKALKSVREKS
HHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVLFIVGDEYEDIELLYPFYRVIEEGYQPVIAGKEAGAKIVGKHGYSVVADIAFKDVKV
CEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCCEEEEEHHHHCCEE
EDYLALVIPGGRGPERIRTLPEVKELTRRFFIDKKPVAAICHGPQVLISAGVIKGRKVTS
CCEEEEEEECCCCHHHHHCCHHHHHHHHHHCCCCCCCEEECCCCHHHHHHCCCCCCCHHH
VASIKDDIVAAGGEYVDAPLVEDENLISSRHPGDLPYFAKGLLKALKSVREKS
HHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8626329 [H]