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The map label for this gene is pknJ [H]

Identifier: 15920911

GI number: 15920911

Start: 668187

End: 670121

Strand: Direct

Name: pknJ [H]

Synonym: ST0686

Alternate gene names: 15920911

Gene position: 668187-670121 (Clockwise)

Preceding gene: 15920910

Following gene: 15920912

Centisome position: 24.8

GC content: 33.44

Gene sequence:

>1935_bases
ATGATAAGAAAAGTTTTATCCATGAATAGGGAATTACTTGCTACATCTATTTTAGCTACAGCTGGTACTTTTGTTATATA
CATAATTTCTCCCGGTTTTCTCCTTTCATCCCCCTTACTCCTTCTAGGTCTTATATTTTCCTATATTGGTTCCTTTTATA
GATACGTAACTCCAGTTACATTCTTACTTTCTCTAATCCCTTTATTCTTCATTAAATCTACTTATGCACTCATTGGTATT
GCTATAGGAATTCTAGGTATACTAATTCCTTGGGTATGGGAGTTAATCATACTAATTGGTTATATAATATTTCTTTTACT
CCCTAATTTAGTGACAAATATTGGTATACAACCTATAATATTCTCTTACGCAATTTACTCAACTCTTGCTTTTGCAAATA
TTAGGGCGATCACTGGAAAAGGATATCCTGCAGTTGTAAAAATTGAAGGTTTAACTACTTGCTATGCAGAAGTTAACGGT
GTATTTACAACTATTAATCGTATTGTAAGGGGTAAGAAAAGAGTGGAGATAAGACTATGTCCTCAGTACTTTAACGGCAC
ATATTATGTACCAGATACTGCAACAATAACAGCTAAAGAAGGACAAGTTAAAGTGGTAAAGTTCTCAGCTACTAACAACT
TACCAATAGATAAATTTCCTCATTGTTTCTCTTACTTTTATGCTAAAGGTTTACCAATGAATGCTTCATGGTCTATAATT
ATTAACAATGTAGAGTATACTTCTAAAGATTCTAACTCACCAATAATAGTTCCAATGCCAAATGTCTTAGAAGTTATGTG
GAATGCAAAAGATATAATAATAGGTAATGTCATCTTTAGGCCTTTAACTTATTCGGGAATCGCAAAAAGAGGAGAGAAGA
TTATTATCGAGTATAATAGTTATGTTGCACAACAACAAGTTGCTTTAGCATCTCAACAACAAAAGAATTTACCACCTCTA
GATAAGTGGGATCCTAATTTGTGGATCGGAAAAGAACTTTATGGATACAGAGTAGTTTCAGTCATCGGTTCTGGTGGTAG
TGGTTATGTTCTAAAAGCTGAGAAAGATAATGTGTTTTACGCAGTAAAAGTTTTCTCCCTATCCCAATTATCGCGCGCAC
AACTCACTATATCCGCTTCTTCAAGCTTTGATGAGATGTTTAAAGAGTCTGAGACGTTAAAGCAACTATCAAGAAACCCA
AAGTTTGTAACAATTTTAGGCTTTTACATAGATTCAAATAATATTAAATCAGCATTGAAGGGAGATGTTAATACATATTA
CAACTATCCACCCGCAATAGTAATGGAGTTTATGGAAGGAGGTACAGCAAAGGACTTATTAACAACATCAATTATATATT
CCACTTATTGGCCTCTTATTGTTAAAGAGATTATCAAAGAAATTGCATACGCCCTGGACTTTCTCCATTCAAAAGGGTTC
GTGCATCTTGATGTAAAACCAGAAAATATCTTCTTTTCTAGAAATTTAGGAAATAATCCGGAAGAAATATACAAAAATAT
TTCTAGTTCAATAAAATTAGGTGATTTAGGTTCTGCTGTAAGAATAGGTGAAAGATTTTATCAAGCTACTCCTTCTTATT
CTCCCCCAGAGCAGATAGAAGCTATAATTACTGGTAAGGGTGCAGATCCGAAAATGGATATCTTTGCACTAGGAATGACA
GCTTATGTCCTACTCACTGGAAAAAATGATAATCCGATTTCTGACAATCTAAATAAAGCTATTGATGCATATATGGCTGG
GAATGTTGGAGAGGCATTAAAACTTATACAGAATGCAAAACAAATACTATCTTCTTGGAGACCTATATTACCGCAAAATA
CACCAAGCGAACTTACTAGAGTGATAGTATATAGTATAAACATTAATCCATTAAGTAGACCTTCGGCAAAACAAATAGTC
GACTTACTTAAGTAA

Upstream 100 bases:

>100_bases
TTTTAAAACAGATATTGTTATCTTTTTAAAAAACTTAAAATTTCAAGAAAATAAATACAATTTCATGAGCAAAAGGGACT
CGTTACATTAAACTTATATA

Downstream 100 bases:

>100_bases
GAAATTCTTCATTTCCCTCTAGTTACTATAAACTATTCGAAAGCTTTATAGATTAGTAATTAAAGAAAAGTCTTATGAAA
TATGATGTAACTGTTATTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MIRKVLSMNRELLATSILATAGTFVIYIISPGFLLSSPLLLLGLIFSYIGSFYRYVTPVTFLLSLIPLFFIKSTYALIGI
AIGILGILIPWVWELIILIGYIIFLLLPNLVTNIGIQPIIFSYAIYSTLAFANIRAITGKGYPAVVKIEGLTTCYAEVNG
VFTTINRIVRGKKRVEIRLCPQYFNGTYYVPDTATITAKEGQVKVVKFSATNNLPIDKFPHCFSYFYAKGLPMNASWSII
INNVEYTSKDSNSPIIVPMPNVLEVMWNAKDIIIGNVIFRPLTYSGIAKRGEKIIIEYNSYVAQQQVALASQQQKNLPPL
DKWDPNLWIGKELYGYRVVSVIGSGGSGYVLKAEKDNVFYAVKVFSLSQLSRAQLTISASSSFDEMFKESETLKQLSRNP
KFVTILGFYIDSNNIKSALKGDVNTYYNYPPAIVMEFMEGGTAKDLLTTSIIYSTYWPLIVKEIIKEIAYALDFLHSKGF
VHLDVKPENIFFSRNLGNNPEEIYKNISSSIKLGDLGSAVRIGERFYQATPSYSPPEQIEAIITGKGADPKMDIFALGMT
AYVLLTGKNDNPISDNLNKAIDAYMAGNVGEALKLIQNAKQILSSWRPILPQNTPSELTRVIVYSININPLSRPSAKQIV
DLLK

Sequences:

>Translated_644_residues
MIRKVLSMNRELLATSILATAGTFVIYIISPGFLLSSPLLLLGLIFSYIGSFYRYVTPVTFLLSLIPLFFIKSTYALIGI
AIGILGILIPWVWELIILIGYIIFLLLPNLVTNIGIQPIIFSYAIYSTLAFANIRAITGKGYPAVVKIEGLTTCYAEVNG
VFTTINRIVRGKKRVEIRLCPQYFNGTYYVPDTATITAKEGQVKVVKFSATNNLPIDKFPHCFSYFYAKGLPMNASWSII
INNVEYTSKDSNSPIIVPMPNVLEVMWNAKDIIIGNVIFRPLTYSGIAKRGEKIIIEYNSYVAQQQVALASQQQKNLPPL
DKWDPNLWIGKELYGYRVVSVIGSGGSGYVLKAEKDNVFYAVKVFSLSQLSRAQLTISASSSFDEMFKESETLKQLSRNP
KFVTILGFYIDSNNIKSALKGDVNTYYNYPPAIVMEFMEGGTAKDLLTTSIIYSTYWPLIVKEIIKEIAYALDFLHSKGF
VHLDVKPENIFFSRNLGNNPEEIYKNISSSIKLGDLGSAVRIGERFYQATPSYSPPEQIEAIITGKGADPKMDIFALGMT
AYVLLTGKNDNPISDNLNKAIDAYMAGNVGEALKLIQNAKQILSSWRPILPQNTPSELTRVIVYSININPLSRPSAKQIV
DLLK
>Mature_644_residues
MIRKVLSMNRELLATSILATAGTFVIYIISPGFLLSSPLLLLGLIFSYIGSFYRYVTPVTFLLSLIPLFFIKSTYALIGI
AIGILGILIPWVWELIILIGYIIFLLLPNLVTNIGIQPIIFSYAIYSTLAFANIRAITGKGYPAVVKIEGLTTCYAEVNG
VFTTINRIVRGKKRVEIRLCPQYFNGTYYVPDTATITAKEGQVKVVKFSATNNLPIDKFPHCFSYFYAKGLPMNASWSII
INNVEYTSKDSNSPIIVPMPNVLEVMWNAKDIIIGNVIFRPLTYSGIAKRGEKIIIEYNSYVAQQQVALASQQQKNLPPL
DKWDPNLWIGKELYGYRVVSVIGSGGSGYVLKAEKDNVFYAVKVFSLSQLSRAQLTISASSSFDEMFKESETLKQLSRNP
KFVTILGFYIDSNNIKSALKGDVNTYYNYPPAIVMEFMEGGTAKDLLTTSIIYSTYWPLIVKEIIKEIAYALDFLHSKGF
VHLDVKPENIFFSRNLGNNPEEIYKNISSSIKLGDLGSAVRIGERFYQATPSYSPPEQIEAIITGKGADPKMDIFALGMT
AYVLLTGKNDNPISDNLNKAIDAYMAGNVGEALKLIQNAKQILSSWRPILPQNTPSELTRVIVYSININPLSRPSAKQIV
DLLK

Specific function: Unknown

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI4507831, Length=245, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI189491753, Length=254, Percent_Identity=23.2283464566929, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI189491751, Length=254, Percent_Identity=23.2283464566929, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4505601, Length=254, Percent_Identity=23.2283464566929, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI189491759, Length=254, Percent_Identity=23.2283464566929, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI32483399, Length=254, Percent_Identity=24.0157480314961, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI189491757, Length=254, Percent_Identity=23.2283464566929, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI189491755, Length=254, Percent_Identity=23.2283464566929, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI156713428, Length=163, Percent_Identity=31.9018404907975, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI156713430, Length=163, Percent_Identity=31.9018404907975, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI30089960, Length=241, Percent_Identity=26.5560165975104, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI42794769, Length=254, Percent_Identity=23.2283464566929, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI190886457, Length=254, Percent_Identity=23.2283464566929, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI30089962, Length=241, Percent_Identity=26.5560165975104, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI20149547, Length=312, Percent_Identity=25, Blast_Score=67, Evalue=7e-11,
Organism=Homo sapiens, GI55743134, Length=312, Percent_Identity=25, Blast_Score=67, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71982783, Length=257, Percent_Identity=26.0700389105058, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71982774, Length=257, Percent_Identity=26.0700389105058, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71982766, Length=257, Percent_Identity=26.0700389105058, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25145908, Length=242, Percent_Identity=27.6859504132231, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321780, Length=312, Percent_Identity=25.9615384615385, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6325053, Length=239, Percent_Identity=23.8493723849372, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324031, Length=261, Percent_Identity=22.6053639846743, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320102, Length=315, Percent_Identity=24.7619047619048, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647440, Length=237, Percent_Identity=24.8945147679325, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24647442, Length=237, Percent_Identity=24.8945147679325, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17864254, Length=256, Percent_Identity=24.609375, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644584, Length=256, Percent_Identity=24.609375, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644586, Length=256, Percent_Identity=24.609375, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221378052, Length=256, Percent_Identity=24.21875, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007536, Length=236, Percent_Identity=26.6949152542373, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007530, Length=236, Percent_Identity=26.6949152542373, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24649791, Length=265, Percent_Identity=25.6603773584906, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24643817, Length=284, Percent_Identity=25, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI116007532, Length=236, Percent_Identity=26.6949152542373, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI116007534, Length=236, Percent_Identity=26.6949152542373, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR008271 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 71748; Mature: 71748

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS00108 PROTEIN_KINASE_ST ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRKVLSMNRELLATSILATAGTFVIYIISPGFLLSSPLLLLGLIFSYIGSFYRYVTPVT
CCHHHHHCCHHHHHHHHHHHCCCEEEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHH
FLLSLIPLFFIKSTYALIGIAIGILGILIPWVWELIILIGYIIFLLLPNLVTNIGIQPII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FSYAIYSTLAFANIRAITGKGYPAVVKIEGLTTCYAEVNGVFTTINRIVRGKKRVEIRLC
HHHHHHHHHHHHHEEEEECCCCCEEEEECCCEEEHHHHHHHHHHHHHHHCCCCEEEEEEC
PQYFNGTYYVPDTATITAKEGQVKVVKFSATNNLPIDKFPHCFSYFYAKGLPMNASWSII
HHHHCCEEECCCCEEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEE
INNVEYTSKDSNSPIIVPMPNVLEVMWNAKDIIIGNVIFRPLTYSGIAKRGEKIIIEYNS
EECEEECCCCCCCCEEEECCHHHHHHHCCCCEEEEHHHHCCCCHHHHHCCCCEEEEEECH
YVAQQQVALASQQQKNLPPLDKWDPNLWIGKELYGYRVVSVIGSGGSGYVLKAEKDNVFY
HHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHCEEEEEEEECCCCCEEEEECCCCEEE
AVKVFSLSQLSRAQLTISASSSFDEMFKESETLKQLSRNPKFVTILGFYIDSNNIKSALK
EEEEEEHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHC
GDVNTYYNYPPAIVMEFMEGGTAKDLLTTSIIYSTYWPLIVKEIIKEIAYALDFLHSKGF
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VHLDVKPENIFFSRNLGNNPEEIYKNISSSIKLGDLGSAVRIGERFYQATPSYSPPEQIE
EEEEECCCCEEEECCCCCCHHHHHHHHHCCEEECCCCHHHHHHHHHHHCCCCCCCHHHHE
AIITGKGADPKMDIFALGMTAYVLLTGKNDNPISDNLNKAIDAYMAGNVGEALKLIQNAK
EEEECCCCCCCCEEEEECEEEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
QILSSWRPILPQNTPSELTRVIVYSININPLSRPSAKQIVDLLK
HHHHCCCCCCCCCCHHHHEEEEEEEEECCCCCCCCHHHHHHHHC
>Mature Secondary Structure
MIRKVLSMNRELLATSILATAGTFVIYIISPGFLLSSPLLLLGLIFSYIGSFYRYVTPVT
CCHHHHHCCHHHHHHHHHHHCCCEEEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHH
FLLSLIPLFFIKSTYALIGIAIGILGILIPWVWELIILIGYIIFLLLPNLVTNIGIQPII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FSYAIYSTLAFANIRAITGKGYPAVVKIEGLTTCYAEVNGVFTTINRIVRGKKRVEIRLC
HHHHHHHHHHHHHEEEEECCCCCEEEEECCCEEEHHHHHHHHHHHHHHHCCCCEEEEEEC
PQYFNGTYYVPDTATITAKEGQVKVVKFSATNNLPIDKFPHCFSYFYAKGLPMNASWSII
HHHHCCEEECCCCEEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEE
INNVEYTSKDSNSPIIVPMPNVLEVMWNAKDIIIGNVIFRPLTYSGIAKRGEKIIIEYNS
EECEEECCCCCCCCEEEECCHHHHHHHCCCCEEEEHHHHCCCCHHHHHCCCCEEEEEECH
YVAQQQVALASQQQKNLPPLDKWDPNLWIGKELYGYRVVSVIGSGGSGYVLKAEKDNVFY
HHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHCEEEEEEEECCCCCEEEEECCCCEEE
AVKVFSLSQLSRAQLTISASSSFDEMFKESETLKQLSRNPKFVTILGFYIDSNNIKSALK
EEEEEEHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHC
GDVNTYYNYPPAIVMEFMEGGTAKDLLTTSIIYSTYWPLIVKEIIKEIAYALDFLHSKGF
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VHLDVKPENIFFSRNLGNNPEEIYKNISSSIKLGDLGSAVRIGERFYQATPSYSPPEQIE
EEEEECCCCEEEECCCCCCHHHHHHHHHCCEEECCCCHHHHHHHHHHHCCCCCCCHHHHE
AIITGKGADPKMDIFALGMTAYVLLTGKNDNPISDNLNKAIDAYMAGNVGEALKLIQNAK
EEEECCCCCCCCEEEEECEEEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
QILSSWRPILPQNTPSELTRVIVYSININPLSRPSAKQIVDLLK
HHHHCCCCCCCCCCHHHHEEEEEEEEECCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]