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The map label for this gene is frdB [H]

Identifier: 15920714

GI number: 15920714

Start: 497128

End: 498090

Strand: Direct

Name: frdB [H]

Synonym: ST0498

Alternate gene names: 15920714

Gene position: 497128-498090 (Clockwise)

Preceding gene: 15920713

Following gene: 15920715

Centisome position: 18.45

GC content: 33.96

Gene sequence:

>963_bases
ATGTCTCTACAAAATGAAGAGATGGATGTAGTACTTAAGATAAAGAGATATTCTCCTGAAAAAGGATATTGGTGGCAAGA
ATATAAATTAAAAGTTGATAGATTTACTCAATTTACCGAGGCTTTAAGAAGAATTAAAAGTGAACAAGATCCTACGCTTG
CATACAGAGCATCTTGTCATATGGCAGTTTGCGGAAGTTGTGGAATGAAAATTAATGGAGAACCAAGACTTGCATGTAAA
ACATTAGTCATTGATATGGCAAAGAAATACGGTTCTAATGTTATCACAATAGAGCCGATGGATTATTTTAAACCAGTTAA
AGATCTTATTGTTGATTTAGATGAATTTTATCAAAGAATGTATAAAGTTAAACCTAGACTTTATCCTCATAAGGAAGTTT
TAGAAGGTAATGTTGAACAAAGATTAAAACCTGAAGATCAGAGAGAACTTTGGAAATTCGCTCAATGTATATGGTGCGGG
CTATGTGTATCAGCTTGTCCGAGTGTTAAAATGGATCCAGAATTTTTAGGTCCTGCTGCTCATGCTAAAGGTTATAGATT
CCTAGCCGATCCCAGAGACACGATTACTGAAGAGAGGATGAAGATTCTTATAGATAGTGCATGGCGTTGTACATACTGTT
ATATGTGCTATAATGTTTGTCCAAGAGATATAGAACCTGTAACAGCTATTAAGAAAACTAGGGCTTATACTAGATTAGCT
AAAGAAAAGACGTCAGTAGCACAAACTGGAGAGAAGCATATTGAAGCAATATTTAATTCTCTAGTAGAATCTGGAAAACT
AGAAGAGGCTAAGGTTTATCTCAGTACGTATGGATTGCTTGGTTCCATAAAAGATTTCATTTATCTTTTCCAATCTGGTA
AAGTTAAGTATGCTTTAGTAAAAGAGAAACCAGTTGAAAATATAAGTGAGGTCAGGAAAATTCTTAGTGGTGATAATAAA
TGA

Upstream 100 bases:

>100_bases
CTCAAACATACGATAGCATATCTGAGAGGTAATAGTGTAGAGATTACATATAAACCTGTAAAAATGACAAAATGGAAACC
AGAAGCTAGGGTGTATTAAA

Downstream 100 bases:

>100_bases
GCTATGCGTATTATCCAGGTTGTGCAACTCATGGGCTTTCTAAAGATGTAGATATCGCAACAAGAAAAGTATTCGAAACC
TTAGGGTTAAAGCTAGAAGA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSLQNEEMDVVLKIKRYSPEKGYWWQEYKLKVDRFTQFTEALRRIKSEQDPTLAYRASCHMAVCGSCGMKINGEPRLACK
TLVIDMAKKYGSNVITIEPMDYFKPVKDLIVDLDEFYQRMYKVKPRLYPHKEVLEGNVEQRLKPEDQRELWKFAQCIWCG
LCVSACPSVKMDPEFLGPAAHAKGYRFLADPRDTITEERMKILIDSAWRCTYCYMCYNVCPRDIEPVTAIKKTRAYTRLA
KEKTSVAQTGEKHIEAIFNSLVESGKLEEAKVYLSTYGLLGSIKDFIYLFQSGKVKYALVKEKPVENISEVRKILSGDNK

Sequences:

>Translated_320_residues
MSLQNEEMDVVLKIKRYSPEKGYWWQEYKLKVDRFTQFTEALRRIKSEQDPTLAYRASCHMAVCGSCGMKINGEPRLACK
TLVIDMAKKYGSNVITIEPMDYFKPVKDLIVDLDEFYQRMYKVKPRLYPHKEVLEGNVEQRLKPEDQRELWKFAQCIWCG
LCVSACPSVKMDPEFLGPAAHAKGYRFLADPRDTITEERMKILIDSAWRCTYCYMCYNVCPRDIEPVTAIKKTRAYTRLA
KEKTSVAQTGEKHIEAIFNSLVESGKLEEAKVYLSTYGLLGSIKDFIYLFQSGKVKYALVKEKPVENISEVRKILSGDNK
>Mature_319_residues
SLQNEEMDVVLKIKRYSPEKGYWWQEYKLKVDRFTQFTEALRRIKSEQDPTLAYRASCHMAVCGSCGMKINGEPRLACKT
LVIDMAKKYGSNVITIEPMDYFKPVKDLIVDLDEFYQRMYKVKPRLYPHKEVLEGNVEQRLKPEDQRELWKFAQCIWCGL
CVSACPSVKMDPEFLGPAAHAKGYRFLADPRDTITEERMKILIDSAWRCTYCYMCYNVCPRDIEPVTAIKKTRAYTRLAK
EKTSVAQTGEKHIEAIFNSLVESGKLEEAKVYLSTYGLLGSIKDFIYLFQSGKVKYALVKEKPVENISEVRKILSGDNK

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=237, Percent_Identity=34.5991561181435, Blast_Score=125, Evalue=5e-29,
Organism=Escherichia coli, GI1790596, Length=233, Percent_Identity=33.9055793991416, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786943, Length=235, Percent_Identity=35.3191489361702, Blast_Score=134, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17533915, Length=232, Percent_Identity=30.6034482758621, Blast_Score=115, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6322987, Length=236, Percent_Identity=33.8983050847458, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24643156, Length=225, Percent_Identity=33.3333333333333, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI17137106, Length=200, Percent_Identity=35, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 37050; Mature: 36919

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQNEEMDVVLKIKRYSPEKGYWWQEYKLKVDRFTQFTEALRRIKSEQDPTLAYRASCH
CCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHCCC
MAVCGSCGMKINGEPRLACKTLVIDMAKKYGSNVITIEPMDYFKPVKDLIVDLDEFYQRM
HHHHCCCCCEECCCCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
YKVKPRLYPHKEVLEGNVEQRLKPEDQRELWKFAQCIWCGLCVSACPSVKMDPEFLGPAA
HHHCCCCCCCHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHH
HAKGYRFLADPRDTITEERMKILIDSAWRCTYCYMCYNVCPRDIEPVTAIKKTRAYTRLA
HCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
KEKTSVAQTGEKHIEAIFNSLVESGKLEEAKVYLSTYGLLGSIKDFIYLFQSGKVKYALV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
KEKPVENISEVRKILSGDNK
CCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLQNEEMDVVLKIKRYSPEKGYWWQEYKLKVDRFTQFTEALRRIKSEQDPTLAYRASCH
CCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHCCC
MAVCGSCGMKINGEPRLACKTLVIDMAKKYGSNVITIEPMDYFKPVKDLIVDLDEFYQRM
HHHHCCCCCEECCCCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
YKVKPRLYPHKEVLEGNVEQRLKPEDQRELWKFAQCIWCGLCVSACPSVKMDPEFLGPAA
HHHCCCCCCCHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHH
HAKGYRFLADPRDTITEERMKILIDSAWRCTYCYMCYNVCPRDIEPVTAIKKTRAYTRLA
HCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
KEKTSVAQTGEKHIEAIFNSLVESGKLEEAKVYLSTYGLLGSIKDFIYLFQSGKVKYALV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
KEKPVENISEVRKILSGDNK
CCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]