Click here to switch to the map view.

The map label for this gene is idsA [H]

Identifier: 15920702

GI number: 15920702

Start: 486170

End: 487021

Strand: Direct

Name: idsA [H]

Synonym: ST0487

Alternate gene names: 15920702

Gene position: 486170-487021 (Clockwise)

Preceding gene: 15920701

Following gene: 15920703

Centisome position: 18.04

GC content: 31.46

Gene sequence:

>852_bases
GTGGATTTACTTTCTTATTGGAAAAAGAGCAAGGAGATCATTGATAAATTAGTTGACGATTATTTAGTTGATATTAAAGA
TTGGCAATTATTAGAAGTTAGTAAATATATACTAAAGGATGGGAAGAGATTTAGGGGGACATTAACATTTTTATTTACAG
AAGCTCTTAATGGGGATATAAAAAATGCATATAAAGCAGCTCTTGCTTCAGAGATTCTTCATTCCGCATCTCTTGCATTG
GATGATATTGTAGATTATGATATAATTAGAAGAGGAGGGAGTTCAGCTTGGGCAATTTATACTAACAGGAAAGTTATCTT
TATTACCAATTATCTAATTCCCTCAGCATTAAATATAATCTCTACTTACGGAGAAGAGGCGTTAAAAATTAGTATACAAC
TGTGGAAGGATACGGCTGTAGGTGCTTTAAAGGATATATTTGGTTCTCCTTCAGAATATCTTTCTACGATCGAACTAAAA
ACCTCTAGTTTATTTAAACTATCTACGATGTTAGCCTCATTTGCATCTCATAGAGAAGATTTAGTGGAAGAAACTTTAGA
TATAGGGAAATATATAGGAATCGCCTATCAATTAGTTGATGATTATATAGATTGTGTAAAATATGAAAGAGGAGAATTAA
AGGAGCTAACTGGAAGTGCTAAACAGTTATATGAACTTAAAGGGAAAGAGTATAAAGAGTTTGTAAAGAAGCAATATGAA
AATGCTTTAACTAATTACTTAGATATTGTAAGAAAATTGGAAATAAGTCAAGATTTTACTGAAGCTATAATATCGTTGCC
AACTTTTTTAACGAAGGGGCTTTTAAACGAAGCCGGGCTGGATAAATTATAA

Upstream 100 bases:

>100_bases
AATGTGAGAGAAATTCTATTAGATATAGATCCTCTTCTAGCACCAATTTATTTAATTCTTATGACATATTTATTTAAGCG
AGTTAAAGGAGGATTATAAA

Downstream 100 bases:

>100_bases
AAAGTCTTCTATCGAGTGTTCACTTGGTGGATTGATATTAGAATAGCAGTTATTCATGAATCTCAAAAAATTACAGAGTC
AGCTAAGCAACTTCTACTAG

Product: isoprenyl diphosphate synthase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MDLLSYWKKSKEIIDKLVDDYLVDIKDWQLLEVSKYILKDGKRFRGTLTFLFTEALNGDIKNAYKAALASEILHSASLAL
DDIVDYDIIRRGGSSAWAIYTNRKVIFITNYLIPSALNIISTYGEEALKISIQLWKDTAVGALKDIFGSPSEYLSTIELK
TSSLFKLSTMLASFASHREDLVEETLDIGKYIGIAYQLVDDYIDCVKYERGELKELTGSAKQLYELKGKEYKEFVKKQYE
NALTNYLDIVRKLEISQDFTEAIISLPTFLTKGLLNEAGLDKL

Sequences:

>Translated_283_residues
MDLLSYWKKSKEIIDKLVDDYLVDIKDWQLLEVSKYILKDGKRFRGTLTFLFTEALNGDIKNAYKAALASEILHSASLAL
DDIVDYDIIRRGGSSAWAIYTNRKVIFITNYLIPSALNIISTYGEEALKISIQLWKDTAVGALKDIFGSPSEYLSTIELK
TSSLFKLSTMLASFASHREDLVEETLDIGKYIGIAYQLVDDYIDCVKYERGELKELTGSAKQLYELKGKEYKEFVKKQYE
NALTNYLDIVRKLEISQDFTEAIISLPTFLTKGLLNEAGLDKL
>Mature_283_residues
MDLLSYWKKSKEIIDKLVDDYLVDIKDWQLLEVSKYILKDGKRFRGTLTFLFTEALNGDIKNAYKAALASEILHSASLAL
DDIVDYDIIRRGGSSAWAIYTNRKVIFITNYLIPSALNIISTYGEEALKISIQLWKDTAVGALKDIFGSPSEYLSTIELK
TSSLFKLSTMLASFASHREDLVEETLDIGKYIGIAYQLVDDYIDCVKYERGELKELTGSAKQLYELKGKEYKEFVKKQYE
NALTNYLDIVRKLEISQDFTEAIISLPTFLTKGLLNEAGLDKL

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789578, Length=191, Percent_Identity=26.7015706806283, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17505681, Length=207, Percent_Identity=24.6376811594203, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24651612, Length=190, Percent_Identity=30, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 32186; Mature: 32186

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLSYWKKSKEIIDKLVDDYLVDIKDWQLLEVSKYILKDGKRFRGTLTFLFTEALNGDI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHH
KNAYKAALASEILHSASLALDDIVDYDIIRRGGSSAWAIYTNRKVIFITNYLIPSALNII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEECHHHHHHHHHH
STYGEEALKISIQLWKDTAVGALKDIFGSPSEYLSTIELKTSSLFKLSTMLASFASHRED
HHHCHHHHEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVEETLDIGKYIGIAYQLVDDYIDCVKYERGELKELTGSAKQLYELKGKEYKEFVKKQYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
NALTNYLDIVRKLEISQDFTEAIISLPTFLTKGLLNEAGLDKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDLLSYWKKSKEIIDKLVDDYLVDIKDWQLLEVSKYILKDGKRFRGTLTFLFTEALNGDI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHH
KNAYKAALASEILHSASLALDDIVDYDIIRRGGSSAWAIYTNRKVIFITNYLIPSALNII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEECHHHHHHHHHH
STYGEEALKISIQLWKDTAVGALKDIFGSPSEYLSTIELKTSSLFKLSTMLASFASHRED
HHHCHHHHEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVEETLDIGKYIGIAYQLVDDYIDCVKYERGELKELTGSAKQLYELKGKEYKEFVKKQYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
NALTNYLDIVRKLEISQDFTEAIISLPTFLTKGLLNEAGLDKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7979381 [H]