Click here to switch to the map view.

The map label for this gene is ribH

Identifier: 15920597

GI number: 15920597

Start: 406436

End: 406909

Strand: Direct

Name: ribH

Synonym: ST0394

Alternate gene names: 15920597

Gene position: 406436-406909 (Clockwise)

Preceding gene: 15920596

Following gene: 15920598

Centisome position: 15.08

GC content: 35.44

Gene sequence:

>474_bases
ATGAAAATGCCGGACCAATCGATTAACTTAGCTATAGTAGTTGCTGAATTTAATTACGATATAACGTATCTGATGTTACA
AAGAGCAATAGCTCATGCTAAGTTCCTTGGTGCAAATGTAAAGGTTGTATTTAAAGTTCCAGGTAGCTATGATATGGCAA
TAGCTGTGAAAGAGCTACTAAAAAGAGATGATATAGATGCTGTTGTTACTTTAGGTGCAGTAATAAAAGGCGAAACAAAA
CATGATGAAATAGTAGCTACTCAAACTGCAAGAAAAATATTAGATTTATCAGTAGAATATGGAAAGCCTGTAACCTTGGG
TATTATAGGTCACGGAGTTACGCATGAGCAAGCGGTGGAAAGAATAGAGGAGTATTCCACAAGAGCTGTTGAGGCTGCAA
TAAAATTGGCTAAGAGGTTAAGAGAACTAAGAAAAATACAAACATTAAATGAGGAAATGGTGGTAATTGAATGA

Upstream 100 bases:

>100_bases
ATAGATAGGGTAACTAAGCATGCAAAAAATCTAGTTATGCTAGTGAGAGATGGAAGAAATGCACTAACTCCTTATGCGGG
GAAAGGATTAAGACAGGGGT

Downstream 100 bases:

>100_bases
AAATTATGCAAATAAATTTAGTAGACTATAAAGAATGGACTGAGAGTCTAGGGTATGATAGAGAGTGGAAAATTCAAAAT
TTTCAGCACGGTTTTTTATC

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKMPDQSINLAIVVAEFNYDITYLMLQRAIAHAKFLGANVKVVFKVPGSYDMAIAVKELLKRDDIDAVVTLGAVIKGETK
HDEIVATQTARKILDLSVEYGKPVTLGIIGHGVTHEQAVERIEEYSTRAVEAAIKLAKRLRELRKIQTLNEEMVVIE

Sequences:

>Translated_157_residues
MKMPDQSINLAIVVAEFNYDITYLMLQRAIAHAKFLGANVKVVFKVPGSYDMAIAVKELLKRDDIDAVVTLGAVIKGETK
HDEIVATQTARKILDLSVEYGKPVTLGIIGHGVTHEQAVERIEEYSTRAVEAAIKLAKRLRELRKIQTLNEEMVVIE
>Mature_157_residues
MKMPDQSINLAIVVAEFNYDITYLMLQRAIAHAKFLGANVKVVFKVPGSYDMAIAVKELLKRDDIDAVVTLGAVIKGETK
HDEIVATQTARKILDLSVEYGKPVTLGIIGHGVTHEQAVERIEEYSTRAVEAAIKLAKRLRELRKIQTLNEEMVVIE

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=149, Percent_Identity=32.8859060402685, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_SULTO (Q975M5)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376266.1
- ProteinModelPortal:   Q975M5
- SMR:   Q975M5
- GeneID:   1458319
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0394
- NMPDR:   fig|273063.1.peg.434
- HOGENOM:   HBG311126
- OMA:   AVIQGAT
- ProtClustDB:   PRK00061
- BioCyc:   STOK273063:ST0394-MONOMER
- BRENDA:   2.5.1.9
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 17502; Mature: 17502

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMPDQSINLAIVVAEFNYDITYLMLQRAIAHAKFLGANVKVVFKVPGSYDMAIAVKELL
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHH
KRDDIDAVVTLGAVIKGETKHDEIVATQTARKILDLSVEYGKPVTLGIIGHGVTHEQAVE
HHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHH
RIEEYSTRAVEAAIKLAKRLRELRKIQTLNEEMVVIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MKMPDQSINLAIVVAEFNYDITYLMLQRAIAHAKFLGANVKVVFKVPGSYDMAIAVKELL
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHH
KRDDIDAVVTLGAVIKGETKHDEIVATQTARKILDLSVEYGKPVTLGIIGHGVTHEQAVE
HHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHH
RIEEYSTRAVEAAIKLAKRLRELRKIQTLNEEMVVIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479