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The map label for this gene is gch3

Identifier: 15920598

GI number: 15920598

Start: 406906

End: 407583

Strand: Direct

Name: gch3

Synonym: ST0395

Alternate gene names: 15920598

Gene position: 406906-407583 (Clockwise)

Preceding gene: 15920597

Following gene: 15920599

Centisome position: 15.1

GC content: 28.76

Gene sequence:

>678_bases
ATGAAAATTATGCAAATAAATTTAGTAGACTATAAAGAATGGACTGAGAGTCTAGGGTATGATAGAGAGTGGAAAATTCA
AAATTTTCAGCACGGTTTTTTATCTAGACTTAATGAAATAGCGGCAGAAATAAATTCATTTATAATAACATACAGATATG
ATAGTTATATAATGTTACTGGATGGTGTCTTAATTGGAAAAAATGATTATATTTTAACTAAAATAAAAGAACTTTCACCA
GTTCCAATAGATATATGTTTTGGATATGGTAAAACTTTACTAGATGCAGAAAGAAATTGTTCCATTAATATGGATAATAT
CTTATTAGCCAAAGATGAAAAAGTGCTTGTGGCTCATTTTGATCTAGATGGATTTTCTAGGAAAAGATTTTTGTTTGATG
CTTACCTAGAAGTTTATAAAATATATAATAAGTTATTTAACTATGCAATGGAACTTGGTGGTTTAGCTTATTATTTTGGT
GGTGATAATATAGGAATCTTCTTAGGGGTTGACAATATTAATAAAGTAATAGAATTAGCGAATTCTTTCCCGAATATGAA
AGTAGGTATAGGAATAGGTAATAATCCGAGAGAGGCTCTAAAGAATGCCGCTGAGGCATTACATATTATAAGAATATATA
GGGATAGGAAGATCGAAATTGTCGACTCTAAAAATTAA

Upstream 100 bases:

>100_bases
AGTATTCCACAAGAGCTGTTGAGGCTGCAATAAAATTGGCTAAGAGGTTAAGAGAACTAAGAAAAATACAAACATTAAAT
GAGGAAATGGTGGTAATTGA

Downstream 100 bases:

>100_bases
TTTAGGTGCTATTTTATCTGGAGAGGAACTAGAATATAAAGAAAGAGTTAATATTGAAATAGATGATAATAAGAGAATTT
TACATATCGGTAATGGTTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKIMQINLVDYKEWTESLGYDREWKIQNFQHGFLSRLNEIAAEINSFIITYRYDSYIMLLDGVLIGKNDYILTKIKELSP
VPIDICFGYGKTLLDAERNCSINMDNILLAKDEKVLVAHFDLDGFSRKRFLFDAYLEVYKIYNKLFNYAMELGGLAYYFG
GDNIGIFLGVDNINKVIELANSFPNMKVGIGIGNNPREALKNAAEALHIIRIYRDRKIEIVDSKN

Sequences:

>Translated_225_residues
MKIMQINLVDYKEWTESLGYDREWKIQNFQHGFLSRLNEIAAEINSFIITYRYDSYIMLLDGVLIGKNDYILTKIKELSP
VPIDICFGYGKTLLDAERNCSINMDNILLAKDEKVLVAHFDLDGFSRKRFLFDAYLEVYKIYNKLFNYAMELGGLAYYFG
GDNIGIFLGVDNINKVIELANSFPNMKVGIGIGNNPREALKNAAEALHIIRIYRDRKIEIVDSKN
>Mature_225_residues
MKIMQINLVDYKEWTESLGYDREWKIQNFQHGFLSRLNEIAAEINSFIITYRYDSYIMLLDGVLIGKNDYILTKIKELSP
VPIDICFGYGKTLLDAERNCSINMDNILLAKDEKVLVAHFDLDGFSRKRFLFDAYLEVYKIYNKLFNYAMELGGLAYYFG
GDNIGIFLGVDNINKVIELANSFPNMKVGIGIGNNPREALKNAAEALHIIRIYRDRKIEIVDSKN

Specific function: Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity

COG id: COG2429

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal-type GTP cyclohydrolase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCH3_SULTO (Q975M4)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376267.1
- ProteinModelPortal:   Q975M4
- SMR:   Q975M4
- GeneID:   1458320
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0395
- NMPDR:   fig|273063.1.peg.435
- HOGENOM:   HBG553700
- OMA:   DREWKIQ
- ProtClustDB:   CLSK802708
- BioCyc:   STOK273063:ST0395-MONOMER
- BRENDA:   3.5.4.29
- HAMAP:   MF_00608
- InterPro:   IPR007839
- PIRSF:   PIRSF009265
- ProDom:   PD313320

Pfam domain/function: PF05165 GGDN

EC number: =3.5.4.29

Molecular weight: Translated: 25964; Mature: 25964

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIMQINLVDYKEWTESLGYDREWKIQNFQHGFLSRLNEIAAEINSFIITYRYDSYIMLL
CEEEEEEEECHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHEEEEEEECCEEEEE
DGVLIGKNDYILTKIKELSPVPIDICFGYGKTLLDAERNCSINMDNILLAKDEKVLVAHF
CCEEECCCCEEEEEHHHCCCCCEEEEECCCCHHHCCCCCCCCCCCCEEEECCCEEEEEEE
DLDGFSRKRFLFDAYLEVYKIYNKLFNYAMELGGLAYYFGGDNIGIFLGVDNINKVIELA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEECHHHHHHHHH
NSFPNMKVGIGIGNNPREALKNAAEALHIIRIYRDRKIEIVDSKN
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEECCCEEEEEECCC
>Mature Secondary Structure
MKIMQINLVDYKEWTESLGYDREWKIQNFQHGFLSRLNEIAAEINSFIITYRYDSYIMLL
CEEEEEEEECHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHEEEEEEECCEEEEE
DGVLIGKNDYILTKIKELSPVPIDICFGYGKTLLDAERNCSINMDNILLAKDEKVLVAHF
CCEEECCCCEEEEEHHHCCCCCEEEEECCCCHHHCCCCCCCCCCCCEEEECCCEEEEEEE
DLDGFSRKRFLFDAYLEVYKIYNKLFNYAMELGGLAYYFGGDNIGIFLGVDNINKVIELA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEECHHHHHHHHH
NSFPNMKVGIGIGNNPREALKNAAEALHIIRIYRDRKIEIVDSKN
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479