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The map label for this gene is ribD [C]

Identifier: 15920477

GI number: 15920477

Start: 303296

End: 303937

Strand: Direct

Name: ribD [C]

Synonym: ST0285

Alternate gene names: 15920477

Gene position: 303296-303937 (Clockwise)

Preceding gene: 15920476

Following gene: 15920481

Centisome position: 11.26

GC content: 28.66

Gene sequence:

>642_bases
ATGAGACCCTATATTATAATATTCAGTACTACTACTATAGATGGTAGAATTGCCTCAAAAGACTATTATAGTGAACTAAG
CTGTCCTTACGATAAAATGAGATTACATATTTTAAGAACTGAAGTTGATGCTGTATTGGTTGGTTCTAATACTGTAAGGA
TAGATAATCCTAAGCTTTTAGTTAAGTATGCTAAGGGAAGAAATCCTGTTAGAGTTACAATAAGTGAGAGCTTAAATTTT
GATCCTAATCTAAATATATTTAGTGTACCTCCTGATACAATAATTTATACTACTTACCAAGCTTATCTAAGGAATGAGGA
TAAAGCAAATGAATTAAAGAAAAAAGGAGTAAAAATAAGAGTTTTAGAAAAACTTTCATCTTGTATAATTGCAGAAGACT
TATACAATTTAGGAGTAAAAAGAATTCTAATTGAAGGAGGAGGAAGAACTATATGGAATTTTATAAAGGATAATTGCTTT
GATGAGATTAGGATAACAATATCTCCTAAAATTTTCGGAAATGGTGTTTCAGTAGTAAATGGAGAAGGATTCAAAGGAAT
AGAAGCACCAGAGCTTAAACTTGTAGATTGTAAAATATGTGAATGTAAAAAAGAAATTCATTTAAGATATATGAGATTAT
AA

Upstream 100 bases:

>100_bases
TAGACTGCTGTTTACTCTGCAACATAAGAAGTAAATGTGAGCTTAGGGTTTGGTTTCATGACCTAGTGCCTATAATAAGT
GTTAAAGGGAAAATTTCAAA

Downstream 100 bases:

>100_bases
GAAGGGTTTGTATGTTAACTGGTATATTTCTCCTTGCTCAAGTCTTGTTGCATTTCTCTTGTATTTCATTGCATCTCCAA
TACTATCTTCTCCGTGCATC

Product: 5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: HTP reductase [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MRPYIIIFSTTTIDGRIASKDYYSELSCPYDKMRLHILRTEVDAVLVGSNTVRIDNPKLLVKYAKGRNPVRVTISESLNF
DPNLNIFSVPPDTIIYTTYQAYLRNEDKANELKKKGVKIRVLEKLSSCIIAEDLYNLGVKRILIEGGGRTIWNFIKDNCF
DEIRITISPKIFGNGVSVVNGEGFKGIEAPELKLVDCKICECKKEIHLRYMRL

Sequences:

>Translated_213_residues
MRPYIIIFSTTTIDGRIASKDYYSELSCPYDKMRLHILRTEVDAVLVGSNTVRIDNPKLLVKYAKGRNPVRVTISESLNF
DPNLNIFSVPPDTIIYTTYQAYLRNEDKANELKKKGVKIRVLEKLSSCIIAEDLYNLGVKRILIEGGGRTIWNFIKDNCF
DEIRITISPKIFGNGVSVVNGEGFKGIEAPELKLVDCKICECKKEIHLRYMRL
>Mature_213_residues
MRPYIIIFSTTTIDGRIASKDYYSELSCPYDKMRLHILRTEVDAVLVGSNTVRIDNPKLLVKYAKGRNPVRVTISESLNF
DPNLNIFSVPPDTIIYTTYQAYLRNEDKANELKKKGVKIRVLEKLSSCIIAEDLYNLGVKRILIEGGGRTIWNFIKDNCF
DEIRITISPKIFGNGVSVVNGEGFKGIEAPELKLVDCKICECKKEIHLRYMRL

Specific function: Converts 2,5-Diamino-6-(Ribosylamino)-4(3h)-Pyrimidinone 5'-Phosphate Into 5-Amino-6-(Ribosylamino)-2,4(1h,3h)- Pyrimidinedione 5'-Phosphate. [C]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTP reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004794
- InterPro:   IPR006401
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF01872 RibD_C [H]

EC number: =1.1.1.193 [H]

Molecular weight: Translated: 24312; Mature: 24312

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPYIIIFSTTTIDGRIASKDYYSELSCPYDKMRLHILRTEVDAVLVGSNTVRIDNPKLL
CCCEEEEEEEEEECCEEECCHHHHHCCCCHHHHEEEEEEEEEEEEEECCCEEEECCCEEE
VKYAKGRNPVRVTISESLNFDPNLNIFSVPPDTIIYTTYQAYLRNEDKANELKKKGVKIR
EEECCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEEHHHHHCCCCHHHHHHHCCCEEE
VLEKLSSCIIAEDLYNLGVKRILIEGGGRTIWNFIKDNCFDEIRITISPKIFGNGVSVVN
EHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCEEEEEEECCEEECCCEEEEE
GEGFKGIEAPELKLVDCKICECKKEIHLRYMRL
CCCCCCCCCCCEEEEECHHHHHHHHHCEEEECC
>Mature Secondary Structure
MRPYIIIFSTTTIDGRIASKDYYSELSCPYDKMRLHILRTEVDAVLVGSNTVRIDNPKLL
CCCEEEEEEEEEECCEEECCHHHHHCCCCHHHHEEEEEEEEEEEEEECCCEEEECCCEEE
VKYAKGRNPVRVTISESLNFDPNLNIFSVPPDTIIYTTYQAYLRNEDKANELKKKGVKIR
EEECCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEEHHHHHCCCCHHHHHHHCCCEEE
VLEKLSSCIIAEDLYNLGVKRILIEGGGRTIWNFIKDNCFDEIRITISPKIFGNGVSVVN
EHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCEEEEEEECCEEECCCEEEEE
GEGFKGIEAPELKLVDCKICECKKEIHLRYMRL
CCCCCCCCCCCEEEEECHHHHHHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726 [H]