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The map label for this gene is infB

Identifier: 15920469

GI number: 15920469

Start: 296962

End: 298770

Strand: Direct

Name: infB

Synonym: ST0279

Alternate gene names: 15920469

Gene position: 296962-298770 (Clockwise)

Preceding gene: 15920460

Following gene: 15920472

Centisome position: 11.02

GC content: 33.5

Gene sequence:

>1809_bases
ATGTCTCAACAGTTACAAAGTAGAAGACTTAGACAACCTATTGTAGTGGTTTTAGGCCATGTAGATCACGGTAAAACAAC
ATTATTAGATAAAATTAGAGGAACTGCAGTAGTAAAAAAGGAACCAGGGGAAATGACTCAAGAAGTAGGAGCTAGCTTCG
TTCCTACGAGTGTAATAGAGAAAATAGCAGAACCATTGAAAAAGACATTTCCAATTAAACTTGAAATACCTGGATTACTC
TTTATTGACACTCCAGGGCATGAACTATTTAGTAATCTAAGAAGAAGAGGGGGGAGTGTTGCAGATATTGCTATTCTTGT
CGTAGATGTAGTAGAAGGGTTTCAAAAACAAACTTATGAATCCTTAGAGATATTAAGAAGTAGAAAAGTTCCTTTCTTAG
TGGCCGCAAATAAAATTGACAGAATACCTGGCTGGAAACCAATAGATACTTATTCCTTCTTAGAAAGTATAAAAAGCCAA
AGAAAAGATGTACAAACTCAACTAGATAATTACGTATATAGGCTTGTAGGACAATTAGCAGAATTAGGCTTCAATGCAGA
TAGGTTCGATCGTATAAGAGATTTCACTAAAACAGTTGCAATAGTACCTGTTTCAGCTAAGACAGGCGAAGGAATAGCTG
AATTACTTGCTCTACTTGCTGGATTAACACAGAATTATATGAAAACAAAATTAAGATTTGCCGAAGGACCGGCTAAAGGT
GTTATATTAGAGGTAAAAGAATTACAAGGGCTCGGATATACTATTGATGTTATTATATACGATGGGATCTTAAAGAAGAA
TGATACAATTATAATTGGGGGTCTAAACGGGCCAATTGTAACAAAGGTAAGGTCAATTCTTGTACCAAAGCCTTTGCAAG
ACATCAAAGTAGTTAAGACAGACTTAACACAAATTGATGAAGTTTATGCTGCTGCAGGTGTTAAGATTTATGCACCAGAA
CTCGAAAATGCATTAGCAGGTTCTCCGTTATTTGTAGCAGAGAACGAGCAACAAATTGAAGAATACAAGAAAATTATACA
AGAAGAAATAGCTAGTGTAAAATATTACAATGCAAACATAGCAGGTATTGTTGTTAAAGCTGATAGTTTAGGAAGTTTAG
AAGCTATAGTTGAAGGACTAAAACAAAAGAACATTCCGATTAGATTAGCAGATATAGGTCCTATAACAAAAAAAGATATA
ACTGAAGCTGAACTTACTTTACAAGAAGCAAAAGAATACGGAATTATAGCCGCATTTAGAGTAAAACCATTACAAGGCAT
AGAAGTCCCAAATAACATTAAGTTAATTTACAGCGAAATAATATACCAATTAATAGATGATATAGAGAAGTATATAACAG
AAGTAAGAGAAAGTGAAAAGAGAAGAACTCTAGATTCTTTAATTCTTCCAGGCAAATTTAGGTTAATACCAGGTTATGTA
TTCCGTAGAAGTGATCCAGTAATAGTAGGTGTTGAAGTGCTAGGAGGAATAATAAGGCCAAAGTTTCCAGTTATGAAAAA
AGATGGTAAAAGAGTGGGTGAGATACTTCAAATTCAAGATAATAAAAAAAGTGTAGATAGGGCTACTAAAGGAATGGAAG
TAGCTGTTTCTATAAAGGGAAATATAATGGTAGGAAGACAAATTGATGAAGGAGAAATACTCTACACTGATGTACCAAAG
GAAGATTTAGAGATACTATTAACCAAATATAAAGATATAATCACAGATGATATGAAAGAAGTTATAAAGGAAATAATTAA
TATAAAAAGAGTTAATGACCCTACATATGCACTTGGGCTAAAGGTGTAA

Upstream 100 bases:

>100_bases
AATTCACTCAATGTAATAACACCAGTATCTTTACTAAATATAAGATTAAATTTTTTGAGCATGAAATAGATATCAATGTG
GTTTTAGTTGGTGAAAGATT

Downstream 100 bases:

>100_bases
CTAGCTCTTCTTCTTTGAAAAATATACTCATTTCTCTTTTTGCCTTTTCTTCACTATCTGAAGCGTGTATAACATTTTCT
GCTTTACTTAAGGCATAATC

Product: translation initiation factor IF-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 601

Protein sequence:

>602_residues
MSQQLQSRRLRQPIVVVLGHVDHGKTTLLDKIRGTAVVKKEPGEMTQEVGASFVPTSVIEKIAEPLKKTFPIKLEIPGLL
FIDTPGHELFSNLRRRGGSVADIAILVVDVVEGFQKQTYESLEILRSRKVPFLVAANKIDRIPGWKPIDTYSFLESIKSQ
RKDVQTQLDNYVYRLVGQLAELGFNADRFDRIRDFTKTVAIVPVSAKTGEGIAELLALLAGLTQNYMKTKLRFAEGPAKG
VILEVKELQGLGYTIDVIIYDGILKKNDTIIIGGLNGPIVTKVRSILVPKPLQDIKVVKTDLTQIDEVYAAAGVKIYAPE
LENALAGSPLFVAENEQQIEEYKKIIQEEIASVKYYNANIAGIVVKADSLGSLEAIVEGLKQKNIPIRLADIGPITKKDI
TEAELTLQEAKEYGIIAAFRVKPLQGIEVPNNIKLIYSEIIYQLIDDIEKYITEVRESEKRRTLDSLILPGKFRLIPGYV
FRRSDPVIVGVEVLGGIIRPKFPVMKKDGKRVGEILQIQDNKKSVDRATKGMEVAVSIKGNIMVGRQIDEGEILYTDVPK
EDLEILLTKYKDIITDDMKEVIKEIINIKRVNDPTYALGLKV

Sequences:

>Translated_602_residues
MSQQLQSRRLRQPIVVVLGHVDHGKTTLLDKIRGTAVVKKEPGEMTQEVGASFVPTSVIEKIAEPLKKTFPIKLEIPGLL
FIDTPGHELFSNLRRRGGSVADIAILVVDVVEGFQKQTYESLEILRSRKVPFLVAANKIDRIPGWKPIDTYSFLESIKSQ
RKDVQTQLDNYVYRLVGQLAELGFNADRFDRIRDFTKTVAIVPVSAKTGEGIAELLALLAGLTQNYMKTKLRFAEGPAKG
VILEVKELQGLGYTIDVIIYDGILKKNDTIIIGGLNGPIVTKVRSILVPKPLQDIKVVKTDLTQIDEVYAAAGVKIYAPE
LENALAGSPLFVAENEQQIEEYKKIIQEEIASVKYYNANIAGIVVKADSLGSLEAIVEGLKQKNIPIRLADIGPITKKDI
TEAELTLQEAKEYGIIAAFRVKPLQGIEVPNNIKLIYSEIIYQLIDDIEKYITEVRESEKRRTLDSLILPGKFRLIPGYV
FRRSDPVIVGVEVLGGIIRPKFPVMKKDGKRVGEILQIQDNKKSVDRATKGMEVAVSIKGNIMVGRQIDEGEILYTDVPK
EDLEILLTKYKDIITDDMKEVIKEIINIKRVNDPTYALGLKV
>Mature_601_residues
SQQLQSRRLRQPIVVVLGHVDHGKTTLLDKIRGTAVVKKEPGEMTQEVGASFVPTSVIEKIAEPLKKTFPIKLEIPGLLF
IDTPGHELFSNLRRRGGSVADIAILVVDVVEGFQKQTYESLEILRSRKVPFLVAANKIDRIPGWKPIDTYSFLESIKSQR
KDVQTQLDNYVYRLVGQLAELGFNADRFDRIRDFTKTVAIVPVSAKTGEGIAELLALLAGLTQNYMKTKLRFAEGPAKGV
ILEVKELQGLGYTIDVIIYDGILKKNDTIIIGGLNGPIVTKVRSILVPKPLQDIKVVKTDLTQIDEVYAAAGVKIYAPEL
ENALAGSPLFVAENEQQIEEYKKIIQEEIASVKYYNANIAGIVVKADSLGSLEAIVEGLKQKNIPIRLADIGPITKKDIT
EAELTLQEAKEYGIIAAFRVKPLQGIEVPNNIKLIYSEIIYQLIDDIEKYITEVRESEKRRTLDSLILPGKFRLIPGYVF
RRSDPVIVGVEVLGGIIRPKFPVMKKDGKRVGEILQIQDNKKSVDRATKGMEVAVSIKGNIMVGRQIDEGEILYTDVPKE
DLEILLTKYKDIITDDMKEVIKEIINIKRVNDPTYALGLKV

Specific function: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2

COG id: COG0532

COG function: function code J; Translation initiation factor 2 (IF-2; GTPase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-2 family

Homologues:

Organism=Homo sapiens, GI84043963, Length=602, Percent_Identity=37.8737541528239, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI53729339, Length=263, Percent_Identity=32.6996197718631, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI53729337, Length=263, Percent_Identity=32.6996197718631, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1789559, Length=558, Percent_Identity=27.2401433691756, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI212656558, Length=578, Percent_Identity=35.9861591695502, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI71994658, Length=608, Percent_Identity=25.1644736842105, Blast_Score=108, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6319282, Length=586, Percent_Identity=38.0546075085324, Blast_Score=362, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6324550, Length=584, Percent_Identity=25.1712328767123, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24656849, Length=584, Percent_Identity=36.8150684931507, Blast_Score=380, Evalue=1e-105,
Organism=Drosophila melanogaster, GI28572034, Length=277, Percent_Identity=31.7689530685921, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI160714833, Length=87, Percent_Identity=43.6781609195402, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: 1150 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): IF2P_SULTO (Q976A1)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376138.1
- ProteinModelPortal:   Q976A1
- SMR:   Q976A1
- GeneID:   1458181
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0279
- NMPDR:   fig|273063.1.peg.306
- HOGENOM:   HBG635083
- OMA:   SPLRIVP
- ProtClustDB:   PRK04004
- BioCyc:   STOK273063:ST0279-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00100_A
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR004544
- InterPro:   IPR015760
- InterPro:   IPR023115
- InterPro:   IPR004161
- InterPro:   IPR009000
- Gene3D:   G3DSA:3.40.50.10050
- PANTHER:   PTHR23115:SF41
- PRINTS:   PR00315
- TIGRFAMs:   TIGR00491
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2; PF11987 IF-2; SSF52156 TIF_IF2_dom3; SSF50447 Translat_factor

EC number: NA

Molecular weight: Translated: 67131; Mature: 67000

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS01176 IF2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQLQSRRLRQPIVVVLGHVDHGKTTLLDKIRGTAVVKKEPGEMTQEVGASFVPTSVIE
CCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCEEEECCCCHHHHHCCCCCCCHHHHH
KIAEPLKKTFPIKLEIPGLLFIDTPGHELFSNLRRRGGSVADIAILVVDVVEGFQKQTYE
HHHHHHHHCCCEEEECCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SLEILRSRKVPFLVAANKIDRIPGWKPIDTYSFLESIKSQRKDVQTQLDNYVYRLVGQLA
HHHHHHHCCCCEEEECCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELGFNADRFDRIRDFTKTVAIVPVSAKTGEGIAELLALLAGLTQNYMKTKLRFAEGPAKG
HCCCCHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VILEVKELQGLGYTIDVIIYDGILKKNDTIIIGGLNGPIVTKVRSILVPKPLQDIKVVKT
EEEEEEHHCCCCEEEEEEEEECEECCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHH
DLTQIDEVYAAAGVKIYAPELENALAGSPLFVAENEQQIEEYKKIIQEEIASVKYYNANI
HHHHHHHHHHHCCCEEECCCHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHEEEECCCE
AGIVVKADSLGSLEAIVEGLKQKNIPIRLADIGPITKKDITEAELTLQEAKEYGIIAAFR
EEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEEE
VKPLQGIEVPNNIKLIYSEIIYQLIDDIEKYITEVRESEKRRTLDSLILPGKFRLIPGYV
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEE
FRRSDPVIVGVEVLGGIIRPKFPVMKKDGKRVGEILQIQDNKKSVDRATKGMEVAVSIKG
EECCCCEEEEHHHHCHHHCCCCCCCCCCCHHHHHHEEECCCHHHHHHHCCCCEEEEEEEC
NIMVGRQIDEGEILYTDVPKEDLEILLTKYKDIITDDMKEVIKEIINIKRVNDPTYALGL
CEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
KV
CC
>Mature Secondary Structure 
SQQLQSRRLRQPIVVVLGHVDHGKTTLLDKIRGTAVVKKEPGEMTQEVGASFVPTSVIE
CCHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCEEEECCCCHHHHHCCCCCCCHHHHH
KIAEPLKKTFPIKLEIPGLLFIDTPGHELFSNLRRRGGSVADIAILVVDVVEGFQKQTYE
HHHHHHHHCCCEEEECCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SLEILRSRKVPFLVAANKIDRIPGWKPIDTYSFLESIKSQRKDVQTQLDNYVYRLVGQLA
HHHHHHHCCCCEEEECCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELGFNADRFDRIRDFTKTVAIVPVSAKTGEGIAELLALLAGLTQNYMKTKLRFAEGPAKG
HCCCCHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VILEVKELQGLGYTIDVIIYDGILKKNDTIIIGGLNGPIVTKVRSILVPKPLQDIKVVKT
EEEEEEHHCCCCEEEEEEEEECEECCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHH
DLTQIDEVYAAAGVKIYAPELENALAGSPLFVAENEQQIEEYKKIIQEEIASVKYYNANI
HHHHHHHHHHHCCCEEECCCHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHEEEECCCE
AGIVVKADSLGSLEAIVEGLKQKNIPIRLADIGPITKKDITEAELTLQEAKEYGIIAAFR
EEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEEE
VKPLQGIEVPNNIKLIYSEIIYQLIDDIEKYITEVRESEKRRTLDSLILPGKFRLIPGYV
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEE
FRRSDPVIVGVEVLGGIIRPKFPVMKKDGKRVGEILQIQDNKKSVDRATKGMEVAVSIKG
EECCCCEEEEHHHHCHHHCCCCCCCCCCCHHHHHHEEECCCHHHHHHHCCCCEEEEEEEC
NIMVGRQIDEGEILYTDVPKEDLEILLTKYKDIITDDMKEVIKEIINIKRVNDPTYALGL
CEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
KV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479