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The map label for this gene is groES [H]

Identifier: 161723842

GI number: 161723842

Start: 911732

End: 912019

Strand: Reverse

Name: groES [H]

Synonym: RC0969

Alternate gene names: 161723842

Gene position: 912019-911732 (Counterclockwise)

Preceding gene: 15892893

Following gene: 15892891

Centisome position: 71.88

GC content: 33.68

Gene sequence:

>288_bases
ATGTCTTTTAAACCATTACATGATAGAATTGCAATAAAGCCTATCGAACAAGAAGAAAAAACTAAAGGTGGAATTATTAT
TCCGGATACTGTAAAAGAAAAGCCGATGCAAGGTGAAATAGTAGCCGTAGGTAATGGTATTCGTAATGAAAAAGGCGAAA
TTCATCCTTTAGAGCTAAAAGTAGGCGATAAAGTTTTATACGGTAAATGGGCAGGCACCGAAATTGAAATTAAAGGCACA
AAACTGATCGTTATGAAAGAAAGCGACGTATTTGGTATTATTAATTAA

Upstream 100 bases:

>100_bases
TAGACCTCTAATAAAAAAATTTTTATTCTTGCCCCTTGAACTAACAAAAATAAAATATATATAGTATGTACATTTAAAGA
TTTAATAATTGGAGGTTAAA

Downstream 100 bases:

>100_bases
TTATTTGTTTTTAAGGAGAAATTAAATATGGCAACAAAACTTATTAAACACGGCTCAAAAGCTCGTGAGCAAATGTTAGA
AGGCATTGATATACTTGCAG

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 95; Mature: 94

Protein sequence:

>95_residues
MSFKPLHDRIAIKPIEQEEKTKGGIIIPDTVKEKPMQGEIVAVGNGIRNEKGEIHPLELKVGDKVLYGKWAGTEIEIKGT
KLIVMKESDVFGIIN

Sequences:

>Translated_95_residues
MSFKPLHDRIAIKPIEQEEKTKGGIIIPDTVKEKPMQGEIVAVGNGIRNEKGEIHPLELKVGDKVLYGKWAGTEIEIKGT
KLIVMKESDVFGIIN
>Mature_94_residues
SFKPLHDRIAIKPIEQEEKTKGGIIIPDTVKEKPMQGEIVAVGNGIRNEKGEIHPLELKVGDKVLYGKWAGTEIEIKGTK
LIVMKESDVFGIIN

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=90, Percent_Identity=37.7777777777778, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=41.0526315789474, Blast_Score=79, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=38.2978723404255, Blast_Score=85, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21356029, Length=91, Percent_Identity=38.4615384615385, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358317, Length=90, Percent_Identity=38.8888888888889, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10537; Mature: 10405

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKPLHDRIAIKPIEQEEKTKGGIIIPDTVKEKPMQGEIVAVGNGIRNEKGEIHPLELK
CCCCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEE
VGDKVLYGKWAGTEIEIKGTKLIVMKESDVFGIIN
ECCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC
>Mature Secondary Structure 
SFKPLHDRIAIKPIEQEEKTKGGIIIPDTVKEKPMQGEIVAVGNGIRNEKGEIHPLELK
CCCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEE
VGDKVLYGKWAGTEIEIKGTKLIVMKESDVFGIIN
ECCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA