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The map label for this gene is pntAB [H]

Identifier: 15893256

GI number: 15893256

Start: 1237275

End: 1237673

Strand: Reverse

Name: pntAB [H]

Synonym: RC1333

Alternate gene names: 15893256

Gene position: 1237673-1237275 (Counterclockwise)

Preceding gene: 15893257

Following gene: 15893254

Centisome position: 97.55

GC content: 36.34

Gene sequence:

>399_bases
ATGAATCAATTACCGACGATGGCTAAACAGGCTGCTGAAATTGCCCATAATACCCAAGAATTATCAGATAAATTAAAAGA
TTTGGTAATAGATACTAGTTGGCAAACAAACACAAGTACTATAGATCCGCTAGTATTTGCTATAACTATTTTTGTATTAG
CTTCTTTTGTGGGCTATTATGTTGTGTGGAAAGTAACGCCTGCACTCCATACTCCGCTTATGTCTATTACTAACGCTATT
TCAGGTATTATAGTTCTTAGTTCTATGATTGCTGCAAGTAGCTCTGCTTTTGGGTTTCCCGGTCTACTAGGGTATTTTGC
AACGCTGCTTGCTTCTATAAATATCTTCGGCGGATTTATAGTAACAAAAAGAATGCTCGAGATGTTTAAGAAGAAGTAA

Upstream 100 bases:

>100_bases
CCTATGCATTGCAAGACGGTAAGTTTAATATGGATGATGCGTTAGTACGTGAGATGTTGATTACTAAAGACGGAAAAATT
GTGAGTGAGAAATTAAATAT

Downstream 100 bases:

>100_bases
TTAATAATGTCATACCTGCGTTGTTGATACCCAAATCGTCATTGCAAGGAGCAGGGGGTGTTGCATGGATCGAAAAACCT
ACTCGATGTCGTTCCTGCGT

Product: NAD(p) transhydrogenase subunit alpha

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Pyridine nucleotide transhydrogenase subunit alpha 2 [H]

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MNQLPTMAKQAAEIAHNTQELSDKLKDLVIDTSWQTNTSTIDPLVFAITIFVLASFVGYYVVWKVTPALHTPLMSITNAI
SGIIVLSSMIAASSSAFGFPGLLGYFATLLASINIFGGFIVTKRMLEMFKKK

Sequences:

>Translated_132_residues
MNQLPTMAKQAAEIAHNTQELSDKLKDLVIDTSWQTNTSTIDPLVFAITIFVLASFVGYYVVWKVTPALHTPLMSITNAI
SGIIVLSSMIAASSSAFGFPGLLGYFATLLASINIFGGFIVTKRMLEMFKKK
>Mature_132_residues
MNQLPTMAKQAAEIAHNTQELSDKLKDLVIDTSWQTNTSTIDPLVFAITIFVLASFVGYYVVWKVTPALHTPLMSITNAI
SGIIVLSSMIAASSSAFGFPGLLGYFATLLASINIFGGFIVTKRMLEMFKKK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=90, Percent_Identity=47.7777777777778, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI122939153, Length=90, Percent_Identity=47.7777777777778, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1787887, Length=83, Percent_Identity=60.2409638554217, Blast_Score=102, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17550456, Length=90, Percent_Identity=50, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 14393; Mature: 14393

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLPTMAKQAAEIAHNTQELSDKLKDLVIDTSWQTNTSTIDPLVFAITIFVLASFVGYY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VVWKVTPALHTPLMSITNAISGIIVLSSMIAASSSAFGFPGLLGYFATLLASINIFGGFI
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VTKRMLEMFKKK
HHHHHHHHHHCC
>Mature Secondary Structure
MNQLPTMAKQAAEIAHNTQELSDKLKDLVIDTSWQTNTSTIDPLVFAITIFVLASFVGYY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VVWKVTPALHTPLMSITNAISGIIVLSSMIAASSSAFGFPGLLGYFATLLASINIFGGFI
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VTKRMLEMFKKK
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9823893; 8662004 [H]