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The map label for this gene is udg [H]

Identifier: 15893135

GI number: 15893135

Start: 1109376

End: 1110674

Strand: Reverse

Name: udg [H]

Synonym: RC1212

Alternate gene names: 15893135

Gene position: 1110674-1109376 (Counterclockwise)

Preceding gene: 15893152

Following gene: 15893134

Centisome position: 87.54

GC content: 30.48

Gene sequence:

>1299_bases
ATGAATATTACATTTATCGGTAGCGGATATGTGGGATTAGTCTCAGGTATTATTATGGGCTATTTAGGTCATAATGTTAC
TTGTCTTGATAATGATGAGGTTAAAATATCCAAATTAAATAAGCAAATATTACCGATTTATGAAGCTAAACTTGATGAGT
ATCTTAAGCAAGCTTTAGAATCTGATAGGTTAAAATTTACAAATATTTATAATAATGAACTTCAAAATGCTGATGCAATA
TTTATTACGGTCGGTACACCTTCAAAAGGGTTGGGAGAAGCGGATTTAAAATATGTTTATGATGCTATTGATAAAGTTTT
CGAGCATATAAATAAAGATTGTTTAATAGTCATAAAATCTACCGTTCCGCCGGGTAGTTGCAGTAATATTATAGCTTATT
TAAAATCAAGAGGCTTTTCATTTAATGTTGCTTCTAATCCTGAGTTTTTAAGAGAGGGTAGTGCGGTAGAAGATTTTTTA
TATCCTGATCGTATAGTTATCGGTGTAAATAATAAAGAATCAGAGGCAATATTGCGAAAAATTTATGCACCTTTACAAGG
TGTAAAGTTTGTGGTTACTGATTTAGTGACGAGCGAACTTATTAAATATGCTTCAAATAGTTTCTTAGCTACCAAAATTG
CTTTTATTAATGAGATGGCTGATTTATGTGAAAAAATCGGCGGTAATATTAAAGATTTATCTAAAGGTGTAGGACTTGAC
CAAAGAATCGGTCAAAATTTTTTAAATGCAGGACCTGGTTTTGGCGGTTCGTGCTTTCCAAAAGATATTCTAGCATTAAA
TAATCTTGTAGAAAATCATCATATAGATTGTAGGATTCTTAAGGCAGTAATTAAAAGTAATAAGCAGCGCCCAAGTAATA
TGGTAGATAAAATAGCTACTTTGTTAGACGGAGATTTAAAAGGTAAAAATATAGCAATTTTAGGCTTAACATATAAAGCA
GGAACAGATGATGTAAGAGCAAGCCCTGCCATCGCAATTGTAAAGATCTTATTAAATAAAGATGTATATGTTAAAGCATT
TGATCCTATCGGTCTTGAAAATGCTAAAAAGAATTTGGAACATAAAAATTTGCTATATTTAGATTCAGCAGTTGACGCCT
GTAAATCAGTAGATATTATAGTTATTGCAACTGAATGGTCAGAATTTAAAGAACTTAATTGGCAAGAAATTTATGATTTA
GTAAAATCGCCGATAATCATTGATTTTAGAAATATACTAGATAATGAAACAATGAAAAAAATCGGTTTTAGATATTATGC
AGTCGGAAGTAAAATTTAG

Upstream 100 bases:

>100_bases
TGAAATTGAGCTTCGTCTATACTACTCTTCATTTATTTGAGGTATACACTTGGAATATAACGTATAATTTAAAAATTTAA
TATAAAAATCACAAAAAATT

Downstream 100 bases:

>100_bases
TCTTGTCGTTAAGGCTTCCGATGTTATTCCCGCGTAGGCGGGAATCCAGGGTAAAGCGAGATAAATCGAGCTTTTAAAAA
GTTTTAAAGTACTGGATTCC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MNITFIGSGYVGLVSGIIMGYLGHNVTCLDNDEVKISKLNKQILPIYEAKLDEYLKQALESDRLKFTNIYNNELQNADAI
FITVGTPSKGLGEADLKYVYDAIDKVFEHINKDCLIVIKSTVPPGSCSNIIAYLKSRGFSFNVASNPEFLREGSAVEDFL
YPDRIVIGVNNKESEAILRKIYAPLQGVKFVVTDLVTSELIKYASNSFLATKIAFINEMADLCEKIGGNIKDLSKGVGLD
QRIGQNFLNAGPGFGGSCFPKDILALNNLVENHHIDCRILKAVIKSNKQRPSNMVDKIATLLDGDLKGKNIAILGLTYKA
GTDDVRASPAIAIVKILLNKDVYVKAFDPIGLENAKKNLEHKNLLYLDSAVDACKSVDIIVIATEWSEFKELNWQEIYDL
VKSPIIIDFRNILDNETMKKIGFRYYAVGSKI

Sequences:

>Translated_432_residues
MNITFIGSGYVGLVSGIIMGYLGHNVTCLDNDEVKISKLNKQILPIYEAKLDEYLKQALESDRLKFTNIYNNELQNADAI
FITVGTPSKGLGEADLKYVYDAIDKVFEHINKDCLIVIKSTVPPGSCSNIIAYLKSRGFSFNVASNPEFLREGSAVEDFL
YPDRIVIGVNNKESEAILRKIYAPLQGVKFVVTDLVTSELIKYASNSFLATKIAFINEMADLCEKIGGNIKDLSKGVGLD
QRIGQNFLNAGPGFGGSCFPKDILALNNLVENHHIDCRILKAVIKSNKQRPSNMVDKIATLLDGDLKGKNIAILGLTYKA
GTDDVRASPAIAIVKILLNKDVYVKAFDPIGLENAKKNLEHKNLLYLDSAVDACKSVDIIVIATEWSEFKELNWQEIYDL
VKSPIIIDFRNILDNETMKKIGFRYYAVGSKI
>Mature_432_residues
MNITFIGSGYVGLVSGIIMGYLGHNVTCLDNDEVKISKLNKQILPIYEAKLDEYLKQALESDRLKFTNIYNNELQNADAI
FITVGTPSKGLGEADLKYVYDAIDKVFEHINKDCLIVIKSTVPPGSCSNIIAYLKSRGFSFNVASNPEFLREGSAVEDFL
YPDRIVIGVNNKESEAILRKIYAPLQGVKFVVTDLVTSELIKYASNSFLATKIAFINEMADLCEKIGGNIKDLSKGVGLD
QRIGQNFLNAGPGFGGSCFPKDILALNNLVENHHIDCRILKAVIKSNKQRPSNMVDKIATLLDGDLKGKNIAILGLTYKA
GTDDVRASPAIAIVKILLNKDVYVKAFDPIGLENAKKNLEHKNLLYLDSAVDACKSVDIIVIATEWSEFKELNWQEIYDL
VKSPIIIDFRNILDNETMKKIGFRYYAVGSKI

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=461, Percent_Identity=32.9718004338395, Blast_Score=229, Evalue=5e-60,
Organism=Homo sapiens, GI296040438, Length=363, Percent_Identity=33.0578512396694, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI296040443, Length=453, Percent_Identity=30.4635761589404, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1788340, Length=363, Percent_Identity=32.5068870523416, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI48994968, Length=415, Percent_Identity=26.9879518072289, Blast_Score=129, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17560350, Length=466, Percent_Identity=34.3347639484979, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI17136908, Length=463, Percent_Identity=34.341252699784, Blast_Score=243, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 47879; Mature: 47879

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITFIGSGYVGLVSGIIMGYLGHNVTCLDNDEVKISKLNKQILPIYEAKLDEYLKQALE
CEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEHHHHCCHHHHHHHHHHHHHHHHHHH
SDRLKFTNIYNNELQNADAIFITVGTPSKGLGEADLKYVYDAIDKVFEHINKDCLIVIKS
CCCEEEEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEC
TVPPGSCSNIIAYLKSRGFSFNVASNPEFLREGSAVEDFLYPDRIVIGVNNKESEAILRK
CCCCCCHHHHHHHHHHCCCEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCCHHHHHHHH
IYAPLQGVKFVVTDLVTSELIKYASNSFLATKIAFINEMADLCEKIGGNIKDLSKGVGLD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCH
QRIGQNFLNAGPGFGGSCFPKDILALNNLVENHHIDCRILKAVIKSNKQRPSNMVDKIAT
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
LLDGDLKGKNIAILGLTYKAGTDDVRASPAIAIVKILLNKDVYVKAFDPIGLENAKKNLE
HHCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCC
HKNLLYLDSAVDACKSVDIIVIATEWSEFKELNWQEIYDLVKSPIIIDFRNILDNETMKK
CCCEEEEHHHHHHHCCCCEEEEEECCHHHHHCCHHHHHHHHHCCEEEEHHHHHCCHHHHH
IGFRYYAVGSKI
HCCEEEECCCCC
>Mature Secondary Structure
MNITFIGSGYVGLVSGIIMGYLGHNVTCLDNDEVKISKLNKQILPIYEAKLDEYLKQALE
CEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEHHHHCCHHHHHHHHHHHHHHHHHHH
SDRLKFTNIYNNELQNADAIFITVGTPSKGLGEADLKYVYDAIDKVFEHINKDCLIVIKS
CCCEEEEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEC
TVPPGSCSNIIAYLKSRGFSFNVASNPEFLREGSAVEDFLYPDRIVIGVNNKESEAILRK
CCCCCCHHHHHHHHHHCCCEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCCHHHHHHHH
IYAPLQGVKFVVTDLVTSELIKYASNSFLATKIAFINEMADLCEKIGGNIKDLSKGVGLD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCH
QRIGQNFLNAGPGFGGSCFPKDILALNNLVENHHIDCRILKAVIKSNKQRPSNMVDKIAT
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
LLDGDLKGKNIAILGLTYKAGTDDVRASPAIAIVKILLNKDVYVKAFDPIGLENAKKNLE
HHCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCC
HKNLLYLDSAVDACKSVDIIVIATEWSEFKELNWQEIYDLVKSPIIIDFRNILDNETMKK
CCCEEEEHHHHHHHCCCCEEEEEECCHHHHHCCHHHHHHHHHCCEEEEHHHHHCCHHHHH
IGFRYYAVGSKI
HCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA