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The map label for this gene is ubiA [H]

Identifier: 15892972

GI number: 15892972

Start: 974337

End: 975185

Strand: Reverse

Name: ubiA [H]

Synonym: RC1049

Alternate gene names: 15892972

Gene position: 975185-974337 (Counterclockwise)

Preceding gene: 15892979

Following gene: 15892970

Centisome position: 76.86

GC content: 31.68

Gene sequence:

>849_bases
ATGCTAATTCTGGACAAACTTTTGCTTACCTTAAAATTAATGCGTGCAGATAAGCTGGTAGCTTATTTGCTGGTTTTTTT
TCCTGCTTTATTTGGGTTACTGCTTGCAAACCCCTCAAGAACGGAGTTAATACATTTATTACCGTTATTTATTTTAGGTA
GTATAACAGCTAGAAGTAGCGGGTGTATTATTAACGATATATTTGATAGAAAATTTGATAAGCATGTCGCAAGGACTAAA
GAGCGACCTTTAGCTAGCAAGGCTTTATCTGTTTCTTATGCTATTTTGATACTCTTTATTCTTAGCGTTATCTCACTTTG
TATTTTGCTACTTTTAAACAAAACAGCTATATATATAGGTTTTTTTGCGGTAATAATGATTAGCCTATACCCGTTAATGA
AACGTATTACTTATTTCCCGCAAATCTTTTTGGGATTTACATTTAAGCTAGGGGCCTTAATAGCTTATGCGGCAGTTCAG
GATACACTTGATATAGCAGCGATTATTATGTATTTAGCATGCTGTTTTTGGGCTATCGGTTATGATACGATTTACGGATA
TATGGATATAAGAGATGATAAGAAAATAGGAGTGAAATCGTTAAGTATATATTTAGAGAACAAGCATTCTAAGCTTTGGC
TTTATATATGTTATATAGGTTTTATATTGTTATTTATTCTAGCAACAAAAATGGCTAACCATAATATCGACTATTTACCT
ATTTTAGCTGCTTTAATTTTACTGATATTACAAGTAGCAACTCTTGATATTGAAAATCCTGCCAATTGTATGACAAGATT
CAGAGCTAATAATTATATCGGATTAGTTTTGAGTATGGTGTTTTATTAA

Upstream 100 bases:

>100_bases
TTTAATTTTTTAGCCATAAAAATCTAGTAGCTTTATTTCGTGGCGTATTTTATCTTAAATTATCTATAATATCCATATTT
ATTTAAATTTAAAGTTTAAT

Downstream 100 bases:

>100_bases
ATTCTTTTCCTAATAACAGTCTTGTTAGGGATTAGATAATGTTCTTGATGTCATTCCTGCGAAAGCAGGAATCCATAAAA
ATAACATTAATATTGCTGTA

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MLILDKLLLTLKLMRADKLVAYLLVFFPALFGLLLANPSRTELIHLLPLFILGSITARSSGCIINDIFDRKFDKHVARTK
ERPLASKALSVSYAILILFILSVISLCILLLLNKTAIYIGFFAVIMISLYPLMKRITYFPQIFLGFTFKLGALIAYAAVQ
DTLDIAAIIMYLACCFWAIGYDTIYGYMDIRDDKKIGVKSLSIYLENKHSKLWLYICYIGFILLFILATKMANHNIDYLP
ILAALILLILQVATLDIENPANCMTRFRANNYIGLVLSMVFY

Sequences:

>Translated_282_residues
MLILDKLLLTLKLMRADKLVAYLLVFFPALFGLLLANPSRTELIHLLPLFILGSITARSSGCIINDIFDRKFDKHVARTK
ERPLASKALSVSYAILILFILSVISLCILLLLNKTAIYIGFFAVIMISLYPLMKRITYFPQIFLGFTFKLGALIAYAAVQ
DTLDIAAIIMYLACCFWAIGYDTIYGYMDIRDDKKIGVKSLSIYLENKHSKLWLYICYIGFILLFILATKMANHNIDYLP
ILAALILLILQVATLDIENPANCMTRFRANNYIGLVLSMVFY
>Mature_282_residues
MLILDKLLLTLKLMRADKLVAYLLVFFPALFGLLLANPSRTELIHLLPLFILGSITARSSGCIINDIFDRKFDKHVARTK
ERPLASKALSVSYAILILFILSVISLCILLLLNKTAIYIGFFAVIMISLYPLMKRITYFPQIFLGFTFKLGALIAYAAVQ
DTLDIAAIIMYLACCFWAIGYDTIYGYMDIRDDKKIGVKSLSIYLENKHSKLWLYICYIGFILLFILATKMANHNIDYLP
ILAALILLILQVATLDIENPANCMTRFRANNYIGLVLSMVFY

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=270, Percent_Identity=34.4444444444444, Blast_Score=164, Evalue=7e-41,
Organism=Escherichia coli, GI1790473, Length=277, Percent_Identity=37.1841155234657, Blast_Score=168, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17553718, Length=270, Percent_Identity=38.5185185185185, Blast_Score=174, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI32565247, Length=270, Percent_Identity=37.037037037037, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17553720, Length=326, Percent_Identity=29.1411042944785, Blast_Score=123, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI32565245, Length=136, Percent_Identity=42.6470588235294, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32565243, Length=161, Percent_Identity=38.5093167701863, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324370, Length=273, Percent_Identity=30.03663003663, Blast_Score=132, Evalue=5e-32,
Organism=Drosophila melanogaster, GI21355567, Length=273, Percent_Identity=35.8974358974359, Blast_Score=169, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 31996; Mature: 31996

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILDKLLLTLKLMRADKLVAYLLVFFPALFGLLLANPSRTELIHLLPLFILGSITARSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
GCIINDIFDRKFDKHVARTKERPLASKALSVSYAILILFILSVISLCILLLLNKTAIYIG
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFAVIMISLYPLMKRITYFPQIFLGFTFKLGALIAYAAVQDTLDIAAIIMYLACCFWAIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDTIYGYMDIRDDKKIGVKSLSIYLENKHSKLWLYICYIGFILLFILATKMANHNIDYLP
HHHHHHHHEECCCCHHCHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ILAALILLILQVATLDIENPANCMTRFRANNYIGLVLSMVFY
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHC
>Mature Secondary Structure
MLILDKLLLTLKLMRADKLVAYLLVFFPALFGLLLANPSRTELIHLLPLFILGSITARSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
GCIINDIFDRKFDKHVARTKERPLASKALSVSYAILILFILSVISLCILLLLNKTAIYIG
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFAVIMISLYPLMKRITYFPQIFLGFTFKLGALIAYAAVQDTLDIAAIIMYLACCFWAIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDTIYGYMDIRDDKKIGVKSLSIYLENKHSKLWLYICYIGFILLFILATKMANHNIDYLP
HHHHHHHHEECCCCHHCHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ILAALILLILQVATLDIENPANCMTRFRANNYIGLVLSMVFY
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA