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The map label for this gene is recG [H]

Identifier: 15892824

GI number: 15892824

Start: 847167

End: 849308

Strand: Reverse

Name: recG [H]

Synonym: RC0901

Alternate gene names: 15892824

Gene position: 849308-847167 (Counterclockwise)

Preceding gene: 15892825

Following gene: 15892814

Centisome position: 66.94

GC content: 34.45

Gene sequence:

>2142_bases
ATGCTAACTATTTTAGAAAAATTCTTATTCTCTTCTGTAAAAACGTTCATCAATATACGTGAAGATACCGTATCTGCTCT
TAAAAGGCTTGGTATTAAAAATATTCGTGATTTATTATTTTATCTACCTGTTTCATATCAAAATAAAATATTATCGCCTA
ATTTAACTGAAGTTAGAGACGGTGACATAATCCAAACAGAAATTGTAGTTGAGAGCATTAATTTACCAAAGAAAAGTAGT
CAGCCTTTAAAAATTACAGCTAGCAATGATACTGGTTCTTTGTTATTAGTGTTTTTTCATAAACCCCCACCGTTTATTTT
TAATAAGCTGCAAGTTGGTACTTCTCATATTATCAGCGGAAAGGTACAATTTTTTGATCATTACTTACAAATTGCGCATC
CTGAATTTATTGTAAATCCTAAACTTGCAAAAGAAATAGAGCCGATTTATTCCCTGACATATTTACTTAGTAACAAGCAG
TTATATTCATATATCATAAAAGCAATAGAGATATTTGAAGAGAAGTGTAAGAGTATAGAAGATAAAGAAGTAAAAGATTA
TTTAGATATTATATTGCAGAATTTGCAAATGTTGCATGTTTTCCATCATTGCGAGGAGGCATGCATGCCGACGAAGCAAT
CCAGTAATGTAAAATTAATAAATTCTAGATTGCCGCAGCCCCTAAAGGGGCTTCACAATGACGATTTATATACTAACGCC
AAAAAACAACTAGCAGCTAAGGAGCTTATCGCTAATCAAATATCTCTTTTAAATGTACGTACGCAAATAAGTAGAAGACA
AGGTAATATTTACCCTAAAGCTGTATCTATTCAAGCAAATATATTAAATGAGCTAGGATTTGAGTTAACCTCTTATCAAA
AGCAAGTCATAGAAGAAATAGAGTGTGATCAAAGCGATAAAATAGAAATGATGAGATTGTTGCAAGGCGATGTTGGCTCC
GGTAAAACTTTGGTAGCTCTGCTGACGATGGTAAATGTGGTAGCCACTGGATTTCAAGCAACGCTTATGGCTCCAACTGA
TTTGCTTGCCAATCAGCATTATGAGTTTTTTGTTAAAGCTTTAAAAAATACTAATATAAGAGTCGGATTACTTACAGGTA
AGATACTGGGGACAGCTCGTAAAAATATTATGATACAACTTGACAACGATGAGATTGATATATTAGTCGGCACTCATGCT
TTATTTCAAGAAAAAGTAAGTTTTAAGAAATTAGGTTATATAGTTATTGATGAGCAGCATAGATTTGGGGTACAACAGCG
TTTGAATTTAATAAATAAAGGAGTAAATCCCGATGTGTTAGTTATGACTGCAACGCCGATTCCTCGCAGTCTTGCACTTA
CTATGTTTGGTGATATGACTATCTCAAAGTTAATGGGTAAGCCGAAAAGTCGTTTACCTATCGCTACAAATACCATGTCC
GTTAATAAGATAGAGCATATTATAGTAGCGATAAATAAGAAGCTTATTGCAGGTGAGCGGGTATATTGGATTTGTCCATT
GATAGAGCAGGGAGAGAAAGAAACGTCGGAAGAGGATAGTTTATTGATGGATGTGATGAATCGTTTTAACTCTATCGACA
ATATCTATCAAGGTTATACCGGTATTATTCACGGTAAGATGAAGAACGAGCAGAAAGACCAAATAATGAAGCAATTTAAG
GAAGGTGAAATTAAGATATTAGTTGCAACAACCGTTATTGAAGTCGGAATAGACATACCTGAAGCCACTTTGATAATTAT
TGAAAATGCTGAGCAATTTGGTCTCGCTCAACTTCATCAGCTTAGAGGTAGAGTAGGGCGGGGTAGTTTGCAGTCATATT
GTATATTGTTATACAATCCTAAAAGGCTTAGAAAAGTTGCACGAGGTAGGTTTGAGATAATGAAACAAACTAATGATGGA
TTTTATATAGCTGAGCAGGATTTAAAACTTCGAGGTAGCGGTGAGATTTTAGGAGTAAAACAAAGCGGCGAAATCGCATT
TTTCTTCGCCAATTTAGCGGACGATTATGACCTACTTCTTAAAGCGCATAAATTTGCAGCAATAGGCTCAAAAGGTAATG
TAAATTTTGTTAACTTTCAGATCAAGCTCTTTGCCAAATCTCAAGTAAGCGAGTTGGTTTAG

Upstream 100 bases:

>100_bases
CTTTTGCAAGAATGACATATTAATCATAATTTGTATATTTTATTATTCTTCTTTTATTATAAAGTATATATATTTGTATA
TAAGATAATTATGACTATAT

Downstream 100 bases:

>100_bases
TTTGAATATGCTATTTCCGCTTGACATTGGCGTTGTTGCGTGGATCGATTTTTCCGTCATTGTGAGAAGAATGACGCAGT
AATTCGATAAAGCAATCTCG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 713; Mature: 713

Protein sequence:

>713_residues
MLTILEKFLFSSVKTFINIREDTVSALKRLGIKNIRDLLFYLPVSYQNKILSPNLTEVRDGDIIQTEIVVESINLPKKSS
QPLKITASNDTGSLLLVFFHKPPPFIFNKLQVGTSHIISGKVQFFDHYLQIAHPEFIVNPKLAKEIEPIYSLTYLLSNKQ
LYSYIIKAIEIFEEKCKSIEDKEVKDYLDIILQNLQMLHVFHHCEEACMPTKQSSNVKLINSRLPQPLKGLHNDDLYTNA
KKQLAAKELIANQISLLNVRTQISRRQGNIYPKAVSIQANILNELGFELTSYQKQVIEEIECDQSDKIEMMRLLQGDVGS
GKTLVALLTMVNVVATGFQATLMAPTDLLANQHYEFFVKALKNTNIRVGLLTGKILGTARKNIMIQLDNDEIDILVGTHA
LFQEKVSFKKLGYIVIDEQHRFGVQQRLNLINKGVNPDVLVMTATPIPRSLALTMFGDMTISKLMGKPKSRLPIATNTMS
VNKIEHIIVAINKKLIAGERVYWICPLIEQGEKETSEEDSLLMDVMNRFNSIDNIYQGYTGIIHGKMKNEQKDQIMKQFK
EGEIKILVATTVIEVGIDIPEATLIIIENAEQFGLAQLHQLRGRVGRGSLQSYCILLYNPKRLRKVARGRFEIMKQTNDG
FYIAEQDLKLRGSGEILGVKQSGEIAFFFANLADDYDLLLKAHKFAAIGSKGNVNFVNFQIKLFAKSQVSELV

Sequences:

>Translated_713_residues
MLTILEKFLFSSVKTFINIREDTVSALKRLGIKNIRDLLFYLPVSYQNKILSPNLTEVRDGDIIQTEIVVESINLPKKSS
QPLKITASNDTGSLLLVFFHKPPPFIFNKLQVGTSHIISGKVQFFDHYLQIAHPEFIVNPKLAKEIEPIYSLTYLLSNKQ
LYSYIIKAIEIFEEKCKSIEDKEVKDYLDIILQNLQMLHVFHHCEEACMPTKQSSNVKLINSRLPQPLKGLHNDDLYTNA
KKQLAAKELIANQISLLNVRTQISRRQGNIYPKAVSIQANILNELGFELTSYQKQVIEEIECDQSDKIEMMRLLQGDVGS
GKTLVALLTMVNVVATGFQATLMAPTDLLANQHYEFFVKALKNTNIRVGLLTGKILGTARKNIMIQLDNDEIDILVGTHA
LFQEKVSFKKLGYIVIDEQHRFGVQQRLNLINKGVNPDVLVMTATPIPRSLALTMFGDMTISKLMGKPKSRLPIATNTMS
VNKIEHIIVAINKKLIAGERVYWICPLIEQGEKETSEEDSLLMDVMNRFNSIDNIYQGYTGIIHGKMKNEQKDQIMKQFK
EGEIKILVATTVIEVGIDIPEATLIIIENAEQFGLAQLHQLRGRVGRGSLQSYCILLYNPKRLRKVARGRFEIMKQTNDG
FYIAEQDLKLRGSGEILGVKQSGEIAFFFANLADDYDLLLKAHKFAAIGSKGNVNFVNFQIKLFAKSQVSELV
>Mature_713_residues
MLTILEKFLFSSVKTFINIREDTVSALKRLGIKNIRDLLFYLPVSYQNKILSPNLTEVRDGDIIQTEIVVESINLPKKSS
QPLKITASNDTGSLLLVFFHKPPPFIFNKLQVGTSHIISGKVQFFDHYLQIAHPEFIVNPKLAKEIEPIYSLTYLLSNKQ
LYSYIIKAIEIFEEKCKSIEDKEVKDYLDIILQNLQMLHVFHHCEEACMPTKQSSNVKLINSRLPQPLKGLHNDDLYTNA
KKQLAAKELIANQISLLNVRTQISRRQGNIYPKAVSIQANILNELGFELTSYQKQVIEEIECDQSDKIEMMRLLQGDVGS
GKTLVALLTMVNVVATGFQATLMAPTDLLANQHYEFFVKALKNTNIRVGLLTGKILGTARKNIMIQLDNDEIDILVGTHA
LFQEKVSFKKLGYIVIDEQHRFGVQQRLNLINKGVNPDVLVMTATPIPRSLALTMFGDMTISKLMGKPKSRLPIATNTMS
VNKIEHIIVAINKKLIAGERVYWICPLIEQGEKETSEEDSLLMDVMNRFNSIDNIYQGYTGIIHGKMKNEQKDQIMKQFK
EGEIKILVATTVIEVGIDIPEATLIIIENAEQFGLAQLHQLRGRVGRGSLQSYCILLYNPKRLRKVARGRFEIMKQTNDG
FYIAEQDLKLRGSGEILGVKQSGEIAFFFANLADDYDLLLKAHKFAAIGSKGNVNFVNFQIKLFAKSQVSELV

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=680, Percent_Identity=35.2941176470588, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1787357, Length=445, Percent_Identity=35.0561797752809, Blast_Score=252, Evalue=6e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 80647; Mature: 80647

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00435 PEROXIDASE_1 ; PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTILEKFLFSSVKTFINIREDTVSALKRLGIKNIRDLLFYLPVSYQNKILSPNLTEVRD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GDIIQTEIVVESINLPKKSSQPLKITASNDTGSLLLVFFHKPPPFIFNKLQVGTSHIISG
CCEEEEEEEEEECCCCCCCCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHCCCHHHHCC
KVQFFDHYLQIAHPEFIVNPKLAKEIEPIYSLTYLLSNKQLYSYIIKAIEIFEEKCKSIE
HHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
DKEVKDYLDIILQNLQMLHVFHHCEEACMPTKQSSNVKLINSRLPQPLKGLHNDDLYTNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHCCCHHHHCCCCCCCHHHH
KKQLAAKELIANQISLLNVRTQISRRQGNIYPKAVSIQANILNELGFELTSYQKQVIEEI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHH
ECDQSDKIEMMRLLQGDVGSGKTLVALLTMVNVVATGFQATLMAPTDLLANQHYEFFVKA
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCHHHHHHHH
LKNTNIRVGLLTGKILGTARKNIMIQLDNDEIDILVGTHALFQEKVSFKKLGYIVIDEQH
HCCCCEEEEEEECHHHHCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHCCEEEEECHH
RFGVQQRLNLINKGVNPDVLVMTATPIPRSLALTMFGDMTISKLMGKPKSRLPIATNTMS
HCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCC
VNKIEHIIVAINKKLIAGERVYWICPLIEQGEKETSEEDSLLMDVMNRFNSIDNIYQGYT
HHHHHHEEEEECCCEECCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
GIIHGKMKNEQKDQIMKQFKEGEIKILVATTVIEVGIDIPEATLIIIENAEQFGLAQLHQ
EEEECCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEEEEEECCCHHHHHHHHH
LRGRVGRGSLQSYCILLYNPKRLRKVARGRFEIMKQTNDGFYIAEQDLKLRGSGEILGVK
HHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCEEEEE
QSGEIAFFFANLADDYDLLLKAHKFAAIGSKGNVNFVNFQIKLFAKSQVSELV
CCCCEEEEEECCCCCHHHHHHHHHHHEECCCCCEEEEEEEEEEEEHHHHHHCC
>Mature Secondary Structure
MLTILEKFLFSSVKTFINIREDTVSALKRLGIKNIRDLLFYLPVSYQNKILSPNLTEVRD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GDIIQTEIVVESINLPKKSSQPLKITASNDTGSLLLVFFHKPPPFIFNKLQVGTSHIISG
CCEEEEEEEEEECCCCCCCCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHCCCHHHHCC
KVQFFDHYLQIAHPEFIVNPKLAKEIEPIYSLTYLLSNKQLYSYIIKAIEIFEEKCKSIE
HHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
DKEVKDYLDIILQNLQMLHVFHHCEEACMPTKQSSNVKLINSRLPQPLKGLHNDDLYTNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHCCCHHHHCCCCCCCHHHH
KKQLAAKELIANQISLLNVRTQISRRQGNIYPKAVSIQANILNELGFELTSYQKQVIEEI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHH
ECDQSDKIEMMRLLQGDVGSGKTLVALLTMVNVVATGFQATLMAPTDLLANQHYEFFVKA
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCHHHHHHHH
LKNTNIRVGLLTGKILGTARKNIMIQLDNDEIDILVGTHALFQEKVSFKKLGYIVIDEQH
HCCCCEEEEEEECHHHHCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHCCEEEEECHH
RFGVQQRLNLINKGVNPDVLVMTATPIPRSLALTMFGDMTISKLMGKPKSRLPIATNTMS
HCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCC
VNKIEHIIVAINKKLIAGERVYWICPLIEQGEKETSEEDSLLMDVMNRFNSIDNIYQGYT
HHHHHHEEEEECCCEECCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
GIIHGKMKNEQKDQIMKQFKEGEIKILVATTVIEVGIDIPEATLIIIENAEQFGLAQLHQ
EEEECCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEEEEEECCCHHHHHHHHH
LRGRVGRGSLQSYCILLYNPKRLRKVARGRFEIMKQTNDGFYIAEQDLKLRGSGEILGVK
HHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCEEEEE
QSGEIAFFFANLADDYDLLLKAHKFAAIGSKGNVNFVNFQIKLFAKSQVSELV
CCCCEEEEEECCCCCHHHHHHHHHHHEECCCCCEEEEEEEEEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]