Click here to switch to the map view.

The map label for this gene is fadB [C]

Identifier: 15892765

GI number: 15892765

Start: 793470

End: 793934

Strand: Reverse

Name: fadB [C]

Synonym: RC0842

Alternate gene names: 15892765

Gene position: 793934-793470 (Counterclockwise)

Preceding gene: 15892766

Following gene: 15892764

Centisome position: 62.58

GC content: 30.32

Gene sequence:

>465_bases
ATGCAAAATAAAATAAAAAAAGTTTGTGTTATTGGTGCGGGAGTAATCGGTTCAGGGATTGCAGCGTTAATTGCTAATTC
CTCTTATAAAGTAGTGCTGCTTGATATTATCGCTAAAGATTCCGATGATCCTAATAAAATAGTTAACACCGCTAAAGAAA
ATTTGCATAAACAAAAACCTCCACCTCCACCTTTATCTTTTCCTGATAAAGCAAATTTCATTACCATCGGTAATTTAGAA
TATGATTTAGATTTAATTAAAGAATGTGATTTAGTGATTGAAGTTATTGTTGAGAAGTTAGAAATCAAACACCAATTATA
TAATAAAATTATTCCTTATCTTAAAGAAGATGCAATTATTGCTTCTAATACCTCTACATTACCGCTTGAAAGACTCAAAG
AGAATTTACCAGATAATATTAAATCTAGGTTCGTTATTACGCATTTCTTCAATCCGCCAAGATAA

Upstream 100 bases:

>100_bases
ATCCCTTGGCTTGACCACGGGATCCAAAAAATAATAAAAATTTTTAGTATTTTTAACTGGACCCCATGGTCAAGGCACGG
GGTAACACAGAAGGTAACTT

Downstream 100 bases:

>100_bases
TATGGAACTGCTTGAGTTAATTATAGACCCTATGATAAAGGCTGAAGTAATAGAAAGAGTATCAGAGTTCTTAACGAAAA
CGCTTGGTAAAATTATAGTA

Product: putative 3-hydroxyacyl-CoA dehydrogenase (FadB)

Products: NA

Alternate protein names: 3-hydroxyacyl-CoA dehydrogenase; Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MQNKIKKVCVIGAGVIGSGIAALIANSSYKVVLLDIIAKDSDDPNKIVNTAKENLHKQKPPPPPLSFPDKANFITIGNLE
YDLDLIKECDLVIEVIVEKLEIKHQLYNKIIPYLKEDAIIASNTSTLPLERLKENLPDNIKSRFVITHFFNPPR

Sequences:

>Translated_154_residues
MQNKIKKVCVIGAGVIGSGIAALIANSSYKVVLLDIIAKDSDDPNKIVNTAKENLHKQKPPPPPLSFPDKANFITIGNLE
YDLDLIKECDLVIEVIVEKLEIKHQLYNKIIPYLKEDAIIASNTSTLPLERLKENLPDNIKSRFVITHFFNPPR
>Mature_154_residues
MQNKIKKVCVIGAGVIGSGIAALIANSSYKVVLLDIIAKDSDDPNKIVNTAKENLHKQKPPPPPLSFPDKANFITIGNLE
YDLDLIKECDLVIEVIVEKLEIKHQLYNKIIPYLKEDAIIASNTSTLPLERLKENLPDNIKSRFVITHFFNPPR

Specific function: FADb And FADa Are The Alpha And Beta Subunits Of The Multifunctional Enzyme Complex Of The Fatty Acid Degradation Cycle. [C]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI296179427, Length=155, Percent_Identity=32.9032258064516, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI296179429, Length=155, Percent_Identity=32.9032258064516, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17553560, Length=162, Percent_Identity=32.7160493827161, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17549919, Length=152, Percent_Identity=34.2105263157895, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35; =4.2.1.17; =5.3.3.8 [H]

Molecular weight: Translated: 17227; Mature: 17227

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNKIKKVCVIGAGVIGSGIAALIANSSYKVVLLDIIAKDSDDPNKIVNTAKENLHKQKP
CCCHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCC
PPPPLSFPDKANFITIGNLEYDLDLIKECDLVIEVIVEKLEIKHQLYNKIIPYLKEDAII
CCCCCCCCCCCCEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ASNTSTLPLERLKENLPDNIKSRFVITHFFNPPR
ECCCCCCCHHHHHHCCCCCHHHCEEEEECCCCCC
>Mature Secondary Structure
MQNKIKKVCVIGAGVIGSGIAALIANSSYKVVLLDIIAKDSDDPNKIVNTAKENLHKQKP
CCCHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCC
PPPPLSFPDKANFITIGNLEYDLDLIKECDLVIEVIVEKLEIKHQLYNKIIPYLKEDAII
CCCCCCCCCCCCEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ASNTSTLPLERLKENLPDNIKSRFVITHFFNPPR
ECCCCCCCHHHHHHCCCCCHHHCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA