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The map label for this gene is bipA [H]

Identifier: 15892272

GI number: 15892272

Start: 351482

End: 353311

Strand: Reverse

Name: bipA [H]

Synonym: RC0349

Alternate gene names: 15892272

Gene position: 353311-351482 (Counterclockwise)

Preceding gene: 15892287

Following gene: 15892264

Centisome position: 27.85

GC content: 41.86

Gene sequence:

>1830_bases
ATGACATCTATTCGTAATATAGCAATTATTGCCCACGTTGATCATGGAAAAACTACGCTTGTTGATAACATGCTTAAACA
AAGCGGAACATTTAGAGCTAACCAAGCAGTTGCTGAGCGTGCTATGGACTCTAACGATCTTGAGCGTGAGCGTGGAATCA
CGATACTTGCCAAATGCACTGCTCTTATGTGGAACGATATCCGTATCAATATAGTTGATACGCCAGGACACGCCGATTTT
GGCGGTGAAGTAGAACGCATCCTTAGCATGGTTGACGGTGTAGTGCTACTTGTCGATGCATCGGAAGGACCAATGCCGCA
AACAAAATTCGTGCTTTCTAAAGCGTTAAATCTCGGCTTAAAACCTATTGTCGTTATTAATAAAATCGATAGAGATGACC
AAAGAATTAAAGAAGTTATCGATGAAGTATTTGAGCTATTTGTGGCACTTGAAGCAAACAACGATCAGCTTGACTTCCCT
ATAGTTTATGCATCAGGTAGAGCAGGTAGAGCATCTTTAACCTTTGATGATAAAATTAATCCTTTAGACAATTTAGCAGA
TGATTTAGCACCGCTTTTCGACCTTATAGTACAGCATGTACCAAAACCCTTAGCCGATGACAAAGCACCGTTTTCTATGC
TTGTTACTACTAGAGAATATAACTCTTTCTTCGGTAGGGTTTTAACAGGTCGTGTACAAAGCGGCACTGTCAAAATTAAC
CAAAACGTAAAAGTATTAAATCGTGAGAATAAAGTACTTGAAACCGGACGTATCACTAAAATATTAGCCTTTAGAGGCTT
AGAGCGAATCGCTATAAATGATGCTACAGCCGGCGATATTATTGCCGTAGCAGGCGTTGAAAACGCCAACGTTGCCGATA
CTATCTGCTCCCCTGAGGTAACCGAGGCCGTACCGTCTCTACCTATCGATCCGCCGACTTTATCCATGACTTTTAGCGTT
AATGACTCACCGCTTGCAGGAAGCGAAGGGACAAAAGTTACGTCGAGCTTAATTGGAGCTAGGTTAATGCGTGAGCTTGA
AAGTAACGTTGCCTTAAAAGTTACTGAAGCTGCCGAGAAAAATGCTTTCCAAGTTGCAGGGCGTGGTGAGTTACAACTTG
GTATCTTAATTGAAACTATGCGTCGTGAAGGATTTGAGCTATCTATTAGCAGACCCGAAGTATTATTCCAAACTGATGAG
AAAGGTAATAAGCAAGAACCGATGGAAGAAATCCAAGTTGACGTTGATGATGATTATGTTGGAGTAGTCGTAAAATCTTT
AGCACTGAGAAAAGCCGAAATGACTGATATGAGGCCGTCAGGCGGCGGTAAAAGCCGTGTTACGTTTATCGGACCGTCTA
GAGGGTTAATCGGCTATCACAGCCAGTTTTTAACCGAAACACGAGGCACAGGAATTATGAATCGTATTTTCCATGGATAT
GCTGATTATAAAGGAAATATCGAGGGAAGACGTAACGGTGTGCTTATCTCTAACGGTGACGGGGCAGCAGTCGCATATGC
TCTATGGAATCTAGAAGAAAGGGGAAAAATGTTTATAAACCCTAGTGACAAAGTATATAGAGGCATGATTATCGGCGAAC
ATAATCGTGATAATGATTTAGAGGTAAACCCACTAAAAGCGAAACAACTGAGCAACGTTAGAGCAACAGGTAAAGACGAA
GCCATAAGGCTAACTCCGCCAATGCTTTTAACGTTAGAGCAGGCAATCAGCTATATACAAGATGACGAGCGAGTTGAAGT
CACACCGAAATCTATTCGTTTACGTAAAGCTCTACTTGACCCTAACGACCGTAAAAGAGCTGCAAAGTAG

Upstream 100 bases:

>100_bases
ACAGTTAAATCAATTTCTTTTTCAAGAACTTATATTCCAATTTTTGGTATTTTAGTGTATAATACGAAAAACTATTGTAA
ACTTGTGAGAATTTTTAAAG

Downstream 100 bases:

>100_bases
ATATGCCTAAAAAAGTTGACATCGTCATTGCGAGGAAAAACTGTAAGTTTTGACAAAGCAATCTCTGGAATCTTGCTTTA
TGAGATTGCCACGCTCCTTT

Product: GTP-binding protein

Products: NA

Alternate protein names: Tyrosine phosphorylated protein A [H]

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MTSIRNIAIIAHVDHGKTTLVDNMLKQSGTFRANQAVAERAMDSNDLERERGITILAKCTALMWNDIRINIVDTPGHADF
GGEVERILSMVDGVVLLVDASEGPMPQTKFVLSKALNLGLKPIVVINKIDRDDQRIKEVIDEVFELFVALEANNDQLDFP
IVYASGRAGRASLTFDDKINPLDNLADDLAPLFDLIVQHVPKPLADDKAPFSMLVTTREYNSFFGRVLTGRVQSGTVKIN
QNVKVLNRENKVLETGRITKILAFRGLERIAINDATAGDIIAVAGVENANVADTICSPEVTEAVPSLPIDPPTLSMTFSV
NDSPLAGSEGTKVTSSLIGARLMRELESNVALKVTEAAEKNAFQVAGRGELQLGILIETMRREGFELSISRPEVLFQTDE
KGNKQEPMEEIQVDVDDDYVGVVVKSLALRKAEMTDMRPSGGGKSRVTFIGPSRGLIGYHSQFLTETRGTGIMNRIFHGY
ADYKGNIEGRRNGVLISNGDGAAVAYALWNLEERGKMFINPSDKVYRGMIIGEHNRDNDLEVNPLKAKQLSNVRATGKDE
AIRLTPPMLLTLEQAISYIQDDERVEVTPKSIRLRKALLDPNDRKRAAK

Sequences:

>Translated_609_residues
MTSIRNIAIIAHVDHGKTTLVDNMLKQSGTFRANQAVAERAMDSNDLERERGITILAKCTALMWNDIRINIVDTPGHADF
GGEVERILSMVDGVVLLVDASEGPMPQTKFVLSKALNLGLKPIVVINKIDRDDQRIKEVIDEVFELFVALEANNDQLDFP
IVYASGRAGRASLTFDDKINPLDNLADDLAPLFDLIVQHVPKPLADDKAPFSMLVTTREYNSFFGRVLTGRVQSGTVKIN
QNVKVLNRENKVLETGRITKILAFRGLERIAINDATAGDIIAVAGVENANVADTICSPEVTEAVPSLPIDPPTLSMTFSV
NDSPLAGSEGTKVTSSLIGARLMRELESNVALKVTEAAEKNAFQVAGRGELQLGILIETMRREGFELSISRPEVLFQTDE
KGNKQEPMEEIQVDVDDDYVGVVVKSLALRKAEMTDMRPSGGGKSRVTFIGPSRGLIGYHSQFLTETRGTGIMNRIFHGY
ADYKGNIEGRRNGVLISNGDGAAVAYALWNLEERGKMFINPSDKVYRGMIIGEHNRDNDLEVNPLKAKQLSNVRATGKDE
AIRLTPPMLLTLEQAISYIQDDERVEVTPKSIRLRKALLDPNDRKRAAK
>Mature_608_residues
TSIRNIAIIAHVDHGKTTLVDNMLKQSGTFRANQAVAERAMDSNDLERERGITILAKCTALMWNDIRINIVDTPGHADFG
GEVERILSMVDGVVLLVDASEGPMPQTKFVLSKALNLGLKPIVVINKIDRDDQRIKEVIDEVFELFVALEANNDQLDFPI
VYASGRAGRASLTFDDKINPLDNLADDLAPLFDLIVQHVPKPLADDKAPFSMLVTTREYNSFFGRVLTGRVQSGTVKINQ
NVKVLNRENKVLETGRITKILAFRGLERIAINDATAGDIIAVAGVENANVADTICSPEVTEAVPSLPIDPPTLSMTFSVN
DSPLAGSEGTKVTSSLIGARLMRELESNVALKVTEAAEKNAFQVAGRGELQLGILIETMRREGFELSISRPEVLFQTDEK
GNKQEPMEEIQVDVDDDYVGVVVKSLALRKAEMTDMRPSGGGKSRVTFIGPSRGLIGYHSQFLTETRGTGIMNRIFHGYA
DYKGNIEGRRNGVLISNGDGAAVAYALWNLEERGKMFINPSDKVYRGMIIGEHNRDNDLEVNPLKAKQLSNVRATGKDEA
IRLTPPMLLTLEQAISYIQDDERVEVTPKSIRLRKALLDPNDRKRAAK

Specific function: Probably interacts with the ribosomes in a GTP dependent manner. GTPase that mediates interactions between enteropathogenic E.coli (EPEC) and epithelial cells [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=344, Percent_Identity=29.6511627906977, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=43.609022556391, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI18390331, Length=133, Percent_Identity=45.1127819548872, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI25306287, Length=181, Percent_Identity=35.9116022099448, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI19923640, Length=181, Percent_Identity=35.9116022099448, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI25306283, Length=181, Percent_Identity=35.9116022099448, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI4503483, Length=145, Percent_Identity=37.2413793103448, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310132016, Length=110, Percent_Identity=40, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI310110807, Length=110, Percent_Identity=40, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI310123363, Length=110, Percent_Identity=40, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI34147630, Length=281, Percent_Identity=29.1814946619217, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI217272894, Length=136, Percent_Identity=37.5, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI217272892, Length=136, Percent_Identity=37.5, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI94966752, Length=129, Percent_Identity=31.7829457364341, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI48994988, Length=607, Percent_Identity=54.3657331136738, Blast_Score=660, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=512, Percent_Identity=24.609375, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI1789738, Length=148, Percent_Identity=37.8378378378378, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790835, Length=146, Percent_Identity=33.5616438356164, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789737, Length=282, Percent_Identity=28.7234042553192, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790412, Length=282, Percent_Identity=28.7234042553192, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17557151, Length=247, Percent_Identity=33.6032388663968, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17556745, Length=144, Percent_Identity=39.5833333333333, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71988819, Length=142, Percent_Identity=38.0281690140845, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71988811, Length=142, Percent_Identity=38.0281690140845, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17506493, Length=173, Percent_Identity=32.3699421965318, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17533571, Length=134, Percent_Identity=41.7910447761194, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17552882, Length=135, Percent_Identity=37.7777777777778, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17556456, Length=140, Percent_Identity=33.5714285714286, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25141371, Length=244, Percent_Identity=28.6885245901639, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323320, Length=474, Percent_Identity=26.7932489451477, Blast_Score=134, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6324707, Length=163, Percent_Identity=37.4233128834356, Blast_Score=114, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6320593, Length=163, Percent_Identity=37.4233128834356, Blast_Score=114, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6324761, Length=277, Percent_Identity=31.4079422382672, Blast_Score=100, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6323098, Length=166, Percent_Identity=37.9518072289157, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324166, Length=182, Percent_Identity=36.2637362637363, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322359, Length=152, Percent_Identity=36.1842105263158, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324550, Length=240, Percent_Identity=25.4166666666667, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI78706572, Length=410, Percent_Identity=27.3170731707317, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24582462, Length=133, Percent_Identity=44.3609022556391, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI28574573, Length=161, Percent_Identity=37.888198757764, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24585709, Length=167, Percent_Identity=34.7305389221557, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI221458488, Length=162, Percent_Identity=40.7407407407407, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24585711, Length=167, Percent_Identity=34.7305389221557, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24585713, Length=167, Percent_Identity=34.7305389221557, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281363316, Length=308, Percent_Identity=28.2467532467532, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17864358, Length=308, Percent_Identity=28.2467532467532, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357743, Length=171, Percent_Identity=36.2573099415205, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19921738, Length=262, Percent_Identity=28.6259541984733, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28572034, Length=148, Percent_Identity=33.1081081081081, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 67018; Mature: 66886

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIRNIAIIAHVDHGKTTLVDNMLKQSGTFRANQAVAERAMDSNDLERERGITILAKCT
CCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHCCCEEEEEHH
ALMWNDIRINIVDTPGHADFGGEVERILSMVDGVVLLVDASEGPMPQTKFVLSKALNLGL
HHEECCEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCC
KPIVVINKIDRDDQRIKEVIDEVFELFVALEANNDQLDFPIVYASGRAGRASLTFDDKIN
CEEEEEECCCCCHHHHHHHHHHHHHHEEEEECCCCCEEEEEEEECCCCCCEEEEECCCCC
PLDNLADDLAPLFDLIVQHVPKPLADDKAPFSMLVTTREYNSFFGRVLTGRVQSGTVKIN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHCCCCCCCEEEEC
QNVKVLNRENKVLETGRITKILAFRGLERIAINDATAGDIIAVAGVENANVADTICSPEV
CCEEEEECCCCEECCCCHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCHHHCCCCHH
TEAVPSLPIDPPTLSMTFSVNDSPLAGSEGTKVTSSLIGARLMRELESNVALKVTEAAEK
HHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCC
NAFQVAGRGELQLGILIETMRREGFELSISRPEVLFQTDEKGNKQEPMEEIQVDVDDDYV
CCEEECCCCCEEEHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCHHHHEECCCCCHH
GVVVKSLALRKAEMTDMRPSGGGKSRVTFIGPSRGLIGYHSQFLTETRGTGIMNRIFHGY
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
ADYKGNIEGRRNGVLISNGDGAAVAYALWNLEERGKMFINPSDKVYRGMIIGEHNRDNDL
CCCCCCCCCCCCCEEEECCCCCEEEEEECCHHHCCCEEECCCCCEEEEEEEECCCCCCCC
EVNPLKAKQLSNVRATGKDEAIRLTPPMLLTLEQAISYIQDDERVEVTPKSIRLRKALLD
EECCCCHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHCC
PNDRKRAAK
CCCHHCCCC
>Mature Secondary Structure 
TSIRNIAIIAHVDHGKTTLVDNMLKQSGTFRANQAVAERAMDSNDLERERGITILAKCT
CCCCEEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHCCCEEEEEHH
ALMWNDIRINIVDTPGHADFGGEVERILSMVDGVVLLVDASEGPMPQTKFVLSKALNLGL
HHEECCEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCC
KPIVVINKIDRDDQRIKEVIDEVFELFVALEANNDQLDFPIVYASGRAGRASLTFDDKIN
CEEEEEECCCCCHHHHHHHHHHHHHHEEEEECCCCCEEEEEEEECCCCCCEEEEECCCCC
PLDNLADDLAPLFDLIVQHVPKPLADDKAPFSMLVTTREYNSFFGRVLTGRVQSGTVKIN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHCCCCCCCEEEEC
QNVKVLNRENKVLETGRITKILAFRGLERIAINDATAGDIIAVAGVENANVADTICSPEV
CCEEEEECCCCEECCCCHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCHHHCCCCHH
TEAVPSLPIDPPTLSMTFSVNDSPLAGSEGTKVTSSLIGARLMRELESNVALKVTEAAEK
HHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCC
NAFQVAGRGELQLGILIETMRREGFELSISRPEVLFQTDEKGNKQEPMEEIQVDVDDDYV
CCEEECCCCCEEEHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCHHHHEECCCCCHH
GVVVKSLALRKAEMTDMRPSGGGKSRVTFIGPSRGLIGYHSQFLTETRGTGIMNRIFHGY
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
ADYKGNIEGRRNGVLISNGDGAAVAYALWNLEERGKMFINPSDKVYRGMIIGEHNRDNDL
CCCCCCCCCCCCCEEEECCCCCEEEEEECCHHHCCCEEECCCCCEEEEEEEECCCCCCCC
EVNPLKAKQLSNVRATGKDEAIRLTPPMLLTLEQAISYIQDDERVEVTPKSIRLRKALLD
EECCCCHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHCC
PNDRKRAAK
CCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9622352 [H]