BacMap

Definition	Staphylococcus aureus subsp. aureus COL chromosome, complete genome.
Accession	NC_002951
Length	2,809,422

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The map label for this gene is gudP [H]

Identifier: 57651019

GI number: 57651019

Start: 2581558

End: 2582835

Strand: Reverse

Name: gudP [H]

Synonym: SACOL2521

Alternate gene names: 57651019

Gene position: 2582835-2581558 (Counterclockwise)

Preceding gene: 57651021

Following gene: 57651018

Centisome position: 91.93

GC content: 36.15

Gene sequence:

>1278_bases
ATGAAGGAAAAACGAACTAACGTAAGGTGGATGTTCGCGCTTGCGTTCTTCTTTATTGGGGTTATTGCGTATATGGATAG
AGCAAACATTTCATATATCGCTAAGCAAATGATGGATGATTTAGGGATGACAAAACCACAATTTGGTTTATTGGCATCAT
TCTTCTCTCTAGGTTATGCATTAATGCAAGTACCATCGGGGATGTTGGCTGAAAAATTCGGTCCACGTAAGATGATTACA
ATTGCATTAGTTTGGTGGAGTGCATTTACAATCTTAACGGGTATGATTAAGAACCACGGTTTAATTTATTTAGTGAGATT
CTTATTTGGTGTAGGTGAGGCGCCAATGTACCCTTCTAATGCTGTGTTTAATTCATTTTGGTTCTCTAAAAATGAAAAAG
GTAGAGCATCAAGTGCATTATTAGCAGGATCATATTTCGGACCTGTATTAGCACCAATAGTTACAATTGCTATTGTTAAC
GCATTTAACTGGCAAGCAGTATTTTACATTTTTGGTGCAGTAGGTATTTTAATGGCTGTATTATGGGCGATTATTGCCAA
AGACTTACCTGAGCAACATAGAATGGTTAATGAAGCGGAGAAACGTTTCATTATGGAAAATCGTGATATCGTAGCTACTG
AAAAGTCATCACCACCATGGAATGATTTCTTTAAACGTTTTAGCTTCTATGCAATTGCAATTCAATACTTTGTTGTACAA
TTTATCATTACATTATTCTTAATTTGGTTACCGACGTATTTAACAGAAGTATTCCACGTTAACTTTAAAGAAATGAGCAT
TAGTTCATTACCTTGGTTATTAATGTTCTTCTTAATCTTATCAGCAGGTGCAATTTCTGACCGTGTATTAGGATTAGGTC
GTTCAAAATTCGTAGCTAGAGGTGTAATTGCAATTGCAGGATTTATTGTGTTTGCAGTTTCAATTATCTTTGCTGTACGC
ACAGGAAATTTATATGTAAGTATTTTCTGGTTATCACTAGGTCTTGGTGGTATCGGTATTTCAATGGGTATGAGTTGGGC
TGCAGCAACTGACTTAGGACGTAACTTCTCTGGTACAGTATCAGGGTGGATGAACTTATGGGGTAATATAGGTGCATTAA
TCAGTCCGCTATTAGCAGGTCTATTCGTAGAACATTTGGGTTGGACAATGACATTCCAATTGTTAATCGTTCCAGCAGTA
ATCGCTGTGATTATGTGGTTCTATGTGAAACCAGATCAACCTTTAATTGTTAGTGATGATAAAGCAATAGAAAAATAA

Upstream 100 bases:

>100_bases
ACAATTTTGTGACAAAGTAGGGGTGGACATGCCAGATGTCCGAAAATTTTAACGTTTCAGGGTAAGTTTTAAAAAATTAA
TTAGGGAAGTAGGAATAGTT

Downstream 100 bases:

>100_bases
TTTAAACAAGCAGTAAGCTTTCACATAGTTGGGGCTTATTGCTTTTTTTGCGTTGAAATTGAAACTTTTTAAAACAGATA
TGGTTTAAGATGAAAATGAA

Product: transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMTKPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMIT
IALVWWSAFTILTGMIKNHGLIYLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVN
AFNWQAVFYIFGAVGILMAVLWAIIAKDLPEQHRMVNEAEKRFIMENRDIVATEKSSPPWNDFFKRFSFYAIAIQYFVVQ
FIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMFFLILSAGAISDRVLGLGRSKFVARGVIAIAGFIVFAVSIIFAVR
TGNLYVSIFWLSLGLGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLAGLFVEHLGWTMTFQLLIVPAV
IAVIMWFYVKPDQPLIVSDDKAIEK

Sequences:

>Translated_425_residues
MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMTKPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMIT
IALVWWSAFTILTGMIKNHGLIYLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVN
AFNWQAVFYIFGAVGILMAVLWAIIAKDLPEQHRMVNEAEKRFIMENRDIVATEKSSPPWNDFFKRFSFYAIAIQYFVVQ
FIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMFFLILSAGAISDRVLGLGRSKFVARGVIAIAGFIVFAVSIIFAVR
TGNLYVSIFWLSLGLGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLAGLFVEHLGWTMTFQLLIVPAV
IAVIMWFYVKPDQPLIVSDDKAIEK
>Mature_425_residues
MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMTKPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMIT
IALVWWSAFTILTGMIKNHGLIYLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVN
AFNWQAVFYIFGAVGILMAVLWAIIAKDLPEQHRMVNEAEKRFIMENRDIVATEKSSPPWNDFFKRFSFYAIAIQYFVVQ
FIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMFFLILSAGAISDRVLGLGRSKFVARGVIAIAGFIVFAVSIIFAVR
TGNLYVSIFWLSLGLGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLAGLFVEHLGWTMTFQLLIVPAV
IAVIMWFYVKPDQPLIVSDDKAIEK

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=338, Percent_Identity=28.1065088757396, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI9945322, Length=350, Percent_Identity=26.2857142857143, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI21322234, Length=349, Percent_Identity=26.3610315186246, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI9966811, Length=395, Percent_Identity=24.5569620253165, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI148743791, Length=354, Percent_Identity=24.0112994350282, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI154800443, Length=392, Percent_Identity=26.2755102040816, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI154350196, Length=385, Percent_Identity=23.8961038961039, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI5031955, Length=249, Percent_Identity=28.1124497991968, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4885441, Length=363, Percent_Identity=23.9669421487603, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI148728191, Length=277, Percent_Identity=24.187725631769, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI223718438, Length=158, Percent_Identity=29.746835443038, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1789515, Length=431, Percent_Identity=26.9141531322506, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI1789152, Length=444, Percent_Identity=27.9279279279279, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI2367379, Length=399, Percent_Identity=25.31328320802, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87082320, Length=398, Percent_Identity=25.3768844221106, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI2367193, Length=425, Percent_Identity=24, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082071, Length=433, Percent_Identity=22.8637413394919, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788573, Length=417, Percent_Identity=22.3021582733813, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17554148, Length=329, Percent_Identity=26.4437689969605, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI115533556, Length=351, Percent_Identity=28.2051282051282, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI115533554, Length=351, Percent_Identity=28.2051282051282, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17535049, Length=430, Percent_Identity=23.4883720930233, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17554962, Length=329, Percent_Identity=26.1398176291793, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71997452, Length=397, Percent_Identity=22.9219143576826, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193205400, Length=338, Percent_Identity=23.6686390532544, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32565914, Length=344, Percent_Identity=22.9651162790698, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17552542, Length=420, Percent_Identity=21.6666666666667, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI32565916, Length=239, Percent_Identity=25.1046025104602, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25141318, Length=372, Percent_Identity=22.5806451612903, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI25141316, Length=372, Percent_Identity=22.5806451612903, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25141341, Length=366, Percent_Identity=21.8579234972678, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86561091, Length=276, Percent_Identity=24.2753623188406, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71991448, Length=385, Percent_Identity=21.8181818181818, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71991453, Length=385, Percent_Identity=21.8181818181818, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17563054, Length=352, Percent_Identity=23.2954545454545, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17532009, Length=241, Percent_Identity=23.2365145228216, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561498, Length=209, Percent_Identity=29.6650717703349, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560030, Length=224, Percent_Identity=22.7678571428571, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17536545, Length=417, Percent_Identity=25.1798561151079, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71983953, Length=321, Percent_Identity=22.4299065420561, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI115534558, Length=206, Percent_Identity=28.6407766990291, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562692, Length=322, Percent_Identity=22.360248447205, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17537329, Length=324, Percent_Identity=24.6913580246914, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32566049, Length=409, Percent_Identity=21.0268948655257, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560966, Length=226, Percent_Identity=23.8938053097345, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17566884, Length=290, Percent_Identity=21.3793103448276, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115533871, Length=306, Percent_Identity=22.2222222222222, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17557430, Length=271, Percent_Identity=24.3542435424354, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534566, Length=271, Percent_Identity=24.3542435424354, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19922400, Length=363, Percent_Identity=29.2011019283747, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24654215, Length=363, Percent_Identity=29.2011019283747, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583789, Length=362, Percent_Identity=25.414364640884, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28573708, Length=426, Percent_Identity=24.6478873239437, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28573707, Length=426, Percent_Identity=24.6478873239437, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI19920686, Length=386, Percent_Identity=26.9430051813472, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24584153, Length=381, Percent_Identity=24.1469816272966, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI20130135, Length=415, Percent_Identity=26.7469879518072, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24655271, Length=409, Percent_Identity=26.8948655256724, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24639764, Length=385, Percent_Identity=26.7532467532467, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI20130167, Length=416, Percent_Identity=24.0384615384615, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24648416, Length=418, Percent_Identity=25.8373205741627, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21356189, Length=418, Percent_Identity=25.8373205741627, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24580790, Length=365, Percent_Identity=24.3835616438356, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45550460, Length=418, Percent_Identity=25.1196172248804, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641682, Length=373, Percent_Identity=25.7372654155496, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24655255, Length=384, Percent_Identity=24.4791666666667, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573299, Length=390, Percent_Identity=25.6410256410256, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI62484226, Length=355, Percent_Identity=24.2253521126761, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24658689, Length=411, Percent_Identity=22.6277372262774, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI45552797, Length=411, Percent_Identity=22.6277372262774, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI20129235, Length=342, Percent_Identity=24.8538011695906, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI45550364, Length=423, Percent_Identity=23.6406619385343, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24658658, Length=431, Percent_Identity=22.5058004640371, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24651789, Length=368, Percent_Identity=24.7282608695652, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651787, Length=368, Percent_Identity=24.7282608695652, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24653727, Length=377, Percent_Identity=24.9336870026525, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24658666, Length=443, Percent_Identity=22.7990970654628, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221474708, Length=156, Percent_Identity=25.6410256410256, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24658696, Length=356, Percent_Identity=22.1910112359551, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281361682, Length=409, Percent_Identity=20.0488997555012, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47627; Mature: 47627

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCC
>Mature Secondary Structure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HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]