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The map label for this gene is yvmA [H]

Identifier: 57651021

GI number: 57651021

Start: 2584090

End: 2585253

Strand: Reverse

Name: yvmA [H]

Synonym: SACOL2523

Alternate gene names: 57651021

Gene position: 2585253-2584090 (Counterclockwise)

Preceding gene: 57651022

Following gene: 57651019

Centisome position: 92.02

GC content: 28.78

Gene sequence:

>1164_bases
ATGATTAATAGTAATATCAGATTATATATTCTAGGATTTTTAGCATTTTTCGCATCATTGATTCAAAACATATACACGCC
TATTATTCCGAGACTATATGACGATTTTCAAGTACCACTATTTTGGATAAATGCGACAGTTGGCGGTTTTATATTTATCG
TTGCAGTTATGCAAATTGTACTTGGTAGAAGTATAGATTCTCGTGATTCGAAAAAAGTACTTTTAACGGGATTGGGAATA
GTAATCATATCTAGCTTTATTTGTGCAGTGACACATAACTTTATATTATTTGCTATATCAAGGTTATTTCAAGCAATTGG
TTGCGGAATTATTCCTCTCGTGACTTTAACTTTATTAGCCAAACTAAGTACAGATAATGGTAGAGCTCAAGCTATGGCGA
ACTATCAAATATTTTTATCATGTGCACCAGCTTTGGCACCAATCTTAGGGAGTACTTTAGGTGCAAGATGGGATTATATT
GGTATTTTTAGTTTTTTGCTCGTTATATCTATCGTATTATTTTTGATTATCTTTTTTATTGATATTCCAAATGTTGAAAA
AGGGATTGTAAAATTAACTGAAAAAATTGAAGAAAAATATTTGACCGATAAAGTGTTTATTACTTTAGTGACATTGGGAT
TTTTAATATTTTTTACGTACTTTTCAATATTAGTTTATTTACCAACATTATTAAATAATACCTATGATATAGGCGTTGGA
ATATCAGGAGTTTTGTTTTTACCTATTACTGTTAGTGTTATATTAGGAAGTTTATTTTATAAGCGATTTTCAAAAAAATA
TAATGAAATAATGATACTTCGTGTTACTATAACTGGATTTGCTATATTTACGTTATTGTTTGGATGGTTAAACGAATCAA
ATGTAATTATATTATCAGTAATTATATTTATATTAGGTACTTGTGTTGGTATTGTGCCAGCTTTGCTGTCTACTATAATT
TCTAAAAGGTTTGAACATATAAAAGGGAAAGTGCTAGGTGTATTTAATTTTGTGAGATATATTGGAATGACTGTCGGTGC
ATTATTAATTGGTATCATTTCTCAGCCGTTGGTAGCCTTTTACTTCACAACTATAACTATCATGTTAATAGTAATATTTC
TTTATATAAAGATAGTTGACTTTCAGCTAAAGTATGCCAAATAA

Upstream 100 bases:

>100_bases
TATGAAGAGGTACTTAAAGTCTTTGATGATGATGAAATGGCAGTTATTATAGAGTTTTTAAACCGTAGTATAGAAGAATT
AAAAAAAGAAGATGGTTTAA

Downstream 100 bases:

>100_bases
ACTTAAAAAAGCAGTGAATCATTTCAATAGATGGAATGATTCACTGCTTTTTGTTTATAGAAATTTAAAATTCATGCCTT
TATGCTAACAACAATATTAT

Product: drug transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MINSNIRLYILGFLAFFASLIQNIYTPIIPRLYDDFQVPLFWINATVGGFIFIVAVMQIVLGRSIDSRDSKKVLLTGLGI
VIISSFICAVTHNFILFAISRLFQAIGCGIIPLVTLTLLAKLSTDNGRAQAMANYQIFLSCAPALAPILGSTLGARWDYI
GIFSFLLVISIVLFLIIFFIDIPNVEKGIVKLTEKIEEKYLTDKVFITLVTLGFLIFFTYFSILVYLPTLLNNTYDIGVG
ISGVLFLPITVSVILGSLFYKRFSKKYNEIMILRVTITGFAIFTLLFGWLNESNVIILSVIIFILGTCVGIVPALLSTII
SKRFEHIKGKVLGVFNFVRYIGMTVGALLIGIISQPLVAFYFTTITIMLIVIFLYIKIVDFQLKYAK

Sequences:

>Translated_387_residues
MINSNIRLYILGFLAFFASLIQNIYTPIIPRLYDDFQVPLFWINATVGGFIFIVAVMQIVLGRSIDSRDSKKVLLTGLGI
VIISSFICAVTHNFILFAISRLFQAIGCGIIPLVTLTLLAKLSTDNGRAQAMANYQIFLSCAPALAPILGSTLGARWDYI
GIFSFLLVISIVLFLIIFFIDIPNVEKGIVKLTEKIEEKYLTDKVFITLVTLGFLIFFTYFSILVYLPTLLNNTYDIGVG
ISGVLFLPITVSVILGSLFYKRFSKKYNEIMILRVTITGFAIFTLLFGWLNESNVIILSVIIFILGTCVGIVPALLSTII
SKRFEHIKGKVLGVFNFVRYIGMTVGALLIGIISQPLVAFYFTTITIMLIVIFLYIKIVDFQLKYAK
>Mature_387_residues
MINSNIRLYILGFLAFFASLIQNIYTPIIPRLYDDFQVPLFWINATVGGFIFIVAVMQIVLGRSIDSRDSKKVLLTGLGI
VIISSFICAVTHNFILFAISRLFQAIGCGIIPLVTLTLLAKLSTDNGRAQAMANYQIFLSCAPALAPILGSTLGARWDYI
GIFSFLLVISIVLFLIIFFIDIPNVEKGIVKLTEKIEEKYLTDKVFITLVTLGFLIFFTYFSILVYLPTLLNNTYDIGVG
ISGVLFLPITVSVILGSLFYKRFSKKYNEIMILRVTITGFAIFTLLFGWLNESNVIILSVIIFILGTCVGIVPALLSTII
SKRFEHIKGKVLGVFNFVRYIGMTVGALLIGIISQPLVAFYFTTITIMLIVIFLYIKIVDFQLKYAK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=379, Percent_Identity=23.2189973614776, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43231; Mature: 43231

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50850 MFS ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINSNIRLYILGFLAFFASLIQNIYTPIIPRLYDDFQVPLFWINATVGGFIFIVAVMQIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEHHHHHHHHHHHHHHHHH
LGRSIDSRDSKKVLLTGLGIVIISSFICAVTHNFILFAISRLFQAIGCGIIPLVTLTLLA
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KLSTDNGRAQAMANYQIFLSCAPALAPILGSTLGARWDYIGIFSFLLVISIVLFLIIFFI
HHCCCCCHHHHHHHHHHEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
DIPNVEKGIVKLTEKIEEKYLTDKVFITLVTLGFLIFFTYFSILVYLPTLLNNTYDIGVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
ISGVLFLPITVSVILGSLFYKRFSKKYNEIMILRVTITGFAIFTLLFGWLNESNVIILSV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHCCCCCHHHHH
IIFILGTCVGIVPALLSTIISKRFEHIKGKVLGVFNFVRYIGMTVGALLIGIISQPLVAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFTTITIMLIVIFLYIKIVDFQLKYAK
HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MINSNIRLYILGFLAFFASLIQNIYTPIIPRLYDDFQVPLFWINATVGGFIFIVAVMQIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEHHHHHHHHHHHHHHHHH
LGRSIDSRDSKKVLLTGLGIVIISSFICAVTHNFILFAISRLFQAIGCGIIPLVTLTLLA
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KLSTDNGRAQAMANYQIFLSCAPALAPILGSTLGARWDYIGIFSFLLVISIVLFLIIFFI
HHCCCCCHHHHHHHHHHEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
DIPNVEKGIVKLTEKIEEKYLTDKVFITLVTLGFLIFFTYFSILVYLPTLLNNTYDIGVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
ISGVLFLPITVSVILGSLFYKRFSKKYNEIMILRVTITGFAIFTLLFGWLNESNVIILSV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHCCCCCHHHHH
IIFILGTCVGIVPALLSTIISKRFEHIKGKVLGVFNFVRYIGMTVGALLIGIISQPLVAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFTTITIMLIVIFLYIKIVDFQLKYAK
HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]