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The map label for this gene is trxB2

Identifier: 41410437

GI number: 41410437

Start: 4819935

End: 4820945

Strand: Direct

Name: trxB2

Synonym: MAP4339

Alternate gene names: 41410437

Gene position: 4819935-4820945 (Clockwise)

Preceding gene: 41410436

Following gene: 41410438

Centisome position: 99.8

GC content: 68.74

Gene sequence:

>1011_bases
ATGACCGCCGACACTGTCCACGACGTGATCATCATTGGTTCGGGTCCCGCGGGCTACACCGCCGCGTTGTACACCGCGCG
GGCGCAGCTGGCGCCGGTGGTGTTCGAGGGGACCTCGTTCGGTGGGGCGTTGATGACCACCACCGAGGTGGAGAACTACC
CCGGTTTCCGCGACGGGATCACGGGCCCGGAGTTGATGGATCAGATGCGTGAGCAGGCGCTGCGGTTCGGCGCCGATCTG
CGGATGGAAGACGTCGAGTCGGTCTCGCTGGCCGGTCCGGTCAAGTCGGTGACGACGGCCGAGGGTGAGACGGTGCGGGC
GCGGGCGGTGATCCTGGCCATGGGCGCCGCCGCGCGGTATCTCGGTGTGCCCGGCGAGCAGGACCTGCTGGGGCGCGGTG
TCAGTTCGTGTGCGACGTGCGACGGGTTCTTCTTCAAGGACCAGGACATCGCGGTCATCGGGGGCGGGGATTCGGCGATG
GAGGAGGCCACGTTCCTGACGCGGTTCGCCCGCAGCGTCACGCTGGTGCACCGCCGCGAGGAGTTCCGGGCGTCGCGGAT
CATGCTGGAGCGGGCGCGCGCCAACGACAAGATCACCATCGTGACCAACAAGGCGGTCGAGGCGGTAGAGGGCTCGGAGA
CGGTGACGGGTTTGCGGTTGCGCGACACGGTCACCGGCGAGACGTCGACGTTGGCGGTCACCGGGGTGTTCGTGGCGATC
GGTCACGACCCGCGTTCGGAGCTGGTGCGCGACGTGCTGGACACCGACCCCGACGGCTATGTGTTGGTGCAGGGCCGCAC
CACGGCCACCTCGATTCCGGGGGTGTTCGCCGCCGGGGACCTGGTGGACCGCACCTACCGTCAGGCCGTCACCGCCGCCG
GCAGCGGTTGCGCGGCGGCTATCGACGCCGAACGCTGGCTCGCCGAACATGCCGAGTCCAGTGCGGCCGCGCAAGGCGAT
GCCACCGAATTCCCGGGCAGTACCGACACATTGATTGGAGCACCGCAATGA

Upstream 100 bases:

>100_bases
GGTGCAAGGGGTGCCGGCCGTGTTGTTCGCGACAGCGGGGAACAGCCATCCCTACCCTGGCGTTTATACCGATCCAGAGA
CCATCGCTCGAAAGGTTTTC

Downstream 100 bases:

>100_bases
CCGACGCCGAAAAGGCCAGCGCCACAATAGAAGTCTCCGACGCATCGTTTTCCACCGATGTGTTGGCCAGCAATAAGCCT
GTGCTGGTTGACTTTTGGGC

Product: hypothetical protein

Products: NA

Alternate protein names: TR; TRXR [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTADTVHDVIIIGSGPAGYTAALYTARAQLAPVVFEGTSFGGALMTTTEVENYPGFRDGITGPELMDQMREQALRFGADL
RMEDVESVSLAGPVKSVTTAEGETVRARAVILAMGAAARYLGVPGEQDLLGRGVSSCATCDGFFFKDQDIAVIGGGDSAM
EEATFLTRFARSVTLVHRREEFRASRIMLERARANDKITIVTNKAVEAVEGSETVTGLRLRDTVTGETSTLAVTGVFVAI
GHDPRSELVRDVLDTDPDGYVLVQGRTTATSIPGVFAAGDLVDRTYRQAVTAAGSGCAAAIDAERWLAEHAESSAAAQGD
ATEFPGSTDTLIGAPQ

Sequences:

>Translated_336_residues
MTADTVHDVIIIGSGPAGYTAALYTARAQLAPVVFEGTSFGGALMTTTEVENYPGFRDGITGPELMDQMREQALRFGADL
RMEDVESVSLAGPVKSVTTAEGETVRARAVILAMGAAARYLGVPGEQDLLGRGVSSCATCDGFFFKDQDIAVIGGGDSAM
EEATFLTRFARSVTLVHRREEFRASRIMLERARANDKITIVTNKAVEAVEGSETVTGLRLRDTVTGETSTLAVTGVFVAI
GHDPRSELVRDVLDTDPDGYVLVQGRTTATSIPGVFAAGDLVDRTYRQAVTAAGSGCAAAIDAERWLAEHAESSAAAQGD
ATEFPGSTDTLIGAPQ
>Mature_335_residues
TADTVHDVIIIGSGPAGYTAALYTARAQLAPVVFEGTSFGGALMTTTEVENYPGFRDGITGPELMDQMREQALRFGADLR
MEDVESVSLAGPVKSVTTAEGETVRARAVILAMGAAARYLGVPGEQDLLGRGVSSCATCDGFFFKDQDIAVIGGGDSAME
EATFLTRFARSVTLVHRREEFRASRIMLERARANDKITIVTNKAVEAVEGSETVTGLRLRDTVTGETSTLAVTGVFVAIG
HDPRSELVRDVLDTDPDGYVLVQGRTTATSIPGVFAAGDLVDRTYRQAVTAAGSGCAAAIDAERWLAEHAESSAAAQGDA
TEFPGSTDTLIGAPQ

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=308, Percent_Identity=49.3506493506493, Blast_Score=294, Evalue=6e-81,
Organism=Escherichia coli, GI87081763, Length=311, Percent_Identity=33.4405144694534, Blast_Score=152, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=47.7707006369427, Blast_Score=288, Evalue=9e-79,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=44.7284345047923, Blast_Score=270, Evalue=2e-73,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35334; Mature: 35203

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADTVHDVIIIGSGPAGYTAALYTARAQLAPVVFEGTSFGGALMTTTEVENYPGFRDGI
CCCCCEEEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCCCCEEEEEEECCCCCCCCCCC
TGPELMDQMREQALRFGADLRMEDVESVSLAGPVKSVTTAEGETVRARAVILAMGAAARY
CCHHHHHHHHHHHHHHCCCCCHHHHHHHECCCCCCHHCCCCCCEEEHEEEEEEHHHHHHH
LGVPGEQDLLGRGVSSCATCDGFFFKDQDIAVIGGGDSAMEEATFLTRFARSVTLVHRRE
CCCCCCHHHHHCCHHHHHCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
EFRASRIMLERARANDKITIVTNKAVEAVEGSETVTGLRLRDTVTGETSTLAVTGVFVAI
HHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCEEEEEEEEECCCCCCEEEEEEEEEEE
GHDPRSELVRDVLDTDPDGYVLVQGRTTATSIPGVFAAGDLVDRTYRQAVTAAGSGCAAA
CCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
IDAERWLAEHAESSAAAQGDATEFPGSTDTLIGAPQ
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCC
>Mature Secondary Structure 
TADTVHDVIIIGSGPAGYTAALYTARAQLAPVVFEGTSFGGALMTTTEVENYPGFRDGI
CCCCEEEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCCCCEEEEEEECCCCCCCCCCC
TGPELMDQMREQALRFGADLRMEDVESVSLAGPVKSVTTAEGETVRARAVILAMGAAARY
CCHHHHHHHHHHHHHHCCCCCHHHHHHHECCCCCCHHCCCCCCEEEHEEEEEEHHHHHHH
LGVPGEQDLLGRGVSSCATCDGFFFKDQDIAVIGGGDSAMEEATFLTRFARSVTLVHRRE
CCCCCCHHHHHCCHHHHHCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
EFRASRIMLERARANDKITIVTNKAVEAVEGSETVTGLRLRDTVTGETSTLAVTGVFVAI
HHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCEEEEEEEEECCCCCCEEEEEEEEEEE
GHDPRSELVRDVLDTDPDGYVLVQGRTTATSIPGVFAAGDLVDRTYRQAVTAAGSGCAAA
CCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
IDAERWLAEHAESSAAAQGDATEFPGSTDTLIGAPQ
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]