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The map label for this gene is 41410274

Identifier: 41410274

GI number: 41410274

Start: 4650264

End: 4651766

Strand: Direct

Name: 41410274

Synonym: MAP4176

Alternate gene names: NA

Gene position: 4650264-4651766 (Clockwise)

Preceding gene: 41410273

Following gene: 41410275

Centisome position: 96.28

GC content: 73.99

Gene sequence:

>1503_bases
ATGTTCGAAGACGCGGTCGCCTGGTTCGACGAGCTGATGGAGCGGTGCTACCCGTCGGCGACGCCGGAGTCGGCGGCGCT
GGTGCAGCGGATCGGTGTCTTCGCGCGGGTGGAGAATCGGGCGGCGGCCGAGCAGTTGGCGGCCATTGGGGAGCTGTTCG
CCTATCGGCTGTCGCGCTGCTCGGAGTGCGAGGACTGGGCGGTCGACACCGAGGCCGCGGTGAGCGCGGAGGTGGCGGCC
CAGCTGCGGATCGGGCAGGGGTTGGCCGCCGCCAAGGTGCGCTACGCACGGGCAATGCGCGAACGGCTGCCCCGGGTGGG
TGAGGTCTTTCGGGCCGGGGAGATCGACTTCCGGCTGTTCGCAACGATCGTGTATCGCACCGATCTGATCACCGATCGCC
GGGTGCTGGCGGCCGTGGACGCCGAGTTGGCCGCGACGGCGGCGCGCTGGCCGTCGATGACCCGGGCGCGGTTGGCCGCC
CGGGTGGACGCGGTGGTGGCCAAGGCCGACGCCGACGCGGTGCGGCGCGCCGAGAAGCAGGCGGCGACCCGCCACGTCTG
GATCGCCGAGATGGGTGAGGGCCTGTCGCATCTGGAGGGCACGGTGTCGAGTCCCGACGCGCACGCGCTGGACAAACGGC
TGGATGCGTTGGCCGCCACGGTGTGCGAGCACGACCCGCGCACTGGTGAGCAGCGCCGCGCCGACGCGCTGGGGGCGCTG
GCCGCCGGGGCCGACCGGTTGGGCTGCCGGTGTGGCCGCGCCGATTGTGCGGCCGGTACGGGGCCCGCCGCCGGGCCGGT
GGTGATCCACGTGATCGCCGAGCGGGCCAGCGTCGAGGGCACCGGCGGCGGGCCGGCGGTCGAGGTCGGCGCCGAGGGTC
TCCTCCCGGCGCAGCTGGTCGCCGAGCTGGCCGCGTCGGCCAGGCTGATGCCGCTGGTCCACCCCGCCGATTCGTCTCCG
GAGAACCGGTACACGCCGTCGGCGGCGCTGGCCGACTTCGTGCGCTGCCGGGATTTGACCTGCCGCTGGCCCGGCTGCGA
CCGCCCGGCCACCGAGTGCGACCTGGACCATACGATTCCCTACGCCGAGGGCGGGCCCACCCACGCGTCAAACCTCAAGT
GCTACTGCAGAACTCACCATTTGGTGAAGACCTTCTGGGGCTGGCGGGAACAACAGCTGCCGGATGCGACGCTGATCCTG
ACCTCGCCGGCGGGGCAGACCTATGTCACCACCCCGGGCAGCGCGCTGCTGTTCCCGTCGTTGTGCGTGCCCACCGGTGA
GCCGGCCCGGCCGGTCGCGGCCGGATCCCAGCCCTGCGGTGAGCGCACCGCGATGATGCCCACCCGCCGGCGCACCCGCG
GCCAAAATCGCGCCGCCCGGGTGGCCGCCGAACGCCGGGCCAACCGCGCCGCCCGGCTGGCCCGGGCAACTCGGCCGGCC
CCTGCGGCGAGCCAGTCCTGGCCGGCCGGCCATGGGCCCGACGCCGACCCGCCGCCGTTCTAG

Upstream 100 bases:

>100_bases
GCAGGGCGACTGACCGCCGCGTACGCCAGGTGCGCCGGTTATCCACAGGTCGCGGTCCTGCCAAGCGCCCGAGTCGGCGG
ACAGTGCTACTCTCGCACAT

Downstream 100 bases:

>100_bases
CTGCTCTAGCTGCGAAATCTCGCCGGCTGAGAACCCTGCACCCGGAATTTGGCTCTGAGCTGGTCGTCCCCTAGACTCTA
GGGGTTGCCTTGGGCAGACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MFEDAVAWFDELMERCYPSATPESAALVQRIGVFARVENRAAAEQLAAIGELFAYRLSRCSECEDWAVDTEAAVSAEVAA
QLRIGQGLAAAKVRYARAMRERLPRVGEVFRAGEIDFRLFATIVYRTDLITDRRVLAAVDAELAATAARWPSMTRARLAA
RVDAVVAKADADAVRRAEKQAATRHVWIAEMGEGLSHLEGTVSSPDAHALDKRLDALAATVCEHDPRTGEQRRADALGAL
AAGADRLGCRCGRADCAAGTGPAAGPVVIHVIAERASVEGTGGGPAVEVGAEGLLPAQLVAELAASARLMPLVHPADSSP
ENRYTPSAALADFVRCRDLTCRWPGCDRPATECDLDHTIPYAEGGPTHASNLKCYCRTHHLVKTFWGWREQQLPDATLIL
TSPAGQTYVTTPGSALLFPSLCVPTGEPARPVAAGSQPCGERTAMMPTRRRTRGQNRAARVAAERRANRAARLARATRPA
PAASQSWPAGHGPDADPPPF

Sequences:

>Translated_500_residues
MFEDAVAWFDELMERCYPSATPESAALVQRIGVFARVENRAAAEQLAAIGELFAYRLSRCSECEDWAVDTEAAVSAEVAA
QLRIGQGLAAAKVRYARAMRERLPRVGEVFRAGEIDFRLFATIVYRTDLITDRRVLAAVDAELAATAARWPSMTRARLAA
RVDAVVAKADADAVRRAEKQAATRHVWIAEMGEGLSHLEGTVSSPDAHALDKRLDALAATVCEHDPRTGEQRRADALGAL
AAGADRLGCRCGRADCAAGTGPAAGPVVIHVIAERASVEGTGGGPAVEVGAEGLLPAQLVAELAASARLMPLVHPADSSP
ENRYTPSAALADFVRCRDLTCRWPGCDRPATECDLDHTIPYAEGGPTHASNLKCYCRTHHLVKTFWGWREQQLPDATLIL
TSPAGQTYVTTPGSALLFPSLCVPTGEPARPVAAGSQPCGERTAMMPTRRRTRGQNRAARVAAERRANRAARLARATRPA
PAASQSWPAGHGPDADPPPF
>Mature_500_residues
MFEDAVAWFDELMERCYPSATPESAALVQRIGVFARVENRAAAEQLAAIGELFAYRLSRCSECEDWAVDTEAAVSAEVAA
QLRIGQGLAAAKVRYARAMRERLPRVGEVFRAGEIDFRLFATIVYRTDLITDRRVLAAVDAELAATAARWPSMTRARLAA
RVDAVVAKADADAVRRAEKQAATRHVWIAEMGEGLSHLEGTVSSPDAHALDKRLDALAATVCEHDPRTGEQRRADALGAL
AAGADRLGCRCGRADCAAGTGPAAGPVVIHVIAERASVEGTGGGPAVEVGAEGLLPAQLVAELAASARLMPLVHPADSSP
ENRYTPSAALADFVRCRDLTCRWPGCDRPATECDLDHTIPYAEGGPTHASNLKCYCRTHHLVKTFWGWREQQLPDATLIL
TSPAGQTYVTTPGSALLFPSLCVPTGEPARPVAAGSQPCGERTAMMPTRRRTRGQNRAARVAAERRANRAARLARATRPA
PAASQSWPAGHGPDADPPPF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv3776 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003870
- InterPro:   IPR003615 [H]

Pfam domain/function: PF02720 DUF222 [H]

EC number: NA

Molecular weight: Translated: 53429; Mature: 53429

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEDAVAWFDELMERCYPSATPESAALVQRIGVFARVENRAAAEQLAAIGELFAYRLSRC
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SECEDWAVDTEAAVSAEVAAQLRIGQGLAAAKVRYARAMRERLPRVGEVFRAGEIDFRLF
CCCHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHH
ATIVYRTDLITDRRVLAAVDAELAATAARWPSMTRARLAARVDAVVAKADADAVRRAEKQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AATRHVWIAEMGEGLSHLEGTVSSPDAHALDKRLDALAATVCEHDPRTGEQRRADALGAL
HHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AAGADRLGCRCGRADCAAGTGPAAGPVVIHVIAERASVEGTGGGPAVEVGAEGLLPAQLV
HHCCHHHCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCEEECCCCCCCHHHHH
AELAASARLMPLVHPADSSPENRYTPSAALADFVRCRDLTCRWPGCDRPATECDLDHTIP
HHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
YAEGGPTHASNLKCYCRTHHLVKTFWGWREQQLPDATLILTSPAGQTYVTTPGSALLFPS
CCCCCCCCCCCCEEEHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCEEEECCCCHHHCCH
LCVPTGEPARPVAAGSQPCGERTAMMPTRRRTRGQNRAARVAAERRANRAARLARATRPA
HCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PAASQSWPAGHGPDADPPPF
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFEDAVAWFDELMERCYPSATPESAALVQRIGVFARVENRAAAEQLAAIGELFAYRLSRC
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SECEDWAVDTEAAVSAEVAAQLRIGQGLAAAKVRYARAMRERLPRVGEVFRAGEIDFRLF
CCCHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHH
ATIVYRTDLITDRRVLAAVDAELAATAARWPSMTRARLAARVDAVVAKADADAVRRAEKQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AATRHVWIAEMGEGLSHLEGTVSSPDAHALDKRLDALAATVCEHDPRTGEQRRADALGAL
HHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AAGADRLGCRCGRADCAAGTGPAAGPVVIHVIAERASVEGTGGGPAVEVGAEGLLPAQLV
HHCCHHHCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCEEECCCCCCCHHHHH
AELAASARLMPLVHPADSSPENRYTPSAALADFVRCRDLTCRWPGCDRPATECDLDHTIP
HHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
YAEGGPTHASNLKCYCRTHHLVKTFWGWREQQLPDATLILTSPAGQTYVTTPGSALLFPS
CCCCCCCCCCCCEEEHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCEEEECCCCHHHCCH
LCVPTGEPARPVAAGSQPCGERTAMMPTRRRTRGQNRAARVAAERRANRAARLARATRPA
HCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PAASQSWPAGHGPDADPPPF
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]