Click here to switch to the map view.

The map label for this gene is lpqL_1

Identifier: 41410004

GI number: 41410004

Start: 4368100

End: 4369596

Strand: Direct

Name: lpqL_1

Synonym: MAP3906

Alternate gene names: 41410004

Gene position: 4368100-4369596 (Clockwise)

Preceding gene: 41410003

Following gene: 41410005

Centisome position: 90.44

GC content: 69.21

Gene sequence:

>1497_bases
ATGGTGAACAAATTCACGACATTTCCGGCGCTGCTCGCGGTGGTCGCCCTGACCGCGTTGGCCACCGGCTGCGGGCACCG
CTCCTCCGGCGCGGGCCAAACCACCGGGGACCCCGCCGCGGCCGAGTTCGCGTCCGGGTTGCGCAACAAGGTCACCACCG
ACGCGATGATGACCCACCTGACCAAGCTGCAAGACATCGCCAACGCCAACAACGGCACCCGGGCGGTCGGCACACCCGGC
TACGAGGCGAGCGTCGACTACGTGGTGAAAACCTTGCGCGACAGCGGGTTCAACGTGCAGACCCCGGAGTTCTCGGCCCG
GGTGTTCCACGCCGAAAAGCCCGATCTCACCGTCGGCGGCAGGCCGGTGGAGGCCCATGCACTGGACTTCAGCCTGGGCA
CCGGGCCCGACGGGGTGAGCGGCCCGCTGGTCGCCGCCCCGCCCAACAACCCCGGGTGCGCGGTCACCGACTACGGCAGC
CTGCCGGTGCAGGGCGCGGTGATCCTGCTCGACCGCGGCACGTGCCCGTTCGCGCAGAAGGAAGATGTCGCCGCGCAGCG
CGGCGCGGTGGCGTTGATCATCGCCGACAACGTCGACGAACAACAGATGGGCGGCACGCTCGGGCCGTCGACCGAGGTGA
AGATCCCGGTGCTGAGCGTGACAAAGTCCGTCGGGGTGCAGCTGCGCGGGCAGCCCGGGCCCACCACCATCAAGCTCACG
GCCAGCGCGCAAAGCTTCAAGGCGCGCAACGTGATCGCGCAGACCAAGACCGGATCGGAGCACGACGTGGTGATGGCCGG
GGCGCACCTGGACAGCGTGCCCGAGGGCCCGGGCATCAACGACAACGGGTCGGGCGTGGCCGCGGTGCTGGAATCCGCTG
TGCGACTGGGCAGTTCGCCTCCGGTGCACAACGCGGTGCGGTTCGGGTTCTGGGGCGCCGAGGAGCTCGGGCTGATCGGG
TCGCGCAACTACGTCGAGTCGCTGGACTTGACCGCGCTGAAAAACATTGCGCTGTACCTGAATTTCGACATGCTCGCCTC
GCCGAACCCCGGCTACTTCACCTACGGCGGCGACCAGTCGCTGCCGATGGACGCCCGCGGCCAACCGGTGGTGCCCGAAG
GGTCGGCGGGCATCGAGCGCACGCTGGTGGCCTACCTGAAGTCGGCCGGCAAGACCGCACAGGACACCTCGTTCGACGGC
CGGTCGGATTACGACGGGTTCACCCTGGCGGGGATTCCGGCCGGCGGGCTGTTCTCCGGCGCCGAGGGGAAGATGTCCGC
CGATCAGGCCAAGCTGTGGGGCGGAACCGCCGACCAGCCGTTCGACCCCAACTACCACCAGAAGACCGACACCCTCGACC
ACATCGACCGCACCGCGCTGGGGATCAACGGGGGCGGGGTGGCCTACGCGATCGGTCTCTACGCCCAAGACCTCGGCGGC
CACAACGGCGTCCCCGCCATGGCCGACCGCACCCGGCACGTGCTCGCCAAGTCATGA

Upstream 100 bases:

>100_bases
TGGTGCGCAACATCCCGGTGGCGCCGTTCACCGCGCTGCATGTCTGAGGACGCCGTGTCCTGAATCCGCCCACCCGGGCC
GCGGTCTAACCTGGGGCGCG

Downstream 100 bases:

>100_bases
CCGTCCGGCTGGGCGCGACGCTGCTGTGGATCGCCGTGCTGCTGGCCGGTTGCTCGTCGGCGGGGCCCGGACTGCCGACC
GCGGCACCCGATTTGGGCCA

Product: LpqL_1

Products: NA

Alternate protein names: LIE1 [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MVNKFTTFPALLAVVALTALATGCGHRSSGAGQTTGDPAAAEFASGLRNKVTTDAMMTHLTKLQDIANANNGTRAVGTPG
YEASVDYVVKTLRDSGFNVQTPEFSARVFHAEKPDLTVGGRPVEAHALDFSLGTGPDGVSGPLVAAPPNNPGCAVTDYGS
LPVQGAVILLDRGTCPFAQKEDVAAQRGAVALIIADNVDEQQMGGTLGPSTEVKIPVLSVTKSVGVQLRGQPGPTTIKLT
ASAQSFKARNVIAQTKTGSEHDVVMAGAHLDSVPEGPGINDNGSGVAAVLESAVRLGSSPPVHNAVRFGFWGAEELGLIG
SRNYVESLDLTALKNIALYLNFDMLASPNPGYFTYGGDQSLPMDARGQPVVPEGSAGIERTLVAYLKSAGKTAQDTSFDG
RSDYDGFTLAGIPAGGLFSGAEGKMSADQAKLWGGTADQPFDPNYHQKTDTLDHIDRTALGINGGGVAYAIGLYAQDLGG
HNGVPAMADRTRHVLAKS

Sequences:

>Translated_498_residues
MVNKFTTFPALLAVVALTALATGCGHRSSGAGQTTGDPAAAEFASGLRNKVTTDAMMTHLTKLQDIANANNGTRAVGTPG
YEASVDYVVKTLRDSGFNVQTPEFSARVFHAEKPDLTVGGRPVEAHALDFSLGTGPDGVSGPLVAAPPNNPGCAVTDYGS
LPVQGAVILLDRGTCPFAQKEDVAAQRGAVALIIADNVDEQQMGGTLGPSTEVKIPVLSVTKSVGVQLRGQPGPTTIKLT
ASAQSFKARNVIAQTKTGSEHDVVMAGAHLDSVPEGPGINDNGSGVAAVLESAVRLGSSPPVHNAVRFGFWGAEELGLIG
SRNYVESLDLTALKNIALYLNFDMLASPNPGYFTYGGDQSLPMDARGQPVVPEGSAGIERTLVAYLKSAGKTAQDTSFDG
RSDYDGFTLAGIPAGGLFSGAEGKMSADQAKLWGGTADQPFDPNYHQKTDTLDHIDRTALGINGGGVAYAIGLYAQDLGG
HNGVPAMADRTRHVLAKS
>Mature_498_residues
MVNKFTTFPALLAVVALTALATGCGHRSSGAGQTTGDPAAAEFASGLRNKVTTDAMMTHLTKLQDIANANNGTRAVGTPG
YEASVDYVVKTLRDSGFNVQTPEFSARVFHAEKPDLTVGGRPVEAHALDFSLGTGPDGVSGPLVAAPPNNPGCAVTDYGS
LPVQGAVILLDRGTCPFAQKEDVAAQRGAVALIIADNVDEQQMGGTLGPSTEVKIPVLSVTKSVGVQLRGQPGPTTIKLT
ASAQSFKARNVIAQTKTGSEHDVVMAGAHLDSVPEGPGINDNGSGVAAVLESAVRLGSSPPVHNAVRFGFWGAEELGLIG
SRNYVESLDLTALKNIALYLNFDMLASPNPGYFTYGGDQSLPMDARGQPVVPEGSAGIERTLVAYLKSAGKTAQDTSFDG
RSDYDGFTLAGIPAGGLFSGAEGKMSADQAKLWGGTADQPFDPNYHQKTDTLDHIDRTALGINGGGVAYAIGLYAQDLGG
HNGVPAMADRTRHVLAKS

Specific function: A leucine-specific metalloprotease that plays a role in controlling the amount of leupeptin during colony development. Degrades leupeptin into three components, acetyl-leucine, leucine and argininal [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28A subfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319763, Length=458, Percent_Identity=31.6593886462882, Blast_Score=200, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR007484
- InterPro:   IPR002884 [H]

Pfam domain/function: PF01483 P_proprotein; PF04389 Peptidase_M28 [H]

EC number: 3.4.11.- [C]

Molecular weight: Translated: 51460; Mature: 51460

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKFTTFPALLAVVALTALATGCGHRSSGAGQTTGDPAAAEFASGLRNKVTTDAMMTHL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TKLQDIANANNGTRAVGTPGYEASVDYVVKTLRDSGFNVQTPEFSARVFHAEKPDLTVGG
HHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCEEECC
RPVEAHALDFSLGTGPDGVSGPLVAAPPNNPGCAVTDYGSLPVQGAVILLDRGTCPFAQK
CCEEEEEEEEECCCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCC
EDVAAQRGAVALIIADNVDEQQMGGTLGPSTEVKIPVLSVTKSVGVQLRGQPGPTTIKLT
HHHHHHCCCEEEEEECCCCHHHHCCCCCCCCEEEEEHEEEHHCCCEEEECCCCCCEEEEE
ASAQSFKARNVIAQTKTGSEHDVVMAGAHLDSVPEGPGINDNGSGVAAVLESAVRLGSSP
ECCHHHHHHHHEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PVHNAVRFGFWGAEELGLIGSRNYVESLDLTALKNIALYLNFDMLASPNPGYFTYGGDQS
CCCHHEEECCCCHHHHCCCCCCHHHHHHHHHHHCCEEEEEEEEEECCCCCCEEEECCCCC
LPMDARGQPVVPEGSAGIERTLVAYLKSAGKTAQDTSFDGRSDYDGFTLAGIPAGGLFSG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
AEGKMSADQAKLWGGTADQPFDPNYHQKTDTLDHIDRTALGINGGGVAYAIGLYAQDLGG
CCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHEECCCCCCEEEEEHHHHHCCC
HNGVPAMADRTRHVLAKS
CCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MVNKFTTFPALLAVVALTALATGCGHRSSGAGQTTGDPAAAEFASGLRNKVTTDAMMTHL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TKLQDIANANNGTRAVGTPGYEASVDYVVKTLRDSGFNVQTPEFSARVFHAEKPDLTVGG
HHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCEEECC
RPVEAHALDFSLGTGPDGVSGPLVAAPPNNPGCAVTDYGSLPVQGAVILLDRGTCPFAQK
CCEEEEEEEEECCCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCC
EDVAAQRGAVALIIADNVDEQQMGGTLGPSTEVKIPVLSVTKSVGVQLRGQPGPTTIKLT
HHHHHHCCCEEEEEECCCCHHHHCCCCCCCCEEEEEHEEEHHCCCEEEECCCCCCEEEEE
ASAQSFKARNVIAQTKTGSEHDVVMAGAHLDSVPEGPGINDNGSGVAAVLESAVRLGSSP
ECCHHHHHHHHEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PVHNAVRFGFWGAEELGLIGSRNYVESLDLTALKNIALYLNFDMLASPNPGYFTYGGDQS
CCCHHEEECCCCHHHHCCCCCCHHHHHHHHHHHCCEEEEEEEEEECCCCCCEEEECCCCC
LPMDARGQPVVPEGSAGIERTLVAYLKSAGKTAQDTSFDGRSDYDGFTLAGIPAGGLFSG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
AEGKMSADQAKLWGGTADQPFDPNYHQKTDTLDHIDRTALGINGGGVAYAIGLYAQDLGG
CCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHEECCCCCCEEEEEHHHHHCCC
HNGVPAMADRTRHVLAKS
CCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Aminopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA