Click here to switch to the map view.

The map label for this gene is lpqL_2

Identifier: 41410005

GI number: 41410005

Start: 4369632

End: 4371065

Strand: Direct

Name: lpqL_2

Synonym: MAP3907

Alternate gene names: 41410005

Gene position: 4369632-4371065 (Clockwise)

Preceding gene: 41410004

Following gene: 41410006

Centisome position: 90.47

GC content: 70.5

Gene sequence:

>1434_bases
GTGCTGCTGGCCGGTTGCTCGTCGGCGGGGCCCGGACTGCCGACCGCGGCACCCGATTTGGGCCACGGCCTGGCCAAGAA
GGTGACCGCCGACGCCATGATGGCCCACCTGCGCGCCTTGCAGAACATCGCCAACACCAACGGCGGCAACCGCGCGGACG
GCACCCCGGGCTTTCAGGCCAGCGTCGACTACGTGGCTAAAGCGCTGCGCGACAAGGGTTTCGACGTACAGACGCCGCAG
TTCGACCGGCTCTACCCGGTGTCCCCCGGCAAGCCGACGCTGACCGTCGCGGGCCGCGGCTACCCCGTCGACCAGGCCTC
GATGTTGGTCCAGACCCCGCCCGGCGGGCTGACCGGACCCGCCGTCCGCCCGGCCCAGCCGTCGGGTTGCGCGGCCAGCG
ACTACCCCGGCGCCCTGCCCAAGGGTGCGATCGCCGTCGTCGACGACACCCGCTGCTCGGTGGTCGACAAACAGAACAGC
GCGGTGGCCCGGGGCGCGAGCGCGCTGATCGTGGTGAGCGCACCCGACGGGCACGGCGCCCCGCCCACCTTGTTCACCCC
CGGCTACTACAAACAGCTGAGTGTGCCGGTGGCCGTCGTCAACCCGTCCGGCGCCGCCGCGCTGGCCGGTGCAGGCGGGC
CGGTGCGGTTAATCCTGGATGCAGTCAACGTCAAGGTCACGTCGCGAAACGTGGTGGCGCAGACCAAGACCGGGTCAGCC
CACGAGGTCGTCATGGTCGGTGCGCACCTGGACGGCTCGCGCGCCGGACCGGGCATCAACGACAACGGCTCCGGCGTGGC
CGCGGTGCTGGAAACCGCGCTGCAGCTGGGCCCGCTGGCGCCGGTAAGCAACGCGGTGCGGTTCGTGTTCTGGGGCGCCG
GGGAAGACGGACTGGGCGGCGTGATGGATTACCTGTTCGGCCTGGACCGCGACCAACTCAACGACATCGCGCTGTATCTG
AACTTCACCATGCTCGGCTCGCCCAACGCCGGGTTCTTCACCGACGACGGCGATCAGTCCGGGCCGCCGGCCCCCGGTAT
TTCGGCCGCCGACGTTCCCGAAGGGTCGGCCGGCATCGAGCGCACCCTGGCGGGCTATCTGAACCTGGCCGGGAAGCGTG
CGGCGGACATGCCCCTGAACACCCGGGCCGACTACCACCCCTTCATGGTGGCCGGTGTGCCGATCGGCGGCATGACCACC
GGAGCCTCGCAACCGAAAACCACTGTGCAGTCCCGGTTGTGGGGCGGCCAGGCCGGCGTGCCGTTCGATCCGAACTTCCA
AAGCCCCCGCGACACCGCCGACAACATCAACCGGGACGCCCTGGCGGTGATGGGTTCCGGCGTCGGGTTCGCGGTTGGCA
GCTACGCCCAATCGATCGGCGGGGTCAACGGGGTGCCGCCGCACGACAAGCGGCATCGCACCCGAGTGCCCTGA

Upstream 100 bases:

>100_bases
TCGGCGGCCACAACGGCGTCCCCGCCATGGCCGACCGCACCCGGCACGTGCTCGCCAAGTCATGACCGTCCGGCTGGGCG
CGACGCTGCTGTGGATCGCC

Downstream 100 bases:

>100_bases
CCGCGGCACAACGAGTTACGCCGGCACGCCGAAGGGTGAGAAATCGCGAGATCCCTTGAAGGGAGCCAGCGCCTTTCTTG
CCCCCGGCGACGGCCGGTCG

Product: LpqL_2

Products: NA

Alternate protein names: LIE2 [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MLLAGCSSAGPGLPTAAPDLGHGLAKKVTADAMMAHLRALQNIANTNGGNRADGTPGFQASVDYVAKALRDKGFDVQTPQ
FDRLYPVSPGKPTLTVAGRGYPVDQASMLVQTPPGGLTGPAVRPAQPSGCAASDYPGALPKGAIAVVDDTRCSVVDKQNS
AVARGASALIVVSAPDGHGAPPTLFTPGYYKQLSVPVAVVNPSGAAALAGAGGPVRLILDAVNVKVTSRNVVAQTKTGSA
HEVVMVGAHLDGSRAGPGINDNGSGVAAVLETALQLGPLAPVSNAVRFVFWGAGEDGLGGVMDYLFGLDRDQLNDIALYL
NFTMLGSPNAGFFTDDGDQSGPPAPGISAADVPEGSAGIERTLAGYLNLAGKRAADMPLNTRADYHPFMVAGVPIGGMTT
GASQPKTTVQSRLWGGQAGVPFDPNFQSPRDTADNINRDALAVMGSGVGFAVGSYAQSIGGVNGVPPHDKRHRTRVP

Sequences:

>Translated_477_residues
MLLAGCSSAGPGLPTAAPDLGHGLAKKVTADAMMAHLRALQNIANTNGGNRADGTPGFQASVDYVAKALRDKGFDVQTPQ
FDRLYPVSPGKPTLTVAGRGYPVDQASMLVQTPPGGLTGPAVRPAQPSGCAASDYPGALPKGAIAVVDDTRCSVVDKQNS
AVARGASALIVVSAPDGHGAPPTLFTPGYYKQLSVPVAVVNPSGAAALAGAGGPVRLILDAVNVKVTSRNVVAQTKTGSA
HEVVMVGAHLDGSRAGPGINDNGSGVAAVLETALQLGPLAPVSNAVRFVFWGAGEDGLGGVMDYLFGLDRDQLNDIALYL
NFTMLGSPNAGFFTDDGDQSGPPAPGISAADVPEGSAGIERTLAGYLNLAGKRAADMPLNTRADYHPFMVAGVPIGGMTT
GASQPKTTVQSRLWGGQAGVPFDPNFQSPRDTADNINRDALAVMGSGVGFAVGSYAQSIGGVNGVPPHDKRHRTRVP
>Mature_477_residues
MLLAGCSSAGPGLPTAAPDLGHGLAKKVTADAMMAHLRALQNIANTNGGNRADGTPGFQASVDYVAKALRDKGFDVQTPQ
FDRLYPVSPGKPTLTVAGRGYPVDQASMLVQTPPGGLTGPAVRPAQPSGCAASDYPGALPKGAIAVVDDTRCSVVDKQNS
AVARGASALIVVSAPDGHGAPPTLFTPGYYKQLSVPVAVVNPSGAAALAGAGGPVRLILDAVNVKVTSRNVVAQTKTGSA
HEVVMVGAHLDGSRAGPGINDNGSGVAAVLETALQLGPLAPVSNAVRFVFWGAGEDGLGGVMDYLFGLDRDQLNDIALYL
NFTMLGSPNAGFFTDDGDQSGPPAPGISAADVPEGSAGIERTLAGYLNLAGKRAADMPLNTRADYHPFMVAGVPIGGMTT
GASQPKTTVQSRLWGGQAGVPFDPNFQSPRDTADNINRDALAVMGSGVGFAVGSYAQSIGGVNGVPPHDKRHRTRVP

Specific function: A leucine-specific metalloprotease that plays a role in controlling the amount of leupeptin during colony development. Degrades leupeptin into three components, acetyl-leucine, leucine and argininal [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28A subfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319763, Length=461, Percent_Identity=26.2472885032538, Blast_Score=140, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005075
- InterPro:   IPR007484
- InterPro:   IPR013856
- InterPro:   IPR001570
- InterPro:   IPR008757
- InterPro:   IPR011096 [H]

Pfam domain/function: PF07504 FTP; PF03413 PepSY; PF04389 Peptidase_M28; PF01447 Peptidase_M4; PF02868 Peptidase_M4_C; PF05547 Peptidase_M6 [H]

EC number: NA

Molecular weight: Translated: 48427; Mature: 48427

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAGCSSAGPGLPTAAPDLGHGLAKKVTADAMMAHLRALQNIANTNGGNRADGTPGFQA
CEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
SVDYVAKALRDKGFDVQTPQFDRLYPVSPGKPTLTVAGRGYPVDQASMLVQTPPGGLTGP
HHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCEEEECCCCCCCCCCCEEEECCCCCCCCC
AVRPAQPSGCAASDYPGALPKGAIAVVDDTRCSVVDKQNSAVARGASALIVVSAPDGHGA
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCHHHCCCEEEEEEECCCCCCC
PPTLFTPGYYKQLSVPVAVVNPSGAAALAGAGGPVRLILDAVNVKVTSRNVVAQTKTGSA
CCCEECCCCHHEEECCEEEECCCCCEEEECCCCCEEEEEEEEEEEEECCEEEEECCCCCC
HEVVMVGAHLDGSRAGPGINDNGSGVAAVLETALQLGPLAPVSNAVRFVFWGAGEDGLGG
CEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHH
VMDYLFGLDRDQLNDIALYLNFTMLGSPNAGFFTDDGDQSGPPAPGISAADVPEGSAGIE
HHHHHHCCCHHHHCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
RTLAGYLNLAGKRAADMPLNTRADYHPFMVAGVPIGGMTTGASQPKTTVQSRLWGGQAGV
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCC
PFDPNFQSPRDTADNINRDALAVMGSGVGFAVGSYAQSIGGVNGVPPHDKRHRTRVP
CCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLLAGCSSAGPGLPTAAPDLGHGLAKKVTADAMMAHLRALQNIANTNGGNRADGTPGFQA
CEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
SVDYVAKALRDKGFDVQTPQFDRLYPVSPGKPTLTVAGRGYPVDQASMLVQTPPGGLTGP
HHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCEEEECCCCCCCCCCCEEEECCCCCCCCC
AVRPAQPSGCAASDYPGALPKGAIAVVDDTRCSVVDKQNSAVARGASALIVVSAPDGHGA
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCHHHCCCEEEEEEECCCCCCC
PPTLFTPGYYKQLSVPVAVVNPSGAAALAGAGGPVRLILDAVNVKVTSRNVVAQTKTGSA
CCCEECCCCHHEEECCEEEECCCCCEEEECCCCCEEEEEEEEEEEEECCEEEEECCCCCC
HEVVMVGAHLDGSRAGPGINDNGSGVAAVLETALQLGPLAPVSNAVRFVFWGAGEDGLGG
CEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHH
VMDYLFGLDRDQLNDIALYLNFTMLGSPNAGFFTDDGDQSGPPAPGISAADVPEGSAGIE
HHHHHHCCCHHHHCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
RTLAGYLNLAGKRAADMPLNTRADYHPFMVAGVPIGGMTTGASQPKTTVQSRLWGGQAGV
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCC
PFDPNFQSPRDTADNINRDALAVMGSGVGFAVGSYAQSIGGVNGVPPHDKRHRTRVP
CCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA