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The map label for this gene is nrdB

Identifier: 41409770

GI number: 41409770

Start: 4080177

End: 4081112

Strand: Direct

Name: nrdB

Synonym: MAP3672

Alternate gene names: NA

Gene position: 4080177-4081112 (Clockwise)

Preceding gene: 41409769

Following gene: 41409772

Centisome position: 84.48

GC content: 66.56

Gene sequence:

>936_bases
ATGAACCGAACCCGAAGCGCCTCGATGGCGCAGGGGGGTCTCAACTGGGACAGCTTGCCGCTCAAGCTTTTTGCGGGCGG
CAACGCGAAATTCTGGAATCCTGCCGACATCGACTTCTCCCGTGACCGGGCCGACTGGGAACGGCTCACCGACGACGAAC
GCAGCTACGCCACCCGGCTGTGCGCTGAGTTCATCGCCGGTGAGGAATCGGTGACCCAGGACATCCAGCCGTTCATGGCC
GCGATGCGGGCCGAAGGCCGGCTCGGCGACGAGATGTATTTGACCCAGTTCGCCTTCGAGGAGGCCAAGCACGTCCAGGT
GTTCCGGATGTGGCTGGACGCCGTCGGTGTCACCGACGATCTGCACCACTTTCTCGACGACGTCCCCAGCTACCGGACGA
TCTTCTACGAGGAGCTGCCGGACTGCCTGAACGCGCTGACGATCGATCCGTCGCCGGCCGCCCAGGTGCGGGCGTCGGTG
ACCTACAACCACATGGTCGAAGGCATGCTGGCGCTGACCGGATACTTCGGCTGGCACAAGATCTGCGTGGAACGCGGCAT
CCTGCCCGGCATGCAGGAACTGGTGCGGCGCATCGGCGACGACGAGCGCCGGCACATGGCGTGGGGCACCTTCACCTGCC
GCCGGCACGTCGCCGCCGACGACGCCAACTGGGGCGTCTTCGAAACCCGGATGAACGAACTGATGCCGCTCGGGCTGCGC
CTGATCGAAGAGGGCTTCGCGCTCTACGACCCGATGCCCTTCGACCTGTCGGTGGACGAGTTCATGGCGTACGCCAGCGA
CAAGGGCATGCGGCGCTTCGGCACCATCGCCAGCGCCCGGGGCCGCCCGCTGGCCGAGATCGACCTGGACTACACGCCCG
TGCAGCTCGAGGACACCTTCGCCGACGAGGACGCCCGCGCGCTGGCCGCGGTGTGA

Upstream 100 bases:

>100_bases
AGCAGCCCGCGCTGGCGGTGCGCCGGCTGGTCGCGGTGCTGGCCGCCGCGTTCTCGCCCGCGCCGGCCCACTTTGCCACC
CCACGATCCGAGGAGGTCAC

Downstream 100 bases:

>100_bases
CGGCGAGCAGACGCAAAAGCCCCCAATGTCACGGCGGGTCGGGGGATTTCACGTCTGCTCGGCGGGTCACTCGACCTTCG
AGCCGCCGCCGGCGTCGCCG

Product: ribonucleotide-diphosphate reductase subunit beta

Products: ribonucleoside diphosphate; thioredoxin

Alternate protein names: Ribonucleotide reductase R2 subunit homolog; Ribonucleotide reductase small subunit homolog [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNRTRSASMAQGGLNWDSLPLKLFAGGNAKFWNPADIDFSRDRADWERLTDDERSYATRLCAEFIAGEESVTQDIQPFMA
AMRAEGRLGDEMYLTQFAFEEAKHVQVFRMWLDAVGVTDDLHHFLDDVPSYRTIFYEELPDCLNALTIDPSPAAQVRASV
TYNHMVEGMLALTGYFGWHKICVERGILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWGVFETRMNELMPLGLR
LIEEGFALYDPMPFDLSVDEFMAYASDKGMRRFGTIASARGRPLAEIDLDYTPVQLEDTFADEDARALAAV

Sequences:

>Translated_311_residues
MNRTRSASMAQGGLNWDSLPLKLFAGGNAKFWNPADIDFSRDRADWERLTDDERSYATRLCAEFIAGEESVTQDIQPFMA
AMRAEGRLGDEMYLTQFAFEEAKHVQVFRMWLDAVGVTDDLHHFLDDVPSYRTIFYEELPDCLNALTIDPSPAAQVRASV
TYNHMVEGMLALTGYFGWHKICVERGILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWGVFETRMNELMPLGLR
LIEEGFALYDPMPFDLSVDEFMAYASDKGMRRFGTIASARGRPLAEIDLDYTPVQLEDTFADEDARALAAV
>Mature_311_residues
MNRTRSASMAQGGLNWDSLPLKLFAGGNAKFWNPADIDFSRDRADWERLTDDERSYATRLCAEFIAGEESVTQDIQPFMA
AMRAEGRLGDEMYLTQFAFEEAKHVQVFRMWLDAVGVTDDLHHFLDDVPSYRTIFYEELPDCLNALTIDPSPAAQVRASV
TYNHMVEGMLALTGYFGWHKICVERGILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWGVFETRMNELMPLGLR
LIEEGFALYDPMPFDLSVDEFMAYASDKGMRRFGTIASARGRPLAEIDLDYTPVQLEDTFADEDARALAAV

Specific function: Probable oxidase that might be involved in lipid metabolism [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: 1.17.4.1

Molecular weight: Translated: 35337; Mature: 35337

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTRSASMAQGGLNWDSLPLKLFAGGNAKFWNPADIDFSRDRADWERLTDDERSYATRL
CCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHH
CAEFIAGEESVTQDIQPFMAAMRAEGRLGDEMYLTQFAFEEAKHVQVFRMWLDAVGVTDD
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LHHFLDDVPSYRTIFYEELPDCLNALTIDPSPAAQVRASVTYNHMVEGMLALTGYFGWHK
HHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ICVERGILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWGVFETRMNELMPLGLR
HHHHHCCCCCHHHHHHHHCCCHHHHEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LIEEGFALYDPMPFDLSVDEFMAYASDKGMRRFGTIASARGRPLAEIDLDYTPVQLEDTF
HHHCCHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCCEEEECCC
ADEDARALAAV
CCCHHHHHHCC
>Mature Secondary Structure
MNRTRSASMAQGGLNWDSLPLKLFAGGNAKFWNPADIDFSRDRADWERLTDDERSYATRL
CCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHH
CAEFIAGEESVTQDIQPFMAAMRAEGRLGDEMYLTQFAFEEAKHVQVFRMWLDAVGVTDD
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LHHFLDDVPSYRTIFYEELPDCLNALTIDPSPAAQVRASVTYNHMVEGMLALTGYFGWHK
HHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ICVERGILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWGVFETRMNELMPLGLR
HHHHHCCCCCHHHHHHHHCCCHHHHEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LIEEGFALYDPMPFDLSVDEFMAYASDKGMRRFGTIASARGRPLAEIDLDYTPVQLEDTF
HHHCCHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCCEEEECCC
ADEDARALAAV
CCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2'-deoxyribonucleoside diphosphate; thioredoxin disulfide; H2O

Specific reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA