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The map label for this gene is paaF [C]

Identifier: 41409748

GI number: 41409748

Start: 4053194

End: 4054156

Strand: Direct

Name: paaF [C]

Synonym: MAP3650

Alternate gene names: 41409748

Gene position: 4053194-4054156 (Clockwise)

Preceding gene: 41409747

Following gene: 41409750

Centisome position: 83.92

GC content: 73.1

Gene sequence:

>963_bases
ATGCTGCGGGTGGTCGACCTCTCCAGCGCGCCGCAGGACGGCCCCGCCTCACCGCCGGGTGTGATCGTCGCCGTCGGATC
GGCTGACCAGATTGCCCGGTCCGAATTCTGGCTCGAGGCAGCGACTTTCACCCTCACCGAAGACGCCTGCACGGACCGTC
GCGCCGTCACCGTCGATTCGGTGTCCACGTCGCTGGACGAGCTGACGGCACGCTGCCGGCGGTGGCCGCACGCCAGCGCG
ATCTGCGACGACGTGTTGCGCGCGGTGGATCCCACGGCGCCGGCGGCGCGGGGGCTGGTGACTGAGTCGCTGGCGTATTC
GACGCTGCAGGCCGGCCCGGAGTTCGTGCGCTGGCTCGACGAGCGCGGCCCGGCCCGCATGCCCGAGATCGCCGACCCGG
TGCTCGCTCGGCGCGACGGCGACGTGCTGCGGATCGCGTTCAACCGGCCGCAACGGCACAACGCGTTCTCCACCGATGCG
CGCGCCGCGCTGCTGGAGGCGCTGGCGGTTGCCCAGCTCGACCCGTCGGTGACCGGAATCGTGTTGAGCGGCAACGGCCC
CTCCTTTTGCAGCGGTGGGGATCTCGCCGAATTCGGCACCTTCGCCGATCCGGCCAGCGCGCACCTGGCGCGCACCCGGC
ACAGCCCCGCGCTGGTGCTCGACGCGCTGACCGCCCGGTTCGGCCGGGCGTGCCGCGCCGAGGTGCACGGCCGGGTGCTG
GGCAGCGGACTGGAGATGTCGGCGTTCTGCGGGTGGGTCAGCGCCCGGGACGACGCGGTGTTCGGGCTGCCCGAGTTGGC
GCTGGGGCTGATCCCCGGCGCCGGCGGCACCGTCAGCATCACCCGGCGGATCGGGCGTTGGCGCACGGCGTATCTCGTGC
TGTCGGGCCGCACGGTCGGCGCCGCGACCGCGTTGTCCTGGGGGCTGGTGGACGAGGTGGAAGCGGCAACGGCCTCGTCG
TAA

Upstream 100 bases:

>100_bases
CAAGTGTCCGCGAGCGATCGCATTCGAGGAGCAGCTGCCGCGCACCGACACTGGCAAGCTCTTCAAGAACGGGCTGATCG
AGAAGTATTCGGTGTGACCG

Downstream 100 bases:

>100_bases
TCCGTTGTGTCACTGTGGCTTGGAGTGGCCACAGGGCGGCGGTTTTTGTCGGTCCCGTTCCTACACTTACGCGAGGACGA
CGACCCCGTTTGACGTCGGA

Product: hypothetical protein

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MLRVVDLSSAPQDGPASPPGVIVAVGSADQIARSEFWLEAATFTLTEDACTDRRAVTVDSVSTSLDELTARCRRWPHASA
ICDDVLRAVDPTAPAARGLVTESLAYSTLQAGPEFVRWLDERGPARMPEIADPVLARRDGDVLRIAFNRPQRHNAFSTDA
RAALLEALAVAQLDPSVTGIVLSGNGPSFCSGGDLAEFGTFADPASAHLARTRHSPALVLDALTARFGRACRAEVHGRVL
GSGLEMSAFCGWVSARDDAVFGLPELALGLIPGAGGTVSITRRIGRWRTAYLVLSGRTVGAATALSWGLVDEVEAATASS

Sequences:

>Translated_320_residues
MLRVVDLSSAPQDGPASPPGVIVAVGSADQIARSEFWLEAATFTLTEDACTDRRAVTVDSVSTSLDELTARCRRWPHASA
ICDDVLRAVDPTAPAARGLVTESLAYSTLQAGPEFVRWLDERGPARMPEIADPVLARRDGDVLRIAFNRPQRHNAFSTDA
RAALLEALAVAQLDPSVTGIVLSGNGPSFCSGGDLAEFGTFADPASAHLARTRHSPALVLDALTARFGRACRAEVHGRVL
GSGLEMSAFCGWVSARDDAVFGLPELALGLIPGAGGTVSITRRIGRWRTAYLVLSGRTVGAATALSWGLVDEVEAATASS
>Mature_320_residues
MLRVVDLSSAPQDGPASPPGVIVAVGSADQIARSEFWLEAATFTLTEDACTDRRAVTVDSVSTSLDELTARCRRWPHASA
ICDDVLRAVDPTAPAARGLVTESLAYSTLQAGPEFVRWLDERGPARMPEIADPVLARRDGDVLRIAFNRPQRHNAFSTDA
RAALLEALAVAQLDPSVTGIVLSGNGPSFCSGGDLAEFGTFADPASAHLARTRHSPALVLDALTARFGRACRAEVHGRVL
GSGLEMSAFCGWVSARDDAVFGLPELALGLIPGAGGTVSITRRIGRWRTAYLVLSGRTVGAATALSWGLVDEVEAATASS

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=178, Percent_Identity=33.1460674157303, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI68989263, Length=160, Percent_Identity=33.125, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787659, Length=180, Percent_Identity=35.5555555555556, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1790281, Length=175, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788597, Length=176, Percent_Identity=29.5454545454545, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788682, Length=144, Percent_Identity=34.7222222222222, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI221142681, Length=179, Percent_Identity=28.4916201117318, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787660, Length=192, Percent_Identity=29.1666666666667, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17535521, Length=188, Percent_Identity=27.6595744680851, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17554946, Length=189, Percent_Identity=30.1587301587302, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25145438, Length=178, Percent_Identity=31.4606741573034, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=183, Percent_Identity=28.9617486338798, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17558304, Length=181, Percent_Identity=29.8342541436464, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=186, Percent_Identity=29.0322580645161, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI20129971, Length=177, Percent_Identity=33.8983050847458, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24653477, Length=177, Percent_Identity=33.8983050847458, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357171, Length=180, Percent_Identity=28.3333333333333, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653139, Length=170, Percent_Identity=30, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24650670, Length=185, Percent_Identity=29.1891891891892, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 33646; Mature: 33646

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRVVDLSSAPQDGPASPPGVIVAVGSADQIARSEFWLEAATFTLTEDACTDRRAVTVDS
CEEEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHEEEEEEHHHCCCCCEEEEHH
VSTSLDELTARCRRWPHASAICDDVLRAVDPTAPAARGLVTESLAYSTLQAGPEFVRWLD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
ERGPARMPEIADPVLARRDGDVLRIAFNRPQRHNAFSTDARAALLEALAVAQLDPSVTGI
HCCCCCCCHHHCHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
VLSGNGPSFCSGGDLAEFGTFADPASAHLARTRHSPALVLDALTARFGRACRAEVHGRVL
EEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GSGLEMSAFCGWVSARDDAVFGLPELALGLIPGAGGTVSITRRIGRWRTAYLVLSGRTVG
CCCCCHHHHHHHHCCCCCCEECCHHHHHHHCCCCCCEEHHHHHHCCEEEEEEEEECCCCC
AATALSWGLVDEVEAATASS
HHHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure
MLRVVDLSSAPQDGPASPPGVIVAVGSADQIARSEFWLEAATFTLTEDACTDRRAVTVDS
CEEEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHEEEEEEHHHCCCCCEEEEHH
VSTSLDELTARCRRWPHASAICDDVLRAVDPTAPAARGLVTESLAYSTLQAGPEFVRWLD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
ERGPARMPEIADPVLARRDGDVLRIAFNRPQRHNAFSTDARAALLEALAVAQLDPSVTGI
HCCCCCCCHHHCHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
VLSGNGPSFCSGGDLAEFGTFADPASAHLARTRHSPALVLDALTARFGRACRAEVHGRVL
EEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GSGLEMSAFCGWVSARDDAVFGLPELALGLIPGAGGTVSITRRIGRWRTAYLVLSGRTVG
CCCCCHHHHHHHHCCCCCCEECCHHHHHHHCCCCCCEEHHHHHHCCEEEEEEEEECCCCC
AATALSWGLVDEVEAATASS
HHHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA