Click here to switch to the map view.

The map label for this gene is desA3_2

Identifier: 41409644

GI number: 41409644

Start: 3947859

End: 3948959

Strand: Direct

Name: desA3_2

Synonym: MAP3546

Alternate gene names: 41409644

Gene position: 3947859-3948959 (Clockwise)

Preceding gene: 41409643

Following gene: 41409647

Centisome position: 81.74

GC content: 65.49

Gene sequence:

>1101_bases
GTGACACACAACAAGATAACCCTGACCCCCGAACAGGCCGAGGAATTCGGCCGTGAGCTCGACGCCCTCAAGGAACGGGT
GATGGCCGACCTCGGCGAAAAGGATGCCGACTACATTCGCCGCGTCATCAAGGCGCAGCGCGCGCTGGAAGTCGGTGGCC
GCGCCCTGCTCTTCCTGCCCCCGGCATGGCTGCTGGGCACCACCATGCTGGGCCTGTCGAAGATATTGGACAACATGGAG
ATCGGCCACAACGTCATGCACGGCCAGTACGACTGGATGCGCGACCCGGCGATCAGCGGCCGGTCCTTTGAATGGGACAC
CGCGTGCCCGGCCGACCAGTGGCGGCACTCGCACAACTACATGCACCACACCCACACCAACATCGTCGGCATGGACCGCG
ACATCGGGTACGGGATCCTGCGGATGAGCGAAGACCAGCCGTGGCAGCCGTATTTCCTCGGCAACCCGCTCTACGCGTTC
CTGCTGATGGTGCTGTTCCAGTACGGGGTGGCGCTGCACGAGCTGGAAACCGAACGCATCCGCTCCGGAGAGATCCGGCT
GGCGGACAAGCGCGAGGTGCTGCGCGAAATCTGGCAGAAGACCCGCCGCCAGACGCTCAAGGACTATGTCGCGTTCCCGC
TGCTGGCCGGGCCCTTCGCGCCGTTCGTGTTCACCGGCAACCTCGCCGCCAACCTGATCCGCAACGTGTGGTCGTACATG
ATCATCTTCTGCGGCCACTTCCCGGACGGCACACAGGAATTCACCGTCGAAGAGACGCAGGACGAGTCGCGCGGCATGTG
GTACTTCCGCCAGATCCTCGGCTCGGCAAACCTGACCGGCGGCAAGCTGTTTCATCTACTCTCCGGCAACCTGTCGCACC
AGATCGAGCACCACCTGTTCCCCGACATGCCGGCCCGGCGCTACGCCGAGATCGCGCCGGAGGTACAGGCGATCTGCCAA
CGCTACGGCGTCGCGTACAACCGCGGGCCGCTGCTGCGCCAGTTCGGCACCGTCGTGCGCAAGATCGTCAAGCTGTCGTT
CCCGGACGCGTGGGTCCCCGGCGCCGCCAAGCCCGCCGACCGCGAGCCGGTGGCCGCCTGA

Upstream 100 bases:

>100_bases
GGTCACCGGTGCGGTCTCGACCGCTCCCGATGAGGACGTGCAGATCTGCGTGTCCGTTCCGGTCGGTGACGTGGACCTGT
CCCTCTGAGGAGGAAAAACC

Downstream 100 bases:

>100_bases
GCGACTCCCGAGCGTGGGGGCCATGTACGGATTGCGGACGCCTCGCCTACACAGCCCCCACGCTCGGCGCAACGGGATGG
CTCAGCGCACCGCCGTCGGG

Product: DesA3_2

Products: NA

Alternate protein names: Delta(9)-desaturase; Stearoyl-CoA desaturase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MTHNKITLTPEQAEEFGRELDALKERVMADLGEKDADYIRRVIKAQRALEVGGRALLFLPPAWLLGTTMLGLSKILDNME
IGHNVMHGQYDWMRDPAISGRSFEWDTACPADQWRHSHNYMHHTHTNIVGMDRDIGYGILRMSEDQPWQPYFLGNPLYAF
LLMVLFQYGVALHELETERIRSGEIRLADKREVLREIWQKTRRQTLKDYVAFPLLAGPFAPFVFTGNLAANLIRNVWSYM
IIFCGHFPDGTQEFTVEETQDESRGMWYFRQILGSANLTGGKLFHLLSGNLSHQIEHHLFPDMPARRYAEIAPEVQAICQ
RYGVAYNRGPLLRQFGTVVRKIVKLSFPDAWVPGAAKPADREPVAA

Sequences:

>Translated_366_residues
MTHNKITLTPEQAEEFGRELDALKERVMADLGEKDADYIRRVIKAQRALEVGGRALLFLPPAWLLGTTMLGLSKILDNME
IGHNVMHGQYDWMRDPAISGRSFEWDTACPADQWRHSHNYMHHTHTNIVGMDRDIGYGILRMSEDQPWQPYFLGNPLYAF
LLMVLFQYGVALHELETERIRSGEIRLADKREVLREIWQKTRRQTLKDYVAFPLLAGPFAPFVFTGNLAANLIRNVWSYM
IIFCGHFPDGTQEFTVEETQDESRGMWYFRQILGSANLTGGKLFHLLSGNLSHQIEHHLFPDMPARRYAEIAPEVQAICQ
RYGVAYNRGPLLRQFGTVVRKIVKLSFPDAWVPGAAKPADREPVAA
>Mature_365_residues
THNKITLTPEQAEEFGRELDALKERVMADLGEKDADYIRRVIKAQRALEVGGRALLFLPPAWLLGTTMLGLSKILDNMEI
GHNVMHGQYDWMRDPAISGRSFEWDTACPADQWRHSHNYMHHTHTNIVGMDRDIGYGILRMSEDQPWQPYFLGNPLYAFL
LMVLFQYGVALHELETERIRSGEIRLADKREVLREIWQKTRRQTLKDYVAFPLLAGPFAPFVFTGNLAANLIRNVWSYMI
IFCGHFPDGTQEFTVEETQDESRGMWYFRQILGSANLTGGKLFHLLSGNLSHQIEHHLFPDMPARRYAEIAPEVQAICQR
YGVAYNRGPLLRQFGTVVRKIVKLSFPDAWVPGAAKPADREPVAA

Specific function: Desaturates stearoyl-CoA to form oleoyl-CoA [H]

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Probable). Note=Has been shown to be membrane-associated but no reliable trans-membrane regions are predicted by bioinformatics tools [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Homo sapiens, GI4758334, Length=257, Percent_Identity=25.2918287937743, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI214831730, Length=83, Percent_Identity=37.3493975903614, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI13375616, Length=138, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: NA

Molecular weight: Translated: 41970; Mature: 41839

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHNKITLTPEQAEEFGRELDALKERVMADLGEKDADYIRRVIKAQRALEVGGRALLFLP
CCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEC
PAWLLGTTMLGLSKILDNMEIGHNVMHGQYDWMRDPAISGRSFEWDTACPADQWRHSHNY
CHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHCCC
MHHTHTNIVGMDRDIGYGILRMSEDQPWQPYFLGNPLYAFLLMVLFQYGVALHELETERI
CEECCCCEEECCCCCCCCEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
RSGEIRLADKREVLREIWQKTRRQTLKDYVAFPLLAGPFAPFVFTGNLAANLIRNVWSYM
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHH
IIFCGHFPDGTQEFTVEETQDESRGMWYFRQILGSANLTGGKLFHLLSGNLSHQIEHHLF
HHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCC
PDMPARRYAEIAPEVQAICQRYGVAYNRGPLLRQFGTVVRKIVKLSFPDAWVPGAAKPAD
CCCCHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
REPVAA
CCCCCC
>Mature Secondary Structure 
THNKITLTPEQAEEFGRELDALKERVMADLGEKDADYIRRVIKAQRALEVGGRALLFLP
CCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEC
PAWLLGTTMLGLSKILDNMEIGHNVMHGQYDWMRDPAISGRSFEWDTACPADQWRHSHNY
CHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHCCC
MHHTHTNIVGMDRDIGYGILRMSEDQPWQPYFLGNPLYAFLLMVLFQYGVALHELETERI
CEECCCCEEECCCCCCCCEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
RSGEIRLADKREVLREIWQKTRRQTLKDYVAFPLLAGPFAPFVFTGNLAANLIRNVWSYM
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHH
IIFCGHFPDGTQEFTVEETQDESRGMWYFRQILGSANLTGGKLFHLLSGNLSHQIEHHLF
HHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCC
PDMPARRYAEIAPEVQAICQRYGVAYNRGPLLRQFGTVVRKIVKLSFPDAWVPGAAKPAD
CCCCHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
REPVAA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]