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The map label for this gene is fadE1_3

Identifier: 41409637

GI number: 41409637

Start: 3941627

End: 3942976

Strand: Reverse

Name: fadE1_3

Synonym: MAP3539c

Alternate gene names: 41409637

Gene position: 3942976-3941627 (Counterclockwise)

Preceding gene: 41409638

Following gene: 41409635

Centisome position: 81.64

GC content: 66.52

Gene sequence:

>1350_bases
GTGGCTTCATCGACGAGTCCGGCGCGGCGCGGCGCCGGGGAATGGTTGGCCACGGTGTGGGACTTCGAGACTGACCCCGA
ATACCAGGCGAAGCTGGATTGGGTCGAGAAATTCATGGCCGAAGAGCTGGAGCCGCTCGACCTGGTGGCCCTGGATCCCT
ACGACAAGAAGAACGCCGAGATGATGGCCATCCTGCGGCCGTTACAGCAGCAGGTGAAGGACCAGGGCCTGTGGGCCGCC
CACCTGCGACCGGAATTGGGCGGCCAGGGCTTCGGTCAGGTCAAGCTGGCGCTGCTCAACGAAATCCTCGGACGCTCACG
CTGGGCCCCGTCGGTATTCGGTTGTCAAGCACCGGATTCCGGCAACGCCGAGATACTGGCGCTGTTCGGCACCGACGAAC
AGAAGGCCCGCTACCTGCAGCCGCTGCTGGACGGCGAGATCACCTCCTGCTATTCGATGACCGAGCCGCAGGGTGGTTCG
GATCCCGGGCAATTCGTCACCGCGGCCACCCGCGACGGCGACTACTGGGTGATCAACGGCGAGAAGTGGTTCTCCACCAA
CGCCAAACACGCGTCGTTCTTCATCGTCATGGCGGTCACCAACCCGGAGGCCCGCACCTACGACAAGATGTCGCTGTTCA
TTGTTCCGGCCGAGACACCGGGCATCGAGATCGTGCGCAACGTCGGGGTGGGGGCCGAGTCCTCCAGCCGGGCCAGCCAC
GGCTACGTCCGCTACACCGACGTCCGGGTGCCCGCCGACCACGTGCTGGGCGGCGAGGGGCAGGCGTTCATGATCGCCCA
GACCCGGCTGGGCGGTGGCCGGATTCACCACGCGATGCGCACGATCGCCTTGGCGCGCAGCGCCTTTGACATGATGTGCG
AACGGGCGGTGTCCCGCAAGACCCGGCACGGGCGGCTGGCCGATTTCCAGATGACCCAGGAGAAGATCGCCGACAGCTGG
ATCCAGATCGAGCAGTTCCGCTTGCTGGTGTTGCGCACCGCGTGGTTGATCGACAAGCACCACGACTACCAGAAGGTGCG
CCGCGACATCGCGGCGGTGAAAGTGGCCATGCCGCAGGTGCTGCACGACGTCGCCCAACGGGCCCTGCACCTGCACGGCG
CGCTCGGCGTCTCCGACGAGATGCCGTTCGTCAAGATGCTGGTGGCCGCCGAGTCGCTGGGCATCGCCGACGGCGCCACC
GAGCTGCACAAGATGACGGTGGCCCGCCGCACGCTGCGCGAATACGAGCCCGTGTCAACGCCTTTCCCGTCGGCGCACAT
TCCGACCCGGCGGGCCGAGGCCCAGGCGCGGTTGGCCGAACGCCTGGAACACGCCGTCGCGGAATTTTAG

Upstream 100 bases:

>100_bases
CCAGGTGAAACTGGTCGAGATCGCTCAGCAGATCATCGACACCCGCGGTCAGGGCGCCTAGTCCTGCTCACCGCCGGTGG
CGCCGTCGCTCTAGGATGGG

Downstream 100 bases:

>100_bases
GGTTCTCGCCCGGCGTCGACTTAGTCTCGCCGACAAGCGGTTTCGGACCCAAATGAGTCGACGGCCGGCGATGGTCAGGA
GATGTAGCGGACGATGCTTT

Product: FadE1_3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MASSTSPARRGAGEWLATVWDFETDPEYQAKLDWVEKFMAEELEPLDLVALDPYDKKNAEMMAILRPLQQQVKDQGLWAA
HLRPELGGQGFGQVKLALLNEILGRSRWAPSVFGCQAPDSGNAEILALFGTDEQKARYLQPLLDGEITSCYSMTEPQGGS
DPGQFVTAATRDGDYWVINGEKWFSTNAKHASFFIVMAVTNPEARTYDKMSLFIVPAETPGIEIVRNVGVGAESSSRASH
GYVRYTDVRVPADHVLGGEGQAFMIAQTRLGGGRIHHAMRTIALARSAFDMMCERAVSRKTRHGRLADFQMTQEKIADSW
IQIEQFRLLVLRTAWLIDKHHDYQKVRRDIAAVKVAMPQVLHDVAQRALHLHGALGVSDEMPFVKMLVAAESLGIADGAT
ELHKMTVARRTLREYEPVSTPFPSAHIPTRRAEAQARLAERLEHAVAEF

Sequences:

>Translated_449_residues
MASSTSPARRGAGEWLATVWDFETDPEYQAKLDWVEKFMAEELEPLDLVALDPYDKKNAEMMAILRPLQQQVKDQGLWAA
HLRPELGGQGFGQVKLALLNEILGRSRWAPSVFGCQAPDSGNAEILALFGTDEQKARYLQPLLDGEITSCYSMTEPQGGS
DPGQFVTAATRDGDYWVINGEKWFSTNAKHASFFIVMAVTNPEARTYDKMSLFIVPAETPGIEIVRNVGVGAESSSRASH
GYVRYTDVRVPADHVLGGEGQAFMIAQTRLGGGRIHHAMRTIALARSAFDMMCERAVSRKTRHGRLADFQMTQEKIADSW
IQIEQFRLLVLRTAWLIDKHHDYQKVRRDIAAVKVAMPQVLHDVAQRALHLHGALGVSDEMPFVKMLVAAESLGIADGAT
ELHKMTVARRTLREYEPVSTPFPSAHIPTRRAEAQARLAERLEHAVAEF
>Mature_448_residues
ASSTSPARRGAGEWLATVWDFETDPEYQAKLDWVEKFMAEELEPLDLVALDPYDKKNAEMMAILRPLQQQVKDQGLWAAH
LRPELGGQGFGQVKLALLNEILGRSRWAPSVFGCQAPDSGNAEILALFGTDEQKARYLQPLLDGEITSCYSMTEPQGGSD
PGQFVTAATRDGDYWVINGEKWFSTNAKHASFFIVMAVTNPEARTYDKMSLFIVPAETPGIEIVRNVGVGAESSSRASHG
YVRYTDVRVPADHVLGGEGQAFMIAQTRLGGGRIHHAMRTIALARSAFDMMCERAVSRKTRHGRLADFQMTQEKIADSWI
QIEQFRLLVLRTAWLIDKHHDYQKVRRDIAAVKVAMPQVLHDVAQRALHLHGALGVSDEMPFVKMLVAAESLGIADGATE
LHKMTVARRTLREYEPVSTPFPSAHIPTRRAEAQARLAERLEHAVAEF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI38505218, Length=396, Percent_Identity=36.8686868686869, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI211971008, Length=358, Percent_Identity=38.8268156424581, Blast_Score=241, Evalue=7e-64,
Organism=Homo sapiens, GI48976061, Length=358, Percent_Identity=38.8268156424581, Blast_Score=241, Evalue=8e-64,
Organism=Homo sapiens, GI4557233, Length=423, Percent_Identity=30.7328605200946, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI4501859, Length=395, Percent_Identity=28.8607594936709, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI187960098, Length=403, Percent_Identity=29.0322580645161, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI4557231, Length=403, Percent_Identity=29.0322580645161, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI21361497, Length=390, Percent_Identity=27.1794871794872, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI7656849, Length=399, Percent_Identity=25.31328320802, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=25, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI226958414, Length=343, Percent_Identity=24.7813411078717, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=25.78125, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=25.78125, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI4501857, Length=399, Percent_Identity=25.5639097744361, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4503943, Length=293, Percent_Identity=27.6450511945392, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7669494, Length=277, Percent_Identity=28.158844765343, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI87081958, Length=290, Percent_Identity=28.2758620689655, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786223, Length=348, Percent_Identity=24.1379310344828, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562446, Length=351, Percent_Identity=38.7464387464387, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17534899, Length=351, Percent_Identity=29.6296296296296, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17506239, Length=389, Percent_Identity=28.7917737789203, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17508101, Length=344, Percent_Identity=29.3604651162791, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17570075, Length=405, Percent_Identity=25.9259259259259, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17569725, Length=353, Percent_Identity=28.328611898017, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17538396, Length=383, Percent_Identity=25.3263707571802, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71985184, Length=381, Percent_Identity=25.9842519685039, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=384, Percent_Identity=25.5208333333333, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71985192, Length=285, Percent_Identity=28.4210526315789, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71990804, Length=232, Percent_Identity=31.8965517241379, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71982178, Length=282, Percent_Identity=28.0141843971631, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32563615, Length=189, Percent_Identity=32.2751322751323, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=289, Percent_Identity=26.2975778546713, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17505929, Length=346, Percent_Identity=23.121387283237, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551932, Length=293, Percent_Identity=23.8907849829352, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356377, Length=356, Percent_Identity=30.8988764044944, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24646207, Length=356, Percent_Identity=29.4943820224719, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24666513, Length=400, Percent_Identity=28.75, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24660351, Length=389, Percent_Identity=29.5629820051414, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI21355753, Length=401, Percent_Identity=26.4339152119701, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281363737, Length=344, Percent_Identity=24.1279069767442, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19920834, Length=292, Percent_Identity=27.0547945205479, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.21 [H]

Molecular weight: Translated: 49993; Mature: 49861

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSTSPARRGAGEWLATVWDFETDPEYQAKLDWVEKFMAEELEPLDLVALDPYDKKNAE
CCCCCCCHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
MMAILRPLQQQVKDQGLWAAHLRPELGGQGFGQVKLALLNEILGRSRWAPSVFGCQAPDS
HHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GNAEILALFGTDEQKARYLQPLLDGEITSCYSMTEPQGGSDPGQFVTAATRDGDYWVING
CCCEEEEEECCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEECC
EKWFSTNAKHASFFIVMAVTNPEARTYDKMSLFIVPAETPGIEIVRNVGVGAESSSRASH
CEEECCCCCCCEEEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCCCCCCCC
GYVRYTDVRVPADHVLGGEGQAFMIAQTRLGGGRIHHAMRTIALARSAFDMMCERAVSRK
CEEEEEEEECCHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRHGRLADFQMTQEKIADSWIQIEQFRLLVLRTAWLIDKHHDYQKVRRDIAAVKVAMPQV
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LHDVAQRALHLHGALGVSDEMPFVKMLVAAESLGIADGATELHKMTVARRTLREYEPVST
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCC
PFPSAHIPTRRAEAQARLAERLEHAVAEF
CCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASSTSPARRGAGEWLATVWDFETDPEYQAKLDWVEKFMAEELEPLDLVALDPYDKKNAE
CCCCCCHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
MMAILRPLQQQVKDQGLWAAHLRPELGGQGFGQVKLALLNEILGRSRWAPSVFGCQAPDS
HHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GNAEILALFGTDEQKARYLQPLLDGEITSCYSMTEPQGGSDPGQFVTAATRDGDYWVING
CCCEEEEEECCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEECC
EKWFSTNAKHASFFIVMAVTNPEARTYDKMSLFIVPAETPGIEIVRNVGVGAESSSRASH
CEEECCCCCCCEEEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCCCCCCCC
GYVRYTDVRVPADHVLGGEGQAFMIAQTRLGGGRIHHAMRTIALARSAFDMMCERAVSRK
CEEEEEEEECCHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRHGRLADFQMTQEKIADSWIQIEQFRLLVLRTAWLIDKHHDYQKVRRDIAAVKVAMPQV
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LHDVAQRALHLHGALGVSDEMPFVKMLVAAESLGIADGATELHKMTVARRTLREYEPVST
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCC
PFPSAHIPTRRAEAQARLAERLEHAVAEF
CCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629170; 12420174 [H]