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The map label for this gene is bpoC_1

Identifier: 41409635

GI number: 41409635

Start: 3940145

End: 3940981

Strand: Reverse

Name: bpoC_1

Synonym: MAP3537c

Alternate gene names: 41409635

Gene position: 3940981-3940145 (Counterclockwise)

Preceding gene: 41409637

Following gene: 41409632

Centisome position: 81.6

GC content: 69.65

Gene sequence:

>837_bases
ATGCCCGATGTGATCGCCCACCATGGACTTCTCAAGGACACCCGGCTGCATGTCGACGACACCGGCGGGCCCGGCAGACC
GGTGCTGCTCATGCACCCGTGGCCGCTGTCCGGCCAGTCGTGGTCGGCACAGGTCCCGGTGCTGCACGCCGCCGGCTATC
GGGTGGTCACCTACGACCGGCGCGGTTTCGGGCGCAGCGACAAGCCGCTCACCGGGTACAGCTACTCCCAGCTCACGCAG
GACCTGCACACCCTGGTCGAATCCCTCGACCTGCGCGACCTCACCCTGGTGGGCTCCTCGATGGGCGGCGGCGAGGTCGC
CCGCTACCTGTCGACCTACGGCCCCGAGCGGGTGCGCAGCGTGGTGTTCGCCTCCTCGGTGACGCCGTACCTGTTGCAGA
CCACCGACAATCCGGACGGGCCGCTGACCATGAAGGACGCGGCGCGGGCGACGGCGTCGTTCGTCAAGGACCAGGACGCC
TTCTACGACCATCAGATGACCGAGTTCTTCTCCGCCAACGGACAATTGCGGGTGAGCCGGGCGACCCGCGCCGAGGCGCT
CAGGCTATGCAAGCAGGCCGGCAAGGAGGCGTCGCTGGCCTGCATGGCCGCCTGGGCCAACACCGACTTCCGTCCCGACC
TGACCCGGGTGTCGGTGCCGGCGCTGATCATCCACGGCGAGGGCGACGAATCCGTGCCGCTCGCCGGGTCGGCGCGGCGC
ACCCACCGGGCGATACCGGGCAGCCGGCTGTGCGTGATCGCCGACGGGCCGCACGGTTGCCACATCAGCCACGCGCAAGA
GTTCAACGCGGCACTGCTGGACTTTCTGGCGGCCTAG

Upstream 100 bases:

>100_bases
TTTCGGCTGCCAACAATAGCGCCCGGCCACGGTTAGCCCCGGACGGTCACGGGTAGTAGCCGGTGAGCCAGCGAACTCCA
CCGCCGCGGAAGGTCGTTTC

Downstream 100 bases:

>100_bases
GTGCCTGGGTGCGCGGCGCCGTTTCGGACGAGCCGTCGCGGGAATCCCACCCGCAACGCTGACCGCAGGAAAGGAAGGCG
CATGCCAGACCACAAGGGCC

Product: BpoC_1

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: BPO2; Bromide peroxidase [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MPDVIAHHGLLKDTRLHVDDTGGPGRPVLLMHPWPLSGQSWSAQVPVLHAAGYRVVTYDRRGFGRSDKPLTGYSYSQLTQ
DLHTLVESLDLRDLTLVGSSMGGGEVARYLSTYGPERVRSVVFASSVTPYLLQTTDNPDGPLTMKDAARATASFVKDQDA
FYDHQMTEFFSANGQLRVSRATRAEALRLCKQAGKEASLACMAAWANTDFRPDLTRVSVPALIIHGEGDESVPLAGSARR
THRAIPGSRLCVIADGPHGCHISHAQEFNAALLDFLAA

Sequences:

>Translated_278_residues
MPDVIAHHGLLKDTRLHVDDTGGPGRPVLLMHPWPLSGQSWSAQVPVLHAAGYRVVTYDRRGFGRSDKPLTGYSYSQLTQ
DLHTLVESLDLRDLTLVGSSMGGGEVARYLSTYGPERVRSVVFASSVTPYLLQTTDNPDGPLTMKDAARATASFVKDQDA
FYDHQMTEFFSANGQLRVSRATRAEALRLCKQAGKEASLACMAAWANTDFRPDLTRVSVPALIIHGEGDESVPLAGSARR
THRAIPGSRLCVIADGPHGCHISHAQEFNAALLDFLAA
>Mature_277_residues
PDVIAHHGLLKDTRLHVDDTGGPGRPVLLMHPWPLSGQSWSAQVPVLHAAGYRVVTYDRRGFGRSDKPLTGYSYSQLTQD
LHTLVESLDLRDLTLVGSSMGGGEVARYLSTYGPERVRSVVFASSVTPYLLQTTDNPDGPLTMKDAARATASFVKDQDAF
YDHQMTEFFSANGQLRVSRATRAEALRLCKQAGKEASLACMAAWANTDFRPDLTRVSVPALIIHGEGDESVPLAGSARRT
HRAIPGSRLCVIADGPHGCHISHAQEFNAALLDFLAA

Specific function: May be a chlorinating enzyme involved in 7- chlorotetracycline biosynthesis [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial non-heme bromo- and chloro- peroxidases family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=300, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 30164; Mature: 30033

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDVIAHHGLLKDTRLHVDDTGGPGRPVLLMHPWPLSGQSWSAQVPVLHAAGYRVVTYDR
CCCCHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCEEEEEECC
RGFGRSDKPLTGYSYSQLTQDLHTLVESLDLRDLTLVGSSMGGGEVARYLSTYGPERVRS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCHHHHHH
VVFASSVTPYLLQTTDNPDGPLTMKDAARATASFVKDQDAFYDHQMTEFFSANGQLRVSR
HHHHCCCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEH
ATRAEALRLCKQAGKEASLACMAAWANTDFRPDLTRVSVPALIIHGEGDESVPLAGSARR
HHHHHHHHHHHHCCCCHHEEEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCHH
THRAIPGSRLCVIADGPHGCHISHAQEFNAALLDFLAA
HHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PDVIAHHGLLKDTRLHVDDTGGPGRPVLLMHPWPLSGQSWSAQVPVLHAAGYRVVTYDR
CCCHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCEEEEEECC
RGFGRSDKPLTGYSYSQLTQDLHTLVESLDLRDLTLVGSSMGGGEVARYLSTYGPERVRS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCHHHHHH
VVFASSVTPYLLQTTDNPDGPLTMKDAARATASFVKDQDAFYDHQMTEFFSANGQLRVSR
HHHHCCCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEH
ATRAEALRLCKQAGKEASLACMAAWANTDFRPDLTRVSVPALIIHGEGDESVPLAGSARR
HHHHHHHHHHHHCCCCHHEEEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCHH
THRAIPGSRLCVIADGPHGCHISHAQEFNAALLDFLAA
HHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1527491; 1783900; 7664081; 9642069 [H]