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The map label for this gene is cdd

Identifier: 41409538

GI number: 41409538

Start: 3820268

End: 3820669

Strand: Reverse

Name: cdd

Synonym: MAP3440c

Alternate gene names: 41409538

Gene position: 3820669-3820268 (Counterclockwise)

Preceding gene: 41409544

Following gene: 41409537

Centisome position: 79.11

GC content: 72.89

Gene sequence:

>402_bases
ATGCCGGACATTGACTGGAATGCACTGCGGGACAAGGCAATCGACGTGTCCGCGGGCGCCTATGCGCCGTACTCGCGGTT
CCGGGTGGGCGCGGCCGGGCTGGTCGACGACGGGCGGGTGGTGACCGGTTGCAATGTGGAGAACATCTCATATGGCCTTG
GTCTCTGCGCCGAGTGCGCGGTGGTGTGCGCCCTGTATGCGAGCGGCGGCGGCCGGCTGGTCGCGCTGGCGTGCGTGGAC
GGGCGCGGATCGGTGCTGACGCCGTGCGGGCGGTGCCGCCAGGTGCTGGCCGAACACGGCGGCCCGGAGCTGCTGATCGA
CCATCCGGGCGGGCCGCGCCGGCTCGGCGAGCTGCTGCCGGACGCGTTCGGCCCCGACCAGCTGGCCGCCGGGCGGGACT
GA

Upstream 100 bases:

>100_bases
CTCGCACGCGGCGCGCCCCGCGCCGATGTCCGTCAAGCGAAATGCCGCTTTCCGGCTAGGGTGACTGTCGGTACAGGCCG
TGGCTGAGCGGGGTTTCGTT

Downstream 100 bases:

>100_bases
TGCGGCCCGGGTTCGACGCGCCCACGGTGATTAGGACCAAGCGCGACGGCGGCCGGCTGTCCGACGCCGCCATCGACTGG
GTGATCGACGCCTACACCGG

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MPDIDWNALRDKAIDVSAGAYAPYSRFRVGAAGLVDDGRVVTGCNVENISYGLGLCAECAVVCALYASGGGRLVALACVD
GRGSVLTPCGRCRQVLAEHGGPELLIDHPGGPRRLGELLPDAFGPDQLAAGRD

Sequences:

>Translated_133_residues
MPDIDWNALRDKAIDVSAGAYAPYSRFRVGAAGLVDDGRVVTGCNVENISYGLGLCAECAVVCALYASGGGRLVALACVD
GRGSVLTPCGRCRQVLAEHGGPELLIDHPGGPRRLGELLPDAFGPDQLAAGRD
>Mature_132_residues
PDIDWNALRDKAIDVSAGAYAPYSRFRVGAAGLVDDGRVVTGCNVENISYGLGLCAECAVVCALYASGGGRLVALACVDG
RGSVLTPCGRCRQVLAEHGGPELLIDHPGGPRRLGELLPDAFGPDQLAAGRD

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=123, Percent_Identity=38.2113821138211, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17540514, Length=113, Percent_Identity=39.8230088495575, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17551074, Length=124, Percent_Identity=37.0967741935484, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323274, Length=136, Percent_Identity=34.5588235294118, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19920920, Length=106, Percent_Identity=37.7358490566038, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582741, Length=122, Percent_Identity=34.4262295081967, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24582744, Length=98, Percent_Identity=39.7959183673469, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 13739; Mature: 13608

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDIDWNALRDKAIDVSAGAYAPYSRFRVGAAGLVDDGRVVTGCNVENISYGLGLCAECA
CCCCCCCHHHCCCEECCCCCCCCHHHEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHH
VVCALYASGGGRLVALACVDGRGSVLTPCGRCRQVLAEHGGPELLIDHPGGPRRLGELLP
HHHHHHCCCCCEEEEEEEECCCCCEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHCC
DAFGPDQLAAGRD
CCCCCCCCCCCCC
>Mature Secondary Structure 
PDIDWNALRDKAIDVSAGAYAPYSRFRVGAAGLVDDGRVVTGCNVENISYGLGLCAECA
CCCCCCHHHCCCEECCCCCCCCHHHEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHH
VVCALYASGGGRLVALACVDGRGSVLTPCGRCRQVLAEHGGPELLIDHPGGPRRLGELLP
HHHHHHCCCCCEEEEEEEECCCCCEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHCC
DAFGPDQLAAGRD
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]