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The map label for this gene is lrp [H]

Identifier: 41409509

GI number: 41409509

Start: 3785605

End: 3786057

Strand: Reverse

Name: lrp [H]

Synonym: MAP3411c

Alternate gene names: 41409509

Gene position: 3786057-3785605 (Counterclockwise)

Preceding gene: 41409515

Following gene: 41409508

Centisome position: 78.39

GC content: 66.89

Gene sequence:

>453_bases
ATGAGTGAGACGCTCGACGATGTCGACCGGATTCTGGTGCGCGAGCTGGTCGCCGACGGCCGCGCCACGCTGGCCGAGCT
GGCCGCCAGCGCCCGGTTGTCGGTCTCGGCGGTGCAGTCGCGGGTGCGCAGGCTGGAGGCCCGCGGCGTGATCACGGGAT
ACTCCGCGCGCATCGAACCGGAGGCGGTCGGGCACCGGCTGTCGGCGTTCGTGGCCATCACTCCTCTGGATCCCTCTCAA
CCCGATGATGCGCCGGCCCGCCTGCAGCACATCGAGGAGATCGAATCGTGCCACTCGGTGGCCGGCGAGGAAAGCTACGT
GCTGCTGGTGCGCGTCGAGTCCGCCCGGGCGCTCGAGGACCTGCTGCAGCGGATCCGGACCGCCGCGAACGTCAGGACGC
GAAGCACCATCATATTGAACACATTTTACGACAACAGGGTATATGTACCGTAA

Upstream 100 bases:

>100_bases
ACATCGCCGAGAGGCCCGCGGCGAACATCGCCCGCAACCGCCAGGTGGGCAACCATTTCGGCCGGCTCACCGGGCACCGC
CGCTGCGATAGTCTCCGGCC

Downstream 100 bases:

>100_bases
ATATTACTGCCTATACCTCATGATTTCGTAAAGATCGGCTACCATAGCCGCATGACCGCCGCACTGGAACGCCTGGCCCG
CGCCCGCTCCTGCACCGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MSETLDDVDRILVRELVADGRATLAELAASARLSVSAVQSRVRRLEARGVITGYSARIEPEAVGHRLSAFVAITPLDPSQ
PDDAPARLQHIEEIESCHSVAGEESYVLLVRVESARALEDLLQRIRTAANVRTRSTIILNTFYDNRVYVP

Sequences:

>Translated_150_residues
MSETLDDVDRILVRELVADGRATLAELAASARLSVSAVQSRVRRLEARGVITGYSARIEPEAVGHRLSAFVAITPLDPSQ
PDDAPARLQHIEEIESCHSVAGEESYVLLVRVESARALEDLLQRIRTAANVRTRSTIILNTFYDNRVYVP
>Mature_149_residues
SETLDDVDRILVRELVADGRATLAELAASARLSVSAVQSRVRRLEARGVITGYSARIEPEAVGHRLSAFVAITPLDPSQP
DDAPARLQHIEEIESCHSVAGEESYVLLVRVESARALEDLLQRIRTAANVRTRSTIILNTFYDNRVYVP

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=124, Percent_Identity=38.7096774193548, Blast_Score=78, Evalue=2e-16,
Organism=Escherichia coli, GI1790182, Length=136, Percent_Identity=25.7352941176471, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 16566; Mature: 16435

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETLDDVDRILVRELVADGRATLAELAASARLSVSAVQSRVRRLEARGVITGYSARIEP
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCH
EAVGHRLSAFVAITPLDPSQPDDAPARLQHIEEIESCHSVAGEESYVLLVRVESARALED
HHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHH
LLQRIRTAANVRTRSTIILNTFYDNRVYVP
HHHHHHHHHCCCCCCEEEEEEEECCEEECC
>Mature Secondary Structure 
SETLDDVDRILVRELVADGRATLAELAASARLSVSAVQSRVRRLEARGVITGYSARIEP
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCH
EAVGHRLSAFVAITPLDPSQPDDAPARLQHIEEIESCHSVAGEESYVLLVRVESARALED
HHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHH
LLQRIRTAANVRTRSTIILNTFYDNRVYVP
HHHHHHHHHCCCCCCEEEEEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]