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The map label for this gene is fadE25_4

Identifier: 41409490

GI number: 41409490

Start: 3768368

End: 3769537

Strand: Reverse

Name: fadE25_4

Synonym: MAP3392c

Alternate gene names: 41409490

Gene position: 3769537-3768368 (Counterclockwise)

Preceding gene: 41409491

Following gene: 41409489

Centisome position: 78.05

GC content: 68.55

Gene sequence:

>1170_bases
ATGGCTGGATGGGCCGGAAACCCCGACTTCGATCTGTTCCAACTGCCCGAGGAGCACCAGGAGCTGCGTGCCGCGATCCG
GGCGCTGGCGGAAAAGGAGATCGCTCCGCACGCCGCCGACGTGGACGAGAACTCCCGGTTCCCGCAGGAGGCGCTGGAGG
CGTTGAACGCGGCGGGGTTCAACGCCGTGCACGTGCCGGAGGAGTACGGCGGGCAGGGCGCCGACTCGGTGGCGGCCTGC
ATCGTCATCGAGGAGGTCGCCCGCGTCGACACCTCGGCGTCGCTGATCCCCGCGGTCAACAAGCTGGGCACCATGGGGCT
GATCCTGCGCGGCTCCGACGAGCTGAAGAAGCAGGTGCTGCCGTCGATCGCGGACGGCTCGGCGATGGCGTCCTACGCGC
TCTCCGAGCGCGAGGCCGGCAGCGACGCGGCGTCGATGCGCACCCGGGCCCGCGCCGACGGGGACGACTGGATCCTCAAC
GGCGCCAAGTGCTGGATCACCAACGGCGGCAAGTCGAGCTGGTACACGGTGATGGCCGTGACCGATCCGGACAAGGGCGC
CAACGGCATCTCGTCGTTCATGGTGCACAAGGACGACGAGGGTTTCACCGTCGGGCCCAAGGAGAAGAAGCTCGGCATCA
AGGGCTCGCCGACCACCGAGCTGTACTTCGAGAACTGCCGCATCCCGGGCGACCGGATCATCGGCGAGCCGGGCACCGGC
TTCAAGACCGCGCTGGCGACGCTGGACCACACCCGGCCCACCATCGGTGCCCAGGCCGTCGGGATCGCGCAGGGCGCGCT
GGACGCCGCCATCGCATACACCAAGGAGCGCAAGCAGTTCGGCCGACCGGTCAGCGACAACCAGGGTGTGCAGTTCATGC
TCGCCGACATGGCGATGAAGGTGGAGTCGGCCCGGCTGATGGTGTACCACGCCGCCGCCCGCGCCGAGCGCGGCGAATCG
CACCTGGGGTTCATCTCCGCGGCGTCGAAGTGCCTGGCGTCCGACGTCGCGATGGAGGTGACCACGGACGCGGTGCAGCT
GTTCGGCGGCTACGGGTACACGCAGGACTTCCCGGTCGAGCGGATGATGCGCGACGCCAAGATCACCCAGATCTACGAGG
GCACCAATCAGATTCAGCGGGTGGTGATGTCGCGGGCGCTGTTGCGCTGA

Upstream 100 bases:

>100_bases
GTTCCAGACCCAGCTGGCCGACAGCGTGCGGGCCAAGGATGAGGCGCTGCAAAGGCTGCACGGTAAAGTTACCGGTCAGT
AGCACTAGGAGGCGTTAGAG

Downstream 100 bases:

>100_bases
GCGTTGCGCGTGGCTGTTGGGAAAAGCCCAGCGGTACCGCATAGGATTTCCCCGGTGGGTGAAGTCCAGACCGACGGCCG
GTAAACAGGCACCGGCCACC

Product: FadE25_4

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MAGWAGNPDFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQEALEALNAAGFNAVHVPEEYGGQGADSVAAC
IVIEEVARVDTSASLIPAVNKLGTMGLILRGSDELKKQVLPSIADGSAMASYALSEREAGSDAASMRTRARADGDDWILN
GAKCWITNGGKSSWYTVMAVTDPDKGANGISSFMVHKDDEGFTVGPKEKKLGIKGSPTTELYFENCRIPGDRIIGEPGTG
FKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMAMKVESARLMVYHAAARAERGES
HLGFISAASKCLASDVAMEVTTDAVQLFGGYGYTQDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR

Sequences:

>Translated_389_residues
MAGWAGNPDFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQEALEALNAAGFNAVHVPEEYGGQGADSVAAC
IVIEEVARVDTSASLIPAVNKLGTMGLILRGSDELKKQVLPSIADGSAMASYALSEREAGSDAASMRTRARADGDDWILN
GAKCWITNGGKSSWYTVMAVTDPDKGANGISSFMVHKDDEGFTVGPKEKKLGIKGSPTTELYFENCRIPGDRIIGEPGTG
FKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMAMKVESARLMVYHAAARAERGES
HLGFISAASKCLASDVAMEVTTDAVQLFGGYGYTQDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR
>Mature_388_residues
AGWAGNPDFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQEALEALNAAGFNAVHVPEEYGGQGADSVAACI
VIEEVARVDTSASLIPAVNKLGTMGLILRGSDELKKQVLPSIADGSAMASYALSEREAGSDAASMRTRARADGDDWILNG
AKCWITNGGKSSWYTVMAVTDPDKGANGISSFMVHKDDEGFTVGPKEKKLGIKGSPTTELYFENCRIPGDRIIGEPGTGF
KTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMAMKVESARLMVYHAAARAERGESH
LGFISAASKCLASDVAMEVTTDAVQLFGGYGYTQDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=383, Percent_Identity=45.6919060052219, Blast_Score=318, Evalue=5e-87,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=40.9574468085106, Blast_Score=301, Evalue=5e-82,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=40.9574468085106, Blast_Score=301, Evalue=5e-82,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=38.563829787234, Blast_Score=279, Evalue=4e-75,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=34.1333333333333, Blast_Score=238, Evalue=7e-63,
Organism=Homo sapiens, GI21361497, Length=352, Percent_Identity=37.7840909090909, Blast_Score=235, Evalue=6e-62,
Organism=Homo sapiens, GI226958412, Length=379, Percent_Identity=34.3007915567282, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI4557235, Length=340, Percent_Identity=35.5882352941176, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI76496475, Length=340, Percent_Identity=35.5882352941176, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI226958414, Length=346, Percent_Identity=34.6820809248555, Blast_Score=207, Evalue=9e-54,
Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=32.010582010582, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI4503943, Length=391, Percent_Identity=24.2966751918159, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI7669494, Length=380, Percent_Identity=23.6842105263158, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI48976061, Length=295, Percent_Identity=26.7796610169492, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI211971008, Length=295, Percent_Identity=26.7796610169492, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI38505218, Length=297, Percent_Identity=23.2323232323232, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=31.758530183727, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1786223, Length=381, Percent_Identity=28.8713910761155, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI87082384, Length=319, Percent_Identity=23.1974921630094, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081702, Length=373, Percent_Identity=24.9329758713137, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=42.7440633245383, Blast_Score=318, Evalue=4e-87,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=38.5224274406332, Blast_Score=291, Evalue=5e-79,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=40.9703504043127, Blast_Score=288, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17534899, Length=381, Percent_Identity=38.3202099737533, Blast_Score=288, Evalue=5e-78,
Organism=Caenorhabditis elegans, GI17506239, Length=374, Percent_Identity=37.9679144385027, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17533517, Length=375, Percent_Identity=36.5333333333333, Blast_Score=257, Evalue=7e-69,
Organism=Caenorhabditis elegans, GI17538396, Length=387, Percent_Identity=36.6925064599483, Blast_Score=251, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI71985184, Length=383, Percent_Identity=34.7258485639687, Blast_Score=221, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI71990804, Length=297, Percent_Identity=39.7306397306397, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI32563615, Length=238, Percent_Identity=41.5966386554622, Blast_Score=191, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI71985192, Length=317, Percent_Identity=34.7003154574132, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17551932, Length=373, Percent_Identity=30.5630026809651, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71982178, Length=278, Percent_Identity=33.4532374100719, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17505929, Length=378, Percent_Identity=30.1587301587302, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17531909, Length=236, Percent_Identity=33.4745762711864, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17534353, Length=378, Percent_Identity=25.3968253968254, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17531913, Length=171, Percent_Identity=30.9941520467836, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI86563381, Length=323, Percent_Identity=26.9349845201238, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI86563383, Length=323, Percent_Identity=26.9349845201238, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562446, Length=336, Percent_Identity=25, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24660351, Length=384, Percent_Identity=39.84375, Blast_Score=298, Evalue=3e-81,
Organism=Drosophila melanogaster, GI21356377, Length=379, Percent_Identity=40.3693931398417, Blast_Score=284, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=39.1534391534392, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24666513, Length=374, Percent_Identity=35.8288770053476, Blast_Score=244, Evalue=9e-65,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=34.2036553524804, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI281363737, Length=355, Percent_Identity=35.4929577464789, Blast_Score=208, Evalue=6e-54,
Organism=Drosophila melanogaster, GI19920834, Length=380, Percent_Identity=28.4210526315789, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI45550141, Length=322, Percent_Identity=27.0186335403727, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221473076, Length=322, Percent_Identity=27.0186335403727, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41781; Mature: 41649

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGWAGNPDFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQEALEALNAAGF
CCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCC
NAVHVPEEYGGQGADSVAACIVIEEVARVDTSASLIPAVNKLGTMGLILRGSDELKKQVL
CEEECCHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHC
PSIADGSAMASYALSEREAGSDAASMRTRARADGDDWILNGAKCWITNGGKSSWYTVMAV
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCEEEEEECCCCCCEEEEEEE
TDPDKGANGISSFMVHKDDEGFTVGPKEKKLGIKGSPTTELYFENCRIPGDRIIGEPGTG
ECCCCCCCHHHHHEEEECCCCCEECCCHHCCCCCCCCCCEEEEECCCCCCCCEECCCCCC
FKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMAMK
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHH
VESARLMVYHAAARAERGESHLGFISAASKCLASDVAMEVTTDAVQLFGGYGYTQDFPVE
HHHHHEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
RMMRDAKITQIYEGTNQIQRVVMSRALLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGWAGNPDFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQEALEALNAAGF
CCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCC
NAVHVPEEYGGQGADSVAACIVIEEVARVDTSASLIPAVNKLGTMGLILRGSDELKKQVL
CEEECCHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHC
PSIADGSAMASYALSEREAGSDAASMRTRARADGDDWILNGAKCWITNGGKSSWYTVMAV
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCEEEEEECCCCCCEEEEEEE
TDPDKGANGISSFMVHKDDEGFTVGPKEKKLGIKGSPTTELYFENCRIPGDRIIGEPGTG
ECCCCCCCHHHHHEEEECCCCCEECCCHHCCCCCCCCCCEEEEECCCCCCCCEECCCCCC
FKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMAMK
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHH
VESARLMVYHAAARAERGESHLGFISAASKCLASDVAMEVTTDAVQLFGGYGYTQDFPVE
HHHHHEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
RMMRDAKITQIYEGTNQIQRVVMSRALLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]