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The map label for this gene is sigH

Identifier: 41409422

GI number: 41409422

Start: 3692929

End: 3693735

Strand: Reverse

Name: sigH

Synonym: MAP3324c

Alternate gene names: 41409422

Gene position: 3693735-3692929 (Counterclockwise)

Preceding gene: 41409424

Following gene: 41409421

Centisome position: 76.48

GC content: 63.69

Gene sequence:

>807_bases
GTGGTGTCAACGGCGACGAGCCTGTTAGGCGAGGAGCAGTTGGCTGGCTTCCTTGCGAGTCCGGGGGCGCTTTCGGTGCT
TTCCGGTGACACCGCAGCAGAAGGGACCGGGTTTATCGAAATGGCCGATTCTCCAGATGGCCCAGACGGCGTGACCAGCC
CGGAAGTCCCCGAAGCGCACGCAGAACCGGCGGCGCACGAAGAGGCCCGCGAAGAGACCGACGCCGAATTGACGGCGCGG
TTCGAGCGCGACGCGATTCCCCTGCTGGACCAGCTGTACGGCGGTGCGCTGCGGATGACGCGCAATCCGGCCGACGCCGA
GGATTTGCTGCAGGAAACGATGGTGAAGGCCTACGCGGGGTTCCGCTCGTTTCGCGCCGGCACCAATCTCAAGGCGTGGC
TCTACCGCATCCTGACCAACACCTACATCAACAGCTACCGCAAGAAGCAGCGCCAGCCCGCGGAGTATCCGACCGAGGAA
ATCACCGATTGGCAGCTGGCGTCGAATGCGGAGCATTCCTCGACCGGGCTGCGTTCGGCCGAGGTCGAGGCGCTGGAATC
GCTGCCGGATTCCGAAATCAAAGACGCGCTGCAGGCTTTGCCGGAAGAATTCCGGATGGCGGTGTATTACGCCGATGTCG
AGGGTTTTCCGTACAAGGAAATCGCCGAGATCATGGATACGCCGATTGGAACGGTAATGTCACGGCTGCACCGCGGCCGA
CGGCAGCTGCGTGGCCTGCTGGCCGACGTGGCCAAGGAGCGCGGTTTCAACCGCGGGCAGCAGACGCACGAGGAGGTGTC
GTCATGA

Upstream 100 bases:

>100_bases
CCAATCGGTCTTTGGATCGGTATTGGGATCGGTCTTTGGTGCGGTGGGCCACACCCGGGCAGACACTGTCGGGGGCAGCC
TTTAGATTGGGAGGAGCAGC

Downstream 100 bases:

>100_bases
GTGAGTCATCCGGGCAAGGCGACGCCTTGTCCGAATCCTGCCCGAACGACGATTCCCACGGCGCCGTCGGCTGCGCGGAG
GTGATCCGCCAGGTCTGGCT

Product: RNA polymerase sigma factor RpoE

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MVSTATSLLGEEQLAGFLASPGALSVLSGDTAAEGTGFIEMADSPDGPDGVTSPEVPEAHAEPAAHEEAREETDAELTAR
FERDAIPLLDQLYGGALRMTRNPADAEDLLQETMVKAYAGFRSFRAGTNLKAWLYRILTNTYINSYRKKQRQPAEYPTEE
ITDWQLASNAEHSSTGLRSAEVEALESLPDSEIKDALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGR
RQLRGLLADVAKERGFNRGQQTHEEVSS

Sequences:

>Translated_268_residues
MVSTATSLLGEEQLAGFLASPGALSVLSGDTAAEGTGFIEMADSPDGPDGVTSPEVPEAHAEPAAHEEAREETDAELTAR
FERDAIPLLDQLYGGALRMTRNPADAEDLLQETMVKAYAGFRSFRAGTNLKAWLYRILTNTYINSYRKKQRQPAEYPTEE
ITDWQLASNAEHSSTGLRSAEVEALESLPDSEIKDALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGR
RQLRGLLADVAKERGFNRGQQTHEEVSS
>Mature_268_residues
MVSTATSLLGEEQLAGFLASPGALSVLSGDTAAEGTGFIEMADSPDGPDGVTSPEVPEAHAEPAAHEEAREETDAELTAR
FERDAIPLLDQLYGGALRMTRNPADAEDLLQETMVKAYAGFRSFRAGTNLKAWLYRILTNTYINSYRKKQRQPAEYPTEE
ITDWQLASNAEHSSTGLRSAEVEALESLPDSEIKDALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGR
RQLRGLLADVAKERGFNRGQQTHEEVSS

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=141, Percent_Identity=36.8794326241135, Blast_Score=88, Evalue=6e-19,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014293
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 29499; Mature: 29499

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSTATSLLGEEQLAGFLASPGALSVLSGDTAAEGTGFIEMADSPDGPDGVTSPEVPEAH
CCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
AEPAAHEEAREETDAELTARFERDAIPLLDQLYGGALRMTRNPADAEDLLQETMVKAYAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHH
FRSFRAGTNLKAWLYRILTNTYINSYRKKQRQPAEYPTEEITDWQLASNAEHSSTGLRSA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHCCCCHHHCCCHHH
EVEALESLPDSEIKDALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHH
RQLRGLLADVAKERGFNRGQQTHEEVSS
HHHHHHHHHHHHHCCCCCCHHHHHHHCC
>Mature Secondary Structure
MVSTATSLLGEEQLAGFLASPGALSVLSGDTAAEGTGFIEMADSPDGPDGVTSPEVPEAH
CCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
AEPAAHEEAREETDAELTARFERDAIPLLDQLYGGALRMTRNPADAEDLLQETMVKAYAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHH
FRSFRAGTNLKAWLYRILTNTYINSYRKKQRQPAEYPTEEITDWQLASNAEHSSTGLRSA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHCCCCHHHCCCHHH
EVEALESLPDSEIKDALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHH
RQLRGLLADVAKERGFNRGQQTHEEVSS
HHHHHHHHHHHHHCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]