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The map label for this gene is fadD29

Identifier: 41409382

GI number: 41409382

Start: 3644143

End: 3647490

Strand: Reverse

Name: fadD29

Synonym: MAP3284c

Alternate gene names: 41409382

Gene position: 3647490-3644143 (Counterclockwise)

Preceding gene: 41409383

Following gene: 41409381

Centisome position: 75.52

GC content: 69.15

Gene sequence:

>3348_bases
TTGCTCCGCACCGGCCGGCGGGACTACATTGGTTTCATATTCATGATTGCAAGTCGTACTCGGCTGAGCCCAGCCTGGAA
AGGGGATAGCTCGACTATGGAGACGCTGATCGATTACCTGCACCTGTGGGAACAGCGCAGGCCCGAGCAAACCCTCTTCC
GGTTCGTCGACGTCGACGGCCGCGAACTTGAGCACTACACCTACCGCAGCTTCGCCGAGCGCACCCGCGAGCTGGCCGCC
TACCTGTCCACCGAGGCCGGGCTGCGGGCGGGTGACTGTGCGCTGCTGGTCTACCCGCCGGGCCTGGAGATGGTGGCGGC
CCTGTACGCCTGCGCCCGCATCGGCGTGATCGCCGTTCCGGTCAGCCCGCCGCTGCCGATGTCGTTCGAGTCCGGGCTGG
CCAAGCTCGGCTTCATCGCGCGCGACTGCCAGGCCCGGGCGGTGCTGTCGACCAAGCAGTTCGAGTACGACTTCCGGATG
CTGCTCGGTCAGCGCCACGGCGGGCAACCCTGGTCCGACGCCGGCCTGCCGGAGCTGCCCTGGTTCGCCACCGACGGCGC
CCAGGAATTCGGCGGCGCCCCGGTGCCCGACACCCCCGGCGACGTGCTGTTCCTGCAGTACACCTCGGGCTCCACCAGCG
ATCCCAAGGGCGTCATCGTCAGCCACGAAAACGTCATCGCCAACGTCTCCGCCTTCACCGGCGGCAGCGAGGTGCTGGTC
TCCTGGCTGCCGCAGCACCACGACATGGGCCTGATCTCGGCCTACATGTTCATCCTGCTGCAGGGCGGGACCACGCACGC
CATGTCGCCGCTGGACTTTTTGGCCCGGCCGTCGGCCTGGCTGCGGCTGATCAGCGACGTGCGCGCCACCCACACGCCGG
TGCCGAACTTCGCGCTCGAATACTGCCTGCGTGAGGACAAGGTGCCCGCGGCCGAGCTGGCCGGCATCGACCTGAGCAGC
CTGGAATGCATCGTCGTCGGTGCGGAACCGTTGCGCGCCAACACCTTCCACCAGTTCCGTGAGCGGTTCGCCCCGTACGG
CCTGCGGCCCGAGGCGCTGACGGGCGCCTACGGCATGGCCGAATCCACCCTGATCGTGTCCATCCGCGGGCGCCAGACGC
TGACGGTGAACAAGCGCGGCCTGGAAAAGAACGTCGCGCGGGTGGAAAAGGCGCTGCCGGAGAACAGCAACCAGGTGCCG
CTGGTCAGCTGCGGCAAGCCCCTCGAGGAAACCGTGGTCCGGGTGGTCGACCCGCAGACGCGCCAGGCGCTGGGTGAGGG
CCGAGTCGGCGAGGTGTGGCTGGCAGGACCGTCCAAGGGCCGCGGCTACTGGAACCGTCCGCAGCTCACCGCCGAGATGT
TCGAAGCCCGCCTGGCCGGCGACGACGAGCACAGCTATCTGCGCACCGGCGACCTGGGCTTCCTCTACGAGGGCGAGCTG
TTCGTCTGCGGCCGCAGCAAGGACCTGATCATCGTCCGCGGCGTCAACTGCTACCCCTCCGACATCGAGGCCGTCGTCGA
GCGCTCGGCCAAGCAGGTCCGTGGCGGCTGCGTCGCCGCGCTGTCCGTCGAGCAGGACGACCAGGAGGCGCTGGTGGTGG
TCGCCGAGGTGCGCGACGAGCACAACCTGCCGGACGCCCGGGCGTTGGCCCGCGCGATCCGCCGGCACTGCCACATCGAT
CCGCACACCATCGTGTTCGCGCCGCCGCGCAGCATCCCCAAGACCACGTCGGGCAAGATCCGCCGGGCCAGCACCCGTCA
GCTGTGGCTGGACGGCGCCCTGCCGACGTTCTCCAGCTGGGTGAACCCGGCGGCCACCCGCGGCCACGACGGGACGGCCG
CCGGGGCGGGCCCGCTGGAACGCTTCGCCAACCTCATCGAGAGCTACGACCTGACCGGCGACGAGGACTGCTCGTTCGCC
GACCTGGGTATCGACTCGTTGGCGCTGGCCGAACTGCGCAACGACATGCAGGCCCTGCTGGCCGAGCACGGCGCGGCGGA
GTTGGCCGACGAGGTCAACACGCGCCTGCTGCAGCGCCTGACGGTAGCCGAATTCTTCTCTCTGATAAGGCAATTCGGCG
AGGGTTCCGGGCAGCCGCTGGACGCGTTGCGCCGGGCGCTGGATCAGATTTCCGCCGAGTACGAGGCGCACGAGGCCGCC
CAGATGCGCGCCGACGCGGCGCTGCCGCTGCCCGACCCGGCGCCCGCCCGCGCGGGCACGCCCACCGACATCCTGCTGAC
CGGGGCGACCGGTTTCCTGGGGCCGTTCCTGCTGAGCAGCCTGTTGGCGCGGACGCCCTACACGGTGCACGCGCTGGTCC
GGGCCACCGACCCCGGGCACGGGCTGGACCGCATCGTCGCCTCGCTGCGCAAGGCCCAGCTGTGGACACCGGCGCTGGAA
GCCGAGGTGCGCGCCCGGGTGCGGGTGATCTGCGGTGATCTCGCCGAGCCCGCGCTGGGCATCGGGGAGCCGGCCTTCGC
GCGGCTGGCGCGCGACGTCGACGCCGTCGTGCACAACGGCGCGTTGGTCAACTACGTGCGCACCTACGATGCACTGCGGC
CCACCAACGTGGAGGGCACCCGAGAGTTGTTGCGGCTGGCCATGACCGACCACGCCAAGACCTTCCACCTGGTCTCCAGC
ACCTTCATCTACGGCTGGAGCACCCAGCCGGTGGTGGGAGAGTGGGACGCCAACGAGAAGATGGCGGGCCTGGACTTCGG
CTACTCGCAGACCAAGTGGGTGGCCGAGCAGTTGGCGCTGGCCGCGCAGCGGAAGGGACTCGACGTCCGCATCTACCGGC
CGTCGCTGATCTCGCCGACCCGCAGCGGCTTCGGCAGCCAGGACGACATCCTGGTGCGGCTGACCGCCTTCATGATCGAG
CACGGGCTGGCCGTCAACGCGCTCAACCAGATCAGCCTGCTGCCGGCGGATTTGATCGCCGATCACATCGTCGCGCTGAT
GGATCTGCCGGACGAGTCGGGCAGCGTGTTCAACATGACCGCCGACGACTACTACAACCTCACCGACGTGACGCGGATCC
TGTCCGAGCGGTACGGGTACCGCTTCGACTACCACGACATCGATTCGTTCGCCGAGCAGCTCAACCGGCGCTGCACGCCG
GACGACCAGATGTATCCGCTGGTCGATTTCCTCACCCGCTCGGCGGACAAGATCGCCGCGATGCGCGACAAGCGCTACGA
CAACACCCAGTACCGGCACCGGCGCGGGCTGGTCCCGGTGCGGCTGCGGGAGCCGGCGCTGACCGAAACGGTCGACCACC
TGGTGCGGTTCTTGCGCACCGAGCGGATGATCACTGAGGTGGAGGACGAGGCGCAACGCAGCGCCTGA

Upstream 100 bases:

>100_bases
AGTGCGTATCGGCGTAGCTCAGGATCGGCGTATTCAATTCGGGCGCTTCAATTCAAGCTGTGAATGCAATGTGTAATGGC
CATTAAGGCCCTCAACTGCT

Downstream 100 bases:

>100_bases
CCGGCGCGCTACTCGGAAGGGAAGACGACGATGTTCACCGTCGACGACAAGGCAACCGGCCCGCACGACGCCGCCCTCGA
TCACGAGCGGATCGTCCTGC

Product: FadD29

Products: AMP; diphosphate +an acyl-CoA [C]

Alternate protein names: Acyl-CoA synthetase [H]

Number of amino acids: Translated: 1115; Mature: 1115

Protein sequence:

>1115_residues
MLRTGRRDYIGFIFMIASRTRLSPAWKGDSSTMETLIDYLHLWEQRRPEQTLFRFVDVDGRELEHYTYRSFAERTRELAA
YLSTEAGLRAGDCALLVYPPGLEMVAALYACARIGVIAVPVSPPLPMSFESGLAKLGFIARDCQARAVLSTKQFEYDFRM
LLGQRHGGQPWSDAGLPELPWFATDGAQEFGGAPVPDTPGDVLFLQYTSGSTSDPKGVIVSHENVIANVSAFTGGSEVLV
SWLPQHHDMGLISAYMFILLQGGTTHAMSPLDFLARPSAWLRLISDVRATHTPVPNFALEYCLREDKVPAAELAGIDLSS
LECIVVGAEPLRANTFHQFRERFAPYGLRPEALTGAYGMAESTLIVSIRGRQTLTVNKRGLEKNVARVEKALPENSNQVP
LVSCGKPLEETVVRVVDPQTRQALGEGRVGEVWLAGPSKGRGYWNRPQLTAEMFEARLAGDDEHSYLRTGDLGFLYEGEL
FVCGRSKDLIIVRGVNCYPSDIEAVVERSAKQVRGGCVAALSVEQDDQEALVVVAEVRDEHNLPDARALARAIRRHCHID
PHTIVFAPPRSIPKTTSGKIRRASTRQLWLDGALPTFSSWVNPAATRGHDGTAAGAGPLERFANLIESYDLTGDEDCSFA
DLGIDSLALAELRNDMQALLAEHGAAELADEVNTRLLQRLTVAEFFSLIRQFGEGSGQPLDALRRALDQISAEYEAHEAA
QMRADAALPLPDPAPARAGTPTDILLTGATGFLGPFLLSSLLARTPYTVHALVRATDPGHGLDRIVASLRKAQLWTPALE
AEVRARVRVICGDLAEPALGIGEPAFARLARDVDAVVHNGALVNYVRTYDALRPTNVEGTRELLRLAMTDHAKTFHLVSS
TFIYGWSTQPVVGEWDANEKMAGLDFGYSQTKWVAEQLALAAQRKGLDVRIYRPSLISPTRSGFGSQDDILVRLTAFMIE
HGLAVNALNQISLLPADLIADHIVALMDLPDESGSVFNMTADDYYNLTDVTRILSERYGYRFDYHDIDSFAEQLNRRCTP
DDQMYPLVDFLTRSADKIAAMRDKRYDNTQYRHRRGLVPVRLREPALTETVDHLVRFLRTERMITEVEDEAQRSA

Sequences:

>Translated_1115_residues
MLRTGRRDYIGFIFMIASRTRLSPAWKGDSSTMETLIDYLHLWEQRRPEQTLFRFVDVDGRELEHYTYRSFAERTRELAA
YLSTEAGLRAGDCALLVYPPGLEMVAALYACARIGVIAVPVSPPLPMSFESGLAKLGFIARDCQARAVLSTKQFEYDFRM
LLGQRHGGQPWSDAGLPELPWFATDGAQEFGGAPVPDTPGDVLFLQYTSGSTSDPKGVIVSHENVIANVSAFTGGSEVLV
SWLPQHHDMGLISAYMFILLQGGTTHAMSPLDFLARPSAWLRLISDVRATHTPVPNFALEYCLREDKVPAAELAGIDLSS
LECIVVGAEPLRANTFHQFRERFAPYGLRPEALTGAYGMAESTLIVSIRGRQTLTVNKRGLEKNVARVEKALPENSNQVP
LVSCGKPLEETVVRVVDPQTRQALGEGRVGEVWLAGPSKGRGYWNRPQLTAEMFEARLAGDDEHSYLRTGDLGFLYEGEL
FVCGRSKDLIIVRGVNCYPSDIEAVVERSAKQVRGGCVAALSVEQDDQEALVVVAEVRDEHNLPDARALARAIRRHCHID
PHTIVFAPPRSIPKTTSGKIRRASTRQLWLDGALPTFSSWVNPAATRGHDGTAAGAGPLERFANLIESYDLTGDEDCSFA
DLGIDSLALAELRNDMQALLAEHGAAELADEVNTRLLQRLTVAEFFSLIRQFGEGSGQPLDALRRALDQISAEYEAHEAA
QMRADAALPLPDPAPARAGTPTDILLTGATGFLGPFLLSSLLARTPYTVHALVRATDPGHGLDRIVASLRKAQLWTPALE
AEVRARVRVICGDLAEPALGIGEPAFARLARDVDAVVHNGALVNYVRTYDALRPTNVEGTRELLRLAMTDHAKTFHLVSS
TFIYGWSTQPVVGEWDANEKMAGLDFGYSQTKWVAEQLALAAQRKGLDVRIYRPSLISPTRSGFGSQDDILVRLTAFMIE
HGLAVNALNQISLLPADLIADHIVALMDLPDESGSVFNMTADDYYNLTDVTRILSERYGYRFDYHDIDSFAEQLNRRCTP
DDQMYPLVDFLTRSADKIAAMRDKRYDNTQYRHRRGLVPVRLREPALTETVDHLVRFLRTERMITEVEDEAQRSA
>Mature_1115_residues
MLRTGRRDYIGFIFMIASRTRLSPAWKGDSSTMETLIDYLHLWEQRRPEQTLFRFVDVDGRELEHYTYRSFAERTRELAA
YLSTEAGLRAGDCALLVYPPGLEMVAALYACARIGVIAVPVSPPLPMSFESGLAKLGFIARDCQARAVLSTKQFEYDFRM
LLGQRHGGQPWSDAGLPELPWFATDGAQEFGGAPVPDTPGDVLFLQYTSGSTSDPKGVIVSHENVIANVSAFTGGSEVLV
SWLPQHHDMGLISAYMFILLQGGTTHAMSPLDFLARPSAWLRLISDVRATHTPVPNFALEYCLREDKVPAAELAGIDLSS
LECIVVGAEPLRANTFHQFRERFAPYGLRPEALTGAYGMAESTLIVSIRGRQTLTVNKRGLEKNVARVEKALPENSNQVP
LVSCGKPLEETVVRVVDPQTRQALGEGRVGEVWLAGPSKGRGYWNRPQLTAEMFEARLAGDDEHSYLRTGDLGFLYEGEL
FVCGRSKDLIIVRGVNCYPSDIEAVVERSAKQVRGGCVAALSVEQDDQEALVVVAEVRDEHNLPDARALARAIRRHCHID
PHTIVFAPPRSIPKTTSGKIRRASTRQLWLDGALPTFSSWVNPAATRGHDGTAAGAGPLERFANLIESYDLTGDEDCSFA
DLGIDSLALAELRNDMQALLAEHGAAELADEVNTRLLQRLTVAEFFSLIRQFGEGSGQPLDALRRALDQISAEYEAHEAA
QMRADAALPLPDPAPARAGTPTDILLTGATGFLGPFLLSSLLARTPYTVHALVRATDPGHGLDRIVASLRKAQLWTPALE
AEVRARVRVICGDLAEPALGIGEPAFARLARDVDAVVHNGALVNYVRTYDALRPTNVEGTRELLRLAMTDHAKTFHLVSS
TFIYGWSTQPVVGEWDANEKMAGLDFGYSQTKWVAEQLALAAQRKGLDVRIYRPSLISPTRSGFGSQDDILVRLTAFMIE
HGLAVNALNQISLLPADLIADHIVALMDLPDESGSVFNMTADDYYNLTDVTRILSERYGYRFDYHDIDSFAEQLNRRCTP
DDQMYPLVDFLTRSADKIAAMRDKRYDNTQYRHRRGLVPVRLREPALTETVDHLVRFLRTERMITEVEDEAQRSA

Specific function: Esterification, Concomitant With Transport, Of Exogenous Long-Chain Fatty Acids Into Metabolically Active CoA Thioesters For Subsequent Degradation Or Incorporation Into Phospholipids. [C]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI44888818, Length=555, Percent_Identity=24.8648648648649, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI225735629, Length=551, Percent_Identity=26.3157894736842, Blast_Score=143, Evalue=8e-34,
Organism=Homo sapiens, GI45827692, Length=551, Percent_Identity=26.3157894736842, Blast_Score=143, Evalue=8e-34,
Organism=Homo sapiens, GI55749758, Length=553, Percent_Identity=25.1356238698011, Blast_Score=138, Evalue=4e-32,
Organism=Homo sapiens, GI225735625, Length=606, Percent_Identity=24.7524752475248, Blast_Score=113, Evalue=9e-25,
Organism=Homo sapiens, GI45827694, Length=554, Percent_Identity=24.9097472924188, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI225735627, Length=506, Percent_Identity=24.703557312253, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI45827696, Length=506, Percent_Identity=24.703557312253, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI45827698, Length=487, Percent_Identity=24.2299794661191, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI156151445, Length=604, Percent_Identity=23.3443708609272, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI42794756, Length=497, Percent_Identity=22.7364185110664, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI42794760, Length=497, Percent_Identity=22.7364185110664, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI42794758, Length=497, Percent_Identity=22.7364185110664, Blast_Score=77, Evalue=1e-13,
Organism=Escherichia coli, GI1788107, Length=584, Percent_Identity=26.541095890411, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI145693145, Length=588, Percent_Identity=24.6598639455782, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193202679, Length=607, Percent_Identity=21.4168039538715, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17531443, Length=590, Percent_Identity=21.5254237288136, Blast_Score=105, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17559526, Length=473, Percent_Identity=23.6786469344609, Blast_Score=93, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6319591, Length=340, Percent_Identity=29.1176470588235, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24654656, Length=526, Percent_Identity=23.384030418251, Blast_Score=132, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24581924, Length=613, Percent_Identity=22.3491027732463, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356947, Length=402, Percent_Identity=23.134328358209, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21356441, Length=335, Percent_Identity=23.5820895522388, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: 6.2.1.3 [C]

Molecular weight: Translated: 123212; Mature: 123212

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTGRRDYIGFIFMIASRTRLSPAWKGDSSTMETLIDYLHLWEQRRPEQTLFRFVDVDG
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
RELEHYTYRSFAERTRELAAYLSTEAGLRAGDCALLVYPPGLEMVAALYACARIGVIAVP
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEEC
VSPPLPMSFESGLAKLGFIARDCQARAVLSTKQFEYDFRMLLGQRHGGQPWSDAGLPELP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
WFATDGAQEFGGAPVPDTPGDVLFLQYTSGSTSDPKGVIVSHENVIANVSAFTGGSEVLV
CEECCCHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCEEEEEHHCCCCHHHHH
SWLPQHHDMGLISAYMFILLQGGTTHAMSPLDFLARPSAWLRLISDVRATHTPVPNFALE
HHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHH
YCLREDKVPAAELAGIDLSSLECIVVGAEPLRANTFHQFRERFAPYGLRPEALTGAYGMA
HHHHHCCCCHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCC
ESTLIVSIRGRQTLTVNKRGLEKNVARVEKALPENSNQVPLVSCGKPLEETVVRVVDPQT
CCEEEEEECCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHCCCHH
RQALGEGRVGEVWLAGPSKGRGYWNRPQLTAEMFEARLAGDDEHSYLRTGDLGFLYEGEL
HHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCE
FVCGRSKDLIIVRGVNCYPSDIEAVVERSAKQVRGGCVAALSVEQDDQEALVVVAEVRDE
EEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEEHHCC
HNLPDARALARAIRRHCHIDPHTIVFAPPRSIPKTTSGKIRRASTRQLWLDGALPTFSSW
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEECCCCEEEECCCCHHHHHH
VNPAATRGHDGTAAGAGPLERFANLIESYDLTGDEDCSFADLGIDSLALAELRNDMQALL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHH
AEHGAAELADEVNTRLLQRLTVAEFFSLIRQFGEGSGQPLDALRRALDQISAEYEAHEAA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QMRADAALPLPDPAPARAGTPTDILLTGATGFLGPFLLSSLLARTPYTVHALVRATDPGH
HHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
GLDRIVASLRKAQLWTPALEAEVRARVRVICGDLAEPALGIGEPAFARLARDVDAVVHNG
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
ALVNYVRTYDALRPTNVEGTRELLRLAMTDHAKTFHLVSSTFIYGWSTQPVVGEWDANEK
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHEEEHHEEEECCCCCCEEECCCCCCC
MAGLDFGYSQTKWVAEQLALAAQRKGLDVRIYRPSLISPTRSGFGSQDDILVRLTAFMIE
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHCCCCCCCHHHHHHHHHHHH
HGLAVNALNQISLLPADLIADHIVALMDLPDESGSVFNMTADDYYNLTDVTRILSERYGY
CCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCC
RFDYHDIDSFAEQLNRRCTPDDQMYPLVDFLTRSADKIAAMRDKRYDNTQYRHRRGLVPV
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHCCCCEE
RLREPALTETVDHLVRFLRTERMITEVEDEAQRSA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLRTGRRDYIGFIFMIASRTRLSPAWKGDSSTMETLIDYLHLWEQRRPEQTLFRFVDVDG
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
RELEHYTYRSFAERTRELAAYLSTEAGLRAGDCALLVYPPGLEMVAALYACARIGVIAVP
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEEC
VSPPLPMSFESGLAKLGFIARDCQARAVLSTKQFEYDFRMLLGQRHGGQPWSDAGLPELP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
WFATDGAQEFGGAPVPDTPGDVLFLQYTSGSTSDPKGVIVSHENVIANVSAFTGGSEVLV
CEECCCHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCEEEEEHHCCCCHHHHH
SWLPQHHDMGLISAYMFILLQGGTTHAMSPLDFLARPSAWLRLISDVRATHTPVPNFALE
HHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHH
YCLREDKVPAAELAGIDLSSLECIVVGAEPLRANTFHQFRERFAPYGLRPEALTGAYGMA
HHHHHCCCCHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCC
ESTLIVSIRGRQTLTVNKRGLEKNVARVEKALPENSNQVPLVSCGKPLEETVVRVVDPQT
CCEEEEEECCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHCCCHH
RQALGEGRVGEVWLAGPSKGRGYWNRPQLTAEMFEARLAGDDEHSYLRTGDLGFLYEGEL
HHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCE
FVCGRSKDLIIVRGVNCYPSDIEAVVERSAKQVRGGCVAALSVEQDDQEALVVVAEVRDE
EEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEEHHCC
HNLPDARALARAIRRHCHIDPHTIVFAPPRSIPKTTSGKIRRASTRQLWLDGALPTFSSW
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEECCCCEEEECCCCHHHHHH
VNPAATRGHDGTAAGAGPLERFANLIESYDLTGDEDCSFADLGIDSLALAELRNDMQALL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHH
AEHGAAELADEVNTRLLQRLTVAEFFSLIRQFGEGSGQPLDALRRALDQISAEYEAHEAA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QMRADAALPLPDPAPARAGTPTDILLTGATGFLGPFLLSSLLARTPYTVHALVRATDPGH
HHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
GLDRIVASLRKAQLWTPALEAEVRARVRVICGDLAEPALGIGEPAFARLARDVDAVVHNG
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
ALVNYVRTYDALRPTNVEGTRELLRLAMTDHAKTFHLVSSTFIYGWSTQPVVGEWDANEK
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHEEEHHEEEECCCCCCEEECCCCCCC
MAGLDFGYSQTKWVAEQLALAAQRKGLDVRIYRPSLISPTRSGFGSQDDILVRLTAFMIE
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHCCCCCCCHHHHHHHHHHHH
HGLAVNALNQISLLPADLIADHIVALMDLPDESGSVFNMTADDYYNLTDVTRILSERYGY
CCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCC
RFDYHDIDSFAEQLNRRCTPDDQMYPLVDFLTRSADKIAAMRDKRYDNTQYRHRRGLVPV
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHCCCCEE
RLREPALTETVDHLVRFLRTERMITEVEDEAQRSA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Salts [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.0408 {octanoate}} 0.0125 {octanoate}} 0.0059 {octanoate}} 0.00072 {octanoate}} 0.0013 {undecanoate}} 0.0022 {pentadecanoate}} 0.053 {CoA}} 0.035 {CoA}} 0.034 {CoA}} 0.0034 {tridecanoate}} 0.002 {laurate}} 0.0019 {laurate}} 0.0

Substrates: ATP; a long-chain carboxylic acid; CoA [C]

Specific reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate +an acyl-CoA [C]

General reaction: Acid-thiol ligation; Phosphorylation [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]