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The map label for this gene is ophA1 [H]

Identifier: 41409379

GI number: 41409379

Start: 3641187

End: 3642275

Strand: Reverse

Name: ophA1 [H]

Synonym: MAP3281c

Alternate gene names: 41409379

Gene position: 3642275-3641187 (Counterclockwise)

Preceding gene: 41409380

Following gene: 41409378

Centisome position: 75.41

GC content: 70.89

Gene sequence:

>1089_bases
GTGAGGATGACTATGGCACAAGCGATTTGGGAAAACATTCCGGCCGACCTGTACGGCCGCCGCAAACGCGACCGGATGTA
CACGGCGTTGTACGGCGTGGGTGCGCTGTTCGGCGGCCTGGCGTCGGCGTCGCGGTGGACACCCGCGCGGGTGGTTCCGG
TGCGCCGGACCACCACCGCGGTGGTCACCCAGCGCGAGGAGCTCGCACCCGACGTGGTCGCCTTCACGCTGGCCGACCCG
CACGGCGGCCTGTTGCCGTCCTGGACGCCGGGCGCGCACATCGACGTCCGGTTGCCGTCGGGCCGGCGCCGGCAGTATTC
GCTGTGCGGCCCGCCCGGACGGCGCACCGACTACCGAATCGCGGTGCGGCGCATCGAAGACGGCGGTGGCGGCTCGATCG
AGATGCACGACACCTTCAGGGTGGGCGACGCCCTCGAGTTCGAGGGTCCCCGCAACGCGTTCTATCTCGTCACCGACGAG
CGTGACGTGTTGTTCGTGATCGGCGGCATCGGGGTGACGCCGATCCTGCCGATGATCCAGACCGCCCAGCAGCACGGGAT
CAATTGGCGCGCCGTGTACGCCGGGCGCAGCCGCGACGACATGCCGCTGCTGGACGAGGTCGTGGCCGTGGCGCCCGAGC
GGGTCAGCGTGTGGGCCGACGACGAGCGCGGCCGAATCCCCACCGCCGCAGACCTGCTCGCCGAGGCCGGGCCGGCGACC
GCCGTGTACGTGTGCGGGCCCACCGCCATGCTGGAAGCGGTGCGCACCGCGCGCGACGAACACGCCGACGCGCCACTGCA
CTACGAGCGGTTCGGGCCGCCGCCGGTGGTCGACGGCGTCCCGTTCGAGCTGGAACTGGCCCGCTCGCGGCGGGTGCTCA
CGGTGCCGGGGAACCGCTCGGCGCTGGAAGTCATGCTCGACCGCGATCCGGCCACCCCGTATTCCTGCCAGCAGGGATTC
TGCGGCACCTGCAAGGTGAAGGTGCTTGCCGGGCAAGTGGATCGGCGCGGGCGCACCGTCGAGGGCGACGACGAAATGCT
GGTCTGCGTCTCCAGGGCGAAAAACGACCGCCTGGTCATCGACGCCTGA

Upstream 100 bases:

>100_bases
ACTGGGTGGTCAACTCCCATCCCGACGTCATCGCCCGGCTCACCGGCGACTGGGTCGACCTGACGACGCGGCCGGCGGGC
GGCCACCACACGGGACAGAC

Downstream 100 bases:

>100_bases
TCTATCCGCCCGCGCCCCGGTGTTGCGCCGCCGGATCTGCGCGCGGCGTGCAGAATGAGCGGGTGCAGGGATTCGGCTTC
CACACCCTGGCGCTGCTGAC

Product: hypothetical protein

Products: NA

Alternate protein names: PDR [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MRMTMAQAIWENIPADLYGRRKRDRMYTALYGVGALFGGLASASRWTPARVVPVRRTTTAVVTQREELAPDVVAFTLADP
HGGLLPSWTPGAHIDVRLPSGRRRQYSLCGPPGRRTDYRIAVRRIEDGGGGSIEMHDTFRVGDALEFEGPRNAFYLVTDE
RDVLFVIGGIGVTPILPMIQTAQQHGINWRAVYAGRSRDDMPLLDEVVAVAPERVSVWADDERGRIPTAADLLAEAGPAT
AVYVCGPTAMLEAVRTARDEHADAPLHYERFGPPPVVDGVPFELELARSRRVLTVPGNRSALEVMLDRDPATPYSCQQGF
CGTCKVKVLAGQVDRRGRTVEGDDEMLVCVSRAKNDRLVIDA

Sequences:

>Translated_362_residues
MRMTMAQAIWENIPADLYGRRKRDRMYTALYGVGALFGGLASASRWTPARVVPVRRTTTAVVTQREELAPDVVAFTLADP
HGGLLPSWTPGAHIDVRLPSGRRRQYSLCGPPGRRTDYRIAVRRIEDGGGGSIEMHDTFRVGDALEFEGPRNAFYLVTDE
RDVLFVIGGIGVTPILPMIQTAQQHGINWRAVYAGRSRDDMPLLDEVVAVAPERVSVWADDERGRIPTAADLLAEAGPAT
AVYVCGPTAMLEAVRTARDEHADAPLHYERFGPPPVVDGVPFELELARSRRVLTVPGNRSALEVMLDRDPATPYSCQQGF
CGTCKVKVLAGQVDRRGRTVEGDDEMLVCVSRAKNDRLVIDA
>Mature_362_residues
MRMTMAQAIWENIPADLYGRRKRDRMYTALYGVGALFGGLASASRWTPARVVPVRRTTTAVVTQREELAPDVVAFTLADP
HGGLLPSWTPGAHIDVRLPSGRRRQYSLCGPPGRRTDYRIAVRRIEDGGGGSIEMHDTFRVGDALEFEGPRNAFYLVTDE
RDVLFVIGGIGVTPILPMIQTAQQHGINWRAVYAGRSRDDMPLLDEVVAVAPERVSVWADDERGRIPTAADLLAEAGPAT
AVYVCGPTAMLEAVRTARDEHADAPLHYERFGPPPVVDGVPFELELARSRRVLTVPGNRSALEVMLDRDPATPYSCQQGF
CGTCKVKVLAGQVDRRGRTVEGDDEMLVCVSRAKNDRLVIDA

Specific function: Component of the electron transfer chain involved in pyridine nucleotide-dependent dihydroxylation of phthalate. Utilizes FMN to mediate electron transfer from the two-electron donor, NADH, to the one-electron acceptor, (2Fe-2S) [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788104, Length=312, Percent_Identity=36.5384615384615, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1788903, Length=234, Percent_Identity=29.4871794871795, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787658, Length=287, Percent_Identity=27.8745644599303, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321673, Length=244, Percent_Identity=29.0983606557377, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39746; Mature: 39746

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMTMAQAIWENIPADLYGRRKRDRMYTALYGVGALFGGLASASRWTPARVVPVRRTTTA
CCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEE
VVTQREELAPDVVAFTLADPHGGLLPSWTPGAHIDVRLPSGRRRQYSLCGPPGRRTDYRI
EEECHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCEEE
AVRRIEDGGGGSIEMHDTFRVGDALEFEGPRNAFYLVTDERDVLFVIGGIGVTPILPMIQ
EEEEEECCCCCEEEEECEEECCCEEECCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHH
TAQQHGINWRAVYAGRSRDDMPLLDEVVAVAPERVSVWADDERGRIPTAADLLAEAGPAT
HHHHHCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHCCCCCE
AVYVCGPTAMLEAVRTARDEHADAPLHYERFGPPPVVDGVPFELELARSRRVLTVPGNRS
EEEEECCHHHHHHHHHHHHHCCCCCEEHHHCCCCCCCCCCCCEEEECCCCEEEECCCCCC
ALEVMLDRDPATPYSCQQGFCGTCKVKVLAGQVDRRGRTVEGDDEMLVCVSRAKNDRLVI
EEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEECCCCCEEEEEECCCCCEEEE
DA
EC
>Mature Secondary Structure
MRMTMAQAIWENIPADLYGRRKRDRMYTALYGVGALFGGLASASRWTPARVVPVRRTTTA
CCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEE
VVTQREELAPDVVAFTLADPHGGLLPSWTPGAHIDVRLPSGRRRQYSLCGPPGRRTDYRI
EEECHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCEEE
AVRRIEDGGGGSIEMHDTFRVGDALEFEGPRNAFYLVTDERDVLFVIGGIGVTPILPMIQ
EEEEEECCCCCEEEEECEEECCCEEECCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHH
TAQQHGINWRAVYAGRSRDDMPLLDEVVAVAPERVSVWADDERGRIPTAADLLAEAGPAT
HHHHHCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHCCCCCE
AVYVCGPTAMLEAVRTARDEHADAPLHYERFGPPPVVDGVPFELELARSRRVLTVPGNRS
EEEEECCHHHHHHHHHHHHHCCCCCEEHHHCCCCCCCCCCCCEEEECCCCEEEECCCCCC
ALEVMLDRDPATPYSCQQGFCGTCKVKVLAGQVDRRGRTVEGDDEMLVCVSRAKNDRLVI
EEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEECCCCCEEEEEECCCCCEEEE
DA
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FMN. [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9851995; 1280857 [H]